KEGG   Rattus norvegicus (rat): 100216475
Entry
100216475         CDS       T01003                                 

Gene name
Hexd
Definition
(RefSeq) hexosaminidase D
  KO
K14459  hexosaminidase [EC:3.2.1.52]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00511  Other glycan degradation
rno00513  Various types of N-glycan biosynthesis
rno01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00513 Various types of N-glycan biosynthesis
    100216475 (Hexd)
   00511 Other glycan degradation
    100216475 (Hexd)
Enzymes [BR:rno01000]
 3. Hydrolases
  3.2  Glycosylases
   3.2.1  Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
    3.2.1.52  beta-N-acetylhexosaminidase
     100216475 (Hexd)
SSDB
Motif
Pfam: Glyco_hydro_20
Other DBs
NCBI-GeneID: 100216475
NCBI-ProteinID: NP_001136034
RGD: 2302323
Ensembl: ENSRNOG00000036667
UniProt: B0BN37 F1LR76
Position
10
AA seq 486 aa
MTCSTPFKMRLVHLDLKGAPPKVSYLSEVFPLFHALGANGLLIEYEDMFPYEGHLRLLRA
KHAYSPSEVTEILRLARLSGLEVVPLVQTFGHMEFVLKHAAFAHLREVAPFPNTLNPHEA
ESLALVQAMIDQILELHRDVRWLHIGCDEVYYLGEGETSKQWLQQEQNSHAKLCLNHMQA
VASHVLTQHPGITPLVWDDMLRDIPQEQLKASGVPQLVEPVLWDYGADLDVHSKNFLIGK
YQECGFQRLWAASAFKGATGASQALPPVEHHIRNHELWLQVAGSGPVDTLQGIILTGWQR
YDHFSVLCELLPVGIPSLAACLQSLVHGGFAEDVRLRVERFLGVSSLEITDTVSEGAGSF
PGSDIHALVTQISLHLRSSVDSLLERNRYVTGWFSPYHRRRKLVHPVMIQHIQPEALSLL
SRWNNLVQQLEAALQPVFYPDAIEEWLEENVLPSMQRLQGLLQDLGEAAAQQPPPTSPGW
DTGQNP
NT seq 1461 nt   +upstreamnt  +downstreamnt
atgacatgttccacaccatttaagatgagattagttcatttggaccttaaaggagcacct
ccaaaggtttcatatctctctgaggtgtttcccctgttccatgcactcggtgcgaatggt
ctcctcattgagtatgaagacatgtttccctatgagggccacctgaggctgctgagagcc
aagcatgcatacagcccctcggaagttacagagatcctgcgcctggccagactcagtggg
ctggaagttgtccccttggtgcagacgtttggacacatggagtttgtgctaaagcatgcg
gcatttgctcatctccgtgaagtggctcccttccccaacaccctgaaccctcatgaggct
gagtccctggccttggtacaagctatgatcgaccaaattctggagctacacagggatgtc
cggtggctccacatcggctgtgatgaggtctactacctgggtgagggggagacctcaaaa
cagtggctacagcaggaacagaacagccatgcgaaactgtgcctgaaccacatgcaggcg
gtagccagccatgtgctgacccagcatcctggcataacacccttggtgtgggatgacatg
ctacgggacatccctcaggaacagctaaaagcgtctggggtgcctcaactggtggagcct
gtgctctgggactatggagctgacctggatgtccacagcaaaaatttcctcatagggaag
taccaggagtgtggcttccagaggttgtgggctgccagtgccttcaagggagccacaggg
gccagtcaggctctgccccctgttgagcaccacatcagaaaccatgagctgtggctgcag
gtggcaggcagtgggccagtggatactctacaaggaatcatcctgactggctggcagagg
tacgaccacttctctgtgctgtgtgagctgctccctgtgggaatcccatccctggctgcc
tgtctacagtcacttgtacatggaggctttgctgaggatgttaggctgcgagtggaacgc
ttccttggggtttcaagcctggaaataacggataccgtaagtgagggagctggctccttt
cctggcagtgacatccatgccctcgtcacacaaattagtctccacctgcgcagctctgtg
gattcacttctggagaggaacaggtatgtcactggctggttcagcccctaccatcgcagg
cggaagcttgttcatcctgttatgatccagcacatacagccggaggcactcagccttcta
agcaggtggaacaacctcgtgcagcagctggaggcagccctgcagccggtcttctacccg
gacgccattgaagagtggctggaggagaatgtgctccccagtatgcagcgactgcagggt
ctgctgcaggacctgggtgaggcggccgcccaacagccaccacccaccagcccgggctgg
gacacaggccagaacccctga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (3)   
Chemical substance (2)   
   KEGG COMPOUND (2)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (6)   
   UniProt (2)   
   RefSeq(pep) (4)   
DNA sequence (27)   
   RefSeq(nuc) (21)   
   GenBank (3)   
   EMBL (3)   
Protein domain (1)   
   Pfam (1)   
All databases (50)   

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KEGG   Rattus norvegicus (rat): 294673
Entry
294673            CDS       T01003                                 

Gene name
Hexb
Definition
(RefSeq) beta-hexosaminidase subunit beta precursor
  KO
K12373  hexosaminidase [EC:3.2.1.52]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00511  Other glycan degradation
rno00513  Various types of N-glycan biosynthesis
rno00520  Amino sugar and nucleotide sugar metabolism
rno00531  Glycosaminoglycan degradation
rno00603  Glycosphingolipid biosynthesis - globo and isoglobo series
rno00604  Glycosphingolipid biosynthesis - ganglio series
rno01100  Metabolic pathways
rno04142  Lysosome
Module
rno_M00079  Keratan sulfate degradation
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00520 Amino sugar and nucleotide sugar metabolism
    294673 (Hexb)
  09107 Glycan biosynthesis and metabolism
   00513 Various types of N-glycan biosynthesis
    294673 (Hexb)
   00531 Glycosaminoglycan degradation
    294673 (Hexb)
   00603 Glycosphingolipid biosynthesis - globo and isoglobo series
    294673 (Hexb)
   00604 Glycosphingolipid biosynthesis - ganglio series
    294673 (Hexb)
   00511 Other glycan degradation
    294673 (Hexb)
 09140 Cellular Processes
  09141 Transport and catabolism
   04142 Lysosome
    294673 (Hexb)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:rno03110]
    294673 (Hexb)
Enzymes [BR:rno01000]
 3. Hydrolases
  3.2  Glycosylases
   3.2.1  Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
    3.2.1.52  beta-N-acetylhexosaminidase
     294673 (Hexb)
Chaperones and folding catalysts [BR:rno03110]
 Intramolecular chaperones
  Others
   294673 (Hexb)
SSDB
Motif
Pfam: Glyco_hydro_20 Glycohydro_20b2 Glyco_hydro_20b
Other DBs
NCBI-GeneID: 294673
NCBI-ProteinID: NP_001011946
RGD: 1307607
Ensembl: ENSRNOG00000025274
UniProt: Q6AXR4
Position
2
AA seq 537 aa
MPGSPRRAPGLLLQALVAMVSLALVAPFGLQPALWPMPRSVQVFPRLLYISPENFQIDNS
PNSTAGPSCSLLLEAFRRYYNYIFGFYKRHHGPAKFQDKPQLEKLLVFINLEPQCDAFPS
MSSDESYSLLVQEPVALLKANEVWGALRGLETFSQLVYQDAYGTFTINESTIADSPRFPH
RGILIDTSRHYLPVKTIFKTLDAMAFNKFNVLHWHIVDDQSFPYQSITFPELSNKGSYSL
SHVYTPNDIHMVLEYARLRGIRVIPEFDSPGHTQSWGKGQKNLLTPCFIQKIRTQKVGPV
DPSLNTTYVFFDTFFKEISRVFPDQFIHLGGDEVEFECWASNPNIQNFMKKKGFGNNFRR
LESFYIKKILDIITSLKKSSIVWQDVFDDQVELQPGTVVEVWKSENYLNELAQVTASGFP
AILSAPWYLDLISYGQDWRNYYKAEPLNFEGSEKQKQLVIGGEACLWGEYVDATNLIPRL
WPRASAVGERLWSPRIITNLENAYRRLAVHRCRMVSRGIAAQPLFTGYCNYENKMEK
NT seq 1614 nt   +upstreamnt  +downstreamnt
atgccggggtccccgcgtcgcgccccggggctgctgctgcaggcgctggtggcgatggtg
tcgctggccctggtggcccccttcgggctgcaacccgcgctgtggcccatgccgcgctcg
gtgcaggtgttcccgcggctgctgtacatctccccggagaacttccagatcgacaacagc
cccaattccaccgcgggcccctcctgctcgctgctgctggaggcgtttcggcgatattac
aactatatttttggtttctacaagagacatcatggccctgctaaatttcaagataaacca
cagttagagaagcttctggtcttcattaacctcgaaccgcagtgtgatgccttccctagt
atgtcatcagatgagtcctattctctacttgtacaagaaccagtagctctcctcaaggcc
aacgaagtttggggagcactaagaggtttggagacctttagccagttggtttaccaggac
gcttatgggacttttaccatcaatgaatccactattgctgattctccaagattccctcat
agaggaattctaattgatacatccagacactacctgcctgtgaagacaatttttaaaact
ctggatgccatggcttttaataagtttaacgtccttcactggcacatagtggacgaccag
tctttcccttatcagagtatcacttttcctgagctaagcaacaagggaagctattctttg
tctcatgtctatacaccaaacgacatccatatggtacttgaatatgcccggctccgaggg
attcgagtcataccagaattcgatagccccggccatacacagtcttgggggaaaggtcag
aaaaaccttctaactccatgtttcattcaaaaaattagaactcaaaaggttggacctgta
gacccaagtctaaatacaacatacgtattctttgacacattcttcaaagaaatcagcagg
gtgtttccagaccagtttatccacttgggaggagatgaagtggaatttgaatgttgggca
tcaaacccaaacatccaaaatttcatgaagaaaaagggctttggcaacaattttagaaga
ctagaatccttttatatcaaaaagattttggatattatcacatccttaaagaagagctcc
attgtttggcaagacgtttttgatgatcaagtggagcttcagccgggcacggtagttgaa
gtgtggaaaagtgaaaattacttaaatgaattagcacaagtcacagcatccggcttccct
gccatcctttctgctccttggtacttagacctgatcagctacgggcaagactggagaaac
tactataaagcggagccccttaactttgaaggttcggagaagcagaaacaacttgttatt
ggtggagaggcttgcctatggggagaatatgtggatgcaactaaccttattccaagacta
tggcctcgggcaagcgctgttggtgagaggctctggagccctagaattatcaccaacctg
gaaaacgcctacagacgactggcagtgcaccgctgtagaatggtcagccgcggaatagct
gcacaacctctctttactggatattgtaactacgagaataaaatggaaaagtga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (9)   
   KEGG PATHWAY (8)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (7)   
   KEGG ENZYME (1)   
   KEGG REACTION (6)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (5)   
   RefSeq(nuc) (1)   
   GenBank (2)   
   EMBL (2)   
Protein domain (3)   
   Pfam (3)   
All databases (42)   

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KEGG   Rattus norvegicus (rat): 300757
Entry
300757            CDS       T01003                                 

Gene name
Hexa
Definition
(RefSeq) beta-hexosaminidase subunit alpha precursor
  KO
K12373  hexosaminidase [EC:3.2.1.52]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00511  Other glycan degradation
rno00513  Various types of N-glycan biosynthesis
rno00520  Amino sugar and nucleotide sugar metabolism
rno00531  Glycosaminoglycan degradation
rno00603  Glycosphingolipid biosynthesis - globo and isoglobo series
rno00604  Glycosphingolipid biosynthesis - ganglio series
rno01100  Metabolic pathways
rno04142  Lysosome
Module
rno_M00079  Keratan sulfate degradation
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00520 Amino sugar and nucleotide sugar metabolism
    300757 (Hexa)
  09107 Glycan biosynthesis and metabolism
   00513 Various types of N-glycan biosynthesis
    300757 (Hexa)
   00531 Glycosaminoglycan degradation
    300757 (Hexa)
   00603 Glycosphingolipid biosynthesis - globo and isoglobo series
    300757 (Hexa)
   00604 Glycosphingolipid biosynthesis - ganglio series
    300757 (Hexa)
   00511 Other glycan degradation
    300757 (Hexa)
 09140 Cellular Processes
  09141 Transport and catabolism
   04142 Lysosome
    300757 (Hexa)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:rno03110]
    300757 (Hexa)
Enzymes [BR:rno01000]
 3. Hydrolases
  3.2  Glycosylases
   3.2.1  Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
    3.2.1.52  beta-N-acetylhexosaminidase
     300757 (Hexa)
Chaperones and folding catalysts [BR:rno03110]
 Intramolecular chaperones
  Others
   300757 (Hexa)
SSDB
Motif
Pfam: Glyco_hydro_20 Glycohydro_20b2 Glyco_hydro_20b B_solenoid_dext
Other DBs
NCBI-GeneID: 300757
NCBI-ProteinID: NP_001004443
RGD: 2792
Ensembl: ENSRNOG00000010252
UniProt: Q641X3
Position
8
AA seq 528 aa
MAGCRLWVSLLLAAALACLATALWPWPQYIQTSHRRYTLYPNNFQFRYHAGSAAQAGCVV
LDEAFRRYRSLLFGSGSWPRPSFSKKQQPLGKNILMVSVVTAECNEFPNLESVENYTLTI
NDDQCLLSSETVWGALRGLETFSQLVWKSAEGTFFINKTKITDFPRFPHRGILLDTSRHY
LPLSSILNTLDVMAYNKFNVFHWHLVDDSSFPYESFTFPELTRKGSFNPVTHIYTAQDVK
EVIEYARLRGIRVLAEFDTPGHTLSWGAGVPGLLTPCYSGSRLSGTYGPVNPSLNSTYDF
MSTFFLEISSVFPDFYLHLGGDEVDFTCWKSNPNIQAFMKKKGFTDYKQLESFYIQTLLD
IVSDYDKGYVVWQEVFDNKVKVRPDTIIQVWREEMPVQYMKEIEAITQAGFRALLSAPWY
LNRVKYGPDWKEMYKVEPLAFRGTPAQKALVIGGEACMWGEYVDSTNLVPRLWPRAGAIA
ERLWSSNLTTNMDFAFKRLSHFRCELLRRGIQAQPISVGYCEQEFEHT
NT seq 1587 nt   +upstreamnt  +downstreamnt
atggccggctgcaggctctgggtttcgctgctgctggcggcggcgttggcttgcttggcc
acggcgctgtggccctggccccagtacatccaaacctcccaccggcgctacaccctgtac
cccaacaacttccagttccggtaccatgccggttcggccgcgcaggcgggctgcgttgtc
ctcgacgaggcctttcgacgctaccgtagcctgctcttcggttccggctcttggccccga
cccagcttctcaaaaaaacagcagccgttggggaagaacattctgatggtctctgtcgtc
acagccgaatgtaatgagtttcctaatttggagtccgtagaaaattacaccctaaccatt
aatgatgaccagtgtttactctcctctgagactgtctggggcgctctgcgaggtctggag
actttcagtcagcttgtttggaagtcagctgagggcacgttctttatcaacaagacaaag
attacagactttcctcgattccctcaccggggcatactgctggatacatctcgccattac
ctgccgttatctagcatcctgaacacactggatgtcatggcgtacaataaattcaacgtg
ttccactggcacttggtggacgactcttccttcccatacgagagcttcaccttcccagag
ctcaccagaaaggggtccttcaaccctgttacccacatctacacagcacaggatgtgaag
gaggtcattgaatatgcaaggcttcggggtatccgagtgctggccgaatttgacactcct
ggccacactttgtcctggggggcaggtgtccctggattattaacaccttgctactctggg
tcccgtctctctggcacctatggacctgtgaaccccagcctcaacagcacctacgacttc
atgagcacattcttcctggagatcagctctgtcttccctgacttttatctccacctggga
ggagatgaagttgacttcacctgctggaagtccaaccccaacatccaggccttcatgaag
aaaaagggctttactgactacaagcagctggagtcattctacatccagacgctgctggac
atcgtctctgattatgacaagggctatgtggtgtggcaggaagtatttgataataaagtg
aaggttcggccagacacaatcatacaggtgtggcgggaagagatgccggtccagtacatg
aaggagatagaggccatcacccaggctggcttccgggccctgctgtctgctccctggtac
ctgaaccgggtgaagtatggccctgactggaaggaaatgtacaaagtggagcccctggca
tttcgtggtacacctgcacaaaaggctctggtcattggaggggaagcctgtatgtgggga
gagtatgtggacagcacaaaccttgtccccaggctctggcccagagcaggtgccattgcc
gaaagactgtggagcagtaacctgacgactaatatggactttgcctttaaacgtctgtcc
catttccgctgtgagctgctgaggagaggaatccaggcccagcccatcagcgtgggctac
tgtgagcaggagtttgagcatacttga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (9)   
   KEGG PATHWAY (8)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (7)   
   KEGG ENZYME (1)   
   KEGG REACTION (6)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (5)   
   RefSeq(nuc) (3)   
   GenBank (1)   
   EMBL (1)   
Protein domain (4)   
   Pfam (4)   
All databases (44)   

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