KEGG   REACTION: R11175
Entry
R11175                      Reaction                               
Name
(S)-nicotine:cytochrome c oxidoreductase (N-methylmimosine-forming)
Definition
Nicotine + 2 Ferricytochrome c <=> N-Methylmyosmine + 2 Ferrocytochrome c + 2 H+
Equation
C00745 + 2 C00125 <=> C21154 + 2 C00126 + 2 C00080
Comment
first step of two-step reaction (see R11177, R11175+R11176)
Enzyme
1.4.2.2
Pathway
rn00760  Nicotinate and nicotinamide metabolism
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Module
M00811  Nicotine degradation, pyrrolidine pathway, nicotine => succinate semialdehyde
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.4  Acting on the CH-NH2 group of donors
   1.4.2  With a cytochrome as acceptor
    1.4.2.2
     R11175  Nicotine + 2 Ferricytochrome c <=> N-Methylmyosmine + 2 Ferrocytochrome c + 2 H+
Orthology
K20169  nicotine dehydrogenase [EC:1.4.2.2]
Reference
1  [PMID:24204321]
  Authors
Tang H, Wang L, Wang W, Yu H, Zhang K, Yao Y, Xu P
  Title
Systematic unraveling of the unsolved pathway of nicotine degradation in Pseudomonas.
  Journal
PLoS Genet 9:e1003923 (2013)
DOI:10.1371/journal.pgen.1003923

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Gene (9)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (8)   
All databases (23)   

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