KEGG   REACTION: R10242
Entry
R10242                      Reaction                               
Name
5alpha-androstane-3,17-dione:NADP+ delta4-oxidoreductase
Definition
5alpha-Androstane-3,17-dione + NADP+ <=> Androstenedione + NADPH + H+
Equation
C00674 + C00006 <=> C00280 + C00005 + C00080
Reaction class
RC00001  C00005_C00006
RC00145  C00280_C00674
Enzyme
1.3.1.22
Pathway
rn00140  Steroid hormone biosynthesis
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.22
     R10242  5alpha-Androstane-3,17-dione + NADP+ <=> Androstenedione + NADPH + H+
IUBMB reaction hierarchy [BR:br08202]
 1. Oxidoreductase reactions
  1.3.1.22
   R13214  3-Oxo-5alpha-steroid <=> 3-Oxo-Delta4-steroid
    R10242  5alpha-Androstane-3,17-dione <=> Androstenedione
Orthology
K12343  3-oxo-5-alpha-steroid 4-dehydrogenase 1 [EC:1.3.1.22]
K12344  3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:1.3.1.22]
K12345  3-oxo-5-alpha-steroid 4-dehydrogenase 3 / polyprenol reductase [EC:1.3.1.22 1.3.1.94]
Other DBs
RHEA: 50819

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG RCLASS (2)   
Gene (2333)   
   KEGG ORTHOLOGY (3)   
   KEGG GENES (2330)   
All databases (2347)   

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