KEGG   Rattus norvegicus (rat): 114517Help
Entry
114517            CDS       T01003                                 

Gene name
Itga6
Definition
(RefSeq) integrin subunit alpha 6
  KO
K06485  integrin alpha 6
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04151  PI3K-Akt signaling pathway
rno04510  Focal adhesion
rno04512  ECM-receptor interaction
rno04514  Cell adhesion molecules (CAMs)
rno04640  Hematopoietic cell lineage
rno04810  Regulation of actin cytoskeleton
rno05145  Toxoplasmosis
rno05165  Human papillomavirus infection
rno05200  Pathways in cancer
rno05222  Small cell lung cancer
rno05410  Hypertrophic cardiomyopathy (HCM)
rno05412  Arrhythmogenic right ventricular cardiomyopathy (ARVC)
rno05414  Dilated cardiomyopathy (DCM)
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    114517 (Itga6)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    114517 (Itga6)
   04514 Cell adhesion molecules (CAMs)
    114517 (Itga6)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    114517 (Itga6)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    114517 (Itga6)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    114517 (Itga6)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    114517 (Itga6)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    114517 (Itga6)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy (HCM)
    114517 (Itga6)
   05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
    114517 (Itga6)
   05414 Dilated cardiomyopathy (DCM)
    114517 (Itga6)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    114517 (Itga6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    114517 (Itga6)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:rno04147]
    114517 (Itga6)
   04515 Cell adhesion molecules [BR:rno04515]
    114517 (Itga6)
   04090 CD molecules [BR:rno04090]
    114517 (Itga6)
Exosome [BR:rno04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   114517 (Itga6)
  Exosomal proteins of breast milk
   114517 (Itga6)
Cell adhesion molecules [BR:rno04515]
 Integrins
  Integrin alpha subunits
   114517 (Itga6)
CD molecules [BR:rno04090]
 Proteins
  114517 (Itga6)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Integrin_alpha2 FG-GAP VCBS Integrin_alpha PAG LRR19-TM DUF4381
Motif
Other DBs
NCBI-GeneID: 114517
NCBI-ProteinID: NP_446177
RGD: 621633
Ensembl: ENSRNOG00000001518
UniProt: Q924W3 Q924W2
Position
3q23
AA seq 1073 aa AA seqDB search
MAVAGQLCLLYLSAGLLARLSTAFNLDTREDNVIRKSGDPGSLFGFSLAMHWQLQPEDKR
LLLVGAPRAEALPLQKANRTGGLYSCDITSRGPCTRIVFDNDADPMSESKEDQWMGVTVQ
SQGPGGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMDGGDWSFCDGRLR
GHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVG
GETDHDESLVPVPANSYLGFSLDSGKGIVSKDDITFVSGAPRANHSGAVVLLKRDMKSAH
LLLEYIFDGEGLASSFGYDVAVVDLNADGWQDIVIGAPQYFDRDGEVGGAVYVYINQQGR
WSNVKPVRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGKVFIYHGSPTGIITK
PTQVLEGTTPFFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINILKTITVTPSR
IDLRQKSMCGSPSGICLKVKACFEYTAKPSGYNPPISILGILEAEKERRKSGLSSRVQFR
NQGSEPKYTQELTLNRQKQRACMEETLWLQENIRDKLRPIPITASVEIQEPSSRRRVNSL
PEVLPILNSNEAKTVQTDVHFLKEGCGDDNVCNSNLKLEYKFGTREGNQDKFSYLPIQKG
IPELVLKDQKDIALKITVTNGPSDPRNPRKDGDDAHEAKLIATFPDTLTYSAYRELRAFP
EKQLSCVANQNGSQADCELGNPFKRNSSVTFYLILSTTEVTFDTTDLDINLKLETTSNQD
NLAPITAKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKSEEEVGSLIEYEFRVINLG
KPLKNLGTATLNIQWPKEISNGKWLLYLMKVESKGLEQVVCEPHNEINFLKLKESHNSRK
KRELPEKQIDDSRKFSLFSERKYQTLNCSVNVRCVNIRCPLRGLDSKASLVLRSRLWNST
FLEEYSKLNYLDILVRASIDVTAAAQNIKLPHAGTQVRVTVFPSKTVAQYSGIAWWIILL
AVLAGILMLALLVFLLWKCGFFKRNKKDHYDATYHKAEIHTQPSDKERLTSDA
NT seq 3222 nt NT seq  +upstreamnt  +downstreamnt
atggcggtcgccggccagttgtgcttgctctacctgtccgcagggcttctggcccggctg
agcacagctttcaacctggatacccgcgaggacaacgtgatccggaaatcgggggatccc
gggagcctcttcggcttctcgctcgccatgcactggcagttgcagccggaggacaagcgg
ctgttgcttgtgggggcacctcgggcagaagcacttcccctgcagaaggcgaacagaaca
gggggcctgtacagctgtgacatcacctcccggggaccttgcacacgaattgtatttgat
aatgatgctgatcctatgtcagaaagcaaggaagaccagtggatgggagtcactgtccag
agtcaaggtccagggggcaaagtggtgacgtgtgcgcatcgatacgagaaacggcagcac
gttaacacgaagcaggagtcccgggacatcttcggaaggtgttacgtcctgagtcagaat
ctcagaattgaagatgatatggatggaggagactggagtttctgtgatggccgattgagg
ggccatgaaaaatttggctcttgtcagcaaggagtagcggctactttcactaaagacttt
cattacattgtttttggagccccagggacttacaactggaaagggatcgttcgtgtagaa
caaaagaataacactttttttgacatgaacatctttgaagatgggccctatgaagttggt
ggagagactgatcatgacgaaagtctcgtgcccgttcctgctaacagttatctaggcttt
tctctggactcagggaagggtattgtttctaaagatgacatcacttttgtatctggtgct
ccaagagccaatcacagtggggctgtagttttgctaaaaagagacatgaagtcagcacat
cttctccttgagtatatatttgatggtgaaggcctggcttcttcgtttggctatgacgtg
gcggtggtggacctcaatgcagatgggtggcaagacatcgttatcggagcgccacagtac
tttgacagggatggcgaagtcgggggtgcggtgtacgtctacattaaccagcaaggcaga
tggagtaatgtgaagccagttcgtctaaatgggaccaaagactcgatgtttggaatcgca
gtgaaaaatatcggcgatattaatcaagatggctatccggatattgctgttggagctccc
tatgacgatctggggaaggtttttatctatcatggatccccgactggcataattaccaag
ccaacacaggttcttgagggtacaacgcctttcttcggctactcaatcgctgggaacatg
gacctggacaggaattcctaccctgacgttgctgtgggttccctctcagactcagtaact
attttcagatcccggccagtgattaacattctgaaaaccatcacagtgactcctagcaga
attgacctccgccagaaatccatgtgtgggtcacctagcgggatatgcctcaaggttaaa
gcctgttttgaatatactgcgaagccctccggttataaccctccaatatcaattttgggt
attcttgaagctgaaaaagaaagaagaaagtcagggttgtcgtcaagagttcagtttcga
aaccaaggttctgagccaaagtatactcaggagctgaccctgaacaggcagaagcagcgg
gcatgcatggaggagacgctctggctgcaggaaaacatcagagacaagctgcgccccatc
cccatcacggcttctgtggagatccaggagcccagctctcgacggcgggtgaattcactt
ccagaagttcttcccatcttgaattcaaatgaagccaaaacagtgcagacagatgtccac
ttcttaaaggaaggatgtggagacgacaatgtctgtaacagcaaccttaagctagagtat
aaatttggtacccgagaaggaaatcaagacaaattctcttaccttccaattcagaaaggc
atcccagaattagtcctaaaagatcagaaagatatagctctgaaaataacggtgaccaac
ggcccttctgatccaaggaatccccggaaagatggtgacgatgcccacgaagccaaactc
atcgcaacgtttccagacaccctgacatattccgcctacagagagctgagggctttccct
gagaagcagctgagctgtgttgccaaccagaatggctcccaagctgactgtgagctcgga
aatcctttcaagagaaattccagtgttactttttatctgattttaagtaccaccgaggtc
acctttgacaccacagatctggatattaacctgaagttggaaacaacaagcaatcaggat
aatttggctccaattacagcgaaagcaaaagtggttattgaattgcttttatcggtctct
ggagtcgctaaaccttcgcaggtgtattttggaggtacagttgttggtgagcaggccatg
aagtctgaagaagaagtaggaagtttaatagagtatgaattcagggtgattaacttgggt
aaacctcttaaaaacctcggcacggcaaccctgaatatccagtggcccaaggagattagc
aatggcaaatggttgctttatttgatgaaggtcgaatccaaaggtttggagcaggttgtc
tgtgagccacacaatgaaataaacttcctcaagctgaaggagtctcacaactcaagaaag
aagcgggaacttcctgaaaaacagatagacgacagcaggaagttttctctattttccgaa
agaaaataccagaccctcaactgcagcgtcaacgtgaggtgtgtgaacatcaggtgtcca
ctgcgagggctggacagcaaggcctctctcgttctacgctccaggctgtggaacagcacg
tttctagaggaatattccaaactgaactacttggacatcctcgtgagggcgtccatagat
gtgaccgccgccgctcagaatatcaagctccctcatgcgggcactcaggttcgagtgacg
gtgtttccctcaaagacggtagctcagtattcagggatagcgtggtggatcatcctcctg
gctgtgcttgccgggattttgatgctggctctattagtgtttttactgtggaagtgtggt
ttcttcaagagaaataagaaagatcattacgatgccacctaccacaaggctgagatccac
actcagccgtctgataaagagaggcttacttccgatgcatag

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