KEGG   REACTION: R10634Help
Entry
R10634                      Reaction                               

Definition
NAD+ + Protein N6-acetyl-L-lysine + H2O <=> Nicotinamide + Protein lysine + O-Acetyl-ADP-ribose + H+
Equation
Comment
Sirtuin
Reaction class
RC00033  C00003_C00153
RC00096  C02188_C20743
Enzyme
Pathway
rn00760  Nicotinate and nicotinamide metabolism
rn01100  Metabolic pathways
Orthology
K11121  NAD+-dependent protein deacetylase SIR2 [EC:2.3.1.286]
K11411  NAD+-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K11412  NAD+-dependent protein deacetylase sirtuin 2 [EC:2.3.1.286]
K11413  NAD+-dependent protein deacetylase sirtuin 3 [EC:2.3.1.286]
K11414  NAD+-dependent protein deacetylase sirtuin 4 [EC:2.3.1.286]
K11415  NAD+-dependent protein deacetylase sirtuin 5 [EC:2.3.1.286]
K11416  NAD+-dependent protein deacetylase sirtuin 6 [EC:2.3.1.286]
K11417  NAD+-dependent protein deacetylase sirtuin 7 [EC:2.3.1.286]

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