KEGG   REACTION: R12352Help
Entry
R12352                      Reaction                               

Definition
N3-Fumaroyl-L-2,3-diaminopropanoate + L-Glutamine + ATP + H2O <=> 3-{[(2E)-4-Amino-4-oxobut-2-enoyl]amino}-L-alanine + L-Glutamate + ADP + Orthophosphate
Equation
Comment
proposed pathway
not yet characterized sufficiently
Enzyme
6.3.5.-
Pathway
rn00997  Biosynthesis of various secondary metabolites - part 3
Orthology
K01957  N-3-fumaroyl-(S)-2,3-diaminopropanoate amidotransferase [EC:6.3.5.-]
Reference
1  [PMID:19807062]
  Authors
Hollenhorst MA, Clardy J, Walsh CT
  Title
The ATP-dependent amide ligases DdaG and DdaF assemble the fumaramoyl-dipeptide scaffold of the dapdiamide antibiotics.
  Journal
Biochemistry 48:10467-72 (2009)
DOI:10.1021/bi9013165

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