KEGG   Rattus norvegicus (rat): 24715
Entry
24715             CDS       T01003                                 
Symbol
Ren
Name
(RefSeq) renin precursor
  KO
K01380  renin [EC:3.4.23.15]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04614  Renin-angiotensin system
rno04924  Renin secretion
rno05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:rno00001]
 09150 Organismal Systems
  09152 Endocrine system
   04924 Renin secretion
    24715 (Ren)
   04614 Renin-angiotensin system
    24715 (Ren)
 09160 Human Diseases
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    24715 (Ren)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:rno01002]
    24715 (Ren)
Enzymes [BR:rno01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.23  Aspartic endopeptidases
    3.4.23.15  renin
     24715 (Ren)
Peptidases and inhibitors [BR:rno01002]
 Aspartic peptidases
  Family A1: pepsin family
   24715 (Ren)
SSDB
Motif
Pfam: Asp TAXi_N TAXi_C A1_Propeptide
Other DBs
NCBI-GeneID: 24715
NCBI-ProteinID: NP_036774
RGD: 3554
Ensembl: ENSRNOG00000002937
Vega: OTTRNOG00000000631
UniProt: P08424 A6IC75
Structure
Position
13:47348312..47359539
AA seq 402 aa
MGGRRMPLWALLLLWTSCSFSLPTDTASFGRILLKKMPSVREILEERGVDMTRISAEWGE
FIKKSSFTNVTSPVVLTNYLDTQYYGEIGIGTPSQTFKVIFDTGSANLWVPSTKCGPLYT
ACEIHNLYDSSESSSYMENGTEFTIHYGSGKVKGFLSQDVVTVGGIIVTQTFGEVTELPL
IPFMLAKFDGVLGMGFPAQAVDGVIPVFDHILSQRVLKEEVFSVYYSRESHLLGGEVVLG
GSDPQHYQGNFHYVSISKAGSWQITMKGVSVGPATLLCEEGCMAVVDTGTSYISGPTSSL
QLIMQALGVKEKRANNYVVNCSQVPTLPDISFYLGGRTYTLSNMDYVQKNPFRNDDLCIL
ALQGLDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR
NT seq 1209 nt   +upstreamnt  +downstreamnt
atgggcgggaggaggatgcctctctgggcactcttgttgctctggacctcttgtagcttc
agtctcccgacagacacagccagctttggacgaatcttgctcaagaaaatgccctcggtc
cgggaaatcctggaggagcggggagtagacatgaccaggatcagtgctgaatggggtgaa
ttcatcaagaagtcttcctttaccaatgttacctcccccgtggtcctcaccaactacttg
gatacccagtactatggtgagatcggcattggtaccccatcccagaccttcaaagtcatc
tttgacacgggttcagccaacctctgggtgccctccaccaagtgtggtcccctctacact
gcctgtgagattcacaacctctatgactcctcggaatcctctagctacatggagaatggg
actgaattcaccatccactatggatcagggaaggtcaaaggtttcctcagccaagatgtg
gtaactgtgggtggaatcattgtgacacagacctttggagaggtcaccgagctgcccctg
atacccttcatgctggccaagtttgacggggttctgggcatgggcttccctgctcaggct
gttgatggagtcatccctgtcttcgaccacattctctcccagagggtgctaaaggaggaa
gtgttttctgtctactacagcagggagtcccacctgctggggggcgaagtggtgctggga
ggcagtgaccctcaacattaccagggcaactttcactacgtgagcatcagcaaggccggc
tcctggcagatcaccatgaagggggtctctgtggggcctgccaccttgttgtgtgaggag
ggctgtatggcagtggtggacactggcacatcctatatctcgggccctaccagctccctg
cagttgatcatgcaagccctgggagtcaaagagaagagagcaaataattacgttgtgaac
tgtagccaggtacccaccctccccgacatctccttctacctgggaggcaggacctacact
ctcagcaacatggactatgtgcaaaagaatcccttcaggaacgatgacctgtgcatactg
gctctccaaggcctggacatcccaccacccactgggcctgtctgggtcctgggtgccacc
ttcatccgcaagttctatacagagttcgaccggcataacaatcgcatcgggttcgccttg
gcccgctaa

  All links  
Gene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
   VEGA (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (13)   
   RefSeq(nuc) (1)   
   GenBank (6)   
   EMBL (6)   
3D Structure (1)   
   PDB (1)   
Protein domain (4)   
   Pfam (4)   
All databases (28)   

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