KEGG T01003: 24218

Rattus norvegicus (rat): 24218

Entry

24218             CDS       T01003

Symbol

Atp7b

Name

(RefSeq) copper-transporting ATPase 2

K17686

P-type Cu+ transporter [EC:7.2.2.8]

Organism

rno Rattus norvegicus (rat)

Pathway

rno01524

Platinum drug resistance

rno04978

Mineral absorption

Brite

KEGG Orthology (KO) [BR:rno00001]
09150 Organismal Systems
  09154 Digestive system
   04978 Mineral absorption
    24218 (Atp7b)
09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    24218 (Atp7b)
Enzymes [BR:rno01000]
7. Translocases
  7.2  Catalysing the translocation of inorganic cations
   7.2.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.2.2.8  P-type Cu+ transporter
     24218 (Atp7b)

SSDB

Motif

Pfam:

HMA E1-E2_ATPase Hydrolase HMA_PCA1 Hydrolase_3 RRM_3 Hydrolase_6 HAD_2 Zn_ribbon_DUF2089 HAD

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

RGD:

Ensembl:

UniProt:

Position

16:76654725..76726092

AA seq 1452 aa
MPEQERKVTAKEASRKILSKLALPTRPWGQSMKQSFAFDNVGYEGGLDSTCSSSTTTGVV
SILGMTCHSCVKSIEDRISSLKGIVSIKVSLEQGSATVKYVPSVLNLQQICLQIEDMGFE
ASAAEGKAASWPSRSSPAQEAVVKLRVEGMTCQSCVSSIEGKIRKLQGVVRVKVSLSNQE
AVITYQPYLIQPEDLRDHICDMGFEAAIKNRTAPLRLGPIDINKLESTNLKRAAVPPIQN
SNHLETPGHQQNHLATLPLRIDGMHCKSCVLNIEGNIGQLPGVQNIHVSLENKTAQVQYD
SSCITPLFLQTAIEALPPGYFKVSLPDGLEKESGSSSVPSLGSSQRQQEPGPCRTAVLTI
TGIPRDSSVQPMEDMLSQMKGVQQIDISLAEGTGAVLYDPSVVSSDELRTAVEDMGFEVS
VNPENITTNRVSSGNSVPQAVGDSPGSVQNMASDTRGLLTHQGPGYLSDSPPSPGGTASQ
KCFVQIKGMTCASCVSNIERSLQRHAGILSVLVALMSGKAEVKYDPEVIQSPRIAQLIED
LGFEAAIMEDNTVSEGDIELIITGMTCASCVHNIESKLTRTNGITYASVALATSKAHVKF
DPEIIGPRDIIKVIEEIGFHASLAHRNPNAHHLDHKTEIKQWKKSFLCSLVFGIPVMGLM
IYMLIPSSKPHETMVLDHNIIPGLSVLNLIFFILCTFVQFLGGWYFYVQAYKSLRHKSAN
MDVLIVLATTIAYAYSLVILVVAIAEKAEKSPVTFFDTPPMLFVFIALGRWLEHVAKSKT
SEALAKLMSLQATEATVVTLGEDNLILREEQVPMELVQRGDIIKVVPGGKFPVDGKVLEG
NTMADESLITGEAMPVTKKPGSIVIAGSINAHGSVLIKATHVGNDTTLAQIVKLVEEAQM
SKAPIQQLADRFSGYFVPFIIIISTLTLVVWIIIGFVDFGIVQKYFPSPSKHISQTEVII
RFAFQTSITVLCIACPCSLGLATPTAVMVGTGVAAQNGVLIKGGKPLEMAHKIKTVMFDK
TGTITHGVPRVMRFLLLVDVATLSLRKVLAVVGTAEASSEHPLGVAVTKYCKEELGTETL
GYSTDFQAVPGCGISCKVSNVESILAHRGPTAHPIGVGNPPIGEGTGPQTFSVLIGNREW
MRRNGLTISSDISDAMTDHEMKGQTAILVAIDGVLCGMIAIADAVKPEAALAIYTLKSMG
VDVALITGDNRKTARAIATQVGINKVFAEVLPSHKVAKVQELQNKGKKVAMVGDGVNDSP
ALAQADVGIAIGTGTDVAIEAADVVLIRNDLLDVVASIHLSKRTVRRIRVNLVLALIYNM
VGIPIAAGVFMPIGIVLQPWMGSAAMAASSVSVVLSSLQLKCYRKPDLERYEAQAHGRMK
PLSASQVSVHVGMDDRRRDSPRATPWDQVSYVSQVSLSSLTSDRLSRHGGMAEDGGDKWS
LLLSDRDEEQCI

NT seq 4359 nt +upstreamnt +downstreamnt
atgcctgaacaggagagaaaggtcacagccaaagaggccagtcggaaaatcttatctaaa
cttgctttgcccacacgaccgtggggacaatcaatgaagcagagcttcgccttcgataat
gttggctatgaagggggcctggacagcacctgctcatcctcaactaccaccggtgtggtt
agcatcctgggcatgacttgtcattcttgcgtcaagtccatcgaggacaggatctccagt
ctgaaaggcattgtgagcatcaaggtttctctggagcagggcagcgccactgtcaaatat
gtaccgtcagtcttgaacctgcagcagatttgccttcagattgaggacatgggctttgag
gccagcgctgcagaaggaaaggctgcctcctggccttccaggtcttccccagcccaggag
gcagtggtcaagctccgggtagagggcatgacctgtcagtcctgtgtcagctccatcgaa
ggcaagatccggaagctgcaaggggttgtgagagtcaaagtctccctaagcaaccaagag
gcagtcattacatatcagccttacctcattcaacccgaagacctcagggaccacatctgc
gacatgggattcgaagctgccatcaagaacagaacagctcccttaaggctgggaccaatt
gatatcaacaagttagaaagcactaacctaaagagagcagcagtccctcctatccagaat
tccaatcatttggagaccccggggcaccagcagaaccacctggccaccctcccactaaga
atagacgggatgcactgtaaatcatgtgttttgaatatcgaaggaaatataggccaactt
ccaggggttcaaaatattcatgtgtccttggagaacaaaaccgcccaagtacagtatgac
tcttcttgtatcacccccttgttcctacagacagccatcgaggcactaccacctgggtac
tttaaagtatcccttcccgatggcctagagaaggagagtggatcttccagtgtcccctcc
cttggctcctcccagagacagcaggagccaggcccatgcaggactgcggtactcaccatc
actggcattccccgtgactcgtctgttcagcccatggaagacatgctgtcccagatgaag
ggtgtgcagcaaatagacatctctttggcagaggggactggagcagttctttacgatccc
tcagtagttagctcggatgaactccggacggctgtagaagacatgggctttgaggtgtca
gtgaatcccgaaaacattactactaaccgtgtcagctctgggaattctgtgccacaagcc
gtgggtgattcaccagggtctgtgcaaaatatggcttctgacactagaggactcctcaca
caccaaggccctggctacttgtcagacagcccaccatcccctggaggaacagcatcacag
aagtgctttgtacagatcaaaggcatgacctgtgcgtcctgtgtgtctaacatagaaagg
agtctgcagagacatgccggtattctctccgtgttggtcgccttgatgtcgggaaaggca
gaggtcaagtatgacccagaggtcatccagtctcccaggatagctcagctcatcgaggac
ctgggcttcgaagcagcaatcatggaggacaacacagtctctgaaggtgacatcgaactg
attatcacagggatgacctgcgcttcctgtgttcacaacatagaatctaagctcacaagg
acaaatggcatcacttacgcctctgtggccctcgccaccagcaaagcccatgtgaagttt
gaccctgaaatcattggtccacgtgacatcatcaaggtcatcgaggaaatcggctttcat
gcttccctggcccacagaaaccccaacgctcatcacttggaccacaagacggaaataaaa
cagtggaagaaatctttcctgtgcagcctggtgtttggcatccccgtcatgggcttgatg
atctacatgctaatccccagcagtaagccccacgagaccatggtcctggaccacaacatc
attccaggactgtccgttctaaacctcattttcttcatcttgtgtaccttcgtccaattc
ctgggtgggtggtacttctatgtccaagcctacaaatcgctgagacacaagtcagccaac
atggatgtgctcatcgtactcgccacgaccattgcctatgcctactccctggtcatcctg
gtggttgccatagctgaaaaggcggagaagagcccagtgaccttctttgacacacccccc
atgctcttcgtcttcatcgccctgggacggtggctggagcacgtggcaaagagcaaaact
tcagaagccctcgcaaaactcatgtcactccaagccacagaagccacagttgtgaccctg
ggagaggacaacttaatcctcagagaggagcaagtgcccatggagctggtgcagcgaggt
gacatcatcaaggttgtccctgggggcaagttcccagtggacgggaaagtcctggaaggc
aacaccatggcagatgagtccctcatcacaggagaggccatgcctgtcaccaagaaaccc
gggagcatagtgattgctggctctataaatgctcatggctctgtgctcattaaagctacc
catgtgggcaatgacactactttggctcagattgtcaagttggtggaagaggcccagatg
tcaaaggctcccattcagcagctggctgaccggttcagtggatatttcgtcccatttatc
atcattatttcaaccttaacattggtggtgtggatcatcatcggctttgtcgattttggt
attgttcagaagtactttcctagccctagcaagcatatctcacagacagaggtgatcatc
cgctttgccttccagacgtccatcaccgtcctgtgcatcgcctgcccctgctccctcggg
ctggccacacccacagcagttatggtgggcactggggtggctgcccagaacggcgtccta
atcaagggagggaagcctctggagatggcacacaagataaagaccgttatgtttgacaaa
acgggcaccattacccacggggtccccagagtcatgcggtttctgctgcttgtggacgtg
gctaccctatccctcaggaaggttctggctgtggtgggcaccgcagaggccagcagtgag
caccccttaggcgtggccgtcactaaatactgcaaagaggaactcgggacggagaccctg
gggtacagcacggacttccaggcagtgccagggtgtggaattagctgcaaagttagcaac
gtggaaagtatcctggctcacagaggtccaaccgctcacccgattggggttggcaaccct
cccataggagaaggtacaggtccccagactttctctgtgctgattggaaaccgggaatgg
atgaggcgcaatggtttaaccatctccagtgacatcagtgacgccatgacagatcatgaa
atgaaaggacagacggccatcctggtggccattgatggtgtgctgtgcgggatgatcgcc
attgcagatgctgttaaaccagaggctgccctggctatctacaccctgaaaagcatgggc
gtggatgtggctctgatcacaggggacaaccggaagacagccagagccattgccactcag
gttggcatcaacaaagtctttgctgaggtactgccttctcacaaggtggccaaggtccag
gagcttcagaacaaagggaaaaaagtcgccatggtgggagacggggtgaacgactcccca
gccttggcccaggctgacgtgggcattgctattgggactgggacagatgtcgccatcgaa
gcagccgacgtggtccttataagaaatgacttactggacgtggtggccagcattcatctc
tccaagaggaccgtccggaggatccgggtcaatctggtgctggcgttgatttataacatg
gttgggatacccattgctgcaggtgtcttcatgcccattggcatcgtgctgcagccatgg
atgggctcagcggccatggccgcctcctctgtgtccgtggtgctctcctctcttcagctc
aagtgctacagaaagcccgacctagagagatatgaggcacaggcccatggacgcatgaag
cctctgagtgcatcccaagtcagcgtgcacgttggcatggatgaccggcggcgggattct
cccagggccacaccctgggaccaggtcagctacgtgagccaagtctctctgtcttccctg
acgtcagacagattgtctcggcatggcggtatggcagaggatggtggagacaaatggtcc
ctgctcctgagtgacagggatgaagagcagtgcatctga

All links

Gene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (4)   
   UniProt (1)   
   RefSeq(pep) (3)   
DNA sequence (17)   
   RefSeq(nuc) (3)   
   GenBank (7)   
   EMBL (7)   
Protein domain (10)   
   Pfam (10)   
All databases (36)   

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