KEGG   Rattus norvegicus (rat): 171378Help
Entry
171378            CDS       T01003                                 

Gene name
Ppp3cc
Definition
(RefSeq) protein phosphatase 3 catalytic subunit gamma
  KO
K04348  serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04010  MAPK signaling pathway
rno04020  Calcium signaling pathway
rno04022  cGMP-PKG signaling pathway
rno04114  Oocyte meiosis
rno04218  Cellular senescence
rno04310  Wnt signaling pathway
rno04360  Axon guidance
rno04370  VEGF signaling pathway
rno04380  Osteoclast differentiation
rno04625  C-type lectin receptor signaling pathway
rno04650  Natural killer cell mediated cytotoxicity
rno04658  Th1 and Th2 cell differentiation
rno04659  Th17 cell differentiation
rno04660  T cell receptor signaling pathway
rno04662  B cell receptor signaling pathway
rno04720  Long-term potentiation
rno04724  Glutamatergic synapse
rno04728  Dopaminergic synapse
rno04921  Oxytocin signaling pathway
rno04922  Glucagon signaling pathway
rno04924  Renin secretion
rno05010  Alzheimer disease
rno05014  Amyotrophic lateral sclerosis (ALS)
rno05031  Amphetamine addiction
rno05152  Tuberculosis
rno05163  Human cytomegalovirus infection
rno05166  Human T-cell leukemia virus 1 infection
rno05167  Kaposi sarcoma-associated herpesvirus infection
rno05170  Human immunodeficiency virus 1 infection
rno05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    171378 (Ppp3cc)
   04310 Wnt signaling pathway
    171378 (Ppp3cc)
   04370 VEGF signaling pathway
    171378 (Ppp3cc)
   04020 Calcium signaling pathway
    171378 (Ppp3cc)
   04022 cGMP-PKG signaling pathway
    171378 (Ppp3cc)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    171378 (Ppp3cc)
   04218 Cellular senescence
    171378 (Ppp3cc)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    171378 (Ppp3cc)
   04650 Natural killer cell mediated cytotoxicity
    171378 (Ppp3cc)
   04660 T cell receptor signaling pathway
    171378 (Ppp3cc)
   04658 Th1 and Th2 cell differentiation
    171378 (Ppp3cc)
   04659 Th17 cell differentiation
    171378 (Ppp3cc)
   04662 B cell receptor signaling pathway
    171378 (Ppp3cc)
  09152 Endocrine system
   04922 Glucagon signaling pathway
    171378 (Ppp3cc)
   04921 Oxytocin signaling pathway
    171378 (Ppp3cc)
   04924 Renin secretion
    171378 (Ppp3cc)
  09156 Nervous system
   04724 Glutamatergic synapse
    171378 (Ppp3cc)
   04728 Dopaminergic synapse
    171378 (Ppp3cc)
   04720 Long-term potentiation
    171378 (Ppp3cc)
  09158 Development and regeneration
   04360 Axon guidance
    171378 (Ppp3cc)
   04380 Osteoclast differentiation
    171378 (Ppp3cc)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    171378 (Ppp3cc)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    171378 (Ppp3cc)
   05014 Amyotrophic lateral sclerosis (ALS)
    171378 (Ppp3cc)
  09165 Substance dependence
   05031 Amphetamine addiction
    171378 (Ppp3cc)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    171378 (Ppp3cc)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    171378 (Ppp3cc)
   05170 Human immunodeficiency virus 1 infection
    171378 (Ppp3cc)
   05163 Human cytomegalovirus infection
    171378 (Ppp3cc)
   05167 Kaposi sarcoma-associated herpesvirus infection
    171378 (Ppp3cc)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:rno01009]
    171378 (Ppp3cc)
Enzymes [BR:rno01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     171378 (Ppp3cc)
Protein phosphatases and associated proteins [BR:rno01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     171378 (Ppp3cc)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Metallophos DUF5378
Motif
Other DBs
NCBI-GeneID: 171378
NCBI-ProteinID: NP_599194
RGD: 621616
Ensembl: ENSRNOG00000009745
UniProt: Q6AYJ0
Position
15p11
AA seq 506 aa AA seqDB search
MSGRRPQFSTTERVIKAVPFPPTRRLTLKEVFENGKPKMDVLKNHLVKEGRVEEDVALKI
INDGAAILKQEKTMLEVEAPITVCGDVHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGY
FSIECVLYLWSLKINHPKTLFLLRGNHECRHLTEYFTFKQECRIKYSELVYEACMHTFDC
LPLAALLNQQFLCVHGGMSPEITCLDDIRKLDRFAEPPAFGPVCDLLWSDPLEDYGSEKT
LEHYTHNTVRGCSYFFSYPAVCEFLQNNSLLSIIRAHEAQDAGYRMYRKNQATGFPSLIT
IFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEM
LVNILNICSDEEMSLVEEEGATSVRKEVIRNKIRAIGKMARVFTVLREESENVLILKGLT
PTGTLPLGVLSGGKQTIETAKLQAAEEREAIRGFTIAHRIRSFEEARGLDRINERMPPRK
EASYHHDAGKTHPHPSKRSDHGKKAL
NT seq 1521 nt NT seq  +upstreamnt  +downstreamnt
atgtccgggaggcgccctcagttctccacgaccgagcgcgtcatcaaagctgtccccttt
cctccaacccgacggctaactttgaaggaagtatttgagaatgggaaacctaaaatggat
gttttgaaaaaccatttggtaaaagaaggccgggtagaagaggacgtagccttaaagata
atcaatgatggggctgccatcctgaagcaagagaagactatgctagaagtggaagctcca
atcacagtgtgtggtgatgttcatggacaattctttgacctgatgaagttgtttgaagtt
gggggatcacctagtaatactcgctacctcttcctgggtgactatgtggacagaggctat
ttcagtatagagtgtgtgctgtatctgtggagcttaaagattaaccatcctaaaacattg
tttctgcttcgagggaatcatgaatgcaggcatcttacagagtacttcaccttcaaacaa
gaatgtcggatcaagtattcagagctggtgtacgaagcgtgcatgcacactttcgactgt
cttcctcttgctgccctcttaaaccagcagtttctctgtgtacacggaggaatgtctcct
gaaattacttgtttagacgacattaggaaattagataggtttgctgaacctcctgcattt
gggccagtgtgcgatctgctttggtctgatcccttagaggattatggtagtgagaagacc
ctggagcactacacccacaacactgtccgaggctgctcctacttcttcagttaccctgca
gtttgtgaatttttacagaacaatagtttattatcaataatcagagcccatgaagcccag
gatgctgggtaccgaatgtacaggaagaaccaagcaactggctttccatcactcattaca
attttctctgcccccaattacctagatgtctataacaataaagctgcagtattgaaatat
gaaaacaatgtcatgaacatcaggcagttcaactgttctccacacccttactggctccca
aacttcatggatgttttcacatggtctttgccttttgttggagaaaaagtcacagagatg
ttggtcaatattctcaacatatgctcggatgaagaaatgtccttagtcgaagaggaagga
gccacttcagttcgaaaagaagtcatcaggaataaaatccgagccattgggaaaatggca
cgggtctttacagttcttcgggaagagagtgagaatgtgctgattctcaagggcctcact
cccacaggcacactcccactcggggtcctctctggaggaaagcagaccattgagactgcc
aaactacaagcagcagaggagcgggaagccatcagaggttttacaattgcacacaggatc
cgaagttttgaagaagcccgaggtctagaccgaattaatgagagaatgccaccccgaaaa
gaggcttcttatcaccatgatgcaggaaagacacacccacacccgtcaaaaaggagcgac
catggaaagaaagccctgtaa

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