KEGG   Rattus norvegicus (rat): 24511
Entry
24511             CDS       T01003                                 

Gene name
Itgb1
Definition
(RefSeq) integrin beta-1 precursor
  KO
K05719  integrin beta 1
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04015  Rap1 signaling pathway
rno04145  Phagosome
rno04151  PI3K-Akt signaling pathway
rno04360  Axon guidance
rno04510  Focal adhesion
rno04512  ECM-receptor interaction
rno04514  Cell adhesion molecules
rno04530  Tight junction
rno04611  Platelet activation
rno04670  Leukocyte transendothelial migration
rno04810  Regulation of actin cytoskeleton
rno05100  Bacterial invasion of epithelial cells
rno05133  Pertussis
rno05135  Yersinia infection
rno05140  Leishmaniasis
rno05145  Toxoplasmosis
rno05165  Human papillomavirus infection
rno05200  Pathways in cancer
rno05205  Proteoglycans in cancer
rno05222  Small cell lung cancer
rno05410  Hypertrophic cardiomyopathy
rno05412  Arrhythmogenic right ventricular cardiomyopathy
rno05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    24511 (Itgb1)
   04151 PI3K-Akt signaling pathway
    24511 (Itgb1)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    24511 (Itgb1)
   04514 Cell adhesion molecules
    24511 (Itgb1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    24511 (Itgb1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    24511 (Itgb1)
   04530 Tight junction
    24511 (Itgb1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    24511 (Itgb1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    24511 (Itgb1)
   04670 Leukocyte transendothelial migration
    24511 (Itgb1)
  09158 Development and regeneration
   04360 Axon guidance
    24511 (Itgb1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    24511 (Itgb1)
   05205 Proteoglycans in cancer
    24511 (Itgb1)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    24511 (Itgb1)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    24511 (Itgb1)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    24511 (Itgb1)
   05133 Pertussis
    24511 (Itgb1)
   05100 Bacterial invasion of epithelial cells
    24511 (Itgb1)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    24511 (Itgb1)
   05140 Leishmaniasis
    24511 (Itgb1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    24511 (Itgb1)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    24511 (Itgb1)
   05414 Dilated cardiomyopathy
    24511 (Itgb1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:rno04131]
    24511 (Itgb1)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:rno04147]
    24511 (Itgb1)
   04515 Cell adhesion molecules [BR:rno04515]
    24511 (Itgb1)
   04090 CD molecules [BR:rno04090]
    24511 (Itgb1)
Membrane trafficking [BR:rno04131]
 Endocytosis
  Phagocytosis
   Integrins (complement receptors)
    24511 (Itgb1)
Exosome [BR:rno04147]
 Exosomal proteins
  Proteins found in most exosomes
   24511 (Itgb1)
Cell adhesion molecules [BR:rno04515]
 Integrins
  Integrin beta subunits
   24511 (Itgb1)
CD molecules [BR:rno04090]
 Proteins
  24511 (Itgb1)
SSDB
Motif
Pfam: Integrin_beta Integrin_b_cyt Integrin_B_tail I-EGF_1 PSI_integrin EGF_2
Other DBs
NCBI-GeneID: 24511
NCBI-ProteinID: NP_058718
RGD: 2927
Ensembl: ENSRNOG00000010966
UniProt: P49134 A0A0G2JSK5
Position
19
AA seq 798 aa
MNLQLVFWIGLISLICSVFGQTDKNRCLKANAKSCGECIQAGPNCGWCTNTTFLQEGMPT
SARCDDLEALKKKGCQPSDIENPRGSQTIKKNKNVTNRSKGMAEKLRPEDITQIQPQQLL
LKLRSGEPQKFTLKFKRAEDYPIDLYYLMDLSYSMKDDLENVKSLGTDLMNEMRRITSDF
RIGFGSFVEKTVMPYISTTPAKLRNPCTSEQNCTSPFSYKNVLSLTDRGEFFNELVGQQR
ISGNLDSPEGGFDAIMQVAVCGSLIGWRNVTRLLVFSTDAGFHFAGDGKLGGIVLPNDGQ
CHLENNVYTMSHYYDYPSIAHLVQKLSENNIQTIFAVTEEFQPVYKELKNLIPKSAVGTL
SGNSSNVIQLIIDAYNSLSSEVILENSKLPDGVTINYKSYCKNGVNGTGENGRKCSNISI
GDEVQFEISITANKCPNKESETIKIKPLGFTEEVEVVLQFICKCNCQSHGIPASPKCHEG
NGTFECGACRCNEGRVGRHCECSTDEVNSEDMDAYCRKENSSEICSNNGECVCGQCVCRK
RENTNEIYSGKFCECDNFNCDRSNGLICGGNGVCRCRVCECYPNYTGSACDCSLDTVPCV
ATNGQICNGRGICECGACKCTDPKFQGPTCETCQTCLGVCAEHKECVQCRAFNKGEKKDT
CAQECSHFNLTKVESREKLPQPVQVDPVTHCKEKDIDDCWFYFTYSVNSNGEAHVHVVET
PDCPTGPDIIPIVAGVVAGIVLIGLALLLIWKLLMIIHDRREFAKFEKEKMNAKWDTGEN
PIYKSAVTTVVNPKYEGK
NT seq 2397 nt   +upstreamnt  +downstreamnt
atgaatttgcaactggttttctggattggattgatcagcttgatttgttctgtatttggc
caaacagataaaaatagatgtttaaaagcaaatgccaaatcttgtggagaatgtatacaa
gcagggccaaattgtgggtggtgtacaaatacgacatttttacaagaaggaatgcctact
tctgcacgatgtgatgatttagaagctttgaaaaagaagggttgccaaccaagtgacata
gagaatcccagaggctcccaaactataaagaagaataaaaacgtcaccaatcgcagcaaa
gggatggcagagaagctccggccagaagacattactcagatccaaccacaacagctgctt
ctaaagttgcgatcaggagaaccacagaagtttacattaaaattcaagagggctgaagac
taccctattgatctgtactaccttatggatctctcctactctatgaaagatgatctggag
aatgtgaagagtcttgggacggatctgatgaatgaaatgaggaggattacttcagacttc
cgcattggctttggctcatttgtggagaaaactgtgatgccatacattagtacaacacca
gcaaagctaagaaatccttgtacgagtgaacaaaactgtaccagcccatttagctacaaa
aacgtgcttagtcttactgacagaggagagtttttcaatgaacttgttggtcagcagcgc
atatctggaaacttggactctccagaaggtggctttgatgcaatcatgcaggttgcagtt
tgtgggtcgctgattggctggaggaatgtaacacgactgctggtgttttccacggatgct
gggtttcactttgctggagatgggaaacttggtggtattgttttacccaatgatggccag
tgtcacctggaaaataatgtgtatacaatgagccattactatgattatccttcaattgct
caccttgttcagaaactaagtgaaaataatattcagacgatttttgcagtcactgaagag
ttccagcctgtttacaaggaattgaagaatttgattcctaagtcagcagtgggcacactg
tctggaaactctagtaatgtgatacagctgattatcgatgcctacaattccctttcttca
gaagtcattctggaaaacagcaaattgccagatggagtaacaataaattacaagtcctac
tgcaagaatggagtgaatgggacaggagaaaatggacgaaagtgctctaacatttccatt
ggagatgaggttcaatttgaaattagcataactgctaataaatgtccaaacaaggagtct
gaaacaattaaaattaaacctctgggcttcacagaagaagtagaggtggtccttcagttc
atctgtaagtgtaattgtcaaagccatggcatcccagcaagtcccaagtgccatgaggga
aatgggacatttgagtgtggagcctgcaggtgcaatgagggtcgtgttgggagacactgt
gaatgtagcacagatgaagtgaacagtgaagacatggatgcttactgcagaaaagagaac
agctcagagatctgcagtaacaatggagagtgtgtctgtggacagtgtgtgtgcaggaag
agagagaatacaaatgaaatttactccggcaaattctgcgagtgtgataacttcaactgc
gataggtccaacggcttaatctgtggaggaaatggtgtgtgcaggtgtcgtgtctgtgaa
tgctatcccaactacactggcagtgcatgtgactgttccttggacactgttccatgcgta
gcgacaaatggtcagatctgcaatggccggggcatctgtgaatgtggtgcttgtaagtgc
acagatcccaagttccaagggccaacctgtgagacctgtcagacctgccttggtgtctgt
gcagagcataaagaatgtgttcagtgcagagccttcaataaaggagaaaaaaaagacacg
tgtgcacaggagtgctcccatttcaacctcactaaagtggaaagcagggagaagttgccc
cagcctgtgcaggtggaccctgtgacccactgcaaggagaaggacattgatgactgctgg
ttctatttcacctactcagtgaacagcaacggtgaagctcacgtgcatgttgtggagact
ccagactgtcctactggtcccgacatcatcccaattgtagcaggcgtggttgccggaatt
gttcttattggccttgccttgctgctgatttggaaacttttaatgataattcatgacaga
agggaatttgctaaatttgaaaaggagaaaatgaatgccaagtgggacacgggtgaaaat
cctatttacaagagtgccgtgacaactgtggtcaatccgaagtatgagggaaaatga

KEGG   Rattus norvegicus (rat): 25021
Entry
25021             CDS       T01003                                 

Gene name
Itgam
Definition
(RefSeq) integrin alpha-M precursor
  KO
K06461  integrin alpha M
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04015  Rap1 signaling pathway
rno04145  Phagosome
rno04514  Cell adhesion molecules
rno04610  Complement and coagulation cascades
rno04613  Neutrophil extracellular trap formation
rno04640  Hematopoietic cell lineage
rno04670  Leukocyte transendothelial migration
rno04810  Regulation of actin cytoskeleton
rno05133  Pertussis
rno05134  Legionellosis
rno05140  Leishmaniasis
rno05146  Amoebiasis
rno05150  Staphylococcus aureus infection
rno05152  Tuberculosis
rno05202  Transcriptional misregulation in cancer
rno05221  Acute myeloid leukemia
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    25021 (Itgam)
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecules
    25021 (Itgam)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    25021 (Itgam)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    25021 (Itgam)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    25021 (Itgam)
   04610 Complement and coagulation cascades
    25021 (Itgam)
   04613 Neutrophil extracellular trap formation
    25021 (Itgam)
   04670 Leukocyte transendothelial migration
    25021 (Itgam)
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    25021 (Itgam)
  09162 Cancer: specific types
   05221 Acute myeloid leukemia
    25021 (Itgam)
  09171 Infectious disease: bacterial
   05133 Pertussis
    25021 (Itgam)
   05134 Legionellosis
    25021 (Itgam)
   05150 Staphylococcus aureus infection
    25021 (Itgam)
   05152 Tuberculosis
    25021 (Itgam)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    25021 (Itgam)
   05140 Leishmaniasis
    25021 (Itgam)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:rno04131]
    25021 (Itgam)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:rno04147]
    25021 (Itgam)
   04515 Cell adhesion molecules [BR:rno04515]
    25021 (Itgam)
   04090 CD molecules [BR:rno04090]
    25021 (Itgam)
   00536 Glycosaminoglycan binding proteins [BR:rno00536]
    25021 (Itgam)
Membrane trafficking [BR:rno04131]
 Endocytosis
  Phagocytosis
   Integrins (complement receptors)
    25021 (Itgam)
Exosome [BR:rno04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   25021 (Itgam)
Cell adhesion molecules [BR:rno04515]
 Integrins
  Integrin alpha subunits
   25021 (Itgam)
CD molecules [BR:rno04090]
 Proteins
  25021 (Itgam)
Glycosaminoglycan binding proteins [BR:rno00536]
 Heparan sulfate / Heparin
  Adhesion molecules of cell surface
   25021 (Itgam)
SSDB
Motif
Pfam: VWA Integrin_alpha2 FG-GAP VWA_2 Integrin_alpha FG-GAP_3 FG-GAP_2 DUF3660
Other DBs
NCBI-GeneID: 25021
NCBI-ProteinID: NP_036843
RGD: 2926
Ensembl: ENSRNOG00000019728
UniProt: Q9JI30
Position
1
AA seq 1151 aa
MTLKVLLATVLTLCHGFNLDTENPMTFQENASGFGQSVIQLGETRVVVAAPQEVKAVNQT
GALYQCDYSTNRCDPIPLQVPPEAVNMSLGLSLAATTVPPQLLACGPTVHQNCKENTYVN
GLCYLFGSNLLRKPQQFPEALRGCPQQESNIAFLIDGSGSINTIDFQKMKEFVSTVMDQF
QKSKTLFSLMQYSDEFRTHFTFNDFKRNPDPKSHVRPIRQLNGRTKTASGIRKVVRELFQ
KINGARDNAAKILVVITDGEKFGDPLNYEDVIPEAEEAGIIRYVIGVGNAFHKPQSRREL
DTIASKPAGDHVFQVDNFEALNTIRNQLQEKIFAIEGTQTGSTSSFEHEMSQEGFSAAIT
SNGPLLGSVGSFDWAGGAFLYPSKDKASFINTTRIDSDMNDAYLGYASAVISRNRVQSLV
LGAPRYQHIGLVVMFKQNFGAWEPHTDIKGSQIGSYFGASLCSVDMDADGNTNLILIGAP
HHYEKTRGGQVSVCPLPRGRARWQCEAILHGDQGHPWGRFGAALTVLGDVNGDKLTDVAI
GAPGEQENQGAVYIFHGASVASISTPHSQRIAGARFSPGLQYFGQSLSGGKDLTMDGLMD
LAVGAQGRLLLIRAQPVLRLEATMEFSPKNLARSVFACQEEVVKNKDAGEVRVCLQVRKN
TKDRLREGDIQSTVTYDLALDPGRSVVRAFFDETKNGILRRIRVFGLTQKCETLKLILPD
CVDNSVSPIILRLNYTLVGEPLRSSRDLRPVLAMEAQRIFTAMFPFEKNCGNDTICQDDL
SITVSSTRVNTLVVGDSRDFDVSVTLRNDGEDSYGTKVTCYYPSGLSYRKVSASQNQFSK
KPWRVIAEPSSSEGQGVLKSTIWDINHPIFPANSEVTFNVTFDVDSDASLGNKLLLKVVV
TSENNVSRTDKTESQLELPVKYAIYMVVTSGESSIKYLNFTASEMTSKVIQHQYQFNNLG
QRSFPVSVVFWIPVQINKVTIWDPPQVTFSQNLSSVCRTEQKSPSHSKFQDELERTPVLN
CSVAVCKRIQCDIPSFNSKEIFNVTLQGNLLFDWYIETSHDHLLLVSTAEILFNDSAFAL
LPGQETFVKAQTETKVEPYTVHNPVPLIVGSSVGGLVLLALITAGLYKLGFFKRQYKDMM
NEAGGQDGPPQ
NT seq 3456 nt   +upstreamnt  +downstreamnt
atgactcttaaagttcttctggcgacagtcctaaccttgtgtcatggcttcaatttggac
actgaaaatcccatgaccttccaagagaatgcaagtggcttcgggcagagtgtgatccag
cttggtgaaacccgagtggttgttgcagccccccaggaggtaaaggcggttaaccagaca
ggtgccctctaccagtgtgactacagcacaaaccggtgcgaccccattcccctgcaagta
cctccagaggctgtgaatatgtccttgggcctgtccctggctgctactaccgtccctcca
cagctgctggcttgtggccccacagtacaccagaactgcaaggagaacacttacgtcaat
ggattgtgctacctattcggctccaacctgctgaggaagccccagcagttcccagaggct
ctcagaggatgtcctcagcaggagagcaacattgccttcttgattgacggctccggtagc
atcaacacgatcgactttcagaagatgaaggaatttgtctcaactgtgatggaccagttc
caaaagtctaaaaccttgttctctttgatgcagtactctgatgaattccggactcacttc
accttcaatgatttcaagagaaaccctgacccaaaatcacatgtgagacccataaggcag
ctgaatggaaggacaaaaactgcctcagggatccgtaaagtagtgagagaactgtttcag
aaaatcaatggggcccgggacaatgccgcgaagatcctagttgtcatcacagacggagaa
aagtttggtgaccccctaaattatgaggatgtcattcctgaggcagaggaagcagggatc
attcgctacgttattggggtgggaaacgccttccacaaaccacagtcccgcagagagctt
gacaccatcgcgtctaagccagctggtgatcacgtgttccaagtggacaactttgaagct
ctgaataccattcggaaccagctccaggaaaagatctttgcaattgagggcacccagaca
ggaagtaccagctcctttgagcatgagatgtctcaagaaggctttagcgctgccattacc
tccaacggtcccttgctgggctccgtggggagctttgactgggcaggtggagccttcctg
tatccatcaaaggataaagccagtttcatcaacacaaccagaatagattcagacatgaac
gatgcttacttgggttatgcttctgcagtcatctcgaggaaccgcgtccaaagcttggtt
ttaggggcacctcgatatcagcatatcggcctggtggtgatgttcaagcagaatttcggt
gcctgggagccccacactgatatcaagggcagccagatcggctcttattttggggcctcc
ctctgttctgtggacatggacgctgatggcaataccaacttgatcctcattggggcccct
catcactatgagaagacccgagggggccaggtgtcagtgtgccccttgcctagggggaga
gcacggtggcagtgtgaagctattctccatggcgatcagggccatccatggggtcgcttt
ggggcagcattgacagtgctgggagatgtgaatggagacaaactgacagatgtggccatt
ggggccccaggagagcaggagaatcagggtgctgtctacatttttcatggagcatcagta
gccagcatcagtacccctcacagccagcggatcgcaggcgcccgcttctcccccgggctc
cagtactttgggcagtctctgagtgggggcaaggatctcacaatggacggcctgatggac
ttggctgtgggggcgcaggggcgtcttctgctgatcagagcccagcctgtgctgagactg
gaggcaaccatggaattcagccccaagaatctagcaaggagtgtgtttgcgtgtcaagaa
gaagtagtcaaaaacaaggatgctggggaggtcagagtctgcctccaagtccgcaagaac
accaaggacaggctgcgagaaggagacatccagagcactgtcacttatgacctggcttta
gaccccggccgctcagttgtccgagccttctttgatgaaacaaagaacggcatactcagg
cgcatccgggtctttggattgacacagaaatgtgaaaccctgaagctaattttaccggac
tgtgtggacaactcagtgagtcccatcatcctgcgccttaattacacactggttggggag
cccttgcggtcctctagggaccttcggccagttctggctatggaggctcagaggatcttc
acagctatgtttccctttgagaagaattgtggcaatgacaccatttgccaggatgatctc
agcatcaccgtgagttccacacgcgtgaacactttggtggtgggagactcccgggacttt
gacgtgagtgtgactctgagaaatgatggcgaggattcctatgggaccaaggttacctgc
tattacccatctggcttgtcttaccggaaggtgtcagcaagccagaaccagttctccaag
aagccttggcgtgtgatagctgagcccagttcttctgaagggcaaggggttctgaagagc
accatctgggacataaaccatcccatctttcccgctaattctgaggtcacgtttaatgtc
acatttgatgtggactctgatgcctcccttgggaacaaactgctcctcaaggtcgttgtg
accagtgagaacaacgtgtccaggaccgacaaaactgagtctcagttggagttgcctgtg
aagtacgccatctacatggtcgtcaccagtggtgagagttctatcaaatatctcaacttc
acagcttcagagatgaccagtaaggtcatacagcatcagtaccagttcaacaacctgggc
cagaggagcttccctgtcagcgtggtcttctggatccctgtccagatcaacaaggtgacc
atatgggatcctccccaggtcaccttctcccagaacctctcaagtgtctgtcgcactgag
cagaaatccccctctcactccaagttccaggatgagcttgaaaggaccccagtgctgaac
tgctctgttgcagtctgcaagagaatccagtgtgacatcccttccttcaacagtaaagaa
atattcaacgtcaccctccagggcaatctgctatttgactggtacatcgagacttctcat
gaccacctcctgcttgtgagcactgccgagatcctctttaacgactccgcatttgcccta
cttccggggcaggagacgtttgtgaaggctcagacagagaccaaagtggagccatataca
gttcacaatcctgtaccactcattgtgggcagctccgtcggaggcctggtgctcttggct
ctcatcactgctggcctatacaagcttggctttttcaaacgacagtacaaggacatgatg
aatgaagccggtggccaagatggcccacctcagtaa

KEGG   Rattus norvegicus (rat): 308995
Entry
308995            CDS       T01003                                 

Gene name
Itgal
Definition
(RefSeq) integrin alpha-L precursor
  KO
K05718  integrin alpha L
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04015  Rap1 signaling pathway
rno04514  Cell adhesion molecules
rno04613  Neutrophil extracellular trap formation
rno04650  Natural killer cell mediated cytotoxicity
rno04670  Leukocyte transendothelial migration
rno04810  Regulation of actin cytoskeleton
rno05144  Malaria
rno05150  Staphylococcus aureus infection
rno05166  Human T-cell leukemia virus 1 infection
rno05169  Epstein-Barr virus infection
rno05323  Rheumatoid arthritis
rno05416  Viral myocarditis
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    308995 (Itgal)
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecules
    308995 (Itgal)
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    308995 (Itgal)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    308995 (Itgal)
   04650 Natural killer cell mediated cytotoxicity
    308995 (Itgal)
   04670 Leukocyte transendothelial migration
    308995 (Itgal)
 09160 Human Diseases
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    308995 (Itgal)
   05169 Epstein-Barr virus infection
    308995 (Itgal)
  09171 Infectious disease: bacterial
   05150 Staphylococcus aureus infection
    308995 (Itgal)
  09174 Infectious disease: parasitic
   05144 Malaria
    308995 (Itgal)
  09163 Immune disease
   05323 Rheumatoid arthritis
    308995 (Itgal)
  09166 Cardiovascular disease
   05416 Viral myocarditis
    308995 (Itgal)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:rno04147]
    308995 (Itgal)
   04515 Cell adhesion molecules [BR:rno04515]
    308995 (Itgal)
   04090 CD molecules [BR:rno04090]
    308995 (Itgal)
Exosome [BR:rno04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   308995 (Itgal)
Cell adhesion molecules [BR:rno04515]
 Integrins
  Integrin alpha subunits
   308995 (Itgal)
CD molecules [BR:rno04090]
 Proteins
  308995 (Itgal)
SSDB
Motif
Pfam: Integrin_alpha2 VWA FG-GAP VWA_2 FG-GAP_3 FG-GAP_2 Integrin_alpha
Other DBs
NCBI-GeneID: 308995
NCBI-ProteinID: NP_001029170
RGD: 631424
Ensembl: ENSRNOG00000017980
UniProt: Q3T1L6
Position
1
AA seq 1160 aa
MSFRIPGPRLLLLGLQLFVNAWSYNLDTRHAQSFLTQAGRHFGYQVLQFGDGVVVGAPGE
GNSTGNLYHCHPSSGSCQPVHLGSNHTSKYLGMTMVTDAAKGSLLACDPGLSRTCDQNPY
LSGLCYLFSQSLGKPILQNRPAYQECMKGNVDLVFLFDGSQSLDKKDFEKIVDFMKDVMR
KLSNTSYQFAAVQFSTECKTEFTFLDYIKLNKNPDVLLGNVTPMFLLTNTFRAINYVVTH
VFKEESGARPDATKVLVIITDGEASDNGNIDAAQDITRYIIGIGKHFSTTQKQEKLHIFA
SKPVEEFVKILDTFEKLKDLFTDLQRKIYAIEGTSKQDLASFNMELSSSGISADLSKGHA
VVGAVGAKDWAGGFLDLHEDLEGATFVGQEPLTSDERGGYLGYTVAWLTSRSSRPLLAAG
APRYQHVGQVLLFQAPEAGGHWNQTQKIEGTQIGSYFGGELCSVDLHQDGETDLLLIGAP
LFYGEQRGGRVSVYQRRRSLFEMVSELQGDPGYPLGRFGAAISALTDINGDGLTDVAVGA
PLEEQGAVYIFNGKPGGFSSQSSQRIPGTQVSPGVRWFGRSIHGVKDLGGDRLADVVVGA
EGQVIVLSSRPVVDIVTELSFSPDEIPVHEVECSYSASQEQKEGVKLKVCFQIRPLTSQF
QGRLLANLSYTLQLDGHRTRSRGLFPGGSRELGGNTFVTPDRSCMDFHFHFPICIQDLIS
PINVSLNFSLLEEEGSPRDQKGGRDMQPILRPSIHAVTKEIPFEKNCGEDKKCEADLALS
PPARSGVLRLMSSASLAVEWTLRNLGEDAYWVRLDLDFPRGLSFRKVEMLQPHSQIPVSC
EELTEESSLLTKTLKCNVSSPIFKAGKQMTLQVMFNTLLNSSWGDFVELNGTVHCENENS
SLGKDNSATTRIPVLYPVNILTEDQENSTLYISFTPKGPKTQQVQHIYKVRIQPSAYDHN
MPALEALVEVPQPHSEGPIAHTWTVHTDPLVTCHCEDLKKPTREAEPCLPGVQFRCPIVF
RQETFIRVAGTVELSEKIKASSTLSLCSSLSVSFNSSKHFHLYGSKASKAQVLMKVDMIY
EKEMLHLYVLSGIGGLLLLSLIFLALYKVGFFKRKLKEKMEADGGVPNGSPGEDADPLAV
PGEETKDMGCLEPLRESDKD
NT seq 3483 nt   +upstreamnt  +downstreamnt
atgagtttccggatccctggccccagacttctgctattggggctccagctgtttgtgaat
gcctggagctacaacctggacacgcggcatgcgcagagcttcttgacacaagctggaaga
cattttgggtaccaggtcttgcagtttggagatggggttgtcgtgggagctccaggagag
gggaacagcacaggaaacctctatcactgtcacccaagcagcggctcctgccagccagtc
cacctaggttctaaccatacctccaaatacttgggaatgaccatggtgacagatgctgcc
aagggaagccttttggcctgtgatcctggactgtctcggacctgtgatcagaacccctac
ctcagtgggctgtgctacttattttcccagagcctggggaaacctatattacaaaatcgt
cctgcttatcaggaatgtatgaagggcaatgtcgacctagtgtttctgttcgatggctca
cagagcttggataaaaaggactttgaaaaaatcgtggacttcatgaaggatgtgatgagg
aaactcagcaacacttcctaccagtttgctgctgttcagttttccacagagtgcaaaaca
gaatttactttcttggactacatcaagctaaacaagaatcctgatgttctgctaggcaac
gtgacgcccatgttcttgctgaccaataccttccgtgccatcaactacgtggtgacacac
gtgttcaaagaagagtctggtgccaggccagatgctaccaaggtgcttgtcatcattaca
gacggggaagcaagtgacaatggcaacatcgatgcagcccaagacataacccgctatatc
atcgggattggcaagcatttttcaaccacacaaaagcaggagaaactccacatatttgcc
tcaaaacctgtagaggaatttgtcaagattctggacacatttgagaagctgaaggatctg
tttactgatctgcagaggaagatttatgccattgagggcacaagcaaacaggacctggca
tcctttaatatggaactctcctccagcgggatcagcgcagacctcagcaagggccatgcg
gttgttggagccgttggggctaaggattgggctgggggctttctggacctgcatgaagac
ctggagggtgccacatttgttgggcaggaaccgctgacctcagatgagagaggaggttat
ctgggttacactgtggcctggctgacctcccggagctctagaccactgctggcagcagga
gctccgcggtaccagcatgtgggacaagtgctgcttttccaagccccagaagctggagga
cattggaaccagactcagaagatagaagggactcagatcggatcttactttggtggggag
ctatgtagcgttgacctgcaccaagatggcgagacagatctgctgctgattggagcgccc
ctcttctacggggagcagagaggaggccgagtgtccgtttaccagagaagacggtcactg
ttcgaaatggtctcagagctgcagggtgacccaggctacccgcttggtcggtttggagct
gccataagtgccctgacagacatcaatggggatgggctgactgatgtggccgtgggagcc
cctctggaggagcagggggctgtgtatatcttcaatgggaagcctggtgggttcagttcc
cagtcaagtcagcgtataccaggaacccaggtgtccccgggagtccggtggtttggacgc
tccatccatggggtgaaggaccttggaggggacaggctggcagatgtggttgtaggagct
gagggccaggtgattgtgctgagctcgaggccggtggtggatattgtcactgagctgtcc
ttctccccagacgaaatcccagtgcatgaggtggagtgctcctactcagccagtcaggag
cagaaggaaggcgtcaagctcaaggtgtgcttccagatccgcccccttacgtctcagttt
caaggtcgcctgcttgccaacctcagctacaccctgcagctggacggccatcggacgagg
agccgaggtctgttcccaggaggaagccgtgagctcggcggaaacacatttgtcacccca
gataggtcctgcatggacttccacttccacttcccaatctgcattcaagacctcatctcc
cctatcaatgtctctctgaatttctctcttttggaggaagaaggatcaccaagggaccaa
aaggggggcagggacatgcagcccatcctgagaccttcgatccatgcagtcactaaggag
atcccctttgagaagaactgtggtgaggataagaagtgtgaggcagacctggccctgtca
cctcctgccagatccggagtcctgcgtctgatgtcctctgccagccttgctgtggagtgg
acactgaggaacttgggagaagacgcttactgggtgcgactggacctggacttcccccgg
ggcctctccttccgaaaagtggagatgcttcagccacacagccaaatacctgtgagctgc
gaggagctcaccgaggagtcgagtctcctgactaagaccctgaaatgcaatgtgagctct
cccatcttcaaagcaggcaaacagatgaccctccaggtgatgtttaacacgctactcaac
agttcctggggagattttgtcgagctgaacggcactgtgcactgtgagaacgagaactca
agcctcgggaaggacaactcagccaccacccgcattcctgtcctgtaccctgtcaacatc
cttactgaggaccaggagaactccacactctatatcagtttcacccctaaaggtcccaag
actcaacaagtccagcatatctacaaggtgaggattcagccttctgcctatgaccacaac
atgcccgcactggaggccttggttgaggtgccgcagcctcacagcgagggccccatcgca
cacacatggactgtgcatacggatccccttgtcacttgccactgtgaggacctgaagaag
ccaaccagggaagctgagccctgtctgcctggagtccagttccgctgcccaattgtcttc
aggcaagagaccttcatccgagtggccgggactgtggaactctcagagaaaatcaaggcc
tcctccacactcagcctctgcagctcgctctcagtctccttcaacagcagcaagcatttc
catttgtatggtagcaaggcctccaaggcccaggtcctcatgaaggttgacatgatctat
gagaaggagatgcttcacctgtacgtgctcagcggcattggggggctattgctactgtcc
ctgattttcctagcgctctacaaggttggtttcttcaaacggaagctgaaggagaagatg
gaggcggatggaggtgttccaaatggaagccctggcgaagacgctgaccctctggcagta
cctggggaagagaccaaagatatgggctgtctagagcccctccgtgagagtgacaaggac
taa

KEGG   Rattus norvegicus (rat): 309684
Entry
309684            CDS       T01003                                 

Gene name
Itgb2
Definition
(RefSeq) integrin beta-2 precursor
  KO
K06464  integrin beta 2
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04015  Rap1 signaling pathway
rno04145  Phagosome
rno04390  Hippo signaling pathway
rno04514  Cell adhesion molecules
rno04610  Complement and coagulation cascades
rno04613  Neutrophil extracellular trap formation
rno04650  Natural killer cell mediated cytotoxicity
rno04670  Leukocyte transendothelial migration
rno04810  Regulation of actin cytoskeleton
rno05133  Pertussis
rno05134  Legionellosis
rno05140  Leishmaniasis
rno05144  Malaria
rno05146  Amoebiasis
rno05150  Staphylococcus aureus infection
rno05152  Tuberculosis
rno05166  Human T-cell leukemia virus 1 infection
rno05323  Rheumatoid arthritis
rno05416  Viral myocarditis
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    309684 (Itgb2)
   04390 Hippo signaling pathway
    309684 (Itgb2)
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecules
    309684 (Itgb2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    309684 (Itgb2)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    309684 (Itgb2)
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    309684 (Itgb2)
   04613 Neutrophil extracellular trap formation
    309684 (Itgb2)
   04650 Natural killer cell mediated cytotoxicity
    309684 (Itgb2)
   04670 Leukocyte transendothelial migration
    309684 (Itgb2)
 09160 Human Diseases
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    309684 (Itgb2)
  09171 Infectious disease: bacterial
   05133 Pertussis
    309684 (Itgb2)
   05134 Legionellosis
    309684 (Itgb2)
   05150 Staphylococcus aureus infection
    309684 (Itgb2)
   05152 Tuberculosis
    309684 (Itgb2)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    309684 (Itgb2)
   05144 Malaria
    309684 (Itgb2)
   05140 Leishmaniasis
    309684 (Itgb2)
  09163 Immune disease
   05323 Rheumatoid arthritis
    309684 (Itgb2)
  09166 Cardiovascular disease
   05416 Viral myocarditis
    309684 (Itgb2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:rno04131]
    309684 (Itgb2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:rno04147]
    309684 (Itgb2)
   04515 Cell adhesion molecules [BR:rno04515]
    309684 (Itgb2)
   04090 CD molecules [BR:rno04090]
    309684 (Itgb2)
Membrane trafficking [BR:rno04131]
 Endocytosis
  Phagocytosis
   Integrins (complement receptors)
    309684 (Itgb2)
Exosome [BR:rno04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   309684 (Itgb2)
Cell adhesion molecules [BR:rno04515]
 Integrins
  Integrin beta subunits
   309684 (Itgb2)
CD molecules [BR:rno04090]
 Proteins
  309684 (Itgb2)
SSDB
Motif
Pfam: Integrin_beta Integrin_b_cyt Integrin_B_tail PSI_integrin EGF_2
Other DBs
NCBI-GeneID: 309684
NCBI-ProteinID: NP_001032869
RGD: 1305581
Ensembl: ENSRNOG00000001224
UniProt: B2RYB8
Position
20
AA seq 768 aa
MLGPHTLLLILAGLLFLGSALSEECTKYKVSNCRDCIQSGPGCSWCQKLNFTGPGEPDSL
RCDTRAQLLLKGCPADDIMDPKSFADLHPQYQVQRSQLSPQKVTLNLRPGQAAAFNVTFR
RAKGYPIDLYYLMDLSYSMLDDLNNVKKLGGDLLQALNEITESGRIGFGSFVDKTVLPFV
NTHPEKLRNPCPNKEKACQPPFAFRHVLKLTDNSNQFQTEVGKQLISGNLDAPEGGLDAI
MQVAACPEEIGWRNVTRLLVFATDDGFHFAGDGKLGAILTPNDGRCHLEDNMYKRSNEFD
YPSVGQLAHKLSESNIQPIFAVTKKMVKTYEKLTEIIPKSAVGELSDDSSNVVQLIKKAY
YKLSSRVFLDHTTIPDTLKVTYDSFCNNRVSSIGKSRGDCDGVQINNPVTFQVKVTASEC
IQEQSFVIRALGFTDTVTVQVHPQCECQCRDQSRMRNLCGGKGVMECGICRCESGYIGKN
CECQTQGRSSQELEGNCRKDNSSIVCSGLGDCICGQCVCHTSDIPNKVIFGQYCECDNFN
CERYDGQVCGGLKRGSCSCGQCNCKEGFEGSACQCQRSTTGCLNARLVECSGRGRCQCNR
CICEKGYQPPLCEECPGCPLPCSTYVFCAECLKFDKGPFQKNCSVQCANVTLQTVPFKKK
PCKERDSEGCWITYTLQQKDGNAYNIHVDDDRECVKGPNVAAIIGGTVAGVVLIGVLLLV
IWKALTHLTDLNEYRRFEKEKLKSQWNNDNPLFKSATTTVMNPKFAES
NT seq 2307 nt   +upstreamnt  +downstreamnt
atgctgggcccacacacactgctactcatcctagctggactactcttcctgggatctgcc
ctgtccgaggaatgcaccaagtacaaagtcagcaactgccgggactgtatccagtcgggg
cctggctgctcgtggtgccagaagctgaacttcaccggaccaggggagcctgactccttg
cgctgtgacacgcgggcacagctgctcctcaagggttgcccagccgatgatataatggac
cccaagagctttgctgatctccacccccaatatcaggtgcaacggagtcaactgtctcca
caaaaagtgacccttaacttgcgaccagggcaggctgctgcattcaatgtgactttccga
cgggccaagggctaccccattgatctgtactacctcatggacctctcctactctatgctc
gatgacctgaacaatgtcaagaagttgggtggtgatttgctgcaggccctcaacgagatc
acagagtccggccgcatcggcttcgggtccttcgtggacaagacggtgctgccttttgtc
aacacccatcccgagaagctgaggaacccatgccccaacaaggagaaagcctgccagcct
ccgtttgcctttcgccacgtgctcaagctaaccgacaactccaaccagtttcagacagag
gtcggcaagcaactgatttccggaaacctggacgcccctgagggcgggctggatgccata
atgcaagtggctgcctgtccggaggaaattggctggcgcaatgtcacgaggctgctggtg
tttgccacagacgacggcttccactttgccggtgatgggaaactgggtgccatcctgacc
cccaacgatggccgctgccacctggaggataacatgtacaagaggagcaatgagttcgac
tacccgtcagtgggccagctggcccacaaactttccgagagcaacatccagcccatcttt
gcagtgacaaagaagatggtgaaaacctatgagaaactgacagagattatccccaagtca
gcggtgggcgagctgtctgacgattccagtaacgtagtccagcttatcaagaaagcctac
tacaaactctcctctagagtcttcctggaccacaccaccatcccggacaccctgaaagtc
acctatgactccttctgtaataacagagtatcgagtataggcaaatcccgaggggactgt
gacggtgtgcagatcaacaacccggtcaccttccaggtaaaggtcacggcttcggagtgt
atccaggagcagtcctttgtcatccgggcgctgggcttcaccgacacagtgacggtacag
gtccatccccagtgcgagtgccagtgccgggaccagagtcggatgaggaatctctgtgga
ggcaagggagtcatggagtgtggcatctgcaggtgtgagtctggctacattgggaaaaac
tgtgagtgtcagacgcagggccggagcagccaggagctggaggggaactgccggaaggac
aatagttccattgtgtgctcggggctgggggactgcatctgcgggcagtgcgtgtgccac
acgagtgacatccccaacaaagtgatctttgggcaatactgcgagtgtgacaacttcaac
tgtgagagatatgatggccaagtctgcggtggcctaaagagaggctcctgctcctgtggc
cagtgtaattgcaaggagggtttcgagggttctgcttgccagtgtcagaggtctaccacg
ggctgtctgaacgcacggctggtggagtgcagtggccgtggccggtgccaatgcaacaga
tgcatctgtgagaaaggttaccagccacctctgtgtgaagagtgtcccggctgccccttg
ccctgcagcacctacgtcttctgtgccgagtgcctgaaatttgataagggcccctttcag
aagaattgtagtgttcagtgtgccaatgtgacgctgcagactgtccctttcaagaaaaag
ccctgcaaggagagggactcggagggctgctggataacctacactttgcagcagaaggac
ggaaacgcttacaacatccatgtggacgacgatcgagagtgtgtgaaaggccccaacgtg
gctgccatcatagggggcactgtggccggcgttgtactgattggtgtcctcctcctggtc
atctggaaggctcttacccacctgactgacctcaatgaatacagacgctttgagaaggag
aaactcaagtcccagtggaacaacgacaaccccctcttcaagagcgccacgacaacggtc
atgaaccctaagtttgctgagagctag

DBGET integrated database retrieval system