KEGG   Rattus norvegicus (rat): 112400
Entry
112400            CDS       T01003                                 
Symbol
Nrg1
Name
(RefSeq) pro-neuregulin-1, membrane-bound isoform isoform 1
  KO
K05455  neuregulin 1
Organism
rno  Rattus norvegicus (rat)
Pathway
rno01521  EGFR tyrosine kinase inhibitor resistance
rno04012  ErbB signaling pathway
rno05014  Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    112400 (Nrg1)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    112400 (Nrg1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    112400 (Nrg1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:rno04052]
    112400 (Nrg1)
   00536 Glycosaminoglycan binding proteins [BR:rno00536]
    112400 (Nrg1)
Cytokines and neuropeptides [BR:rno04052]
 Cytokines
  Growth factors (RTK binding)
   112400 (Nrg1)
Glycosaminoglycan binding proteins [BR:rno00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   112400 (Nrg1)
SSDB
Motif
Pfam: Neuregulin EGF DUF6377 Cyt_b-c1_8 DUF973
Other DBs
NCBI-GeneID: 112400
NCBI-ProteinID: NP_001258047
RGD: 621341
Ensembl: ENSRNOG00000010392
UniProt: A0A0G2K3Q3 A6IVV2
Position
16:65954084..67007484
AA seq 700 aa
MEIYSPDMSEVAGGRSSSPSTQLSAAPSLDGLPAAEEHIPDTHTEDERSPGLLGLAVPCC
VCLEAERLRGCLNSEKICIVPILACLVSLCLCIAGLKWVFVDKIFEYDSPTHLDPGGLGQ
DPVISLDPTAAPAILVSSEAYTSPVSKAQSEAGAHVTVQGDHAAVASEPSAVPTRKNRLS
AFPPFHSTAPPFPSPARTPEVRTPKSGTQPQTTETNLQTAPKLSTSTSTTGTSHLIKCAE
KEKTFCVNGGECFTVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYKHLGIEFMEAEELY
QKRVLTITGICIALLVVGIMCVVAYCKTKKQRQKLHDRLRQSLRSERSNLVNIANGPHHP
NPPPENVQLVNQYVSKNVISSEHIVEREVETSFSTSHYTSTAHHSTTVTQTPSHSWSNGH
TESIISESNSVIMMSSVENSRHSSPAGGPRGRLHGLGGPRDNSFLRHARETPDSYRDSPH
SERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSVAVSPFVEEERPLLL
VTPPRLREKKYDHHPQQLNSFHHNPAHQSTSLPPSPLRIVEDEEYETTQEYESVQEPVKK
VTNSRRAKRTKPNGHIANRLEMDSNTSSVSSNSESETEDERVGEDTPFLGIQNPLAASLE
VAPAFRLAESRTNPAGRFSTQEELQARLSSVIANQDPIAV
NT seq 2103 nt   +upstreamnt  +downstreamnt
atggagatttattccccagacatgtctgaggtagctggcgggaggtcctccagcccctcc
actcagctgagtgcagccccatctcttgatgggcttccggcagcggaggaacatatacca
gacacccacacagaagatgagagaagccctggactcctgggcctggcggtgccctgctgt
gtgtgcctggaagctgagcgcctgagagggtgtctcaactccgagaagatctgcattgtt
cccattctggcttgcctagtcagcctctgcctctgcattgctggcctgaagtgggtattt
gtggacaagatatttgaatacgactctcctacccaccttgaccctggggggttaggccag
gaccctgtgatttctctggatccaactgctgccccagccattttggtatcatctgaggca
tacacttcacctgtctctaaggctcagtctgaagctggggctcatgttacagtacaaggt
gaccatgctgctgtggcctctgaaccttcagcagtaccgacccggaagaaccggctgtct
gcttttcctccctttcactctactgcaccgcccttcccttctccagctcggacccctgag
gtgagaacacccaagtcaggaactcagccacaaacaacagaaactaacctgcaaactgct
cctaaactttccacatcgacatccacgactgggaccagccatctcataaagtgcgcggag
aaggagaaaactttctgtgtgaatgggggcgagtgcttcacggtgaaggacctgtcaaac
ccgtcaagatacttgtgcaagtgcccaaatgagtttactggtgatcgttgccaaaactac
gtaatggccagcttctacaagcatcttgggattgaatttatggaagcggaggaactctac
cagaagagggtgctgacaattactggcatctgtatcgccctgctggtggtcggcatcatg
tgtgtggtggcctactgcaaaaccaagaagcagcggcagaagcttcatgatcggcttcgg
cagagtcttcggtcagaacggagcaacctggtgaacatagcgaatgggcctcaccaccca
aacccaccgccagagaacgtgcagctggtgaatcaatacgtatctaaaaacgtcatctcc
agtgagcatattgttgagagagaagtggagacttccttttccaccagtcattacacttcc
acagcccatcactccacgactgtcacccagactcctagtcacagctggagtaatgggcac
acggagagcatcatttcagaaagcaactccgtaatcatgatgtcttcggtagagaacagc
aggcacagcagtcccgccgggggcccacgaggacgtcttcatggcctgggaggccctcgt
gataacagcttcctcaggcatgccagagaaacccctgactcctacagagactctcctcat
agcgaaaggtatgtatcagccatgaccaccccggctcgtatgtcacctgtagatttccac
acgccaagctcccctaaatcgcccccttcggaaatgtctccacccgtgtccagcatgacg
gtgtcaatgccctctgtggcagtcagcccctttgtggaagaagagaggcctctgctgctt
gtgacgccaccaaggctacgggagaagaaatatgatcatcacccccagcaactcaactcc
tttcatcacaaccctgcacatcagagtaccagcctcccccctagcccactgaggatagtg
gaggatgaggagtacgagacgacccaggagtatgagtcagttcaagagcccgttaagaaa
gtcaccaatagccggcgggccaaaagaaccaagcccaatggccacattgccaataggttg
gaaatggacagcaacacaagttctgtgagcagtaactcagaaagtgagacagaagacgaa
agagtaggtgaagacacaccattcctgggcatacagaaccccctggcagccagccttgag
gtggcccctgccttccgtctggctgagagcaggactaacccagcaggccgcttctccaca
caggaggaattacaggccaggctgtctagtgtaatcgctaaccaagaccctattgctgta
taa

  All links  
Gene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (24)   
   UniProt (2)   
   RefSeq(pep) (22)   
DNA sequence (82)   
   RefSeq(nuc) (22)   
   GenBank (30)   
   EMBL (30)   
Protein domain (5)   
   Pfam (5)   
All databases (116)   

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