KEGG   Rattus norvegicus (rat): 24918Help
Entry
24918             CDS       T01003                                 

Gene name
Stat5a, Stat5
Definition
(RefSeq) signal transducer and activator of transcription 5A
  KO
K11223  signal transducer and activator of transcription 5A
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04012  ErbB signaling pathway
rno04217  Necroptosis
rno04630  Jak-STAT signaling pathway
rno04658  Th1 and Th2 cell differentiation
rno04659  Th17 cell differentiation
rno04917  Prolactin signaling pathway
rno04933  AGE-RAGE signaling pathway in diabetic complications
rno04935  Growth hormone synthesis, secretion and action
rno05161  Hepatitis B
rno05162  Measles
rno05166  Human T-cell leukemia virus 1 infection
rno05200  Pathways in cancer
rno05203  Viral carcinogenesis
rno05220  Chronic myeloid leukemia
rno05221  Acute myeloid leukemia
rno05223  Non-small cell lung cancer
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    24918 (Stat5a)
   04630 Jak-STAT signaling pathway
    24918 (Stat5a)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    24918 (Stat5a)
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    24918 (Stat5a)
   04659 Th17 cell differentiation
    24918 (Stat5a)
  09152 Endocrine system
   04917 Prolactin signaling pathway
    24918 (Stat5a)
   04935 Growth hormone synthesis, secretion and action
    24918 (Stat5a)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    24918 (Stat5a)
   05203 Viral carcinogenesis
    24918 (Stat5a)
  09162 Cancer: specific types
   05221 Acute myeloid leukemia
    24918 (Stat5a)
   05220 Chronic myeloid leukemia
    24918 (Stat5a)
   05223 Non-small cell lung cancer
    24918 (Stat5a)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    24918 (Stat5a)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    24918 (Stat5a)
   05162 Measles
    24918 (Stat5a)
   05161 Hepatitis B
    24918 (Stat5a)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:rno03000]
    24918 (Stat5a)
Transcription factors [BR:rno03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    24918 (Stat5a)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: STAT_bind STAT_alpha STAT_int SH2 Flu_B_NS1
Motif
Other DBs
NCBI-GeneID: 24918
NCBI-ProteinID: NP_058760
RGD: 3773
Ensembl: ENSRNOG00000019496
UniProt: Q62771
Position
10q31
AA seq 793 aa AA seqDB search
MAGWIQAQQLQGDALRQMQVLYGQHFPIEVRHYLAQWIESQPWDAIDLDNPQDRGQATQL
LEGLVQELQKKAEHQVGEDGFVLKIKLGHYATQLQNTYDRCPMELVRCIRHILYNEQRLV
REANNCSSPAGVLVDAMSQKHLQINQTFEELRLITQDTESELKKLQQTQEYFIIQYQESL
RIQAQFGQLAQLNPQERMSRETALQQKQVSLETWLQREAQTLQQYRVELVEKHQKTLQLL
RKQQTIILDDELIQWKRGQQLAGNGGPPEGSLDVLQSWCEKLAEIIWQNRQQIRRAEHLC
QQLPIPGPVEEMLAEVNATITDIISALVTSTFIIEKQPPQVLKTQTKFAATVRLLVGGKL
NVHMNPPQVKATIISEQQAKSLLKNENTRNDYSGEILNNCCVMEYHQATGTLSAHFRNMS
LKRIKRADRRGAESVTEEKFTVLFESQFSVGSNELVFQVKTLSLPVVVIVHGSQDHNATA
TVLWDNAFAEPGRVPFAVPDKVLWPQLCEALNMKFKAEVQSNRGLTKENLVFLAQKLFNR
RSNHLEDYNSMSVSWSQFNRENLPGWNYTFWQWFDGVMEVLKKHHKPHWNDGAILGFVNK
QQAHDLLINKPDGTFLLRFSDSEIGGITIAWKFDSPDRNLWNLKPFTTRDFSIRSLADRL
GDLNYLIYVFPDRPKDEVFAKYYTPVLAKAVDGYVKPQIKQVVPEFVNASADAGANATYM
DQAPSPVVCPQAHYNMYPPNPDPVLDQDGEFDLDETMDVARHVEELLRRPMDSLDPRLSP
PAGLFTSARSSLS
NT seq 2382 nt NT seq  +upstreamnt  +downstreamnt
atggcgggctggattcaggcccagcagctgcagggagacgctctgcgtcagatgcaagtg
ttatatgggcaacatttccccatcgaggtccggcactacctggcccagtggatcgagagc
cagccgtgggatgctattgacttggacaatccccaggaccgaggccaggccacccagctc
ctggagggcctggtgcaggagctgcagaagaaggcagaacaccaggtgggggaagatggc
tttgtgctgaagatcaagctggggcactatgccacgcagctccagaacacgtacgaccgc
tgtcccatggagctggttcgctgtatccgtcacattctgtacaatgaacagaggctggtc
cgagaagccaacaattgtagctcccctgctggtgtcctggttgacgccatgtcccagaag
caccttcagatcaaccaaacgtttgaggagctgcgcctgatcacacaggacacggagagc
gagctgaagaagctgcagcagacccaagagtacttcatcatccagtaccaggagagcctg
cggatccaagctcagtttggccagctggcccagctgaacccccaggagcgcatgagcagg
gagacagccctccagcagaagcaagtgtccctggagacctggctgcagcgagaggcacag
acactgcagcagtaccgcgtggagctggttgaaaagcaccagaagaccctgcagttgttg
aggaagcagcagaccatcatcctggacgacgagctgatccagtggaagcgggggcagcag
ctggccgggaacgggggtccccccgagggcagcctggacgtgctgcagtcctggtgtgag
aagctggccgagatcatctggcagaaccggcagcagatccgcagggctgagcacctgtgc
cagcagctgcccatccctggccccgtggaggagatgttggccgaggtcaacgccaccatc
acagacatcatctcagccctggtcaccagcacgttcatcatcgagaagcagcctcctcag
gtcctgaagacccagaccaagttcgcggccaccgtgcgcctgctggtgggcgggaagctg
aacgtgcacatgaaccctccgcaggtgaaggcgaccatcatcagcgagcagcaggccaag
tccctgctcaagaacgagaacacccgcaatgattacagtggcgagatcctgaacaactgc
tgcgtcatggagtaccaccaggccacaggcaccctcagtgcccacttcagaaacatgtca
ctgaaaagaatcaagcgtgctgacagacgcggtgccgagtctgtgacggaggagaagttc
acggtgctgtttgagtctcagttcagcgttggcagcaacgagctggtgttccaggtgaag
accctgtccctccctgtggtcgtcattgttcatggcagccaggaccacaatgctactgcc
accgtgctgtgggacaatgcctttgctgagccgggcagggtgccatttgccgtgcctgac
aaggtgctgtggccgcagctgtgtgaggcgctcaacatgaagttcaaggctgaggtgcag
agcaaccggggcttgaccaaggagaacctcgtgttcctggcacagaaactgttcaacagg
aggagcaaccacctcgaggactacaacagcatgtccgtgtcctggtcccagttcaaccgg
gagaacttgcccggctggaactataccttctggcagtggttcgacggggtgatggaggtg
ctgaagaagcatcataagccccactggaatgatggggccatcttgggtttcgtgaacaag
cagcaggcccatgacctgctcatcaacaagccagatgggacctttctgctgcgattcagc
gactcggaaatcgggggcatcaccattgcttggaagtttgactccccggaccgaaacctg
tggaatctgaagccattcaccactcgggatttctccattcggtccctggcggaccgcctg
ggggatctgaattacctcatctacgtgttcccagaccgacccaaggatgaggtctttgcc
aagtactacactcctgtacttgcaaaagcagtcgacggatacgtgaagccacagatcaag
caagtggtccctgagtttgtcaatgcttctgcagatgctggagccaacgccacctacatg
gaccaggctccttccccagtggtgtgccctcaggctcactacaacatgtacccaccgaac
cccgaccctgtccttgaccaagatggtgaatttgacctggatgagaccatggatgttgcc
aggcatgtggaggaacttttacgccggcccatggacagtcttgacccccgcctttcccca
cctgctggcctcttcacttctgccagaagctccttgtcctga

KEGG   Rattus norvegicus (rat): 25124Help
Entry
25124             CDS       T01003                                 

Gene name
Stat1, DD6G4-4
Definition
(RefSeq) signal transducer and activator of transcription 1
  KO
K11220  signal transducer and activator of transcription 1
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04062  Chemokine signaling pathway
rno04217  Necroptosis
rno04380  Osteoclast differentiation
rno04620  Toll-like receptor signaling pathway
rno04621  NOD-like receptor signaling pathway
rno04625  C-type lectin receptor signaling pathway
rno04630  Jak-STAT signaling pathway
rno04658  Th1 and Th2 cell differentiation
rno04659  Th17 cell differentiation
rno04917  Prolactin signaling pathway
rno04919  Thyroid hormone signaling pathway
rno04933  AGE-RAGE signaling pathway in diabetic complications
rno04935  Growth hormone synthesis, secretion and action
rno05140  Leishmaniasis
rno05145  Toxoplasmosis
rno05152  Tuberculosis
rno05160  Hepatitis C
rno05161  Hepatitis B
rno05162  Measles
rno05164  Influenza A
rno05165  Human papillomavirus infection
rno05167  Kaposi sarcoma-associated herpesvirus infection
rno05168  Herpes simplex virus 1 infection
rno05169  Epstein-Barr virus infection
rno05200  Pathways in cancer
rno05212  Pancreatic cancer
rno05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
rno05321  Inflammatory bowel disease (IBD)
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 Jak-STAT signaling pathway
    25124 (Stat1)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    25124 (Stat1)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    25124 (Stat1)
   04621 NOD-like receptor signaling pathway
    25124 (Stat1)
   04625 C-type lectin receptor signaling pathway
    25124 (Stat1)
   04658 Th1 and Th2 cell differentiation
    25124 (Stat1)
   04659 Th17 cell differentiation
    25124 (Stat1)
   04062 Chemokine signaling pathway
    25124 (Stat1)
  09152 Endocrine system
   04917 Prolactin signaling pathway
    25124 (Stat1)
   04935 Growth hormone synthesis, secretion and action
    25124 (Stat1)
   04919 Thyroid hormone signaling pathway
    25124 (Stat1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    25124 (Stat1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    25124 (Stat1)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    25124 (Stat1)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    25124 (Stat1)
  09163 Immune disease
   05321 Inflammatory bowel disease (IBD)
    25124 (Stat1)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    25124 (Stat1)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    25124 (Stat1)
  09172 Infectious disease: viral
   05162 Measles
    25124 (Stat1)
   05164 Influenza A
    25124 (Stat1)
   05161 Hepatitis B
    25124 (Stat1)
   05160 Hepatitis C
    25124 (Stat1)
   05168 Herpes simplex virus 1 infection
    25124 (Stat1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    25124 (Stat1)
   05169 Epstein-Barr virus infection
    25124 (Stat1)
   05165 Human papillomavirus infection
    25124 (Stat1)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    25124 (Stat1)
   05140 Leishmaniasis
    25124 (Stat1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:rno03000]
    25124 (Stat1)
Transcription factors [BR:rno03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    25124 (Stat1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: STAT_alpha STAT_int STAT_bind SH2 TRPM_tetra BLI1
Motif
Other DBs
NCBI-GeneID: 25124
NCBI-ProteinID: NP_001029336
RGD: 3771
Ensembl: ENSRNOG00000014079
UniProt: Q6P6Q7
Position
9q22
AA seq 712 aa AA seqDB search
MSQWYELQQLDSKFLEQVHQLYDDSFPMEIRQYLAQWLEKQDWEHAAYDVSFATIRFHDL
LSQLDDQYSRFSLENNFLLQHNIRKSKRNLQDNFQEDPVQMSMIIHNCLKEERKILENAQ
RFNQAQEGNIQNTVMLDKQKELDSKVRNVKDQVMCIEHEIKTLEDLQDEYDFKCKTSQNR
ESEANGVAKSDQKQEQLLLHKMFLMLDNKRKEIIHKIRELLNSIELTQNTLINDELVEWK
RRQQSACIGGPPNACLDQLQSWFTIVAESLQQVRQQLKKLEELEQKFTYEQDPITKNKQV
LSDRTFVLFQQLIQSSFVVERQPCMPTHPQRPLVLKTGVQFTVKLRLLVKLQELNYNLKV
KVSFDKDVNEKNTVKGFRKFNILGTHTKVMNMEESTNGSLAAEFRHLQLKEQKNAGNRTN
EGPLIVTEELHSLSFETQLCQPGLVIDLETTSLPVVVISNVSQLPSGWASILWYNMLVTE
PRNLSFFLNPPCAWWSQLSEVLSWQFSSVTKRGLNADQLSMLGEKLLGPNAGPDGLIPWT
RFCKENINDKNFSFWPWIDTILELIKKHLLCLWNDGCIMGFISKERERALLKDQQPGTFL
LRFSESSREGAITFTWVERSQNGGEPDFHAVEPYTKKELSAVTFPDIIRNYKVMAAENIP
ENPLKYLYPNIDKDHAFGKYYSRPKEAPEPMELDDPKRTGYIKTELISVSEV
NT seq 2139 nt NT seq  +upstreamnt  +downstreamnt
atgtcgcagtggtacgagcttcagcagctggactccaagttcctggagcaggtgcaccag
ctgtacgatgacagtttccccatggaaatcagacagtacctggcccagtggctagaaaag
caagactgggagcatgctgcctacgacgtctcgttcgccaccatccgcttccatgacctg
ctctcccagctggatgaccagtacagccgcttttctttggagaataatttcttgttgcag
cacaacataaggaaaagcaagcgtaatctccaggataacttccaagaagatcccgtacag
atgtccatgatcatccacaactgtctgaaggaggagaggaagattttggaaaacgcccag
cgatttaatcaggcccaggagggaaatattcagaacaccgtgatgttagataaacagaag
gagctggacagtaaagtcagaaatgtgaaggaccaagtcatgtgcatagagcatgaaatc
aagaccctagaagacttacaagatgaatatgactttaaatgcaaaacctctcagaacaga
gaaagcgaagccaatggtgtggcgaagagcgaccagaaacaggaacagctgctgctgcat
aagatgttcttaatgcttgacaacaagagaaaggagataattcacaaaatcagagagctg
ctgaactccatcgagctcactcagaacactctgattaatgatgagcttgtggagtggaag
cgaagacagcagagtgcctgcattgggggaccgcccaatgcctgcctggatcagctgcaa
agctggttcaccattgttgcagagagcctgcagcaggtccgtcagcagcttaaaaagctg
gaggagttggaacagaaattcacctatgagcaggaccctattacaaaaaacaagcaggtg
ttatccgatcgcaccttcgtcctcttccagcagctcattcagagctcctttgtggtggaa
cgacagccgtgcatgccaactcaccctcagaggcccctggtcttgaagactggggtacag
ttcactgtgaagctgagactgttggtgaaattgcaagaactgaactataacttgaaagtg
aaagtctcatttgacaaagatgtgaacgagaaaaacacagtgaaaggattccggaagttc
aacatcttgggtactcacacaaaagtgatgaacatggaagaatccaccaacggaagtttg
gcagctgagttccgacacctgcaactgaaggaacagaaaaatgctgggaacagaaccaat
gagggtcctctcattgtcaccgaagaacttcactctcttagctttgaaacccagttgtgc
cagccaggcttggtgattgaccttgagaccacctctcttcccgtcgtggtgatctccaat
gtcagccagctccccagtggctgggcttctatcctgtggtacaacatgctggtgacagag
cccaggaatctctccttcttcctgaaccccccgtgtgcgtggtggtcccagctctcagag
gtgctgagttggcagttttcgtcagtcaccaagagaggtctcaacgctgaccagctgagc
atgctgggggagaagcttctgggccctaatgctggccctgatggtcttattccatggaca
aggttctgtaaggaaaatattaacgataagaatttctccttctggccttggattgacacc
atcctagaactcattaagaagcacctgctttgcctctggaatgatgggtgcatcatgggc
tttatcagcaaggagcgagaacgtgctctgctcaaggaccagcagcccgggacgttcctg
cttaggttcagtgagagctcccgggaaggggccatcacattcacatgggtggaacggtcc
caaaatggaggtgaacccgacttccatgctgttgagccctacacgaagaaagaactttca
gctgttactttcccagatattattcgcaattacaaagtcatggctgctgagaatatacca
gagaatcccctgaagtatctgtatcccaatattgacaaagaccatgccttcgggaagtac
tactccaggccaaaggaagcaccagaaccgatggagctcgatgaccctaagagaactgga
tacatcaagactgagttgatttctgtgtctgaagtgtaa

KEGG   Rattus norvegicus (rat): 25125Help
Entry
25125             CDS       T01003                                 

Gene name
Stat3
Definition
(RefSeq) signal transducer and activator of transcription 3
  KO
K04692  signal transducer and activator of transcription 3
Organism
rno  Rattus norvegicus (rat)
Pathway
rno01521  EGFR tyrosine kinase inhibitor resistance
rno04062  Chemokine signaling pathway
rno04066  HIF-1 signaling pathway
rno04068  FoxO signaling pathway
rno04217  Necroptosis
rno04550  Signaling pathways regulating pluripotency of stem cells
rno04630  Jak-STAT signaling pathway
rno04659  Th17 cell differentiation
rno04917  Prolactin signaling pathway
rno04920  Adipocytokine signaling pathway
rno04931  Insulin resistance
rno04933  AGE-RAGE signaling pathway in diabetic complications
rno04935  Growth hormone synthesis, secretion and action
rno05145  Toxoplasmosis
rno05160  Hepatitis C
rno05161  Hepatitis B
rno05162  Measles
rno05163  Human cytomegalovirus infection
rno05167  Kaposi sarcoma-associated herpesvirus infection
rno05169  Epstein-Barr virus infection
rno05200  Pathways in cancer
rno05203  Viral carcinogenesis
rno05205  Proteoglycans in cancer
rno05206  MicroRNAs in cancer
rno05212  Pancreatic cancer
rno05221  Acute myeloid leukemia
rno05223  Non-small cell lung cancer
rno05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
rno05321  Inflammatory bowel disease (IBD)
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 Jak-STAT signaling pathway
    25125 (Stat3)
   04066 HIF-1 signaling pathway
    25125 (Stat3)
   04068 FoxO signaling pathway
    25125 (Stat3)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    25125 (Stat3)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    25125 (Stat3)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    25125 (Stat3)
   04062 Chemokine signaling pathway
    25125 (Stat3)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    25125 (Stat3)
   04917 Prolactin signaling pathway
    25125 (Stat3)
   04935 Growth hormone synthesis, secretion and action
    25125 (Stat3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    25125 (Stat3)
   05206 MicroRNAs in cancer
    25125 (Stat3)
   05205 Proteoglycans in cancer
    25125 (Stat3)
   05203 Viral carcinogenesis
    25125 (Stat3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    25125 (Stat3)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    25125 (Stat3)
   05221 Acute myeloid leukemia
    25125 (Stat3)
   05223 Non-small cell lung cancer
    25125 (Stat3)
  09163 Immune disease
   05321 Inflammatory bowel disease (IBD)
    25125 (Stat3)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    25125 (Stat3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    25125 (Stat3)
  09172 Infectious disease: viral
   05162 Measles
    25125 (Stat3)
   05161 Hepatitis B
    25125 (Stat3)
   05160 Hepatitis C
    25125 (Stat3)
   05163 Human cytomegalovirus infection
    25125 (Stat3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    25125 (Stat3)
   05169 Epstein-Barr virus infection
    25125 (Stat3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    25125 (Stat3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    25125 (Stat3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:rno03000]
    25125 (Stat3)
Transcription factors [BR:rno03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    25125 (Stat3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: STAT_alpha STAT_bind STAT_int SH2 E2R135 Syntaxin-6_N Fib_alpha
Motif
Other DBs
NCBI-GeneID: 25125
NCBI-ProteinID: NP_036879
RGD: 3772
Ensembl: ENSRNOG00000019742
UniProt: P52631
Position
10q31
AA seq 770 aa AA seqDB search
MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNL
LGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAA
TAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLK
SQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEEL
ADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQ
HRPMLEERIVDLFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNY
QLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGN
GGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWY
NMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYS
GCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILST
KPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIM
DATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGSAAPYLKTKFICVTPTTCSN
TIDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFESLTFDMDLTSECATSPM
NT seq 2313 nt NT seq  +upstreamnt  +downstreamnt
atggctcagtggaaccagctccagcagctggacacgcgctacctggagcagcttcatcag
ctgtacagcgatagcttccccatggagctgcggcagttcctggcgccttggattgagagc
caagattgggcatatgcagccagcaaagagtcacacgccactctggtgtttcataacctc
ttgggcgagatcgaccagcagtatagccgattcctgcaggagtccaatgtcctctatcag
cacaacctgcgaagaatcaagcagttcctgcagagcaggtatcttgagaagccaatggaa
attgcccggattgtggcccgatgcctgtgggaagagtctcgcctcctccagacggcagcc
acggcagcccagcaagggggccaggccaaccaccccacagctgccgtagtgacggagaag
cagcagatgctggaacagcatcttcaggatgtccggaagcgtgtgcaggatctagaacag
aaaatgaaagtggtggagaatctccaggatgactttgatttcaactataaaaccctcaag
agtcaaggagacatgcaggatctgaatggaaacaaccagtctgtgaccagacagaagatg
cagcagctggagcagatgctcacggccctggaccagatgcggaggagcatcgtgagcgag
ctggcagggctcttgtcagcaatggagtacgtgcagaagacactgaccgatgaagagctg
gctgactggaagaggcggcagcagatagcgtgcatcggaggccctcccaacatctgcctg
gaccgtctggaaaactggataacttcattagcagaatctcaacttcagacccgccaacaa
attaagaaactggaggagctgcagcagaaagtgtcctacaagggggaccctattgtgcag
caccggccaatgctggaggagaggatcgtggatctgttcagaaacttaatgaagagtgcc
ttcgtggtggagcggcagccctgtatgcccatgcacccggaccggcccttagtcatcaag
actggtgtccagtttaccacaaaagtcaggttgctggtcaaatttcctgagttgaattat
cagcttaaaattaaagtgtgcattgataaggactctggggatgttgctgccctcagaggg
tctcggaaatttaacattctgggcacgaacacaaaggtgatgaacatggaggagtccaac
aacggcagcctgtctgcagagttcaagcacctgaccctgagggagcagagatgtgggaat
gggggccgtgccaattgtgatgcctccttgattgtcactgaggagctgcacctgatcacc
tttgagacagaggtgtaccaccaaggtctcaagatcgacctagagacccactccttgcca
gtcgtggtgatctccaacatctgtcagatgcctaatgcttgggcatcaatcctgtggtat
aacatgctgaccaataaccccaagaacgtgaacttcttcactaagcctccgattggaacc
tgggaccaagtggccgaggtgctgagctggcagttctcgtccaccaccaagcgagggctg
agcatcgagcagctgaccacgctggccgagaagctcttagggcctggtgtgaactactca
gggtgtcagatcacatgggctaagttttgcaaagaaaacatggccggcaagggcttctcg
ttctgggtctggctagacaatatcatcgaccttgtgaaaaagtatatcttggccctttgg
aatgaagggtacatcatgggtttcatcagcaaggagcgggagagggccatcctaagcaca
aagcccccgggcaccttcctgctgcggttcagtgagagcagcaaggaaggaggggtcact
ttcacttgggtggaaaaggacatcagtggcaagacccagatccagtctgtagaaccatat
accaagcagcagctgaacaacatgtcatttgctgaaatcatcatgggctataagatcatg
gacgctaccaacatcctggtatccccactggtctacctctaccctgacattcccaaggag
gaggcattcggaaagtattgtcgccccgagagccaggagcaccctgaagctgacccaggt
agtgctgccccttacctgaagaccaagttcatctgtgtgacaccaacgacctgcagcaat
accattgacctgccgatgtccccccgcactttagattcattgatgcagtttggaaataac
ggggaaggcgctgagccctcagcaggagggcagtttgagtcgctcacgtttgacatggat
ctgacctcggagtgtgctacctccccgatgtga

KEGG   Rattus norvegicus (rat): 25126Help
Entry
25126             CDS       T01003                                 

Gene name
Stat5b
Definition
(RefSeq) signal transducer and activator of transcription 5B
  KO
K11224  signal transducer and activator of transcription 5B
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04012  ErbB signaling pathway
rno04062  Chemokine signaling pathway
rno04217  Necroptosis
rno04630  Jak-STAT signaling pathway
rno04658  Th1 and Th2 cell differentiation
rno04659  Th17 cell differentiation
rno04917  Prolactin signaling pathway
rno04933  AGE-RAGE signaling pathway in diabetic complications
rno04935  Growth hormone synthesis, secretion and action
rno05161  Hepatitis B
rno05162  Measles
rno05166  Human T-cell leukemia virus 1 infection
rno05200  Pathways in cancer
rno05203  Viral carcinogenesis
rno05220  Chronic myeloid leukemia
rno05221  Acute myeloid leukemia
rno05223  Non-small cell lung cancer
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    25126 (Stat5b)
   04630 Jak-STAT signaling pathway
    25126 (Stat5b)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    25126 (Stat5b)
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    25126 (Stat5b)
   04659 Th17 cell differentiation
    25126 (Stat5b)
   04062 Chemokine signaling pathway
    25126 (Stat5b)
  09152 Endocrine system
   04917 Prolactin signaling pathway
    25126 (Stat5b)
   04935 Growth hormone synthesis, secretion and action
    25126 (Stat5b)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    25126 (Stat5b)
   05203 Viral carcinogenesis
    25126 (Stat5b)
  09162 Cancer: specific types
   05221 Acute myeloid leukemia
    25126 (Stat5b)
   05220 Chronic myeloid leukemia
    25126 (Stat5b)
   05223 Non-small cell lung cancer
    25126 (Stat5b)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    25126 (Stat5b)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    25126 (Stat5b)
   05162 Measles
    25126 (Stat5b)
   05161 Hepatitis B
    25126 (Stat5b)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:rno03000]
    25126 (Stat5b)
Transcription factors [BR:rno03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    25126 (Stat5b)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: STAT_bind STAT_alpha STAT_int SH2
Motif
Other DBs
NCBI-GeneID: 25126
NCBI-ProteinID: NP_071775
RGD: 3774
Ensembl: ENSRNOG00000019075
UniProt: P52632 A0A0G2JSR4
Position
10q31
AA seq 786 aa AA seqDB search
MAMWIQAQQLQGDALHQMQALYGQHFPIEVRHYLSQWIESQAWDSIDLDNPQENIKATQL
LEGLVQELQKKAEHQVGEDGFLLKIKLGHYATQLQNTYDRCPMELVRCIRHILYNEQRLV
REANNGSSPAGSLADAMSQKHLQINQTFEELRLITQDTESELKKLQQTQEYFIIQYQESL
RIQAQFAQLAQLNPQERMSRETALQQKQVSLETWLQREAQTLQQYRVELAEKHQKTLQLL
RKQQTIILDDELIQWKRRQQLAGNGGPPEGSLDVLQSWCEKLAEIIWQNRQQIRRAEHLC
QQLPIPGPVEEMLAEVNATITDIISALVTSTFIIEKQPPQVLKTQTKFAATVRLLVGGKL
NVHMNPPQVKATIISEQQAKSLLKNENTRNDYSGEILNNCCVMEYHQATGTLSAHFRNMS
LKRIKRSDRRGAESVTEEKFTILFDSQFSVGGNELVFQVKTLSLPVVVIVHGSQDNNATA
TVLWDNAFAEPGRVPFAVPDKVLWPQLCEALNMKFKAEVQSNRGLTKENLVFLAQKLFNS
SSNHLEDYNSMSVSWSQFNRENLPGRNYTFWQWFDGVMEVLKKHLKPHWNDGAILGFVNK
QQAHDLLINKPDGTFLLRFSDSEIGGITIAWKFDSQERMFWNLMPFTTRDFSIRSLADRL
GDLNYLIYVFPDRPKDEVYSKYYTPVPCEPATAKAADGYVKPQIKQVVPEFVNASADAGS
GATYMDQAPSPVVCPQAHYNMYPQNPDSVLDTDGDFDLEDTMDVARRVEELLGRPMDSQW
IPHAQS
NT seq 2361 nt NT seq  +upstreamnt  +downstreamnt
atggcaatgtggatacaggctcagcagctccagggcgatgcccttcatcagatgcaggcc
ttgtacggccagcatttccccatcgaggtgcgacattatttatcccagtggatcgaaagt
caagcctgggactcaatagatcttgataatccacaggagaacattaaggccacccagctc
ctggagggcctggtgcaggagctgcagaagaaggcagaacaccaggtgggggaagatggg
tttttgctgaagatcaagctggggcactatgccacgcagctccagaacacgtatgaccgc
tgccccatggagctggttcgctgtatccggcacattctatacaatgaacagaggctggtc
cgagaagccaacaacggaagctctccggctggaagtcttgctgacgccatgtcccagaag
caccttcagatcaaccaaacgtttgaggagctgcgtctgatcacacaggacacggagagc
gagctgaagaagctgcagcagacccaagagtacttcatcatccagtaccaggagagccta
cggatccaagctcagtttgcccagctggcccaactgaacccccaggagcgcatgagcagg
gagacagccctccagcagaagcaagtgtccctggagacctggctgcagcgagaggcacag
acactgcagcagtaccgcgtggagctggctgaaaagcaccagaagaccctgcagctgctg
aggaagcagcagaccatcatcctggacgacgagctgatccagtggaagcggcgacagcaa
ctggccgggaatgggggtcctcctgagggcagcctggatgtgctgcagtcctggtgtgag
aagctggccgagatcatctggcagaaccggcagcagatccgcagggctgagcacctgtgc
cagcagctgcccatcccaggccccgtggaggagatgctggccgaggtcaacgccaccatc
acagacatcatctcagccctggtcaccagcacgttcatcatcgagaagcagcctcctcag
gtcctgaagacccagaccaagttcgcggccaccgtgcgcctgctggtgggcgggaagctg
aacgtgcacatgaaccctccgcaggtgaaggcaaccatcatcagcgagcagcaggccaag
tccctgctcaagaacgagaacacccgcaatgattatagcggcgagatcctgaacaactgc
tgcgtcatggagtaccaccaggccacaggcaccctcagcgcccacttcagaaacatgtcc
ctgaaacgaatcaagaggtctgaccgccgtggtgcagagtcggtcacggaagagaagttc
acaatcttgtttgactcacagttcagtgttggtggaaatgagctggtctttcaagtcaag
accttgtcgctcccggtggtggtgatcgttcacggcagccaggacaacaatgcgacggct
accgtcctctgggacaacgcctttgcagagcctggcagggtgccatttgccgtgcctgac
aaggtgctgtggccgcagctgtgtgaggcgctcaacatgaagttcaaggctgaggtgcag
agcaaccggggcttgaccaaggagaacctcgtgttcctggcacagaaactgttcaacagc
agcagcaaccacctcgaggactacaacagcatgtccgtgtcctggtcccagttcaaccgg
gagaatctgccaggacggaattacactttctggcagtggtttgacggtgtgatggaggtg
ttaaagaaacatctcaagcctcactggaacgatggggccatcttgggtttcgtgaacaag
cagcaggcccacgacctgctcatcaacaagccagatgggaccttcctgctgcgcttcagc
gactcggaaatcgggggcatcaccattgcttggaagtttgactcccaggagagaatgttt
tggaatctgatgccttttaccacaagagacttctctatccggtccctcgctgaccgcctg
ggggacctgaattacctcatatacgtgtttcctgatcggccaaaggatgaagtatattct
aagtactacacaccagtcccgtgtgagcccgccaccgcgaaagcagctgacggatacgtg
aagccgcagatcaagcaagtggtccccgagtttgtcaatgcttctgcagatgcagggagc
ggcgccacctacatggaccaggctccttccccagtggtgtgccctcaggctcactataac
atgtacccacagaatcccgactctgtcctcgataccgatggggatttcgatctggaagac
acgatggacgtggcacggcgtgtggaagagctcttaggccggcccatggacagtcagtgg
atccctcacgcgcagtcatga

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