REACTION: R10825
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Entry
R10825 Reaction
Name
very-long-chain acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating)
Definition
Very-long-chain acyl-CoA + Malonyl-CoA <=> Very-long-chain 3-oxoacyl-CoA + CO2 + CoA
Equation
C20876
+
C00083
<=>
C20877
+
C00011
+
C00010
Comment
Elongation of C16/C18 acyl-CoAs to very-long-chain acyl CoAs.
Reaction class
RC00004
C00010_C20876
RC02888
C00083_C20877
Enzyme
2.3.1.199
Pathway
rn00062
Fatty acid elongation
rn01100
Metabolic pathways
rn01110
Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:
br08201
]
2. Transferase reactions
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.199
R10825 Very-long-chain acyl-CoA + Malonyl-CoA <=> Very-long-chain 3-oxoacyl-CoA + CO2 + CoA
BRITE hierarchy
Orthology
K10203
elongation of very long chain fatty acids protein 6 [EC:
2.3.1.199
]
K10205
elongation of very long chain fatty acids protein 2 [EC:
2.3.1.199
]
K10244
elongation of very long chain fatty acids protein 5 [EC:
2.3.1.199
]
K10245
fatty acid elongase 2 [EC:
2.3.1.199
]
K10246
fatty acid elongase 3 [EC:
2.3.1.199
]
K10247
elongation of very long chain fatty acids protein 1 [EC:
2.3.1.199
]
K10248
elongation of very long chain fatty acids protein 3 [EC:
2.3.1.199
]
K10249
elongation of very long chain fatty acids protein 4 [EC:
2.3.1.199
]
K10250
elongation of very long chain fatty acids protein 7 [EC:
2.3.1.199
]
K15397
3-ketoacyl-CoA synthase [EC:
2.3.1.199
]
Other DBs
RHEA:
32730
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