KEGG   REACTION: R11268
Entry
R11268                      Reaction                               
Name
kanamycin-C:oxygen 6'-oxidoreductase
Definition
Kanamycin C + Oxygen <=> 6'-Oxokanamycin C + Hydrogen peroxide
Equation
Reaction class
RC00450  C01823_C21252
Enzyme
1.1.3.-
Pathway
rn00524  Neomycin, kanamycin and gentamicin biosynthesis
rn01110  Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.3  With oxygen as acceptor
    1.1.3.-
     R11268  Kanamycin C + Oxygen <=> 6'-Oxokanamycin C + Hydrogen peroxide
Orthology
K20566  paromamine 6'-oxidase / 2'-deamino-2'-hydroxyparomamine 6'-oxidase [EC:1.1.3.43 1.1.3.-]
Reference
1  [PMID:21983602]
  Authors
Park JW, Park SR, Nepal KK, Han AR, Ban YH, Yoo YJ, Kim EJ, Kim EM, Kim D, Sohng JK, Yoon YJ
  Title
Discovery of parallel pathways of kanamycin biosynthesis allows antibiotic manipulation.
  Journal
Nat Chem Biol 7:843-52 (2011)
DOI:10.1038/nchembio.671

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