KEGG   Rattus norvegicus (rat): 114862
Entry
114862            CDS       T01003                                 

Gene name
Cacna1h
Definition
(RefSeq) voltage-dependent T-type calcium channel subunit alpha-1H
  KO
K04855  voltage-dependent calcium channel T type alpha-1H
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04010  MAPK signaling pathway
rno04020  Calcium signaling pathway
rno04713  Circadian entrainment
rno04925  Aldosterone synthesis and secretion
rno04927  Cortisol synthesis and secretion
rno04929  GnRH secretion
rno04934  Cushing syndrome
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    114862 (Cacna1h)
   04020 Calcium signaling pathway
    114862 (Cacna1h)
 09150 Organismal Systems
  09152 Endocrine system
   04929 GnRH secretion
    114862 (Cacna1h)
   04925 Aldosterone synthesis and secretion
    114862 (Cacna1h)
   04927 Cortisol synthesis and secretion
    114862 (Cacna1h)
  09159 Environmental adaptation
   04713 Circadian entrainment
    114862 (Cacna1h)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    114862 (Cacna1h)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:rno04040]
    114862 (Cacna1h)
Ion channels [BR:rno04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   114862 (Cacna1h)
SSDB
Motif
Pfam: Ion_trans PKD_channel
Other DBs
NCBI-GeneID: 114862
NCBI-ProteinID: NP_722521
RGD: 68943
Ensembl: ENSRNOG00000033893
UniProt: Q9EQ60
Position
10
AA seq 2359 aa
MTEGTLAADEVRVPLGASPPAPAAPVRASPASPGAPGREEQGGSGSGVLAPESPGTECGA
DLGADEEQPVPYPALAATVFFCLGQTTRPRSWCLRLVCNPWFEHISMLVIMLNCVTLGMF
RPCEDVECRSERCSILEAFDDFIFAFFAVEMVIKMVALGLFGQKCYLGDTWNRLDFFIVM
AGMMEYSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFV
FFIFGIVGVQLWAGLLRNRCFLDSAFVRNNNLTFLRPYYQTEEGEENPFICSSRRDNGMQ
KCSHIPSRRELRVQCTLGWEAYGQPQAEDGGAGRNACINWNQYYNVCRSGEFNPHNGAIN
FDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIMGSFFMINLCLVVIAT
QFSETKQRENQLMREQRARYLSNDSTLASFSEPGSCYEELLKYVGHIFRKVKRRSLRLYA
RWQSRWRKKVDPSSTVHGQGPGRRPRRAGRRTASVHHLVYHHHHHHHHHYHFSHGGPRRP
SPEPGAGDNRLVRACAPPSPPSPGHGPPDSESVHSIYHADCHVEGPQERARVAHSIATAA
SLKLASGLGTMNYPTILPSGTVNSKGGTSSRPKGLRGAGAPGAAVHSPLSLGSPRPYEKI
QDVVGEQGLGRASSHLSGLSVPCPLPSPQAGTLTCELKSCPYCASALEDPEFEFSGSESG
DSDAHGVYEFTQDVRHGDCRDPVQQPHEVGTPGHSNERRRTPLRKASQPGGIGHLWASFS
GKLRRIVDSKYFNRGIMAAILVNTLSMGVEYHEQPEELTNALEISNIVFTSMFALEMLLK
LLACGPLGYIRNPYNIFDGIVVVISVWEIVGQANGGLSVLRTFRLLRVLKLVRFLPALRR
QLVVLMRTMDNVATFCMLLMLFIFIFSILGMHLFGCKFSLKTDSGDTVPDRKNFDSLLWA
IVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQAEGD
ATRSDTDEDKTSTQLEGDFDKLRDLRATEMKMYSLAVTPNGHLEGRGSLPPPLITHTAAT
PMPTPKSSPNLDVAHALLDSRRSSSGSVDPQLGDQKSLASLRSSPCTPWGPNSAGSSRRS
SWNSLGRAPSLKRRNQCGERESLLSGEGKGSTDDEAEDSRPSTGTHPGASPGPRATPLRR
AESLDHRSTLDLCPPRPAALLPTKFHDCNGQMVALPSEFFLRIDSHKEDAAEFDDDIEDS
CCFRLHKVLEPYAPQWCRSRESWALYLFPPQNRLRVSCQKVIAHKMFDHVVLVFIFLNCI
TIALERPDIDPGSTERAFLSVSNYIFTAIFVVEMMVKVVALGLLWGEHAYLQSSWNVLDG
LLVLVSLVDIIVAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRP
IGNIVLICCAFFIIFGILGVQLFKGKFYYCEGTDTRNITTKAECHAAHYRWVRRKYNFDN
LGQALMSLFVLSSKDGWVNIMYDGLDAVGIDQQPVQNHNPWMLLYFISFLLIVSFFVLNM
FVGVVVENFHKCRQHQEAEEARRREEKRLRRLERRRRKAQRRPYYADYSHTRRSIHSLCT
SHYLDLFITFIICLNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRR
FFKDRWNQLDLAIVLLSIMGIALEEIEMNAALPINPTIIRIMRVLRIARVLKLLKMATGM
RALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFTNFG
MAFLTLFRVSTGDNWNGIMKDTLRECTREDKHCLSYLPALSPVYFVTFMLVAQFVLVNVV
VAVLMKHLEESNKEAREDAEMDAEIELEMAQGSTAQPPPTAQESQGTQPDTPNLLVVRKV
SVSRMLSLPNDSYMFRPVAPAAAPHSHPLQEVEMETYTGPVTSAHSPPLEPRASFQVPSA
ASSPARVSDPLCALSPRGTPRSLSLSRILCRQEAMHSESLEGKVDDVGGDSIPDYTEPAE
NMSTSQASTGAPRSPPCSPRPASVRTRKHTFGQRCISSRPPTLGGDEAEAADPADEEVSH
ITSSAHPWPATEPHSPEASPTASPVKGTMGSGRDPRRFCSVDAQSFLDKPGRPDAQRWSS
VELDNGESHLESGEVRGRASELEPALGSRRKKKMSPPCISIEPPTKDEGSSRPPAAEGGN
TTLRRRTPSCEAALHRDCPEPTEGPGTGGDPVAKGERWGQASCRAEHLTVPNFAFEPLDM
GGPGGDCFLDSDQSVTPEPRVSSLGAIVPLILETELSMPSGDCPEKEQGLYLTVPQTPLK
KPGSTPATPAPDDSGDEPV
NT seq 7080 nt   +upstreamnt  +downstreamnt
atgaccgagggcacgctggcagcggacgaagtccgggtgcccctgggcgcttcgccgccg
gcccctgcagcgccggtgagagcttccccagcgagccctggggcgccggggcgcgaggag
cagggaggatccgggtcgggcgtgttggctcccgagagcccagggaccgagtgtggtgcg
gacctgggcgccgacgaggaacagccggtcccatacccagctctggctgccacagtcttc
ttctgcctcgggcaaaccacgcggccgcgcagctggtgcctccgactggtttgtaacccg
tggttcgagcacatcagcatgctggtcatcatgctgaactgcgtgacactgggcatgttc
aggccctgtgaggatgttgagtgccgctccgaacgttgcagcatcttggaggccttcgac
gacttcatctttgccttcttcgccgtggagatggtgatcaagatggtggctttggggctg
tttgggcaaaaatgctacctgggtgacacctggaacaggctggacttcttcattgtcatg
gcgggcatgatggagtactctctggacggacacaacgtgagcctctctgccatccgaacc
gtgcgtgtgctgcggcccctccgcgccatcaaccgagtccccagtatgcggatcctggtc
actctgctgctggacacgctgcccatgcttgggaatgtcctcctcctctgcttcttcgtc
ttcttcatcttcggcattgttggggtccagctctgggctggcctgcttcggaaccgatgc
ttcctggacagcgccttcgtcaggaacaacaacctgaccttcttgcggccatactaccag
acggaggagggtgaggagaaccctttcatctgctcctcccgccgtgacaacggcatgcag
aagtgctcgcacatccccagccgccgtgagcttcgagtgcagtgcacactcggctgggag
gcctatgggcagccacaggctgaggatgggggtgctggccgcaacgcctgtatcaactgg
aaccagtattacaacgtgtgccgctcgggggaattcaaccctcacaacggtgccatcaac
ttcgacaacattggctacgcttggattgccatcttccaggtcatcacactggagggctgg
gtggacatcatgtactacgtcatggatgcccactcgttctacaacttcatctacttcatc
ctcctcatcattatgggctccttcttcatgatcaacctgtgcctggtggtgatagccaca
cagttctcagagacaaagcaaagggaaaaccagctgatgcgagaacagcgggcccgctat
ctgtccaacgacagcactctggccagcttctcagagcccggcagctgctacgaggagctc
ctcaagtatgtaggccacatcttccggaaggttaaacgccgtagcctgcgtctttatgcc
cgctggcagagccgctggcgtaagaaggtggatcccagcagtaccgtgcatggccaaggc
cctgggcggcggccacgacgggcaggcaggcgtacagcttcagtgcaccatctggtctac
caccaccaccaccaccatcaccaccattaccactttagccacggtggcccacgcaggccc
agcccagagccaggtgctggtgacaacaggttggtcagggcctgtgcgccaccctcgccg
ccatccccaggccatgggccaccagactctgagtctgtgcacagtatctaccatgctgac
tgccacgtggaggggccgcaggaacgagcccgagtggcacactccatagccactgctgct
agcctcaagctggcctcaggtttgggtaccatgaactaccccaccatcctaccttcagga
acagtcaacagcaaaggtggcaccagctcacgacccaaggggctacgaggtgctggcgcc
ccaggggctgcagtacacagccctctgagcctgggaagccccagaccctatgagaagatc
caggatgtggtgggagaacaaggactaggccgagcctctagccacctgtcaggcctgagt
gtgccttgccccctgcccagcccccaggctggcacgctgacctgtgagctgaagagctgc
ccatattgtgccagcgccctggaggaccccgagtttgaattcagtggctcagagagcggg
gactcggatgcccacggagtctatgagtttacccaggatgtacggcatggggattgtcgg
gaccctgtgcagcagccccatgaagtgggcacaccaggccacagcaatgagcggcggcgg
acaccactgcggaaggcctcacaaccaggagggataggccacctctgggcatccttcagt
ggcaagctacgtcgcattgtagacagcaagtacttcaaccgaggcatcatggcagccatc
ctcgtcaatactctgagcatgggcgttgagtatcatgaacagcctgaggagctgaccaac
gccctggagataagcaacatcgtgttcaccagcatgtttgccttggagatgctactgaag
ctgctggcctgcggcccactgggatacatccggaacccctacaacatcttcgatggcatt
gttgtcgtcataagtgtctgggagatcgtggggcaggcaaacggtggcctgtctgtgctg
cgcaccttcaggctgctgcgggtgctgaagctggtgcgcttcctgccggccctgcggcgc
cagctcgtggtgctcatgaggaccatggacaacgtggccaccttctgcatgctcctcatg
ctgttcatcttcatcttcagcatcctgggcatgcacctgttcggctgtaagttcagcctg
aagacagactctggagacaccgtccctgacaggaagaacttcgactccctactgtgggcc
atcgtcaccgtgtttcagatcttgacacaggaagactggaacgtggttctgtacaacggc
atggcctccacttcgtcctgggccgccctttactttgtggccctcatgacctttgggaac
tatgtgctcttcaacctgctggtagccatcctggtggaaggtttccaggcagagggtgac
gccaccagatctgacaccgacgaggataagacgtctacccagctagagggagatttcgat
aagctcagagatcttcgagccacagagatgaagatgtattcactggcagtgacccctaac
gggcacctagagggccgaggcagcctgccgccgcccctcatcactcacacggcagctacg
cctatgcctactcccaaaagctccccaaacctggacgtggcccatgctctcctggactct
cggcgcagcagcagcggctctgtggacccccagctgggggaccagaagtctctggccagc
ctccgcagctccccttgcaccccatggggccccaacagcgctgggagcagcaggcgctcc
agttggaacagcctgggccgcgcacccagcctcaaacgccgcaaccagtgtggggagcgc
gagtccctgctctctggagaggggaagggcagcaccgatgacgaggccgaggacagcaga
ccaagcacgggaacccacccaggggcctcgccagggccccgagccacgccactgcggcgt
gccgagtcattggaccaccgcagcacgctggacctgtgtccaccacggcctgcggccctc
ctgccgaccaagttccatgactgcaacgggcagatggtggccctgcccagcgagttcttt
ctgcgcatcgacagccacaaggaggatgcagcggagtttgatgatgacatagaggatagc
tgctgcttccgtctacacaaagtgctggaaccctatgcaccccagtggtgccgtagccgg
gagtcctgggccctgtatctcttcccaccgcagaacaggctacgcgtctcctgccagaaa
gtcatcgcacacaagatgtttgaccacgtggtccttgtcttcatcttcctcaactgtatc
accattgctctggagaggccagacattgacccaggcagcactgagcgggccttcctcagc
gtctccaactacatcttcacagccatcttcgtggtggagatgatggtgaaggtggtagcc
ctgggactgctgtggggtgaacatgcctacctacagagcagttggaatgtgctggacggg
ctgcttgtcctggtatccctggttgacatcatcgtggccatggcctcagctggcggtgcc
aagatcctaggcgtcctgcgtgtgctgcgcctgctgcggaccctgaggcctctgagggtc
atcagccgagctccaggcctcaagctggttgtagagactctgatatcatcgctcaggccc
attgggaacatcgtcctcatctgctgcgccttcttcatcatctttggcatcctcggggtg
cagcttttcaagggcaaattctactactgcgagggcacagataccaggaatatcaccacc
aaggccgagtgccatgctgcccactaccgctgggtgaggcgcaaatacaactttgacaac
ctgggtcaggcgctgatgtctctgttcgtgctgtcatctaaggatggctgggtaaacatc
atgtatgacgggctggatgccgtgggcatcgaccagcagcccgtgcagaaccacaacccc
tggatgctgctctacttcatctccttcctgctcatcgtcagcttcttcgtgctcaacatg
tttgtgggcgtggtggtggagaacttccacaagtgccggcagcaccaggaggctgaggag
gctcggcgccgggaggagaaacggctgcggcgcctggagaggaggcgcaggaaggcccag
cgccggccctactacgcagactattcacacactcgccgctccatccattcgctgtgcacc
agccactacctggacctcttcatcaccttcatcatctgcctcaatgtcatcaccatgtcc
atggagcactacaaccagcccaagtccctggatgaggccctcaagtactgcaactacgtc
tttaccatcgtcttcgtctttgaggctgcactgaagctggtggcctttgggttccggagg
ttcttcaaggacaggtggaaccagctggacttggccatcgtcctcctatccatcatgggc
attgcgctggaggagattgagatgaacgccgccctgcccatcaatcccaccatcatccgc
atcatgcgtgtgcttcgaatcgcccgtgtgctgaagctactgaagatggccacaggcatg
cgcgccttgctggatactgtggttcaagctctgcctcaggtagggaaccttggtcttctt
ttcatgctcctgttttttatctatgctgccctgggagtggagctgtttgggaggctagag
tgcagcgaggataacccctgcgagggcctgagcaggcacgctaccttcaccaacttcggc
atggccttcctcacactgttccgagtgtccactggggacaactggaatgggattatgaag
gataccctccgtgagtgtacccgtgaggacaagcactgcctcagctacctgcccgcgctc
tcacccgtctacttcgtcaccttcatgctggtggctcagttcgtgctggtcaatgtggtg
gtggccgtgctcatgaagcacctggaggagagcaacaaggaggcccgcgaggatgcagag
atggacgccgagatcgagctggagatggcacaggggtccacagcccagcccccacctaca
gcacaggaaagccaaggtacccagccagacaccccgaacctcctggtcgtgcgaaaagta
tctgtgtccaggatgctctcgctgcccaatgacagctacatgttcaggccggtggctccc
gcggctgccccacattcccacccactgcaggaagtggagatggagacctacacaggcccg
gtcacctctgctcactcgccacccctggagccccgcgcctctttccaggtcccatcagcc
gcgtcctccccagccagggtcagtgaccccctttgtgccctttcaccccggggtacaccc
cgctctctgagtctctcacggatactctgcagacaggaggccatgcactctgagtccctg
gaagggaaggttgatgatgttggaggagacagcatcccagactacacagagcctgctgaa
aatatgtccacgagccaggcatcaacaggtgccccgaggtcccctccgtgctccccgcga
cctgccagcgtccgtacccgcaagcacacgtttgggcaacgctgcatctccagccgccct
cccaccctgggaggagatgaggctgaagcagcagacccagcagatgaggaggtcagccac
atcaccagctcagcccacccctggccggctacagagccccacagccctgaggcctcccca
acagcctctcctgtgaaaggcacaatgggcagtgggcgggacccacgcaggttctgcagt
gtagatgctcagagcttcctggacaaaccaggtcggccagatgcacaacggtggtcctca
gtggaactggataacggagaaagccacctagagtccggggaagtgaggggccgggcctca
gagctcgaaccagctcttgggtcacgaaggaagaagaagatgagccctccctgcatctcc
attgaacctcccactaaggatgagggctcttcccggccccctgcagccgaaggaggcaac
actaccctgaggcgccgaaccccatcctgtgaggctgccctccatagggactgcccagag
cctacagaaggcccaggcaccggaggggaccctgtagccaagggtgagcgctggggccag
gcctcttgccgagcagagcatctgactgtccccaactttgcctttgagcctctggacatg
ggcggacctggtggagactgtttcttggacagtgaccaaagtgtgaccccagaacccaga
gtttcctctttgggggctatagtgcctctgatactagaaactgaactttctatgccctct
ggtgactgcccagagaaggaacaaggactgtacctcactgtgccccagacccccttgaag
aaaccagggtctaccccagccactcctgccccagatgacagtggagatgagcctgtgtag

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