KEGG   Rattus norvegicus (rat): 140635
Entry
140635            CDS       T01003                                 

Gene name
Flt3
Definition
(RefSeq) receptor-type tyrosine-protein kinase FLT3 precursor
  KO
K05092  fms-related tyrosine kinase 3 [EC:2.7.10.1]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04010  MAPK signaling pathway
rno04014  Ras signaling pathway
rno04151  PI3K-Akt signaling pathway
rno04640  Hematopoietic cell lineage
rno05200  Pathways in cancer
rno05202  Transcriptional misregulation in cancer
rno05221  Acute myeloid leukemia
rno05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    140635 (Flt3)
   04014 Ras signaling pathway
    140635 (Flt3)
   04151 PI3K-Akt signaling pathway
    140635 (Flt3)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    140635 (Flt3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    140635 (Flt3)
   05202 Transcriptional misregulation in cancer
    140635 (Flt3)
   05230 Central carbon metabolism in cancer
    140635 (Flt3)
  09162 Cancer: specific types
   05221 Acute myeloid leukemia
    140635 (Flt3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rno01001]
    140635 (Flt3)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:rno04090]
    140635 (Flt3)
Enzymes [BR:rno01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     140635 (Flt3)
Protein kinases [BR:rno01001]
 Receptor tyrosine kinases (RTK)
  PDGFR family [OT]
   140635 (Flt3)
CD molecules [BR:rno04090]
 Proteins
  140635 (Flt3)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase ig Ig_3 I-set Ig_2 APH Haspin_kinase TCAD9
Other DBs
NCBI-GeneID: 140635
NCBI-ProteinID: NP_001094292
RGD: 61308
Ensembl: ENSRNOG00000054764
Position
12
AA seq 1000 aa
MRALARRSDRLPLLVVLSVMILETVTNQDLPVIKCVLIIHKNNGSAAGKSSSHVMVPESP
EDLRCAPKHRSEGVVYEAVTVEVAQSASFTLQVQLTTPGDVSCLWVFKHSSLGCQPHFDL
QNRRIVSMTILNVTETQAGEYLLHIQSEATNHTVLFTVNVRDTQLYVLRRPSFRKMENQD
ALLCVSEGVPEPTVEWVVCSSHRDSCREEGSAVVKKEEKVLHELFETDIRCCARNALGRE
CTKLFTIDLNQAPQSTLPQLFLKVGEPLWIRCKAIHVNHGFGLTWELGNKVLEEGSYFEM
SSYSTNRSMIRILLAFVSSVGRNNTGYYTCSSSKHPSQTALVTILEKGFINATSSQEEYE
IDPYEKFCFSVRFKAYPQIRCKWTFSQTSFPCEQSGLEDGYSISKFCDHKNNPGEYIFHG
ENDDAQFTKMFILNIRRKPQVLANASASQASCFSDGYPLPNWTWKKCSDKSPNCTEEIPE
GVWNKKANRKVFGQWVSSSTLNMSEAGRGFLVKCCAYNSMGTSCETILLNSPGPFLFIQD
NISFYATIGLCPPFIVVLTVLICHKYKKQFRYESQLQMIQVTGPLDNEYFYIDFRDYEYD
LKWEFPRENLEFGKVLGSGAFGRVMNATAYGISKTGVSIQVAVKMLKEKADRCEREALMA
ELKMMTHLGHHDNIVNLLGACTLSGPVYLIFEYCCHGDLLNYLRSKREKFHRTWTEIFKE
HNFSFYPTFQSHSNSSMPGSREVQIYPPVDQVSGFNGNSIHSEGNIEYENQKRLEEEEEE
DLNVLTFEDLLCFAYQVAKGMEFLEFKSCVHRDLAARNVLVTHGKVVKICDFGLARDILS
DSSYVVRGNARLPVKWMAPESLFEGIYTIKSDVWSYGILLWEIFSLGVNPYPGIPVDANF
YKLIQSGFKMEQPFYATEEIYFVMQSCWAFDSRKRPSFPNLTSFLGCQLAEAEAAMYQNM
GGDVPLEHPAIYQNRRPASREAGSEPPSPQVQEKTHRERS
NT seq 3003 nt   +upstreamnt  +downstreamnt
atgcgggcgttggcgcggcgcagcgaccggctgccgctgcttgttgttttgtcagtaatg
attctcgagaccgttacaaaccaagatctgcctgtgatcaagtgtgttttaatcattcat
aagaacaatggctcggcggcgggaaagtcatcgtcgcacgtcatggttccagaatcccca
gaggacctccggtgtgccccgaagcatcggagtgaaggggtggtctatgaagctgtcact
gtggaggtggcccagtctgcgtccttcacattgcaagtacagctcaccaccccgggggat
gtttcttgcctctgggtctttaagcacagctcgctgggctgccagccacactttgattta
cagaacagaagaattgtttccatgaccatcttgaacgttacagagacccaggcaggagaa
tacctactccatattcagagtgaagccaccaaccacacggtgctgttcacagtgaatgta
agagatacacagctgtacgtgctaagaagaccttccttcagaaagatggagaaccaggac
gccctgctctgcgtctctgagggtgtcccagagcccaccgtggagtgggtggtctgcagt
tcccacagggacagctgtagagaagaaggctctgccgttgtcaaaaaggaggaaaaggta
cttcacgagctatttgaaacagacatcagatgctgtgcgagaaatgcactgggccgagaa
tgcaccaagctgttcaccatagatctaaaccaggctcctcagagcacactgccccagtta
tttctgaaagtgggggagcccttgtggataaggtgcaaggccatccatgtgaaccatgga
ttcgggctcacctgggagctgggaaacaaagtcctggaggagggcagctactttgagatg
agttcctactccaccaacagatccatgatccggattctcttggcttttgtgtcctctgtg
ggaaggaacaacaccggatattacacctgttcttcctcaaagcatcccagccagacagcg
ttggtgaccatcctagaaaaaggtttcataaatgctaccagctcacaagaagagtatgaa
attgacccgtatgaaaagttctgcttctcggtcaggtttaaagcgtacccacaaatccga
tgcaagtggaccttctctcaaacatcgtttccttgtgaacaaagtggcctggaggatggg
tacagcatttctaaattttgcgatcataagaacaacccaggagaatacatattccatgga
gaaaatgatgacgcccagttcaccaaaatgttcatactgaatataagaaggaaacctcaa
gtgctagcaaatgcctcagccagccaggcatcctgtttctctgatggctacccgttaccc
aactggacctggaagaagtgttcggacaagtcacccaactgcacggaggaaatcccagaa
ggagtttggaataaaaaggctaacagaaaagtgtttggacagtgggtgtcgagcagtacc
ctgaatatgagtgaggccgggagagggtttctggtcaaatgctgtgcatacaattctatg
ggcacgtcttgcgaaaccatccttttaaactcaccaggccccttccttttcatccaagac
aacatctccttctatgcaaccatcgggctttgcccgcctttcattgtcgtcctcactgtg
ctgatctgtcacaaatacaaaaagcaatttaggtacgaaagccagctgcagatgatccaa
gtgaccggccccctggataacgagtacttctacattgacttcagggactacgaatatgac
ctcaagtgggagtttccaagggaaaacttagagtttgggaaggtcctggggtccggcgct
tttgggagagtgatgaatgccacggcctacgggattagtaaaacaggagtctcaattcag
gtggcggtgaagatgctaaaagagaaagctgacagatgtgaaagagaggcgctcatggct
gagctcaaaatgatgacccacctggggcaccatgacaacatcgtgaacctgctgggggca
tgcacactgtcagggccagtgtacttgatttttgaatattgttgccatggtgacctgctc
aactacctaagaagcaaaagagaaaagtttcacaggacgtggacagagatttttaaggaa
cataatttcagtttttaccccaccttccagtcacattcaaactccagtatgccgggttca
cgagaagttcagatatacccgcccgtggatcaggtctcagggttcaatgggaattcaatt
cattctgaaggtaatattgagtatgaaaaccagaagaggctggaagaagaggaggaagaa
gatttgaacgtgctgacgtttgaagacctcctttgttttgcgtatcaagtggccaagggc
atggagttcctggagttcaagtcgtgtgttcacagagacctggcagccaggaacgtactg
gtcacccacgggaaggtggtgaagatctgtgactttggactggcccgagacatcctgagt
gactccagctacgtcgtcaggggcaacgcacggctgccagtgaagtggatggcacctgag
agcttgtttgaagggatctatacaatcaagagtgacgtctggtcctacggcatccttctc
tgggagatattttcattgggtgtgaacccttaccccggtattcctgtcgatgctaacttc
tataaactgattcagagtggatttaaaatggagcagccgttctatgctacggaagagata
tactttgtaatgcaatcctgctgggcttttgactcaaggaagcggccatccttccccaat
ctgacgtcatttttaggctgtcagctcgcagaggcagaagcagcgatgtatcagaacatg
ggcggcgatgtcccactggagcacccagccatctaccaaaacaggcggcctgccagcaga
gaggcaggctcagagccgccatcaccacaggttcaggagaagactcacagagaaagaagt
tag

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (8)   
   KEGG PATHWAY (8)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (2)   
   RefSeq(pep) (2)   
DNA sequence (6)   
   RefSeq(nuc) (2)   
   GenBank (2)   
   EMBL (2)   
Protein domain (9)   
   Pfam (9)   
All databases (37)   

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