KEGG   REACTION: R12625
Entry
R12625                      Reaction                               

Name
(Z)-3-ureidoacrylate amidohydrolase
Definition
Ureidoacrylate + H2O <=> Aminoacrylate + CO2 + Ammonia
Equation
Comment
two-step reaction (see R09980+R07316)
Reaction class
RC02737  C20253_C20254
Enzyme

KEGG   REACTION: R09980
Entry
R09980                      Reaction                               

Name
ureidoacrylate amidohydrolase
Definition
Ureidoacrylate + H2O <=> Aminoacrylate + Carbamate
Equation
Comment
the first step of two-step reaction (see R12625, R09980+R07316)
Reaction class
RC02737  C20253_C20254
RC02738  C01563_C20254
Enzyme
Pathway
rn00240  Pyrimidine metabolism
rn01100  Metabolic pathways
Orthology
K09020  ureidoacrylate peracid hydrolase [EC:3.5.1.110]

KEGG   REACTION: R07316
Entry
R07316                      Reaction                               

Definition
Carbamate <=> Ammonia + CO2
Equation
Comment
spontaneous
the second step of two-step reaction (see R12625, R09980+R07316 or R12623, R12624+R07316 or R10079, R03546+R07316)
Enzyme
3.5.1.110       4.2.1.104
Pathway
rn00910  Nitrogen metabolism
rn01100  Metabolic pathways
Other DBs
RHEA: 15652

KEGG   REACTION: R12623
Entry
R12623                      Reaction                               

Name
(Z)-2-methylureidoacrylate amidohydrolase
Definition
Methylureidoacrylate + H2O <=> Methylaminoacrylate + CO2 + Ammonia
Equation
Comment
two-step reaction (see R12624+R07316)
Reaction class
RC02737  C20255_C20256
Enzyme

KEGG   REACTION: R12624
Entry
R12624                      Reaction                               

Definition
Methylureidoacrylate + H2O <=> Methylaminoacrylate + Carbamate
Equation
Comment
the first step of two-step reaction (see R12623, R12624+R07316)
Reaction class
RC02737  C20255_C20256
Enzyme

KEGG   REACTION: R07316
Entry
R07316                      Reaction                               

Definition
Carbamate <=> Ammonia + CO2
Equation
Comment
spontaneous
the second step of two-step reaction (see R12625, R09980+R07316 or R12623, R12624+R07316 or R10079, R03546+R07316)
Enzyme
3.5.1.110       4.2.1.104
Pathway
rn00910  Nitrogen metabolism
rn01100  Metabolic pathways
Other DBs
RHEA: 15652

KEGG   REACTION: R10079
Entry
R10079                      Reaction                               

Name
carbamate hydro-lyase;
cyanate hydratase
Definition
Cyanate + HCO3- + H+ <=> Ammonia + 2 CO2
Equation
Comment
two-step reaction (see R03546+R07316)
bicarbonate is recycled (see R10092)
Reaction class
RC02807  C00011_C00288
Enzyme
Orthology
K01725  cyanate lyase [EC:4.2.1.104]

KEGG   REACTION: R03546
Entry
R03546                      Reaction                               

Name
carbamate hydro-lyase;
cyanate hydratase;
cyanate C-N-lyase
Definition
Cyanate + H+ + HCO3- <=> CO2 + Carbamate
Equation
Comment
first step of two-step reaction (see R10079, R03546+R07316)
bicarbonate is recycled (see R10092)
Reaction class
RC00952  C01417_C01563
RC02807  C00011_C00288
Enzyme
Pathway
rn00910  Nitrogen metabolism
rn01100  Metabolic pathways
Orthology
K01725  cyanate lyase [EC:4.2.1.104]
Reference
1  [PMID:3110153]
  Authors
Johnson WV, Anderson PM.
  Title
Bicarbonate is a recycling substrate for cyanase.
  Journal
J Biol Chem 262:9021-5 (1987)
Reference
2  [PMID:7947823]
  Authors
Anderson PM, Korte JJ, Holcomb TA.
  Title
Reaction of the N-terminal methionine residues in cyanase with diethylpyrocarbonate.
  Journal
Biochemistry 33:14121-5 (1994)
DOI:10.1021/bi00251a022
Other DBs
RHEA: 18492

KEGG   REACTION: R07316
Entry
R07316                      Reaction                               

Definition
Carbamate <=> Ammonia + CO2
Equation
Comment
spontaneous
the second step of two-step reaction (see R12625, R09980+R07316 or R12623, R12624+R07316 or R10079, R03546+R07316)
Enzyme
3.5.1.110       4.2.1.104
Pathway
rn00910  Nitrogen metabolism
rn01100  Metabolic pathways
Other DBs
RHEA: 15652

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