KEGG   REACTION: R10671Help
Entry
R10671                      Reaction                               

Name
L-tyrosine,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase (N-hydroxylating)
Definition
L-Tyrosine + 2 Oxygen + 2 [Reduced NADPH---hemoprotein reductase] <=> (E)-4-Hydroxyphenylacetaldehyde oxime + 2 [Oxidized NADPH---hemoprotein reductase] + 3 H2O + CO2
Equation
C00082 + 2 C00007 + 2 C03024 <=> C04350 + 2 C03161 + 3 C00001 + C00011
Comment
three-step reaction (see R00730+R04460+R07190, similar to R09578, R09579+R09580+R09581)
Reaction class
RC02295  C00082_C04350
Enzyme
Pathway
rn00966  Glucosinolate biosynthesis
rn01110  Biosynthesis of secondary metabolites
rn01210  2-Oxocarboxylic acid metabolism
Orthology
K13027  tyrosine N-monooxygenase [EC:1.14.14.36]
Other DBs
RHEA: 32314

KEGG   REACTION: R00730Help
Entry
R00730                      Reaction                               

Name
L-tyrosine,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase (N-hydroxylating)
Definition
L-Tyrosine + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> N-Hydroxy-L-tyrosine + [Oxidized NADPH---hemoprotein reductase] + H2O
Equation
Comment
first step of three-step reaction (see R10671, R00730+R04460+R07190)
Reaction class
RC00365  C00082_C03004
Enzyme
Pathway
rn00460  Cyanoamino acid metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00369  Cyanogenic glycoside biosynthesis, tyrosine => dhurrin
Orthology
K13027  tyrosine N-monooxygenase [EC:1.14.14.36]
Other DBs
RHEA: 22467

KEGG   REACTION: R04460Help
Entry
R04460                      Reaction                               

Name
N-hydroxy-L-tyrosine,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase (N-hydroxylating)
Definition
N-Hydroxy-L-tyrosine + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> N,N-Dihydroxy-L-tyrosine + [Oxidized NADPH---hemoprotein reductase] + H2O
Equation
Comment
first step of two-step reaction (R04460+R07190 or R06585), subsequently R07190
and second step of three-step reaction (see R10671, R00730+R04460+R07190)
Reaction class
RC00001  C00005_C00006
RC01918  C03004_C15503
Enzyme
Pathway
rn00460  Cyanoamino acid metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00369  Cyanogenic glycoside biosynthesis, tyrosine => dhurrin
Orthology
K13027  tyrosine N-monooxygenase [EC:1.14.14.36]
Other DBs
RHEA: 24063

KEGG   REACTION: R07190Help
Entry
R07190                      Reaction                               

Definition
N,N-Dihydroxy-L-tyrosine <=> (E)-4-Hydroxyphenylacetaldehyde oxime + CO2 + H2O
Equation
Comment
second step of two-step reaction (R04460+R07190 or R06585), following after R04460
and last step of three-step reaction (see R10671, R00730+R04460+R07190)
Enzyme
Pathway
rn00460  Cyanoamino acid metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00369  Cyanogenic glycoside biosynthesis, tyrosine => dhurrin
Orthology
K13027  tyrosine N-monooxygenase [EC:1.14.14.36]
Other DBs
RHEA: 23047

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