KEGG   REACTION: R11270
Entry
R11270                      Reaction                               

Name
kanamycin-B:2-oxoglutarate aminotransferase
Definition
Kanamycin B + 2-Oxoglutarate <=> 6'-Oxokanamycin C + L-Glutamate
Equation
Reaction class
RC00006  C00025_C00026
RC02401  C00825_C21252
Enzyme
Pathway
rn00524  Neomycin, kanamycin and gentamicin biosynthesis
rn01110  Biosynthesis of secondary metabolites
Orthology
K20568  neamine transaminase / 2'-deamino-2'-hydroxyneamine transaminase [EC:2.6.1.93 2.6.1.94]
Reference
1  [PMID:21983602]
  Authors
Park JW, Park SR, Nepal KK, Han AR, Ban YH, Yoo YJ, Kim EJ, Kim EM, Kim D, Sohng JK, Yoon YJ
  Title
Discovery of parallel pathways of kanamycin biosynthesis allows antibiotic manipulation.
  Journal
Nat Chem Biol 7:843-52 (2011)
DOI:10.1038/nchembio.671

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