KEGG   REACTION: R09259
Entry
R09259                      Reaction                               
Definition
3,5,7,9,11,13,15-Heptaoxo-hexadecanoyl-[acp] <=> 7,9,12-Octaketide intermediate 1
Equation
C12348 <=> C18327
Reaction class
RC02545  C12348_C18327
Pathway
rn01056  Biosynthesis of type II polyketide backbone
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00778  Type II polyketide backbone biosynthesis, acyl-CoA + malonyl-CoA => polyketide
Orthology
K05551  minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.- 2.3.1.260 2.3.1.235]
K05552  minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.- 2.3.1.260 2.3.1.235]
K05553  minimal PKS acyl carrier protein
Reference
1  [PMID:15286722]
  Authors
Keatinge-Clay AT, Maltby DA, Medzihradszky KF, Khosla C, Stroud RM
  Title
An antibiotic factory caught in action.
  Journal
Nat Struct Mol Biol 11:888-93 (2004)
DOI:10.1038/nsmb808

  All links  
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