KEGG   Rattus norvegicus (rat): 24410
Entry
24410             CDS       T01003                                 
Symbol
Grin2b
Name
(RefSeq) glutamate receptor ionotropic, NMDA 2B precursor
  KO
K05210  glutamate receptor ionotropic, NMDA 2B
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04014  Ras signaling pathway
rno04015  Rap1 signaling pathway
rno04020  Calcium signaling pathway
rno04024  cAMP signaling pathway
rno04080  Neuroactive ligand-receptor interaction
rno04082  Neuroactive ligand signaling
rno04713  Circadian entrainment
rno04720  Long-term potentiation
rno04724  Glutamatergic synapse
rno04728  Dopaminergic synapse
rno05010  Alzheimer disease
rno05014  Amyotrophic lateral sclerosis
rno05016  Huntington disease
rno05017  Spinocerebellar ataxia
rno05020  Prion disease
rno05022  Pathways of neurodegeneration - multiple diseases
rno05030  Cocaine addiction
rno05031  Amphetamine addiction
rno05033  Nicotine addiction
rno05034  Alcoholism
rno05322  Systemic lupus erythematosus
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    24410 (Grin2b)
   04015 Rap1 signaling pathway
    24410 (Grin2b)
   04020 Calcium signaling pathway
    24410 (Grin2b)
   04024 cAMP signaling pathway
    24410 (Grin2b)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    24410 (Grin2b)
   04082 Neuroactive ligand signaling
    24410 (Grin2b)
 09150 Organismal Systems
  09156 Nervous system
   04724 Glutamatergic synapse
    24410 (Grin2b)
   04728 Dopaminergic synapse
    24410 (Grin2b)
   04720 Long-term potentiation
    24410 (Grin2b)
  09159 Environmental adaptation
   04713 Circadian entrainment
    24410 (Grin2b)
 09160 Human Diseases
  09163 Immune disease
   05322 Systemic lupus erythematosus
    24410 (Grin2b)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    24410 (Grin2b)
   05014 Amyotrophic lateral sclerosis
    24410 (Grin2b)
   05016 Huntington disease
    24410 (Grin2b)
   05017 Spinocerebellar ataxia
    24410 (Grin2b)
   05020 Prion disease
    24410 (Grin2b)
   05022 Pathways of neurodegeneration - multiple diseases
    24410 (Grin2b)
  09165 Substance dependence
   05030 Cocaine addiction
    24410 (Grin2b)
   05031 Amphetamine addiction
    24410 (Grin2b)
   05033 Nicotine addiction
    24410 (Grin2b)
   05034 Alcoholism
    24410 (Grin2b)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:rno04040]
    24410 (Grin2b)
Ion channels [BR:rno04040]
 Ligand-gated channels
  Glutamate (ionotropic)
   24410 (Grin2b)
SSDB
Motif
Pfam: NMDAR2_C Lig_chan Lig_chan-Glu_bd ANF_receptor SBP_bac_3
Other DBs
NCBI-GeneID: 24410
NCBI-ProteinID: NP_036706
RGD: 2738
Ensembl: ENSRNOG00000008766
UniProt: Q00960
Structure
Position
4:complement(170297811..170775420)
AA seq 1482 aa
MKPSAECCSPKFWLVLAVLAVSGSKARSQKSPPSIGIAVILVGTSDEVAIKDAHEKDDFH
HLSVVPRVELVAMNETDPKSIITRICDLMSDRKIQGVVFADDTDQEAIAQILDFISAQTL
TPILGIHGGSSMIMADKDESSMFFQFGPSIEQQASVMLNIMEEYDWYIFSIVTTYFPGYQ
DFVNKIRSTIENSFVGWELEEVLLLDMSLDDGDSKIQNQLKKLQSPIILLYCTKEEATYI
FEVANSVGLTGYGYTWIVPSLVAGDTDTVPSEFPTGLISVSYDEWDYGLPARVRDGIAII
TTAASDMLSEHSFIPEPKSSCYNTHEKRIYQSNMLNRYLINVTFEGRNLSFSEDGYQMHP
KLVIILLNKERKWERVGKWKDKSLQMKYYVWPRMCPETEEQEDDHLSIVTLEEAPFVIVE
SVDPLSGTCMRNTVPCQKRIISENKTDEEPGYIKKCCKGFCIDILKKISKSVKFTYDLYL
VTNGKHGKKINGTWNGMIGEVVMKRAYMAVGSLTINEERSEVVDFSVPFIETGISVMVSR
SNGTVSPSAFLEPFSADVWVMMFVMLLIVSAVAVFVFEYFSPVGYNRCLADGREPGGPSF
TIGKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQEEYV
DQVSGLSDKKFQRPNDFSPPFRFGTVPNGSTERNIRNNYAEMHAYMGKFNQRGVDDALLS
LKTGKLDAFIYDAAVLNYMAGRDEGCKLVTIGSGKVFASTGYGIAIQKDSGWKRQVDLAI
LQLFGDGEMEELEALWLTGICHNEKNEVMSSQLDIDNMAGVFYMLGAAMALSLITFICEH
LFYWQFRHCFMGVCSGKPGMVFSISRGIYSCIHGVAIEERQSVMNSPTATMNNTHSNILR
LLRTAKNMANLSGVNGSPQSALDFIRRESSVYDISEHRRSFTHSDCKSYNNPPCEENLFS
DYISEVERTFGNLQLKDSNVYQDHYHHHHRPHSIGSTSSIDGLYDCDNPPFTTQPRSISK
KPLDIGLPSSKHSQLSDLYGKFSFKSDRYSGHDDLIRSDVSDISTHTVTYGNIEGNAAKR
RKQQYKDSLKKRPASAKSRREFDEIELAYRRRPPRSPDHKRYFRDKEGLRDFYLDQFRTK
ENSPHWEHVDLTDIYKERSDDFKRDSVSGGGPCTNRSHLKHGTGEKHGVVGGVPAPWEKN
LTNVDWEDRSGGNFCRSCPSKLHNYSSTVAGQNSGRQACIRCEACKKAGNLYDISKDNSL
QELDQPAAPVAVTSNASSTKYPQSPTNSKAQKKNRNKLRRQHSYDTFVDLQKEEAALAPR
SVSLKDKGRFMDGSPYAHMFEMPAGESSFANKSSVPTAGHHHNNPGSGYMLSKSLYPDRV
TQNPFIPTFGDDQCLLHGSKSYFFRQPTVAGASKTRPDFRALVTNKPVVSALHGAVPGRF
QKDICIGNQSNPCVPNNKNPRAFNGSSNGHVYEKLSSIESDV
NT seq 4449 nt   +upstreamnt  +downstreamnt
atgaagcccagcgcagagtgctgttcccccaagttctggttggtgttggccgtcttggcc
gtatcaggcagcaaagctcgttcccaaaagagcccccccagcatcggcatcgctgtcatc
ctcgtgggcacttcagacgaagtggccataaaagacgcccacgagaaagatgacttccat
catctctcagtagttccccgggtggagctggtagccatgaacgaaactgacccaaagagc
atcatcacccgtatctgcgatcttatgtctgaccggaagatccagggggtggtgttcgcg
gatgacaccgaccaagaagccatcgctcagatcctcgacttcatttctgctcagactctc
acccccatcctgggcatccatgggggctcatctatgataatggcggataaggatgagtcc
tccatgttcttccagtttggcccgtctatcgaacagcaagcttccgtcatgctcaacatc
atggaagaatatgactggtacatcttttccatcgtcaccacctacttccctggctaccag
gactttgtgaacaagatccgcagtaccatcgagaacagcttcgtgggctgggagctcgag
gaagtcctcctgctagacatgtctctggacgatggcgactctaagattcagaatcagctg
aagaagctccaaagccccatcattctcctttattgcacgaaggaggaagccacctacatt
tttgaagtagctaactcagttgggctgactggctacggctacacgtggattgtgccgagt
ctggtggccggggatacggacacggtgccttcagagttccccacggggcttatctctgtg
tcttatgatgaatgggactatggccttcctgccagagtgagagatggaattgccatcatc
accactgctgcctcggacatgctgtccgaacacagtttcatccctgagcccaagagcagt
tgctacaacacccacgagaagaggatctaccagtctaacatgttgaataggtatctgatc
aatgtcacttttgaagggagaaacctgtccttcagcgaagatggctaccagatgcatccg
aagctggtgataatccttctgaacaaggagaggaagtgggagagggtggggaaatggaag
gacaagtccctgcagatgaagtattatgtgtggcctcggatgtgtcctgagactgaggag
caagaggatgaccatctgagcattgtcaccttggaggaggcgccatttgtcattgtggaa
agcgtggaccctctcagtggaacctgcatgaggaatacagtcccgtgccagaagcgcatc
atctctgagaataaaacagatgaggaaccaggctacatcaaaaaatgctgcaaggggttc
tgtattgacatccttaagaaaatttctaagtctgtgaagttcacctatgacctttacctg
gtgaccaatggcaagcacgggaagaagattaatgggacctggaatggcatgatcggtgag
gtggtcatgaagagggcctacatggcagtgggatcactaactatcaatgaagaacggtca
gaggtggttgacttctctgtacccttcatagaaactggcatcagtgtcatggtatctcgc
agcaatgggactgtgtcaccttctgccttcttagagccattcagcgctgacgtgtgggtg
atgatgtttgtgatgctgctcattgtttctgcggtggctgtctttgtctttgaatacttc
agccctgtgggttacaacaggtgcctagccgatggcagagagccaggaggcccatctttc
accatcggcaaagcaatttggttactctggggtctggtgtttaacaactccgtacctgtg
cagaacccaaaggggaccacctccaagatcatggtgtcagtgtgggccttctttgctgtc
attttcctggccagctacactgccaacttagcagccttcatgatccaagaggagtatgtg
gaccaggtttctggcctgagtgacaagaagttccagagacctaatgacttctcaccccct
ttccgctttgggactgtgcccaatggcagcacagagaggaatatccgtaataactatgca
gaaatgcatgcctacatgggaaagttcaaccaaaggggtgtagatgatgcattgctctcc
ctgaaaacagggaagcttgatgcattcatctatgatgcagctgtgctcaactacatggct
ggaagggacgaaggctgcaaactggtgaccattggcagtggcaaggtctttgcttctacc
ggctatggcattgctatccaaaaggactccgggtggaagcgccaggtggacctggctatc
ctgcagctgtttggagatggggagatggaagaactggaagctctctggctcactggcatt
tgccacaatgagaagaatgaggtgatgagcagccagctggacatcgacaatatggcaggt
gtcttctatatgttgggggcagccatggccctcagcctcatcaccttcatctgtgagcat
ctgttctattggcagttccggcattgcttcatgggtgtctgttctggcaagcctggcatg
gtcttctccatcagcagaggtatctacagctgtatccatggggtagccatagaggagcgc
caatccgtgatgaactcccccactgccaccatgaacaacacccactccaacatcctacgc
ttgctccgcacggccaagaacatggccaacctgtctggagtaaacggctcccctcagagt
gccctggacttcatccgccgagagtcctccgtctacgacatctctgagcatcgtcgcagc
ttcacgcattcagactgcaagtcttacaataacccaccctgtgaggaaaacctgttcagt
gactacattagcgaggtagagagaacatttggtaacctgcagctgaaggacagcaatgtg
taccaagaccactatcaccatcaccaccggccacacagcatcggcagcaccagctccatt
gatgggctctatgactgtgacaacccacccttcaccacccagcccaggtcaatcagcaag
aaacccctggacatcggcctgccctcctccaaacatagccagctcagcgacctgtatggc
aagttctctttcaagagtgaccgctacagtggccacgacgacttgattcgatcggatgtc
tccgacatctccacgcacactgtcacctatgggaacatcgagggcaacgcagccaagagg
aggaaacagcagtataaggacagtctaaagaagcggccagcctcggccaaatcgaggagg
gagtttgatgaaatcgagctggcctaccgtcgccgaccaccccgctccccggaccacaag
cgctacttcagggacaaagaagggctccgagacttctacctggaccagttccgaacaaag
gagaactcgcctcactgggagcacgtggacttgactgacatttacaaagaacgcagtgac
gacttcaagcgagattcggtcagtggaggtgggccctgtaccaacaggtctcacctcaaa
cacggaacgggcgagaagcacggagtggtaggcggggtgcctgctccttgggagaagaac
ctgaccaatgtggattgggaggaccggtctgggggcaacttctgccgcagctgtccttcc
aagctgcacaattactcctcgacggtggcagggcagaactcgggccggcaggcctgcatc
agatgtgaggcctgtaagaaggctggtaacctgtacgacatcagcaaggacaactccctg
caggaactggaccagccggctgcccccgtggctgtgacatccaacgcctccagcaccaag
taccctcaaagcccgactaattccaaggctcagaagaagaatcggaacaaactgcgccgg
cagcattcctacgacaccttcgtggacctgcagaaggaggaggccgccttggccccacgc
agcgtgagcctgaaagacaagggccgattcatggatgggagcccctacgcccatatgttt
gagatgccagctggtgagagctcctttgccaacaagtcctcagtgcccactgccggacac
caccacaacaaccccggcagcggctacatgctcagcaagtcgctctaccctgaccgggtc
acgcaaaaccctttcatccccacttttggggatgaccagtgcttgcttcacggcagcaaa
tcctacttcttcaggcagcccacggtggcaggggcgtcaaaaacaaggccggacttccgg
gcccttgtcaccaataagccagtggtgtcagcccttcatggggctgtgccaggtcgtttc
cagaaggacatttgtatagggaaccagtccaacccctgtgtgcctaacaacaaaaacccc
agggctttcaatggctccagcaatggacatgtttatgagaaactttctagtattgagtct
gatgtctga

  All links  
Gene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (8)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (6)   
DNA sequence (10)   
   RefSeq(nuc) (6)   
   GenBank (2)   
   EMBL (2)   
3D Structure (53)   
   PDB (53)   
Protein domain (5)   
   Pfam (5)   
All databases (81)   

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