KEGG   REACTION: R10054
Entry
R10054                      Reaction                               

Name
L-lysine:NAD+ 6-oxidoreductase (deaminating)
Definition
L-Lysine + NAD+ <=> (S)-2,3,4,5-Tetrahydropyridine-2-carboxylate + NADH + H+ + Ammonia
Equation
Comment
two-step reaction (see R00446+R02317)
Reaction class
RC00001  C00003_C00004
RC00353  C00047_C00450
Enzyme
Other DBs
RHEA: 12411

KEGG   REACTION: R00446
Entry
R00446                      Reaction                               

Name
L-lysine:NAD+ 6-oxidoreductase (deaminating)
Definition
L-Lysine + NAD+ + H2O <=> L-2-Aminoadipate 6-semialdehyde + NADH + Ammonia + H+
Equation
Comment
first step of two-step reaction (see R10054, R00446+R02317)
Reaction class
RC00001  C00003_C00004
RC00062  C00047_C04076
Enzyme
Pathway
rn00960  Tropane, piperidine and pyridine alkaloid biosynthesis
rn01100  Metabolic pathways
Orthology
K19064  lysine 6-dehydrogenase [EC:1.4.1.18]
Other DBs
RHEA: 25120

KEGG   REACTION: R02317
Entry
R02317                      Reaction                               

Name
(S)-2-amino-6-oxohexanoate hydro-lyase (spontaneous)
Definition
(S)-2,3,4,5-Tetrahydropyridine-2-carboxylate + H2O <=> L-2-Aminoadipate 6-semialdehyde
Equation
Comment
spontaneous
second step of two-step reaction (see R10054, R00446+R02317)
first step of two-step reaction (see R03102, R02317+R11231)
first step of two-step reaction (see R03103, R02317+R11232)
Reaction class
RC00694  C00450_C04076
Enzyme
1.2.1.31        1.4.1.18
Pathway
rn00960  Tropane, piperidine and pyridine alkaloid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Orthology
K19064  lysine 6-dehydrogenase [EC:1.4.1.18]
Other DBs
RHEA: 25124

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