KEGG   Rattus norvegicus (rat): 24525
Entry
24525             CDS       T01003                                 

Gene name
Kras
Definition
(RefSeq) GTPase KRas
  KO
K07827  GTPase KRas
Organism
rno  Rattus norvegicus (rat)
Pathway
rno01521  EGFR tyrosine kinase inhibitor resistance
rno01522  Endocrine resistance
rno04010  MAPK signaling pathway
rno04012  ErbB signaling pathway
rno04014  Ras signaling pathway
rno04015  Rap1 signaling pathway
rno04062  Chemokine signaling pathway
rno04068  FoxO signaling pathway
rno04071  Sphingolipid signaling pathway
rno04072  Phospholipase D signaling pathway
rno04137  Mitophagy - animal
rno04140  Autophagy - animal
rno04150  mTOR signaling pathway
rno04151  PI3K-Akt signaling pathway
rno04210  Apoptosis
rno04211  Longevity regulating pathway
rno04213  Longevity regulating pathway - multiple species
rno04218  Cellular senescence
rno04360  Axon guidance
rno04370  VEGF signaling pathway
rno04371  Apelin signaling pathway
rno04540  Gap junction
rno04550  Signaling pathways regulating pluripotency of stem cells
rno04625  C-type lectin receptor signaling pathway
rno04650  Natural killer cell mediated cytotoxicity
rno04660  T cell receptor signaling pathway
rno04662  B cell receptor signaling pathway
rno04664  Fc epsilon RI signaling pathway
rno04714  Thermogenesis
rno04720  Long-term potentiation
rno04722  Neurotrophin signaling pathway
rno04725  Cholinergic synapse
rno04726  Serotonergic synapse
rno04730  Long-term depression
rno04810  Regulation of actin cytoskeleton
rno04910  Insulin signaling pathway
rno04912  GnRH signaling pathway
rno04914  Progesterone-mediated oocyte maturation
rno04915  Estrogen signaling pathway
rno04916  Melanogenesis
rno04917  Prolactin signaling pathway
rno04919  Thyroid hormone signaling pathway
rno04921  Oxytocin signaling pathway
rno04926  Relaxin signaling pathway
rno04929  GnRH secretion
rno04933  AGE-RAGE signaling pathway in diabetic complications
rno04935  Growth hormone synthesis, secretion and action
rno04960  Aldosterone-regulated sodium reabsorption
rno05010  Alzheimer disease
rno05022  Pathways of neurodegeneration - multiple diseases
rno05034  Alcoholism
rno05160  Hepatitis C
rno05161  Hepatitis B
rno05163  Human cytomegalovirus infection
rno05165  Human papillomavirus infection
rno05166  Human T-cell leukemia virus 1 infection
rno05167  Kaposi sarcoma-associated herpesvirus infection
rno05170  Human immunodeficiency virus 1 infection
rno05200  Pathways in cancer
rno05203  Viral carcinogenesis
rno05205  Proteoglycans in cancer
rno05206  MicroRNAs in cancer
rno05210  Colorectal cancer
rno05211  Renal cell carcinoma
rno05212  Pancreatic cancer
rno05213  Endometrial cancer
rno05214  Glioma
rno05215  Prostate cancer
rno05216  Thyroid cancer
rno05218  Melanoma
rno05219  Bladder cancer
rno05220  Chronic myeloid leukemia
rno05221  Acute myeloid leukemia
rno05223  Non-small cell lung cancer
rno05224  Breast cancer
rno05225  Hepatocellular carcinoma
rno05226  Gastric cancer
rno05230  Central carbon metabolism in cancer
rno05231  Choline metabolism in cancer
rno05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
rno05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    24525 (Kras)
   04012 ErbB signaling pathway
    24525 (Kras)
   04014 Ras signaling pathway
    24525 (Kras)
   04015 Rap1 signaling pathway
    24525 (Kras)
   04370 VEGF signaling pathway
    24525 (Kras)
   04371 Apelin signaling pathway
    24525 (Kras)
   04068 FoxO signaling pathway
    24525 (Kras)
   04072 Phospholipase D signaling pathway
    24525 (Kras)
   04071 Sphingolipid signaling pathway
    24525 (Kras)
   04151 PI3K-Akt signaling pathway
    24525 (Kras)
   04150 mTOR signaling pathway
    24525 (Kras)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    24525 (Kras)
   04137 Mitophagy - animal
    24525 (Kras)
  09143 Cell growth and death
   04210 Apoptosis
    24525 (Kras)
   04218 Cellular senescence
    24525 (Kras)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    24525 (Kras)
   04550 Signaling pathways regulating pluripotency of stem cells
    24525 (Kras)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    24525 (Kras)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    24525 (Kras)
   04650 Natural killer cell mediated cytotoxicity
    24525 (Kras)
   04660 T cell receptor signaling pathway
    24525 (Kras)
   04662 B cell receptor signaling pathway
    24525 (Kras)
   04664 Fc epsilon RI signaling pathway
    24525 (Kras)
   04062 Chemokine signaling pathway
    24525 (Kras)
  09152 Endocrine system
   04910 Insulin signaling pathway
    24525 (Kras)
   04929 GnRH secretion
    24525 (Kras)
   04912 GnRH signaling pathway
    24525 (Kras)
   04915 Estrogen signaling pathway
    24525 (Kras)
   04914 Progesterone-mediated oocyte maturation
    24525 (Kras)
   04917 Prolactin signaling pathway
    24525 (Kras)
   04921 Oxytocin signaling pathway
    24525 (Kras)
   04926 Relaxin signaling pathway
    24525 (Kras)
   04935 Growth hormone synthesis, secretion and action
    24525 (Kras)
   04919 Thyroid hormone signaling pathway
    24525 (Kras)
   04916 Melanogenesis
    24525 (Kras)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    24525 (Kras)
  09156 Nervous system
   04725 Cholinergic synapse
    24525 (Kras)
   04726 Serotonergic synapse
    24525 (Kras)
   04720 Long-term potentiation
    24525 (Kras)
   04730 Long-term depression
    24525 (Kras)
   04722 Neurotrophin signaling pathway
    24525 (Kras)
  09158 Development and regeneration
   04360 Axon guidance
    24525 (Kras)
  09149 Aging
   04211 Longevity regulating pathway
    24525 (Kras)
   04213 Longevity regulating pathway - multiple species
    24525 (Kras)
  09159 Environmental adaptation
   04714 Thermogenesis
    24525 (Kras)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    24525 (Kras)
   05206 MicroRNAs in cancer
    24525 (Kras)
   05205 Proteoglycans in cancer
    24525 (Kras)
   05203 Viral carcinogenesis
    24525 (Kras)
   05230 Central carbon metabolism in cancer
    24525 (Kras)
   05231 Choline metabolism in cancer
    24525 (Kras)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    24525 (Kras)
  09162 Cancer: specific types
   05210 Colorectal cancer
    24525 (Kras)
   05212 Pancreatic cancer
    24525 (Kras)
   05225 Hepatocellular carcinoma
    24525 (Kras)
   05226 Gastric cancer
    24525 (Kras)
   05214 Glioma
    24525 (Kras)
   05216 Thyroid cancer
    24525 (Kras)
   05221 Acute myeloid leukemia
    24525 (Kras)
   05220 Chronic myeloid leukemia
    24525 (Kras)
   05218 Melanoma
    24525 (Kras)
   05211 Renal cell carcinoma
    24525 (Kras)
   05219 Bladder cancer
    24525 (Kras)
   05215 Prostate cancer
    24525 (Kras)
   05213 Endometrial cancer
    24525 (Kras)
   05224 Breast cancer
    24525 (Kras)
   05223 Non-small cell lung cancer
    24525 (Kras)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    24525 (Kras)
   05170 Human immunodeficiency virus 1 infection
    24525 (Kras)
   05161 Hepatitis B
    24525 (Kras)
   05160 Hepatitis C
    24525 (Kras)
   05163 Human cytomegalovirus infection
    24525 (Kras)
   05167 Kaposi sarcoma-associated herpesvirus infection
    24525 (Kras)
   05165 Human papillomavirus infection
    24525 (Kras)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    24525 (Kras)
   05022 Pathways of neurodegeneration - multiple diseases
    24525 (Kras)
  09165 Substance dependence
   05034 Alcoholism
    24525 (Kras)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    24525 (Kras)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    24525 (Kras)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    24525 (Kras)
   01522 Endocrine resistance
    24525 (Kras)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:rno04131]
    24525 (Kras)
  09183 Protein families: signaling and cellular processes
   04031 GTP-binding proteins [BR:rno04031]
    24525 (Kras)
Membrane trafficking [BR:rno04131]
 Endocytosis
  Macropinocytosis
   Ras GTPases
    24525 (Kras)
GTP-binding proteins [BR:rno04031]
 Small (monomeric) G-proteins
  Ras Family
   Ras [OT]
    24525 (Kras)
SSDB
Motif
Pfam: Ras Roc Arf GTP_EFTU RsgA_GTPase MMR_HSR1 MeaB FeoB_N G-alpha Gtr1_RagA ATP_bind_1 Septin ParA TPP_enzyme_M CbiA
Other DBs
NCBI-GeneID: 24525
NCBI-ProteinID: NP_113703
RGD: 2981
Ensembl: ENSRNOG00000009338
UniProt: P08644 A0JN17
Position
4
AA seq 188 aa
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG
QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDL
PSRTVDTKQAQELARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEKMSKDGKKKKKK
SRTRCIVM
NT seq 567 nt   +upstreamnt  +downstreamnt
atgactgagtataaacttgtggtagttggagctggtggcgtaggcaagagtgccttgacg
atacagctaattcagaatcactttgtggatgaatatgatcctacgatagaggactcctac
aggaaacaagtagtaattgatggagaaacctgtctcttggatattctcgacacagcaggt
caagaggagtacagtgcaatgagggaccagtacatgagaactggggagggctttctttgt
gtatttgccataaataatactaaatcatttgaagatattcaccattatagagaacaaatt
aaaagagtaaaggactctgaagatgtgcctatggtcctagtagggaataagtgtgacttg
ccttctagaacagtagacacgaaacaggctcaggagttagcaaggagttatgggattcca
ttcattgagacctcagcgaagacaagacagggtgttgacgatgccttctatacattagtc
cgagaaattcgaaaacataaagaaaagatgagcaaagatgggaaaaagaagaagaagaag
tcaaggacaaggtgtatagtcatgtga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (81)   
   KEGG PATHWAY (81)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (7)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (14)   
   RefSeq(nuc) (4)   
   GenBank (5)   
   EMBL (5)   
Protein domain (15)   
   Pfam (15)   
All databases (127)   

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KEGG   Rattus norvegicus (rat): 24605
Entry
24605             CDS       T01003                                 

Gene name
Nras
Definition
(RefSeq) GTPase NRas
  KO
K07828  GTPase NRas
Organism
rno  Rattus norvegicus (rat)
Pathway
rno01521  EGFR tyrosine kinase inhibitor resistance
rno01522  Endocrine resistance
rno04010  MAPK signaling pathway
rno04012  ErbB signaling pathway
rno04014  Ras signaling pathway
rno04015  Rap1 signaling pathway
rno04062  Chemokine signaling pathway
rno04068  FoxO signaling pathway
rno04071  Sphingolipid signaling pathway
rno04072  Phospholipase D signaling pathway
rno04137  Mitophagy - animal
rno04140  Autophagy - animal
rno04150  mTOR signaling pathway
rno04151  PI3K-Akt signaling pathway
rno04210  Apoptosis
rno04211  Longevity regulating pathway
rno04213  Longevity regulating pathway - multiple species
rno04218  Cellular senescence
rno04360  Axon guidance
rno04370  VEGF signaling pathway
rno04371  Apelin signaling pathway
rno04540  Gap junction
rno04550  Signaling pathways regulating pluripotency of stem cells
rno04625  C-type lectin receptor signaling pathway
rno04650  Natural killer cell mediated cytotoxicity
rno04660  T cell receptor signaling pathway
rno04662  B cell receptor signaling pathway
rno04664  Fc epsilon RI signaling pathway
rno04714  Thermogenesis
rno04720  Long-term potentiation
rno04722  Neurotrophin signaling pathway
rno04725  Cholinergic synapse
rno04726  Serotonergic synapse
rno04730  Long-term depression
rno04810  Regulation of actin cytoskeleton
rno04910  Insulin signaling pathway
rno04912  GnRH signaling pathway
rno04915  Estrogen signaling pathway
rno04916  Melanogenesis
rno04917  Prolactin signaling pathway
rno04919  Thyroid hormone signaling pathway
rno04921  Oxytocin signaling pathway
rno04926  Relaxin signaling pathway
rno04929  GnRH secretion
rno04933  AGE-RAGE signaling pathway in diabetic complications
rno04935  Growth hormone synthesis, secretion and action
rno05010  Alzheimer disease
rno05022  Pathways of neurodegeneration - multiple diseases
rno05034  Alcoholism
rno05160  Hepatitis C
rno05161  Hepatitis B
rno05163  Human cytomegalovirus infection
rno05165  Human papillomavirus infection
rno05166  Human T-cell leukemia virus 1 infection
rno05167  Kaposi sarcoma-associated herpesvirus infection
rno05170  Human immunodeficiency virus 1 infection
rno05200  Pathways in cancer
rno05203  Viral carcinogenesis
rno05205  Proteoglycans in cancer
rno05206  MicroRNAs in cancer
rno05210  Colorectal cancer
rno05211  Renal cell carcinoma
rno05213  Endometrial cancer
rno05214  Glioma
rno05215  Prostate cancer
rno05216  Thyroid cancer
rno05218  Melanoma
rno05219  Bladder cancer
rno05220  Chronic myeloid leukemia
rno05221  Acute myeloid leukemia
rno05223  Non-small cell lung cancer
rno05224  Breast cancer
rno05225  Hepatocellular carcinoma
rno05226  Gastric cancer
rno05230  Central carbon metabolism in cancer
rno05231  Choline metabolism in cancer
rno05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
rno05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    24605 (Nras)
   04012 ErbB signaling pathway
    24605 (Nras)
   04014 Ras signaling pathway
    24605 (Nras)
   04015 Rap1 signaling pathway
    24605 (Nras)
   04370 VEGF signaling pathway
    24605 (Nras)
   04371 Apelin signaling pathway
    24605 (Nras)
   04068 FoxO signaling pathway
    24605 (Nras)
   04072 Phospholipase D signaling pathway
    24605 (Nras)
   04071 Sphingolipid signaling pathway
    24605 (Nras)
   04151 PI3K-Akt signaling pathway
    24605 (Nras)
   04150 mTOR signaling pathway
    24605 (Nras)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    24605 (Nras)
   04137 Mitophagy - animal
    24605 (Nras)
  09143 Cell growth and death
   04210 Apoptosis
    24605 (Nras)
   04218 Cellular senescence
    24605 (Nras)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    24605 (Nras)
   04550 Signaling pathways regulating pluripotency of stem cells
    24605 (Nras)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    24605 (Nras)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    24605 (Nras)
   04650 Natural killer cell mediated cytotoxicity
    24605 (Nras)
   04660 T cell receptor signaling pathway
    24605 (Nras)
   04662 B cell receptor signaling pathway
    24605 (Nras)
   04664 Fc epsilon RI signaling pathway
    24605 (Nras)
   04062 Chemokine signaling pathway
    24605 (Nras)
  09152 Endocrine system
   04910 Insulin signaling pathway
    24605 (Nras)
   04929 GnRH secretion
    24605 (Nras)
   04912 GnRH signaling pathway
    24605 (Nras)
   04915 Estrogen signaling pathway
    24605 (Nras)
   04917 Prolactin signaling pathway
    24605 (Nras)
   04921 Oxytocin signaling pathway
    24605 (Nras)
   04926 Relaxin signaling pathway
    24605 (Nras)
   04935 Growth hormone synthesis, secretion and action
    24605 (Nras)
   04919 Thyroid hormone signaling pathway
    24605 (Nras)
   04916 Melanogenesis
    24605 (Nras)
  09156 Nervous system
   04725 Cholinergic synapse
    24605 (Nras)
   04726 Serotonergic synapse
    24605 (Nras)
   04720 Long-term potentiation
    24605 (Nras)
   04730 Long-term depression
    24605 (Nras)
   04722 Neurotrophin signaling pathway
    24605 (Nras)
  09158 Development and regeneration
   04360 Axon guidance
    24605 (Nras)
  09149 Aging
   04211 Longevity regulating pathway
    24605 (Nras)
   04213 Longevity regulating pathway - multiple species
    24605 (Nras)
  09159 Environmental adaptation
   04714 Thermogenesis
    24605 (Nras)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    24605 (Nras)
   05206 MicroRNAs in cancer
    24605 (Nras)
   05205 Proteoglycans in cancer
    24605 (Nras)
   05203 Viral carcinogenesis
    24605 (Nras)
   05230 Central carbon metabolism in cancer
    24605 (Nras)
   05231 Choline metabolism in cancer
    24605 (Nras)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    24605 (Nras)
  09162 Cancer: specific types
   05210 Colorectal cancer
    24605 (Nras)
   05225 Hepatocellular carcinoma
    24605 (Nras)
   05226 Gastric cancer
    24605 (Nras)
   05214 Glioma
    24605 (Nras)
   05216 Thyroid cancer
    24605 (Nras)
   05221 Acute myeloid leukemia
    24605 (Nras)
   05220 Chronic myeloid leukemia
    24605 (Nras)
   05218 Melanoma
    24605 (Nras)
   05211 Renal cell carcinoma
    24605 (Nras)
   05219 Bladder cancer
    24605 (Nras)
   05215 Prostate cancer
    24605 (Nras)
   05213 Endometrial cancer
    24605 (Nras)
   05224 Breast cancer
    24605 (Nras)
   05223 Non-small cell lung cancer
    24605 (Nras)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    24605 (Nras)
   05170 Human immunodeficiency virus 1 infection
    24605 (Nras)
   05161 Hepatitis B
    24605 (Nras)
   05160 Hepatitis C
    24605 (Nras)
   05163 Human cytomegalovirus infection
    24605 (Nras)
   05167 Kaposi sarcoma-associated herpesvirus infection
    24605 (Nras)
   05165 Human papillomavirus infection
    24605 (Nras)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    24605 (Nras)
   05022 Pathways of neurodegeneration - multiple diseases
    24605 (Nras)
  09165 Substance dependence
   05034 Alcoholism
    24605 (Nras)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    24605 (Nras)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    24605 (Nras)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    24605 (Nras)
   01522 Endocrine resistance
    24605 (Nras)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:rno04131]
    24605 (Nras)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:rno04147]
    24605 (Nras)
   04031 GTP-binding proteins [BR:rno04031]
    24605 (Nras)
Membrane trafficking [BR:rno04131]
 Endocytosis
  Macropinocytosis
   Ras GTPases
    24605 (Nras)
Exosome [BR:rno04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   24605 (Nras)
  Exosomal proteins of other body fluids (saliva and urine)
   24605 (Nras)
  Exosomal proteins of breast cancer cells
   24605 (Nras)
  Exosomal proteins of colorectal cancer cells
   24605 (Nras)
GTP-binding proteins [BR:rno04031]
 Small (monomeric) G-proteins
  Ras Family
   Ras [OT]
    24605 (Nras)
SSDB
Motif
Pfam: Ras Roc Arf GTP_EFTU RsgA_GTPase MMR_HSR1 FeoB_N Septin ParA Ldh_1_N CbiA
Other DBs
NCBI-GeneID: 24605
NCBI-ProteinID: NP_542944
RGD: 3205
Ensembl: ENSRNOG00000023079
UniProt: Q04970
Position
2
AA seq 189 aa
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG
QEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDL
PTRTVDTKQAHELAKSYGIPFIETSAKTRQGVEDAFYTLVREIRQYRMKKLNSSEDGTQG
CMGLPCVVM
NT seq 570 nt   +upstreamnt  +downstreamnt
atgactgagtacaaactggtggtggttggagcaggtggcgttgggaaaagtgctttgaca
atccagctaatccagaaccactttgtggatgaatatgatcccaccatagaggattcttac
cgaaaacaagtggtgattgacggtgagacctgtctactggacatactggacacagctgga
caagaggagtacagtgccatgagagaccaatacatgaggacaggcgaagggttcctctgt
gtgtttgccatcaataatagcaaatcctttgcagatattaacctctacagggagcaaatt
aagcgcgtgaaagactctgatgatgtacccatggtgctggtagggaacaagtgtgacttg
ccaacaaggacagttgacacaaagcaagcccacgagctggccaagagttatggaattcca
ttcattgaaacctcagccaagacccgacagggtgtggaggatgccttttacacgcttgta
agggagatacgccagtaccggatgaagaagctcaacagcagtgaggatggcactcaaggc
tgtatggggctgccctgtgtggtgatgtag

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (78)   
   KEGG PATHWAY (78)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (4)   
   RefSeq(nuc) (2)   
   GenBank (1)   
   EMBL (1)   
Protein domain (11)   
   Pfam (11)   
All databases (108)   

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KEGG   Rattus norvegicus (rat): 25482
Entry
25482             CDS       T01003                                 

Gene name
Mras
Definition
(RefSeq) ras-related protein M-Ras
  KO
K07831  Ras-related protein M-Ras
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04010  MAPK signaling pathway
rno04014  Ras signaling pathway
rno04015  Rap1 signaling pathway
rno04072  Phospholipase D signaling pathway
rno04137  Mitophagy - animal
rno04140  Autophagy - animal
rno04218  Cellular senescence
rno04371  Apelin signaling pathway
rno04625  C-type lectin receptor signaling pathway
rno04810  Regulation of actin cytoskeleton
rno05205  Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    25482 (Mras)
   04014 Ras signaling pathway
    25482 (Mras)
   04015 Rap1 signaling pathway
    25482 (Mras)
   04371 Apelin signaling pathway
    25482 (Mras)
   04072 Phospholipase D signaling pathway
    25482 (Mras)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    25482 (Mras)
   04137 Mitophagy - animal
    25482 (Mras)
  09143 Cell growth and death
   04218 Cellular senescence
    25482 (Mras)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    25482 (Mras)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    25482 (Mras)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    25482 (Mras)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04031 GTP-binding proteins [BR:rno04031]
    25482 (Mras)
GTP-binding proteins [BR:rno04031]
 Small (monomeric) G-proteins
  Ras Family
   Ras [OT]
    25482 (Mras)
SSDB
Motif
Pfam: Ras Roc GTP_EFTU Arf RsgA_GTPase MMR_HSR1 ATP_bind_1 FeoB_N AAA_16
Other DBs
NCBI-GeneID: 25482
NCBI-ProteinID: NP_001375430
RGD: 3111
Ensembl: ENSRNOG00000014060
Position
8
AA seq 208 aa
MATSAVPSDNLPTYKLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQW
AILDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFP
MILVANKVDLMHLRKITRDQGKEMATKYNIPYIETSAKDPPLNVDKTFHDLVRVIRQQVP
EKNQKKKKKTKWRGDRATGTHKLQCVIL
NT seq 627 nt   +upstreamnt  +downstreamnt
atggcgaccagcgctgttcccagtgacaaccttcccacatataaactggtagtggtggga
gatggcggtgtgggcaagagtgctctcactattcagtttttccagaagatcttcgtgcct
gactacgaccccaccattgaagactcctacctgaagcatacagagatcgacaatcaatgg
gccatcttggacgttctggacacagctgggcaggaggagttcagtgccatgcgggagcaa
tacatgcgcacaggggatggcttcctcattgtctactctgtcaccgacaaggccagcttc
gagcacgtggaccgcttccaccagctcattctgcgtgtcaaggacagggagtcattccca
atgatcctcgtggccaacaaagtggacctgatgcacctaaggaaaatcaccagggaccaa
ggaaaagaaatggcgaccaaatacaatatcccatatatagaaaccagtgccaaggacccg
cctctcaacgtggacaaaaccttccatgacctagttagagtaattaggcaacaggttcca
gagaaaaaccagaagaagaaaaagaagacaaaatggcgaggggacagggccaccggcact
cacaaactacagtgtgtcatcttgtga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (11)   
   KEGG PATHWAY (11)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (7)   
   UniProt (1)   
   RefSeq(pep) (6)   
DNA sequence (10)   
   RefSeq(nuc) (6)   
   GenBank (2)   
   EMBL (2)   
Protein domain (9)   
   Pfam (9)   
All databases (46)   

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KEGG   Rattus norvegicus (rat): 293621
Entry
293621            CDS       T01003                                 

Gene name
Hras
Definition
(RefSeq) GTPase HRas
  KO
K02833  GTPase HRas
Organism
rno  Rattus norvegicus (rat)
Pathway
rno01521  EGFR tyrosine kinase inhibitor resistance
rno01522  Endocrine resistance
rno04010  MAPK signaling pathway
rno04012  ErbB signaling pathway
rno04014  Ras signaling pathway
rno04015  Rap1 signaling pathway
rno04062  Chemokine signaling pathway
rno04068  FoxO signaling pathway
rno04071  Sphingolipid signaling pathway
rno04072  Phospholipase D signaling pathway
rno04137  Mitophagy - animal
rno04140  Autophagy - animal
rno04144  Endocytosis
rno04150  mTOR signaling pathway
rno04151  PI3K-Akt signaling pathway
rno04210  Apoptosis
rno04211  Longevity regulating pathway
rno04213  Longevity regulating pathway - multiple species
rno04218  Cellular senescence
rno04360  Axon guidance
rno04370  VEGF signaling pathway
rno04371  Apelin signaling pathway
rno04510  Focal adhesion
rno04540  Gap junction
rno04550  Signaling pathways regulating pluripotency of stem cells
rno04625  C-type lectin receptor signaling pathway
rno04630  JAK-STAT signaling pathway
rno04650  Natural killer cell mediated cytotoxicity
rno04660  T cell receptor signaling pathway
rno04662  B cell receptor signaling pathway
rno04664  Fc epsilon RI signaling pathway
rno04714  Thermogenesis
rno04720  Long-term potentiation
rno04722  Neurotrophin signaling pathway
rno04725  Cholinergic synapse
rno04726  Serotonergic synapse
rno04730  Long-term depression
rno04810  Regulation of actin cytoskeleton
rno04910  Insulin signaling pathway
rno04912  GnRH signaling pathway
rno04915  Estrogen signaling pathway
rno04916  Melanogenesis
rno04917  Prolactin signaling pathway
rno04919  Thyroid hormone signaling pathway
rno04921  Oxytocin signaling pathway
rno04926  Relaxin signaling pathway
rno04929  GnRH secretion
rno04933  AGE-RAGE signaling pathway in diabetic complications
rno04935  Growth hormone synthesis, secretion and action
rno05010  Alzheimer disease
rno05022  Pathways of neurodegeneration - multiple diseases
rno05034  Alcoholism
rno05132  Salmonella infection
rno05160  Hepatitis C
rno05161  Hepatitis B
rno05163  Human cytomegalovirus infection
rno05165  Human papillomavirus infection
rno05166  Human T-cell leukemia virus 1 infection
rno05167  Kaposi sarcoma-associated herpesvirus infection
rno05170  Human immunodeficiency virus 1 infection
rno05200  Pathways in cancer
rno05203  Viral carcinogenesis
rno05205  Proteoglycans in cancer
rno05206  MicroRNAs in cancer
rno05210  Colorectal cancer
rno05211  Renal cell carcinoma
rno05213  Endometrial cancer
rno05214  Glioma
rno05215  Prostate cancer
rno05216  Thyroid cancer
rno05218  Melanoma
rno05219  Bladder cancer
rno05220  Chronic myeloid leukemia
rno05221  Acute myeloid leukemia
rno05223  Non-small cell lung cancer
rno05224  Breast cancer
rno05225  Hepatocellular carcinoma
rno05226  Gastric cancer
rno05230  Central carbon metabolism in cancer
rno05231  Choline metabolism in cancer
rno05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
rno05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    293621 (Hras)
   04012 ErbB signaling pathway
    293621 (Hras)
   04014 Ras signaling pathway
    293621 (Hras)
   04015 Rap1 signaling pathway
    293621 (Hras)
   04370 VEGF signaling pathway
    293621 (Hras)
   04371 Apelin signaling pathway
    293621 (Hras)
   04630 JAK-STAT signaling pathway
    293621 (Hras)
   04068 FoxO signaling pathway
    293621 (Hras)
   04072 Phospholipase D signaling pathway
    293621 (Hras)
   04071 Sphingolipid signaling pathway
    293621 (Hras)
   04151 PI3K-Akt signaling pathway
    293621 (Hras)
   04150 mTOR signaling pathway
    293621 (Hras)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    293621 (Hras)
   04140 Autophagy - animal
    293621 (Hras)
   04137 Mitophagy - animal
    293621 (Hras)
  09143 Cell growth and death
   04210 Apoptosis
    293621 (Hras)
   04218 Cellular senescence
    293621 (Hras)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    293621 (Hras)
   04540 Gap junction
    293621 (Hras)
   04550 Signaling pathways regulating pluripotency of stem cells
    293621 (Hras)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    293621 (Hras)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    293621 (Hras)
   04650 Natural killer cell mediated cytotoxicity
    293621 (Hras)
   04660 T cell receptor signaling pathway
    293621 (Hras)
   04662 B cell receptor signaling pathway
    293621 (Hras)
   04664 Fc epsilon RI signaling pathway
    293621 (Hras)
   04062 Chemokine signaling pathway
    293621 (Hras)
  09152 Endocrine system
   04910 Insulin signaling pathway
    293621 (Hras)
   04929 GnRH secretion
    293621 (Hras)
   04912 GnRH signaling pathway
    293621 (Hras)
   04915 Estrogen signaling pathway
    293621 (Hras)
   04917 Prolactin signaling pathway
    293621 (Hras)
   04921 Oxytocin signaling pathway
    293621 (Hras)
   04926 Relaxin signaling pathway
    293621 (Hras)
   04935 Growth hormone synthesis, secretion and action
    293621 (Hras)
   04919 Thyroid hormone signaling pathway
    293621 (Hras)
   04916 Melanogenesis
    293621 (Hras)
  09156 Nervous system
   04725 Cholinergic synapse
    293621 (Hras)
   04726 Serotonergic synapse
    293621 (Hras)
   04720 Long-term potentiation
    293621 (Hras)
   04730 Long-term depression
    293621 (Hras)
   04722 Neurotrophin signaling pathway
    293621 (Hras)
  09158 Development and regeneration
   04360 Axon guidance
    293621 (Hras)
  09149 Aging
   04211 Longevity regulating pathway
    293621 (Hras)
   04213 Longevity regulating pathway - multiple species
    293621 (Hras)
  09159 Environmental adaptation
   04714 Thermogenesis
    293621 (Hras)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    293621 (Hras)
   05206 MicroRNAs in cancer
    293621 (Hras)
   05205 Proteoglycans in cancer
    293621 (Hras)
   05203 Viral carcinogenesis
    293621 (Hras)
   05230 Central carbon metabolism in cancer
    293621 (Hras)
   05231 Choline metabolism in cancer
    293621 (Hras)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    293621 (Hras)
  09162 Cancer: specific types
   05210 Colorectal cancer
    293621 (Hras)
   05225 Hepatocellular carcinoma
    293621 (Hras)
   05226 Gastric cancer
    293621 (Hras)
   05214 Glioma
    293621 (Hras)
   05216 Thyroid cancer
    293621 (Hras)
   05221 Acute myeloid leukemia
    293621 (Hras)
   05220 Chronic myeloid leukemia
    293621 (Hras)
   05218 Melanoma
    293621 (Hras)
   05211 Renal cell carcinoma
    293621 (Hras)
   05219 Bladder cancer
    293621 (Hras)
   05215 Prostate cancer
    293621 (Hras)
   05213 Endometrial cancer
    293621 (Hras)
   05224 Breast cancer
    293621 (Hras)
   05223 Non-small cell lung cancer
    293621 (Hras)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    293621 (Hras)
   05170 Human immunodeficiency virus 1 infection
    293621 (Hras)
   05161 Hepatitis B
    293621 (Hras)
   05160 Hepatitis C
    293621 (Hras)
   05163 Human cytomegalovirus infection
    293621 (Hras)
   05167 Kaposi sarcoma-associated herpesvirus infection
    293621 (Hras)
   05165 Human papillomavirus infection
    293621 (Hras)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    293621 (Hras)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    293621 (Hras)
   05022 Pathways of neurodegeneration - multiple diseases
    293621 (Hras)
  09165 Substance dependence
   05034 Alcoholism
    293621 (Hras)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    293621 (Hras)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    293621 (Hras)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    293621 (Hras)
   01522 Endocrine resistance
    293621 (Hras)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:rno04131]
    293621 (Hras)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:rno04147]
    293621 (Hras)
   04031 GTP-binding proteins [BR:rno04031]
    293621 (Hras)
Membrane trafficking [BR:rno04131]
 Endocytosis
  Macropinocytosis
   Ras GTPases
    293621 (Hras)
Exosome [BR:rno04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   293621 (Hras)
  Exosomal proteins of colorectal cancer cells
   293621 (Hras)
GTP-binding proteins [BR:rno04031]
 Small (monomeric) G-proteins
  Ras Family
   Ras [OT]
    293621 (Hras)
SSDB
Motif
Pfam: Ras Roc Arf GTP_EFTU RsgA_GTPase MMR_HSR1 FeoB_N Gtr1_RagA G-alpha ATP_bind_1 Septin Ldh_1_N AAA_16
Other DBs
NCBI-GeneID: 293621
NCBI-ProteinID: NP_001091711
RGD: 2827
Ensembl: ENSRNOG00000016611
UniProt: P20171
Structure
PDB: 
3V4F

Position
1
AA seq 189 aa
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG
QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL
AARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHKLRKLNPPDESGPG
CMSCKCVLS
NT seq 570 nt   +upstreamnt  +downstreamnt
atgacagaatacaagcttgtggtggtgggcgctggaggcgtgggaaagagtgccctgacc
atccagctgatccagaaccattttgtggacgagtatgatcccactatagaggactcctac
cggaaacaggtagtcattgatggggagacgtgtttactggacatcttagacacagcaggt
caagaagagtatagtgccatgcgggaccagtacatgcgcacaggggagggcttcctctgt
gtatttgccatcaacaacaccaagtcctttgaagacatccatcagtacagggagcagatc
aagcgggtgaaagattcagatgatgtgccaatggtgctggtgggcaacaagtgtgacctg
gccgctcgcactgttgagtctcggcaggcccaggaccttgctcgcagctatggcatcccc
tacattgaaacatcagccaagacccggcagggtgtggaggatgccttctacacactagta
cgtgagattcggcagcataaactgcggaaactgaacccgcctgatgagagtggccctggc
tgcatgagctgcaagtgtgtgctgtcctga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (82)   
   KEGG PATHWAY (82)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (7)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (12)   
   RefSeq(nuc) (6)   
   GenBank (3)   
   EMBL (3)   
Protein domain (13)   
   Pfam (13)   
All databases (125)   

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KEGG   Rattus norvegicus (rat): 361568
Entry
361568            CDS       T01003                                 

Gene name
Rras
Definition
(RefSeq) ras-related protein R-Ras
  KO
K07829  Ras-related protein R-Ras
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04010  MAPK signaling pathway
rno04014  Ras signaling pathway
rno04015  Rap1 signaling pathway
rno04024  cAMP signaling pathway
rno04072  Phospholipase D signaling pathway
rno04137  Mitophagy - animal
rno04140  Autophagy - animal
rno04218  Cellular senescence
rno04360  Axon guidance
rno04371  Apelin signaling pathway
rno04625  C-type lectin receptor signaling pathway
rno04810  Regulation of actin cytoskeleton
rno05132  Salmonella infection
rno05205  Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    361568 (Rras)
   04014 Ras signaling pathway
    361568 (Rras)
   04015 Rap1 signaling pathway
    361568 (Rras)
   04371 Apelin signaling pathway
    361568 (Rras)
   04072 Phospholipase D signaling pathway
    361568 (Rras)
   04024 cAMP signaling pathway
    361568 (Rras)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    361568 (Rras)
   04137 Mitophagy - animal
    361568 (Rras)
  09143 Cell growth and death
   04218 Cellular senescence
    361568 (Rras)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    361568 (Rras)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    361568 (Rras)
  09158 Development and regeneration
   04360 Axon guidance
    361568 (Rras)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    361568 (Rras)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    361568 (Rras)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04031 GTP-binding proteins [BR:rno04031]
    361568 (Rras)
GTP-binding proteins [BR:rno04031]
 Small (monomeric) G-proteins
  Ras Family
   Ras [OT]
    361568 (Rras)
SSDB
Motif
Pfam: Ras Roc Arf GTP_EFTU ATP_bind_1 MMR_HSR1 AAA_22
Other DBs
NCBI-GeneID: 361568
NCBI-ProteinID: NP_001101951
RGD: 1311443
Ensembl: ENSRNOG00000037247
UniProt: D3Z8L7
Position
1
AA seq 218 aa
MSSGAASGTGRGRPRGGGPGPRDPPPGETHKLVVVGGGGVGKSALTIQFIQSYFVSDYDP
TIEDSYTKICTVDGIPARLDILDTAGQEEFGAMREQYMRAGNGFLLVFAINDRQSFIEVS
KLFTQILRVKDRDDFPIVLVGNKADLETQRQVLRSEASSFSASHHMTYFEASAKLRLNVD
EAFEQLVRTVRKYQEQELPPSPPSAPRKKDGRCPCVLL
NT seq 657 nt   +upstreamnt  +downstreamnt
atgagcagcggggcggcgtccgggactgggcgggggcggccccggggcggggggccggga
cccagggaccccccgcccggcgagactcacaagctggtggtcgtaggcggcggcggcgtg
ggcaagagcgcgctgaccatccagttcatccagtcctactttgtgtctgactatgacccc
accattgaggattcctacacaaagatctgcacggtggacggcatccctgcacggctggac
atcctggacactgcggggcaagaggaattcggcgccatgcgggagcagtacatgcgtgct
ggcaatggcttcttgctggtgtttgccattaacgacaggcagagtttcattgaagtaagc
aagctcttcactcagatcctcagggtcaaggaccgcgatgacttccccattgtgctggtt
gggaacaaggcagatctggagacacagcgccaggtccttcgatcagaggcctcctccttt
agtgcttcccaccatatgacttactttgaggcctcagccaaactgcgtctaaatgtcgat
gaggcatttgagcagctggtgcggactgtccggaaataccaggagcaagaactccctcct
agcccacccagtgcccctaggaagaaggatgggaggtgcccctgtgtcctgctgtag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (14)   
   KEGG PATHWAY (14)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (4)   
   RefSeq(nuc) (2)   
   GenBank (1)   
   EMBL (1)   
Protein domain (7)   
   Pfam (7)   
All databases (38)   

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KEGG   Rattus norvegicus (rat): 365355
Entry
365355            CDS       T01003                                 

Gene name
Rras2
Definition
(RefSeq) ras-related protein R-Ras2
  KO
K07830  Ras-related protein R-Ras2
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04010  MAPK signaling pathway
rno04014  Ras signaling pathway
rno04024  cAMP signaling pathway
rno04072  Phospholipase D signaling pathway
rno04137  Mitophagy - animal
rno04140  Autophagy - animal
rno04218  Cellular senescence
rno04371  Apelin signaling pathway
rno04625  C-type lectin receptor signaling pathway
rno04810  Regulation of actin cytoskeleton
rno05205  Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    365355 (Rras2)
   04014 Ras signaling pathway
    365355 (Rras2)
   04371 Apelin signaling pathway
    365355 (Rras2)
   04072 Phospholipase D signaling pathway
    365355 (Rras2)
   04024 cAMP signaling pathway
    365355 (Rras2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    365355 (Rras2)
   04137 Mitophagy - animal
    365355 (Rras2)
  09143 Cell growth and death
   04218 Cellular senescence
    365355 (Rras2)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    365355 (Rras2)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    365355 (Rras2)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    365355 (Rras2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:rno04147]
    365355 (Rras2)
   04031 GTP-binding proteins [BR:rno04031]
    365355 (Rras2)
Exosome [BR:rno04147]
 Exosomal proteins
  Exosomal proteins of colorectal cancer cells
   365355 (Rras2)
  Exosomal proteins of bladder cancer cells
   365355 (Rras2)
GTP-binding proteins [BR:rno04031]
 Small (monomeric) G-proteins
  Ras Family
   Ras [OT]
    365355 (Rras2)
SSDB
Motif
Pfam: Ras Roc Arf GTP_EFTU MMR_HSR1 RsgA_GTPase ATP_bind_1 DUF2075
Other DBs
NCBI-GeneID: 365355
NCBI-ProteinID: NP_001013452
RGD: 1310793
Ensembl: ENSRNOG00000012258
UniProt: Q5BJU0
Position
1
AA seq 204 aa
MAAAGWRDGSGQEKYRLVVVGGGGVGKSALTIQFIQSYFVTDYDPTIEDSYTKQCVIDDR
AARLDILDTAGQEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEF
PMILIGNKADLDHQRQVTQEEGQQLARQLKVTYMEASAKIRMNVDQAFHELVRVIRKFQE
QECPPSPEPTRKEKDKKGCHCVIF
NT seq 615 nt   +upstreamnt  +downstreamnt
atggccgcggccggctggcgcgacggctccggccaggagaagtaccggctcgtggtggtc
ggcggtggcggcgtgggcaagtcggcgctcaccatccagttcatccagtcctactttgtg
acggactatgatccaaccatcgaagactcatacacaaaacagtgtgtgatcgatgatcga
gcggcccggctggacattttggatacagccggacaagaggagtttggagccatgagagag
cagtacatgaggacaggcgagggcttcctgttggtcttctcagttacagatagaggcagt
tttgaagaaatctataagtttcaaagacagattctcagagtaaaggatcgtgatgagttt
cccatgattttaattggcaataaagcagacctggaccatcagagacaggtaacgcaggaa
gaagggcagcagttagcgcggcagctcaaggtcacgtatatggaggcgtcggcaaagatc
aggatgaatgtagatcaagctttccacgaacttgtccgagttatcaggaagtttcaagaa
caagaatgtcctccttcaccagaaccaacccggaaagaaaaagacaagaaaggctgccat
tgtgtcattttctaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (11)   
   KEGG PATHWAY (11)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (3)   
   RefSeq(nuc) (1)   
   GenBank (1)   
   EMBL (1)   
Protein domain (8)   
   Pfam (8)   
All databases (34)   

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KEGG   Rattus norvegicus (rat): 367858
Entry
367858            CDS       T01003                                 

Definition
(RefSeq) GTPase HRas
  KO
K02833  GTPase HRas
Organism
rno  Rattus norvegicus (rat)
Pathway
rno01521  EGFR tyrosine kinase inhibitor resistance
rno01522  Endocrine resistance
rno04010  MAPK signaling pathway
rno04012  ErbB signaling pathway
rno04014  Ras signaling pathway
rno04015  Rap1 signaling pathway
rno04062  Chemokine signaling pathway
rno04068  FoxO signaling pathway
rno04071  Sphingolipid signaling pathway
rno04072  Phospholipase D signaling pathway
rno04137  Mitophagy - animal
rno04140  Autophagy - animal
rno04144  Endocytosis
rno04150  mTOR signaling pathway
rno04151  PI3K-Akt signaling pathway
rno04210  Apoptosis
rno04211  Longevity regulating pathway
rno04213  Longevity regulating pathway - multiple species
rno04218  Cellular senescence
rno04360  Axon guidance
rno04370  VEGF signaling pathway
rno04371  Apelin signaling pathway
rno04510  Focal adhesion
rno04540  Gap junction
rno04550  Signaling pathways regulating pluripotency of stem cells
rno04625  C-type lectin receptor signaling pathway
rno04630  JAK-STAT signaling pathway
rno04650  Natural killer cell mediated cytotoxicity
rno04660  T cell receptor signaling pathway
rno04662  B cell receptor signaling pathway
rno04664  Fc epsilon RI signaling pathway
rno04714  Thermogenesis
rno04720  Long-term potentiation
rno04722  Neurotrophin signaling pathway
rno04725  Cholinergic synapse
rno04726  Serotonergic synapse
rno04730  Long-term depression
rno04810  Regulation of actin cytoskeleton
rno04910  Insulin signaling pathway
rno04912  GnRH signaling pathway
rno04915  Estrogen signaling pathway
rno04916  Melanogenesis
rno04917  Prolactin signaling pathway
rno04919  Thyroid hormone signaling pathway
rno04921  Oxytocin signaling pathway
rno04926  Relaxin signaling pathway
rno04929  GnRH secretion
rno04933  AGE-RAGE signaling pathway in diabetic complications
rno04935  Growth hormone synthesis, secretion and action
rno05010  Alzheimer disease
rno05022  Pathways of neurodegeneration - multiple diseases
rno05034  Alcoholism
rno05132  Salmonella infection
rno05160  Hepatitis C
rno05161  Hepatitis B
rno05163  Human cytomegalovirus infection
rno05165  Human papillomavirus infection
rno05166  Human T-cell leukemia virus 1 infection
rno05167  Kaposi sarcoma-associated herpesvirus infection
rno05170  Human immunodeficiency virus 1 infection
rno05200  Pathways in cancer
rno05203  Viral carcinogenesis
rno05205  Proteoglycans in cancer
rno05206  MicroRNAs in cancer
rno05210  Colorectal cancer
rno05211  Renal cell carcinoma
rno05213  Endometrial cancer
rno05214  Glioma
rno05215  Prostate cancer
rno05216  Thyroid cancer
rno05218  Melanoma
rno05219  Bladder cancer
rno05220  Chronic myeloid leukemia
rno05221  Acute myeloid leukemia
rno05223  Non-small cell lung cancer
rno05224  Breast cancer
rno05225  Hepatocellular carcinoma
rno05226  Gastric cancer
rno05230  Central carbon metabolism in cancer
rno05231  Choline metabolism in cancer
rno05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
rno05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    367858
   04012 ErbB signaling pathway
    367858
   04014 Ras signaling pathway
    367858
   04015 Rap1 signaling pathway
    367858
   04370 VEGF signaling pathway
    367858
   04371 Apelin signaling pathway
    367858
   04630 JAK-STAT signaling pathway
    367858
   04068 FoxO signaling pathway
    367858
   04072 Phospholipase D signaling pathway
    367858
   04071 Sphingolipid signaling pathway
    367858
   04151 PI3K-Akt signaling pathway
    367858
   04150 mTOR signaling pathway
    367858
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    367858
   04140 Autophagy - animal
    367858
   04137 Mitophagy - animal
    367858
  09143 Cell growth and death
   04210 Apoptosis
    367858
   04218 Cellular senescence
    367858
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    367858
   04540 Gap junction
    367858
   04550 Signaling pathways regulating pluripotency of stem cells
    367858
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    367858
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    367858
   04650 Natural killer cell mediated cytotoxicity
    367858
   04660 T cell receptor signaling pathway
    367858
   04662 B cell receptor signaling pathway
    367858
   04664 Fc epsilon RI signaling pathway
    367858
   04062 Chemokine signaling pathway
    367858
  09152 Endocrine system
   04910 Insulin signaling pathway
    367858
   04929 GnRH secretion
    367858
   04912 GnRH signaling pathway
    367858
   04915 Estrogen signaling pathway
    367858
   04917 Prolactin signaling pathway
    367858
   04921 Oxytocin signaling pathway
    367858
   04926 Relaxin signaling pathway
    367858
   04935 Growth hormone synthesis, secretion and action
    367858
   04919 Thyroid hormone signaling pathway
    367858
   04916 Melanogenesis
    367858
  09156 Nervous system
   04725 Cholinergic synapse
    367858
   04726 Serotonergic synapse
    367858
   04720 Long-term potentiation
    367858
   04730 Long-term depression
    367858
   04722 Neurotrophin signaling pathway
    367858
  09158 Development and regeneration
   04360 Axon guidance
    367858
  09149 Aging
   04211 Longevity regulating pathway
    367858
   04213 Longevity regulating pathway - multiple species
    367858
  09159 Environmental adaptation
   04714 Thermogenesis
    367858
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    367858
   05206 MicroRNAs in cancer
    367858
   05205 Proteoglycans in cancer
    367858
   05203 Viral carcinogenesis
    367858
   05230 Central carbon metabolism in cancer
    367858
   05231 Choline metabolism in cancer
    367858
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    367858
  09162 Cancer: specific types
   05210 Colorectal cancer
    367858
   05225 Hepatocellular carcinoma
    367858
   05226 Gastric cancer
    367858
   05214 Glioma
    367858
   05216 Thyroid cancer
    367858
   05221 Acute myeloid leukemia
    367858
   05220 Chronic myeloid leukemia
    367858
   05218 Melanoma
    367858
   05211 Renal cell carcinoma
    367858
   05219 Bladder cancer
    367858
   05215 Prostate cancer
    367858
   05213 Endometrial cancer
    367858
   05224 Breast cancer
    367858
   05223 Non-small cell lung cancer
    367858
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    367858
   05170 Human immunodeficiency virus 1 infection
    367858
   05161 Hepatitis B
    367858
   05160 Hepatitis C
    367858
   05163 Human cytomegalovirus infection
    367858
   05167 Kaposi sarcoma-associated herpesvirus infection
    367858
   05165 Human papillomavirus infection
    367858
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    367858
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    367858
   05022 Pathways of neurodegeneration - multiple diseases
    367858
  09165 Substance dependence
   05034 Alcoholism
    367858
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    367858
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    367858
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    367858
   01522 Endocrine resistance
    367858
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:rno04131]
    367858
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:rno04147]
    367858
   04031 GTP-binding proteins [BR:rno04031]
    367858
Membrane trafficking [BR:rno04131]
 Endocytosis
  Macropinocytosis
   Ras GTPases
    367858
Exosome [BR:rno04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   367858
  Exosomal proteins of colorectal cancer cells
   367858
GTP-binding proteins [BR:rno04031]
 Small (monomeric) G-proteins
  Ras Family
   Ras [OT]
    367858
SSDB
Motif
Pfam: Ras Roc Arf RsgA_GTPase GTP_EFTU MMR_HSR1 FeoB_N G-alpha Gtr1_RagA ATP_bind_1 Septin Ldh_1_N AAA_16 PglD_N
Other DBs
NCBI-GeneID: 367858
NCBI-ProteinID: XP_017457824
RGD: 1583762
Position
X
AA seq 189 aa
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDSTIEDSYRKQVVIDGETCLMDILDTAG
QEEYSAMRDQYMRTGKGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL
AARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHKLRKLNPPDESGPG
CMSCTCVLS
NT seq 570 nt   +upstreamnt  +downstreamnt
atgacagaatacaagcttgtggtggtgggtgctggaggcgtgggaaagagtgccctgacc
atccagctgatccagaaccattttgtggacgagtatgattccactatagaggactcctac
cggaaacaggtagtcattgatggggagacgtgtttaatggacatcttagacacagcaggt
caagaagagtatagtgccatgcgggaccagtacatgcgcacagggaagggcttcctctgt
gtatttgccatcaacaacaccaagtcctttgaagacatacatcagtacagggagcagatc
aagcgggtgaaagattcagatgatgtgcctatggtgctggtgggcaacaagtgtgacctg
gccgctcgcactgttgagtctcggcaggcccaggaccttgctcgcagctatggcatcccc
tacattgaaacatcagccaagacccggcagggtgtggaggatgccttctacacactagta
cgtgagattcggcagcataaactgcggaaactgaacccgcctgatgagagtggccctggc
tgcatgagctgcacgtgtgtgctgtcctga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (82)   
   KEGG PATHWAY (82)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
   RGD (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (14)   
   Pfam (14)   
All databases (108)   

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