KEGG   Rattus norvegicus (rat): 114711
Entry
114711            CDS       T01003                                 
Symbol
Gne
Name
(RefSeq) bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase
  KO
K12409  bifunctional UDP-N-acetylglucosamine 2-epimerase / N-acetylmannosamine kinase [EC:3.2.1.183 2.7.1.60]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00520  Amino sugar and nucleotide sugar metabolism
rno00541  Biosynthesis of various nucleotide sugars
rno01100  Metabolic pathways
rno01250  Biosynthesis of nucleotide sugars
Module
rno_M00955  CMP-Neu5Ac/Neu5Gc biosynthesis, animals, UDP-GlcNAc => CMP-Neu5Ac => CMP-Neu5Gc
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00520 Amino sugar and nucleotide sugar metabolism
    114711 (Gne)
   00541 Biosynthesis of various nucleotide sugars
    114711 (Gne)
Enzymes [BR:rno01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.60  N-acylmannosamine kinase
     114711 (Gne)
 3. Hydrolases
  3.2  Glycosylases
   3.2.1  Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
    3.2.1.183  UDP-N-acetylglucosamine 2-epimerase (hydrolysing)
     114711 (Gne)
SSDB
Motif
Pfam: Epimerase_2 ROK Hexokinase_1 DRTGG FGGY_N Glucokinase
Other DBs
NCBI-GeneID: 114711
NCBI-ProteinID: NP_446217
RGD: 69239
Ensembl: ENSRNOG00000014365
UniProt: O35826 A6IJ68
Position
5:complement(63062953..63103320)
AA seq 722 aa
MEKNGNNRKLRVCVATCNRADYSKLAPIMFGIKTEPAFFELDVVVLGSHLIDDYGNTYRM
IEQDDFDINTRLHTIVRGEDEAAMVESVGLALVKLPDVLNRLKPDIMIVHGDRFDALALA
TSAALMNIRILHIEGGEVSGTIDDSIRHAITKLAHYHVCCTRSAEQHLISMCEDHDRILL
AGCPSYDKLLSAKNKDYMSIIRMWLGDDVKCKDYIVALQHPVTTDIKHSIKMFELTLDAL
ISFNKRTLVLFPNIDAGSKEMVRVMRKKGIEHHPNFRAVKHVPFDQFIQLVAHAGCMIGN
SSCGVREVGAFGTPVINLGTRQIGRETGENVLHVRDADTQDKILQALHLQFGKQYPCSKI
YGDGNAVPRILKFLKSIDLQEPLQKKFCFPPVKENISQDIDHILETLSALAVDLGGTNLR
VAIVSMKGEIVKKYTQFNPKTYEERISLILQMCVEAAAEAVKLNCRILGVGISTGGRVNP
QEGVVLHSTKLIQEWNSVDLRTPLSDTLHLPVWVDNDGNCAAMAERKFGQGKGQENFVTL
ITGTGIGGGIIHQHELIHGSSFCAAELGHLVVSLDGPDCSCGSHGCIEAYASGMALQREA
KKLHDEDLLLVEGMSVPKDEAVGALHLIQAAKLGNVKAQSILRTAGTALGLGVVNILHTM
NPSLVILSGVLASHYIHIVRDVIRQQALSSVQDVDVVVSDLVDPALLGAASMVLDYTTRR
IH
NT seq 2169 nt   +upstreamnt  +downstreamnt
atggagaagaacgggaataaccggaagcttcgggtttgcgttgccacctgcaaccgagcc
gattactccaaactggcccccatcatgttcggcattaagacggagcctgcgttcttcgag
ctcgacgtggtggtgctgggctctcacctgatcgacgactacggaaacacataccgcatg
attgagcaggacgactttgacatcaacaccaggctacacacgattgttagaggggaagac
gaagcagccatggtagagtcagtgggcctagcgctagtgaagctaccggatgtcctcaac
cgcctgaagcctgacatcatgattgttcacggagaccgatttgacgccctcgctctggct
acatctgctgccctgatgaacatccgcatccttcacattgaaggaggagaggtcagtggg
actattgatgactctatcagacacgccataacaaaactggctcactaccacgtgtgctgc
accaggagtgcagagcaacacctgatctccatgtgtgaggaccacgaccgcatccttttg
gccggctgcccttcctatgacaaactgctctcagccaagaataaagactatatgagcatc
attcggatgtggctaggtgatgatgtaaaatgtaaagattacattgttgccctgcaacac
ccggtgaccaccgacattaagcattccataaagatgttcgaactgacactggatgctctt
atctcatttaacaagaggaccctagttctgtttccaaatatcgatgcaggcagcaaggag
atggttcgagtgatgcggaagaagggcatcgagcatcaccccaatttccgcgcagtcaag
cacgtcccgtttgaccagttcattcagctggtcgcccacgctggctgcatgattgggaat
agcagctgtggagtgcgtgaggttggcgcctttggaacccctgtgatcaacctgggcacg
cggcagataggaagagaaacgggggagaatgttcttcatgtccgggatgctgacacccaa
gacaaaatattacaagcactacacctccagttcggtaaacagtacccttgctcaaagata
tatggggatggaaatgctgttccaaggattttaaagtttctcaaatccatcgaccttcaa
gagccactacagaagaaattctgcttccctcccgtgaaggagaacatctctcaggatatt
gaccatatcctcgaaactctgagtgccttggctgttgatctcggggggacgaatctgaga
gtggcgatagttagcatgaagggtgaaatagttaagaagtacacccagttcaatcctaaa
acctatgaggaaaggattagtctaatcctgcagatgtgtgtggaagcggcagcagaagcc
gtgaagctcaattgcagaattctgggagtaggcatctccacaggtggccgtgtgaatccc
caggaaggagttgtgctgcactcgaccaagctgatacaggagtggaactctgtggacctc
aggacaccactctccgacaccctgcatctccccgtgtgggtggacaacgacggcaactgc
gctgccatggcggagaggaagtttggccaaggaaaaggacaggagaactttgtgacgctc
atcacagggacagggatcggtgggggaatcatccaccagcacgagctgatccacggcagc
tccttctgtgcggcagagcttggccacctcgtggtgtctctggatggtcctgactgctcc
tgtggaagccatgggtgcattgaagcctacgcctctggaatggccttgcagagggaagca
aagaagctccacgacgaggacctgctcttggtggaagggatgtcagtgccaaaagacgaa
gctgtgggcgccctccatctcatccaagccgccaagctgggcaacgtgaaggcccagagc
atcttacggacagctggaactgctttgggactcggagttgtgaatatcctccacactatg
aatccttccctggtgatcctgtctggagtcctggctagtcactacatccacattgtgagg
gacgtcatccgccagcaagccctgtcctccgtgcaggatgtggatgtagtggtttcagac
ttggttgacccggccctgcttggtgcggccagcatggttctggactacacgacccgcagg
atccactag

  All links  
Gene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (10)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (7)   
DNA sequence (13)   
   RefSeq(nuc) (7)   
   GenBank (3)   
   EMBL (3)   
Protein domain (6)   
   Pfam (6)   
All databases (34)   

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