KEGG   REACTION: R08959
Entry
R08959                      Reaction                               
Name
5alpha-pregnane-3alpha,20alpha-diol:NADP+ 20-oxidoreductase
Definition
5alpha-Pregnane-3alpha,20alpha-diol + NADP+ <=> Allopregnanolone + NADPH + H+
Equation
C18042 + C00006 <=> C13712 + C00005 + C00080
Reaction class
RC00001  C00005_C00006
RC00139  C13712_C18042
Enzyme
1.1.1.149
Pathway
rn00140  Steroid hormone biosynthesis
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.149
     R08959  5alpha-Pregnane-3alpha,20alpha-diol + NADP+ <=> Allopregnanolone + NADPH + H+
Orthology
K00212  20alpha/3alpha-hydroxysteroid dehydrogenase / dihydrodiol dehydrogenase [EC:1.1.1.149 1.1.1.357 1.3.1.20]
K05295  20alpha-hydroxysteroid dehydrogenase [EC:1.1.1.149]

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Ontology (1)   
   KEGG BRITE (1)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG RCLASS (2)   
Gene (98)   
   KEGG ORTHOLOGY (2)   
   KEGG GENES (96)   
All databases (111)   

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