KEGG   Rattus norvegicus (rat): 246136
Entry
246136            CDS       T01003                                 

Gene name
Man2c1
Definition
(RefSeq) alpha-mannosidase 2C1
  KO
K01191  alpha-mannosidase [EC:3.2.1.24]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00511  Other glycan degradation
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00511 Other glycan degradation
    246136 (Man2c1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:rno04131]
    246136 (Man2c1)
Enzymes [BR:rno01000]
 3. Hydrolases
  3.2  Glycosylases
   3.2.1  Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
    3.2.1.24  alpha-mannosidase
     246136 (Man2c1)
Membrane trafficking [BR:rno04131]
 Autophagy
  Cytoplasm to vacuolar targeting (CVT) pathway
   Selective cargos
    246136 (Man2c1)
SSDB
Motif
Pfam: Glyco_hydro_38N Glyco_hydro_38C Alpha-mann_mid Glyco_hydro38C2
Other DBs
NCBI-GeneID: 246136
NCBI-ProteinID: NP_640349
RGD: 628787
Ensembl: ENSRNOG00000030654
UniProt: P21139
Position
8
AA seq 1039 aa
MAAAPFLKHWRTTFERVEKFVSPIYFTDCNLRGRLFGDSCPVTLSSFLTPERLPYEKAVQ
QNFSPAQVGDSFGPTWWTCWFRVELVIPEVWVGKEVHLCWESDGESLVWRDGEPVQGLTK
EGEKTSYVLSERLHAADPRSLTLYVEVACNGLLGAGKGSMIAAPDPEKMFQLSQAKLAVF
HRDVHNLLVDLELLLGVAKGLGEDNQRSFQALYTANQMVNICDPAQPETYPAAEALASKF
FGQRGGESQHTIHATGHCHIDTAWLWPFKETVRKCARSWSTAVKLMERNTEFTFACSQAQ
QLEWVKNQYPGLYAQLQEFACRGQFVPVGGTWVEMDGNLPSGEAMVRQFLQGQNFFLQEF
GKMCSEFWLPDTFGYSAQLPQIMQGCGIKRFLTQKLSWNLVNSFPHHTFFWEGLDGSQVL
VHFPPGDSYGMQGSVEEVLKTVTNNRDKGRTNHSGFLFGFGDGGGGPTQTMLDRLKRLGN
TDGLPRVQLSSPGQLFTALERDSGQLCTWVGELFLELHNGTYTTHAQLKKGNRECEQILH
DVELLSSLALARSAQFLYPAVQLQRLWRLLLLNQFHDVVTGSCIQLVAEDAMNYYEDIRS
HGNTLLSAAAAALCAGEPGPKGLLIINTLPWKRTEVLALPKPCGAHSLALVTVPSIGYAP
APTPTSLQPLLPQQPVFVMQETDGSVTLDNGIIRVRLDPTGCLTSLVLVASGREAIAEGA
LGNQFVLFDDVPLYWDAWDVMDYHLETRKPVRGQAGTLAVGAEGGLRGSAWFLLQISPNS
RLSQEVVLDVGCPYVRFHTEVHWHETHKFLKVEFPARVRSPQATYEIQFGHLQRPTHNNT
SWDWARYEVWAHRWIDLSECDFGLALLNNCKYGTSVRGNVLSLSLLRAPKAPDVTADMGR
HEFTYALMPHKGSFQEAGVIQAAYNLNFPLLALPAPGPAPDTTWSAFSVSSPAVVLETIK
QAEKSHQHRTLVLRLYEAHGSHVDCWLHTSLPVQEATLCDLLEQRDPTGHLSLQDNRLKL
TFSPFQVRSLLLVLQPPAN
NT seq 3120 nt   +upstreamnt  +downstreamnt
atggcggcagcgccgttcttgaagcactggcgcaccacttttgagcgggtggagaagttc
gtgtccccgatctacttcaccgactgtaaccttcgcggcaggctcttcggggacagctgc
ccggtgacactctccagcttcctgacgccggaaaggcttccctatgagaaggcagtgcag
cagaacttcagccctgcgcaggtcggcgacagcttcggacccacatggtggacctgctgg
tttcgggtagaactggtcatccctgaagtttgggtgggcaaggaagttcatctttgctgg
gaaagtgatggagaaagccttgtctggcgtgatggggaacctgtccagggtttgaccaag
gagggtgaaaagactagttatgtcctgagtgagaggctgcacgcagcagatcctcggagc
ttgactctctatgtggaagtagcctgcaatgggcttctgggagccgggaagggaagcatg
atcgcagcccctgaccctgagaagatgttccagctgagccaggctaagctggctgtgttc
caccgggatgtccacaatctcctggtggacctggagctgttgctgggtgtggccaagggc
ctcggggaggacaaccagcgcagcttccaggccctgtacacagccaaccagatggtgaac
atatgtgaccctgcgcagcctgagacttacccagcagccgaggccctggcctccaagttc
tttggccaacgtggaggtgaaagccagcataccatccatgcaacaggacactgtcacatt
gatacagcctggctttggcccttcaaggagactgtgaggaaatgtgcccggagctggtca
acagctgtgaagctcatggagcggaacactgagttcacctttgcctgctctcaggcacaa
cagctcgagtgggtaaagaaccaataccctggtctgtatgcccagctccaggagtttgcc
tgccgaggacagtttgtgcctgtggggggcacctgggtagaaatggatgggaaccttccc
agtggagaggccatggtgaggcagttcctacagggccagaacttctttctgcaagagttt
ggaaagatgtgctctgagttctggctgccagatacatttggctactcagcacagctcccc
cagatcatgcaaggctgtggcatcaaacgcttcctgacacagaaactgagctggaacttg
gtcaactccttcccacaccataccttcttctgggaggggctggatggctcccaagtgctg
gtacacttcccccctggagactcatatggaatgcagggcagtgtggaagaggtgctgaag
actgtgaccaacaaccgggacaagggacggaccaaccacagtggcttcctctttggcttc
ggggatgggggtggtggccccacacagaccatgttggaccgattgaagcggctgggcaac
actgatgggctgcccagggtgcagctgtcttctcctggacagctcttcacagcactggag
agagactcagggcagctgtgcacatgggttggggaactcttcttggagctgcacaatggc
acctatactacccatgcccagctcaagaaggggaaccgagaatgtgagcagattcttcat
gacgtggagctgctcagcagccttgccctagcccgaagtgcccagttcctgtacccggca
gtccagctgcagcgcctctggaggctcctactcctcaaccagttccatgatgtggtgact
ggaagctgcattcagctggtggcagaagatgccatgaactactatgaagacatccgttct
catggcaatacgctgctcagtgctgcagccgcagccttgtgtgctggggagccaggtccc
aagggcctcctcattatcaacacactgccctggaagcgcacagaagtgttggcactaccc
aagccttgtggggctcacagcctagccctggtgacagtgcccagtattggctatgctcct
gctcccacccctacttcactgcagcccctcctaccccagcagcccgtgtttgtgatgcag
gagactgacggttccgtgacgctggacaatggcatcatccgggtgagactggatccaact
ggctgtcttacttccctggtcctggtggcttctggcagggaagccattgctgagggtgcc
ctggggaaccagtttgtgctgtttgatgatgtgccactgtactgggatgcatgggacgtc
atggactaccatctagagacacggaagcctgtgcggggccaggcaggtaccctggcagta
ggcgctgaaggtggccttcggggtagtgcctggttcctgctacagatcagccccaacagt
cggctcagccaggaagtcgtgctggatgttggttgcccctatgtccgcttccacacggag
gtgcactggcacgagacccacaagttcctgaaggtggagttccccgctcgagtacggagc
ccccaggctacctatgagatccagtttgggcaccttcagaggccgacccacaacaacacc
tcctgggactgggctcgctatgaggtgtgggctcatcgctggatagatctgtccgagtgt
gactttgggctggccctgctcaacaactgcaagtatggaacgtcagtacgaggcaacgtc
ctcagcctctcactgctgcgtgcacccaaggctccagatgttactgctgacatggggcgc
catgaattcacttatgccttgatgccacacaagggttctttccaagaagctggtgttatc
caggctgcctacaacctcaactttcccctcttggcactgccagctccaggcccagcccct
gataccacctggagcgccttttccgtgtcttcaccagcagtcgtgttggagaccatcaag
caggccgagaagagccatcagcaccgcacactggttctaaggctgtatgaggctcatggc
agccatgtggactgctggctacacacatcattgcctgttcaggaggccaccctttgtgac
ctcctggagcagcgagaccctaccggtcacctgtcccttcaggacaaccgcctgaagctc
accttttctccctttcaagtgaggtccttattgctcgtgcttcagcctccagcaaactga

KEGG   Rattus norvegicus (rat): 361378
Entry
361378            CDS       T01003                                 

Gene name
Man2b1
Definition
(RefSeq) lysosomal alpha-mannosidase precursor
  KO
K12311  lysosomal alpha-mannosidase [EC:3.2.1.24]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00511  Other glycan degradation
rno04142  Lysosome
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00511 Other glycan degradation
    361378 (Man2b1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04142 Lysosome
    361378 (Man2b1)
Enzymes [BR:rno01000]
 3. Hydrolases
  3.2  Glycosylases
   3.2.1  Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
    3.2.1.24  alpha-mannosidase
     361378 (Man2b1)
SSDB
Motif
Pfam: Glyco_hydro_38N Glyco_hydro_38C Alpha-mann_mid Glyco_hydro38C2
Other DBs
NCBI-GeneID: 361378
NCBI-ProteinID: NP_955436
RGD: 3039
Ensembl: ENSRNOG00000023910
UniProt: Q6P762
Position
19
AA seq 1009 aa
MGTGSLAPGVRAGGGNTGWLWMSSCNLGLPVLSISFLIWLLLAAPGAQAAGYKTCPTTKP
GMLNVHLLPHTHDDVGWLKTVDQYYYGIMSDVQHASVQYILDSVIYSLLNDPTRRFIYVE
MAFFSRWWKQQTNVTQDAVRNLVRQGRLEFVNGGWVMNDEAATHYGAIVDQMTLGLRFLQ
DTFGSDGLPRVAWHIDPFGHSREQASLFAQMGFDGFFLGRIDYQDKFNRKRKLKMEELWR
ASASLKPPAADLFTGVLPNNYNPPKDLCWDVLCTDPPVVDDPTSPEFNANKLVDYFLNLA
SSQKKYYRTNHTVMTMGSDFQYENANMWFKNMDKLIRLVNEQQANGSKVHVLYSTPSCYL
WELNKANLTWTVKEDDFFPYADGPHMFWTGYFSSRPALKRYERLSYNFLQVCNQLEALVG
PEAKVGPYGSGDSAPLNEAMAVLQHHDAVTGTARQNVVNDYAKQLAAGWGPCEVLVSNAL
ARLSLYKQNFSFCREINISICPASQTSEHFRVIIYNPVGRKVDLMVRLPVSEGIFLVKDP
NDRRISSNVVMVPSAYSKTYQWELLFPASVPALGFSIYSVNKMSGHNHQAHNLTARPKKS
KSRVLVIENKYIRATFDSDTGLLRKIENLEQNISLPVRQGFFWYNASAGDEESPQASGAY
IFRPSHRKPLPVSHWAQVTLVKTNLVQEVHQNFSAWCSQVIRLYEGQRHLELEWTVGPIP
VKDDWGKEVISRFNTPMRTRGQFFTDSNGREILKRRDDFRPTWTLNQTEPVAGNYYPVNT
RIYITDGHMQLTVLTDRSQGGSSLLDGSLELMVHRRLLVDDERGVAEPLLETDTGDKVRG
RHLVILSSVSDAAARHRLLAEQEVLAPQVVLAHGGSSPYHSQAPKMQFSALRRELPPQVH
LLTLARWGPKMLLLRLEHQFAVKEDSNRNLSSPVTLNLQNLFKTFTINYLQETTLAANQP
LSRVSRLKWMTDTGPISYPAPSRLDPTSITLQPMQIRTFLASVQWQRLI
NT seq 3030 nt   +upstreamnt  +downstreamnt
atgggcaccggatcgcttgcccctggtgtccgtgctggtggcgggaacactgggtggctc
tggatgagctcctgcaacttaggtttgccagtcctgtctatttcttttcttatttggttg
ttactggctgcgcctggcgctcaggccgcgggttacaagacatgtcccaccacgaagcca
ggcatgctcaacgtgcacctgctgcctcacacacacgatgatgtgggctggctgaagaca
gtagaccaatactactacggcatcatgagtgacgtccagcatgcatctgttcagtacatc
ctagactcagtgatttactctctactgaacgatcccacccgtcgcttcatatacgtggaa
atggctttcttctcccgttggtggaagcagcagaccaatgtaacacaggacgctgtacgg
aacctggtgcgccaggggcgcctggagtttgtcaatggtggctgggtaatgaatgatgag
gcagccactcactatggtgctattgtggaccagatgacacttgggctacgcttcctgcag
gacacatttggtagtgatggacttccccgtgtggcctggcacattgacccttttggccat
tctcgagaacaggcctccctgtttgcccagatgggttttgatggcttcttcctcgggcgc
attgactaccaagataaatttaaccggaagagaaagctgaagatggaggaactctggagg
gctagcgccagcttgaagccccctgctgctgacctctttactggtgtgctccccaataat
tacaaccctccaaaagacctgtgctgggatgtgctgtgtacagaccctcccgtggtggac
gatcccacaagccctgagtttaatgccaataagttggttgattacttcctgaacctcgcc
tcttcccagaaaaagtattaccgaaccaaccacaccgtgatgaccatgggctcagacttc
cagtatgagaatgccaacatgtggttcaaaaacatggacaagcttatccgcctggtcaac
gagcagcaggcaaacgggagcaaggtccacgtgctctactccaccccttcgtgttacctc
tgggagctgaacaaggccaatctcacttggacagtgaaggaggacgacttctttccttat
gctgatggcccccacatgttctggactggctatttctccagtaggccagccctcaagcgc
tatgagcgcctcagctacaacttcctgcaggtgtgcaaccagctggaagcactggtgggt
cccgaggccaaagtgggaccctacggctcaggagacagtgcacccctcaatgaggcaatg
gcggtgctgcagcaccacgatgctgtcactggtactgcaaggcagaatgttgtcaatgac
tatgcgaagcagctggcggcaggctggggaccctgtgaggttctcgtgagcaacgctctg
gcgcgactcagcctttacaaacagaacttctcattctgtcgggagatcaacatcagtatc
tgcccagccagccagacgtcagagcacttccgggtaattatttacaaccccgtggggcgg
aaggtggatctgatggttcggctgccggtcagtgaaggcatcttccttgtgaaggaccct
aacgataggagaatttccagtaatgtggtgatggttcccagtgcttacagtaagacgtat
caatgggagctgctgttcccagcctcagtgcctgccctgggcttcagcatctactctgtg
aacaaaatgagtggccataaccatcaggcccacaacctaacggccaggcccaagaaatcc
aagtcccgtgtcttagtcattgaaaataagtacatacgggccacatttgactctgacaca
gggttattgaggaagattgaaaacctggaacagaacatttcgctccctgtgagacaaggc
ttcttttggtacaatgccagcgctggtgatgaggagagtcctcaggcctctggtgcctac
atcttcagacccagtcatcgtaaaccactgcctgtgagccactgggctcaggtcactttg
gtgaagacaaacttggtgcaggaggtacaccagaatttttcagcctggtgttcccaagtg
attcgcctgtatgaaggacagcgtcatttggagctggagtggacggtgggaccaatccca
gtgaaagatgactggggaaaggaagtcatcagccgctttaacaccccgatgagaaccagg
gggcagttcttcacggacagcaacggccgggaaatcctgaagaggagggacgatttccga
cccacctggacattaaatcagactgaaccagtggctggaaattactaccctgtcaacact
cgcatttacatcacggacgggcatatgcagctgaccgtgctgaccgaccgttcccagggg
ggcagcagtctgctggatggctcattggagctcatggttcaccgacggctgttggtagat
gatgaacgtggggtggcggaacccttgctggagacagatacgggggataaggttcgaggg
cgccaccttgtgattttgagttctgtcagtgatgcggctgcaagacaccgactgctggcg
gagcaggaagtcctggcccctcaggtggtgctggcccacgggggtagcagtccctatcac
tcgcaggcaccaaaaatgcagttctccgcacttcgccgggagctacctccgcaggtgcat
ctgctcaccctggctcgctggggtccaaagatgctgctgctgcgcttggagcaccagttc
gctgtgaaggaagattcaaatcgcaacctgagctctccggtgaccttgaacttgcagaac
ctgttcaagaccttcactatcaactacctgcaggagaccacactggcagccaaccagccc
ctatccagggtttccaggctcaagtggatgacagatactggtcccatctcctaccctgct
ccttcccggttggaccctacctcaatcacactgcagcctatgcaaatccgtaccttcctg
gcctcggttcaatggcagagactcatctag

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