KEGG   Rattus norvegicus (rat): 24411Help
Entry
24411             CDS       T01003                                 

Gene name
Grin2c, GluN2C, NR2C
Definition
(RefSeq) glutamate ionotropic receptor NMDA type subunit 2C
  KO
K05211  glutamate receptor ionotropic, NMDA 2C
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04020  Calcium signaling pathway
rno04024  cAMP signaling pathway
rno04080  Neuroactive ligand-receptor interaction
rno04713  Circadian entrainment
rno04720  Long-term potentiation
rno04724  Glutamatergic synapse
rno05010  Alzheimer disease
rno05014  Amyotrophic lateral sclerosis (ALS)
rno05030  Cocaine addiction
rno05031  Amphetamine addiction
rno05033  Nicotine addiction
rno05034  Alcoholism
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    24411 (Grin2c)
   04024 cAMP signaling pathway
    24411 (Grin2c)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    24411 (Grin2c)
 09150 Organismal Systems
  09156 Nervous system
   04724 Glutamatergic synapse
    24411 (Grin2c)
   04720 Long-term potentiation
    24411 (Grin2c)
  09159 Environmental adaptation
   04713 Circadian entrainment
    24411 (Grin2c)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    24411 (Grin2c)
   05014 Amyotrophic lateral sclerosis (ALS)
    24411 (Grin2c)
  09165 Substance dependence
   05030 Cocaine addiction
    24411 (Grin2c)
   05031 Amphetamine addiction
    24411 (Grin2c)
   05033 Nicotine addiction
    24411 (Grin2c)
   05034 Alcoholism
    24411 (Grin2c)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:rno04040]
    24411 (Grin2c)
Ion channels [BR:rno04040]
 Ligand-gated channels
  Glutamate (ionotropic)
   24411 (Grin2c)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Lig_chan Lig_chan-Glu_bd SBP_bac_3 ANF_receptor NMDAR2_C
Motif
Other DBs
NCBI-GeneID: 24411
NCBI-ProteinID: NP_036707
RGD: 2739
Ensembl: ENSRNOG00000003280
UniProt: Q00961 A0A0G2JSH8
Position
10q32.1
AA seq 1250 aa AA seqDB search
MPALVSLQDPPVDMGGALGPALLLTSLLGAWARLGAGQGEQAVTVAVVFGSSGPLQTQAR
TRLTSQNFLDLPLEIQPLTVGVNNTNPSSILTQICGLLGAARVHGIVFEDNVDTEAVAQL
LDFVSSQTHVPILSISGGSAVVLTPKEPGSAFLQLGVSLEQQLQVLFKVLEEYDWSAFAV
ITSLHPGHALFLEGVRAVADASYLSWRLLDVLTLELGPGGPRARTQRLLRQVDAPVLVAY
CSREEAEVLFAEAAQAGLVGPGHVWLVPNLALGSTDAPPAAFPVGLISVVTESWRLSLRQ
KVRDGVAILALGAHSYRRQYGTLPAPAGDCRSHPGPVSPAREAFYRHLLNVTWEGRDFSF
SPGGYLVRPTMVVIALNRHRLWEMVGRWDHGVLYMKYPVWPRYSTSLQPVVDSRHLTVAT
LEERPFVIVESPDPGTGGCVPNTVPCRRQSNHTFSSGDLTPYTKLCCKGFCIDILKKLAK
VVKFSYDLYLVTNGKHGKRVRGVWNGMIGEVYYKRADMAIGSLTINEERSEIIDFSVPFV
ETGISVMVSRSNGTVSPSAFLEPYSPAVWVMMFVMCLTVVAITVFMFEYFSPVSYNQNLT
KGKKPGGPSFTIGKSVWLLWALVFNNSVPIENPRGTTSKIMVLVWAFFAVIFLASYTANL
AAFMIQEQYIDTVSGLSDKKFQRPQDQYPPFRFGTVPNGSTERNIRSNYRDMHTHMVKFN
QRSVEDALTSLKMGKLDAFIYDAAVLNYMAGKDEGCKLVTIGSGKVFATTGYGIAMQKDS
HWKRAIDLALLQLLGDGETQKLETVWLSGICQNEKNEVMSSKLDIDNMAGVFYMLLVAMG
LALLVFAWEHLVYWKLRHSVPNSSQLDFLLAFSRGIYSCFNGVQSLPSPARPPSPDLTAD
SAQANVLKMLQAARDMVNTADVSSSLDRATRTIENWGNNRRVPAPTASGPRSSTPGPPGQ
PSPSGWGPPGGGRTPLARRAPQPPARPATCGPPLPDVSRPSCRHASDARWPVRVGHQGPH
VSASERRALPERSLLPAHCHYSSFPRAERSGRPYLPLFPEPPEPDDLPLLGPEQLARREA
MLRAAWARGPRPRHASLPSSVAEAFTRSNPLPARCTGHACACPCPQSRPSCRHLAQAQSL
RLPSYPEACVEGVPAGVATWQPRQHVCLHAHTRLPFCWGTVCRHPPPCTSHSPWLIGTWE
PPAHRVRTLGLGTGYRDSGVLEEVSREACGTQGFPRSCTWRRVSSLESEV
NT seq 3753 nt NT seq  +upstreamnt  +downstreamnt
atgcctgctctggtttctctgcaggaccctccagtggacatgggtggggccctagggccc
gccctgctgctcacttcactccttggtgcttgggcaaggctgggcgcagggcagggagaa
caggccgtgactgtggcggtggtgtttggcagctctgggccactgcagacccaggcccgg
actcgtcttacctcccagaacttcctggacctgcctctggagatccagccactcaccgta
ggggtcaacaataccaatcccagcagcatcctcacccaaatctgcgggcttctgggtgcc
gcccgtgtccacggcatcgtctttgaggacaacgtggacaccgaggccgtggcccagcta
ctggacttcgtctcctcccagacccacgtgcccatcctcagcatcagcggaggctctgct
gtggtcctcacccccaaggagccaggctccgccttcctacagctgggcgtgtccctggag
cagcagctgcaggtgctgttcaaggtgctggaggaatacgactggagcgcgttcgcggtc
atcaccagcctgcatccgggccacgcgctcttcctcgaaggcgtgcgcgccgtcgcggac
gccagctacctgagctggcggctgctggacgtgctcacgctggagctaggtccgggtggg
ccgcgagcgcgcactcagcgcctgctacgccaggtcgacgcgccggtgctggtggcttac
tgctcccgtgaagaggccgaggtgctcttcgctgaggctgcacaggctggcctggtggga
cccgggcacgtgtggttggtacctaacctggcgctgggaagcaccgacgcaccccctgca
gctttcccggtgggcctcatcagtgtggtcaccgagagttggcgccttagtctacgccag
aaggttcgcgacggagtggccattctggccctcggtgcccacagctaccgacgccagtac
ggtaccctgccagccccggctggggactgccgaagccacccgggacccgtcagccctgct
agggaggccttctacaggcatctgctgaatgtcacctgggagggccgagacttctctttc
agccctggtgggtacctggttcggcccaccatggttgtgatcgccctcaaccggcaccgc
ctctgggagatggtgggacggtgggaccatggagtcctgtacatgaagtatccagtatgg
cctcgctacagcacttctctgcagcctgtggtggacagccggcacctgacagtggccaca
ctggaagaaaggccctttgtcattgtggagagccctgaccctggcacaggtggctgtgtt
cccaacaccgtgccctgccgcagacagagcaaccacaccttcagcagcggggatctaacc
ccctacaccaagctctgttgtaagggcttctgcatcgacatcctcaaaaagctggccaag
gtggtcaagttctcctacgacttgtacctggtgaccaacggcaaacacggcaagagggtt
cgtggtgtgtggaacggcatgatcggggaggtatactacaagcgggcagacatggccatc
ggctccctcaccatcaatgaggagcgctctgagattatagatttctctgtgccttttgtg
gagaccggcatcagtgttatggtatcaaggagcaacggcaccgtctccccctcagctttt
ctggaaccctacagccctgccgtgtgggtgatgatgttcgtgatgtgtctcacggtggtt
gccatcactgtcttcatgttcgagtacttcagccctgtcagctacaaccagaacctcacc
aagggcaagaaacctggtggaccatctttcaccattggcaagtccgtgtggttgctgtgg
gcactggtcttcaacaactctgttcccatcgagaacccccggggtaccaccagcaagatc
atggtcctggtgtgggccttcttcgctgtcatcttcctcgctagctatacggccaatctg
gcggccttcatgatccaggagcaatacatcgacactgtgtcgggccttagtgacaagaag
tttcagcggcctcaagaccaatacccacccttccgttttggcacggtacctaacggcagc
acagagaggaacatccgtagcaactaccgtgacatgcacacccacatggtcaagttcaac
cagcgctcggtggaggacgctctcacaagcctgaagatggggaagctggacgccttcatc
tatgatgctgctgtgctcaactacatggcgggcaaggacgaaggctgcaagctggtcacc
attgggtctggcaaagtctttgccaccactggctatggcattgccatgcagaaagactcc
cactggaagcgggccatagacctggcactcctgcaacttctgggggatggagagacgcag
aagctggagacagtgtggctctcagggatctgccagaacgagaagaatgaggtgatgagc
agcaagctggacattgacaacatggcgggggtcttctacatgctgttggtggccatggga
ctggcccttctggtctttgcctgggagcacctggtctactggaaacttcgacactcggtg
cccaactcatcccagctggacttcctgctggctttcagcaggggcatctacagctgcttc
aacggggtacagagccttccgagtcccgcacggccgcccagcccggatctcaccgcagac
tcagcccaggccaatgtgctgaagatgctgcaggcggcccgagacatggtgaacaccgcg
gacgtgagcagctctttggaccgcgccactcgcaccatcgagaactggggcaacaaccgc
cgcgtgcctgctcccaccgcctctggcccgcggtcctccaccccgggtcctccgggacaa
ccgagccccagcggctgggggcctcctggtgggggccgcaccccgctagcgcgcagggcc
ccgcagcctccggctcgccccgcgacgtgcgggccacctttgcccgatgtgtcccgacca
tcctgcaggcacgcttcggacgcgcggtggccggtgcgagttgggcatcagggaccgcac
gtctcggcttccgagcggcgcgcgctcccggagcgctctctgttgcccgcgcactgccac
tacagttccttccctcgagcggagagatccgggcgcccctacctcccgttattcccggag
cccccggagcccgacgacctgcctctgctcgggccggaacagctggctcggcgggaagca
atgctgcgcgcggcctgggcccggggcccgcgccctcgccacgcttccttgcccagctcg
gtggcagaagctttcactcgatccaaccctctgcctgccaggtgtaccggtcacgcctgt
gcctgcccgtgcccccaaagccggccatcctgcaggcacttggctcaggcacagtcgctg
aggctgccgtcctacccggaggcctgtgtggagggcgtaccagcaggggtggccacctgg
cagcccagacagcacgtctgcctgcacgcccatacccgcctgccgttctgttggggaact
gtctgccgtcaccctccaccctgtaccagccacagcccctggctcattggaacctgggag
cctccagcacacagagtcaggaccctggggctaggcacaggctacagggacagtggggtg
ctggaagaggtcagcagggaagcctgtgggacacaaggttttccaaggtcctgcacctgg
aggcgggtctccagcctggaatcagaagtgtga

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