KEGG   Rattus norvegicus (rat): 24246Help
Entry
24246             CDS       T01003                                 

Gene name
Camk2d, CAMK1, Camk2, Camki, RATCAMKI
Definition
(RefSeq) calcium/calmodulin-dependent protein kinase II delta
  KO
K04515  calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04012  ErbB signaling pathway
rno04020  Calcium signaling pathway
rno04024  cAMP signaling pathway
rno04066  HIF-1 signaling pathway
rno04114  Oocyte meiosis
rno04217  Necroptosis
rno04261  Adrenergic signaling in cardiomyocytes
rno04310  Wnt signaling pathway
rno04360  Axon guidance
rno04713  Circadian entrainment
rno04720  Long-term potentiation
rno04722  Neurotrophin signaling pathway
rno04725  Cholinergic synapse
rno04728  Dopaminergic synapse
rno04740  Olfactory transduction
rno04750  Inflammatory mediator regulation of TRP channels
rno04911  Insulin secretion
rno04912  GnRH signaling pathway
rno04916  Melanogenesis
rno04921  Oxytocin signaling pathway
rno04922  Glucagon signaling pathway
rno04925  Aldosterone synthesis and secretion
rno04934  Cushing syndrome
rno04971  Gastric acid secretion
rno05031  Amphetamine addiction
rno05152  Tuberculosis
rno05200  Pathways in cancer
rno05205  Proteoglycans in cancer
rno05214  Glioma
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    24246 (Camk2d)
   04310 Wnt signaling pathway
    24246 (Camk2d)
   04066 HIF-1 signaling pathway
    24246 (Camk2d)
   04020 Calcium signaling pathway
    24246 (Camk2d)
   04024 cAMP signaling pathway
    24246 (Camk2d)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    24246 (Camk2d)
   04217 Necroptosis
    24246 (Camk2d)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    24246 (Camk2d)
   04922 Glucagon signaling pathway
    24246 (Camk2d)
   04912 GnRH signaling pathway
    24246 (Camk2d)
   04921 Oxytocin signaling pathway
    24246 (Camk2d)
   04916 Melanogenesis
    24246 (Camk2d)
   04925 Aldosterone synthesis and secretion
    24246 (Camk2d)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    24246 (Camk2d)
  09154 Digestive system
   04971 Gastric acid secretion
    24246 (Camk2d)
  09156 Nervous system
   04725 Cholinergic synapse
    24246 (Camk2d)
   04728 Dopaminergic synapse
    24246 (Camk2d)
   04720 Long-term potentiation
    24246 (Camk2d)
   04722 Neurotrophin signaling pathway
    24246 (Camk2d)
  09157 Sensory system
   04740 Olfactory transduction
    24246 (Camk2d)
   04750 Inflammatory mediator regulation of TRP channels
    24246 (Camk2d)
  09158 Development
   04360 Axon guidance
    24246 (Camk2d)
  09159 Environmental adaptation
   04713 Circadian entrainment
    24246 (Camk2d)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    24246 (Camk2d)
   05205 Proteoglycans in cancer
    24246 (Camk2d)
  09162 Cancer: specific types
   05214 Glioma
    24246 (Camk2d)
  09165 Substance dependence
   05031 Amphetamine addiction
    24246 (Camk2d)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    24246 (Camk2d)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    24246 (Camk2d)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rno01001]
    24246 (Camk2d)
Enzymes [BR:rno01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.17  Ca2+/calmodulin-dependent protein kinase
     24246 (Camk2d)
Protein kinases [BR:rno01001]
 Serine/threonine kinases: CAMK group
  CAMK2 family
   24246 (Camk2d)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Pkinase CaMKII_AD Pkinase_Tyr DUF4440 SnoaL_3 Pkinase_fungal Kdo SnoaL_2 SnoaL_4 DUF4915
Motif
Other DBs
NCBI-GeneID: 24246
NCBI-ProteinID: NP_036651
RGD: 2263
Ensembl: ENSRNOG00000011589
UniProt: P15791
Structure
PDB: 

Position
2q42
AA seq 533 aa AA seqDB search
MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER
EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT
VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL
KGAILTTMLATRNFSAAKSLLKKPDGVKINNKANVVTSPKENIPTPALEPQTTVIHNPDG
NKESTESSNTTIEDEDVKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALG
NLVEGMDFHRFYFENALPKINKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGNGMPKT
MQSEETRVWHRRDGKWQNIHFHRSGSPTVPIKPPCIPNGKENFSGGTSLWQNI
NT seq 1602 nt NT seq  +upstreamnt  +downstreamnt
atggcttcgaccaccacctgcacccggttcaccgacgagtatcagctcttcgaggagctc
ggaaagggggcattctcagtggtgagaagatgcatgaaaatccctactggacaagagtat
gctgccaaaattatcaacaccaaaaagctttctgctagggatcatcagaaactggaaagg
gaagctagaatctgccgtctcttgaagcaccccaatattgtgagacttcatgacagcata
tccgaagagggcttccattacttggtgtttgacttagttactggtggcgaactctttgaa
gacatagtggcaagagaatattacagtgaggctgatgccagtcattgtatacaacagatt
ctagagagtgtaaatcattgtcacctaaatggcatagttcacagggacctgaagcctgag
aatttgcttttagctagcaaatccaaaggagcagctgtgaaactggcagacttcggctta
gccatagaagttcaaggcgaccagcaggcgtggtttggttttgctggcacacctgggtat
ctttctccagaagtcctacgtaaagatccttatggaaaaccagtggacatgtgggcatgt
ggcgtcatcctctacatcttgctggtgggatacccacccttctgggatgaagatcagcat
agactgtatcagcagatcaaggctggagcgtacgattttccatcaccagaatgggacaca
gtgacacctgaagccaaagacctcatcaacaaaatgctgaccatcaaccctgccaaacgc
atcacagcctctgaggccctgaaacacccatggatctgtcaacgttctactgttgcctcc
atgatgcacaggcaggagactgtagactgcttgaagaaatttaatgctcgacggaaattg
aagggtgccatcttgacaactatgctggctacgagaaatttttcagcagccaagagtttg
ttgaagaaaccggatggggtaaagataaacaacaaagccaacgtggtaaccagccccaaa
gaaaatattcctaccccggcgctggagccccaaactactgtaatccacaaccctgatgga
aacaaggagtcaactgagagctcaaataccaccattgaggatgaagacgtgaaagcacga
aagcaagagatcatcaaagtcactgagcagctgattgaagctatcaacaatggggacttc
gaggcttacacgaaaatctgtgatccaggcctcactgcctttgaacccgaagcattgggc
aacttagtggaagggatggactttcacagattctactttgaaaatgctttgcccaaaatc
aataaaccaatccacactatcatcctgaaccctcacgtacacctggtaggggatgatgca
gcctgcatagcatacattcggctcacacagtacatggatggaaatggaatgccaaagaca
atgcagtcagaagagactcgagtgtggcaccgccgtgatgggaagtggcagaatattcac
tttcatcgttcggggtccccaacagtccccatcaagccaccctgtattccaaatgggaaa
gaaaacttctcaggaggcacctctttgtggcaaaacatctga

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