KEGG   Rattus norvegicus (rat): 25104
Entry
25104             CDS       T01003                                 
Symbol
Pc
Name
(RefSeq) pyruvate carboxylase, mitochondrial precursor
  KO
K01958  pyruvate carboxylase [EC:6.4.1.1]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00020  Citrate cycle (TCA cycle)
rno00620  Pyruvate metabolism
rno01100  Metabolic pathways
rno01200  Carbon metabolism
rno01230  Biosynthesis of amino acids
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00020 Citrate cycle (TCA cycle)
    25104 (Pc)
   00620 Pyruvate metabolism
    25104 (Pc)
Enzymes [BR:rno01000]
 6. Ligases
  6.4  Forming carbon-carbon bonds
   6.4.1  Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
    6.4.1.1  pyruvate carboxylase
     25104 (Pc)
SSDB
Motif
Pfam: CPSase_L_D2 PYC_OADA Biotin_carb_N Biotin_carb_C Biotin_lipoyl HMGL-like Dala_Dala_lig_C Biotin_lipoyl_2 ATP-grasp_3 ATPgrasp_ST NQRA_N Ntox47
Other DBs
NCBI-GeneID: 25104
NCBI-ProteinID: NP_036876
RGD: 3262
Ensembl: ENSRNOG00000019372
UniProt: P52873 A6HYX8
Position
1:211228708..211327792
AA seq 1178 aa
MLKFQTVRGGLRLLGVRRSSTAPVASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELG
IRTVAVYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENGVDAVHPGYGF
LSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTNSPINSLHEA
HEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIE
KPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPATHLDPQLRSRLTSDSVKLAK
QVGYENAGTVEFLVDKHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVSEGRSLPDL
GLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISP
HYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIPFLQNVLNNQQFLAGIVDTQF
IDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKVSPSPVDPIVPVVPIGPPPAG
FRDILLREGPEGFARAVRNHQGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFNN
LFSIENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVF
KFCEVAKENGMDVFRIFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSL
EYYMGLAEELVRAGTHILCIKDMAGLLKPAACTMLVSSLRDRFPDLPLHIHTHDTSGSGV
AAMLACAQAGADVVDVAVDSMSGMTSQPSMGALVACTKGTPLDTEVPLERVFDYSEYWEG
ARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQM
LGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGIPHGGFP
EPFRSKVLKDLPRIEGRPGASLPPLNLKELEKDLIDRHGEEVTPEDVLSAAMYPDVFAQF
KDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFEL
NGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDVKVAAGAKVVKGQPLCVL
SAMKMETVVTSPMEGTIRKVHVTKDMTLEGDDLILEIE
NT seq 3537 nt   +upstreamnt  +downstreamnt
atgctgaagttccaaacagttcgagggggcctgaggctcctgggtgtccgccgatcctcc
acagcccccgttgcctccccaaatgtccggcgtctggagtacaagcccatcaagaaagta
atggtggccaacagaggtgagattgccatccgagtgtttcgtgcctgcacagagctgggt
atccgcacagtggctgtctactcggagcaggacacaggccagatgcaccggcagaaagct
gatgaagcctaccttattggccgtgggctggctcctgtgcaagcctacctgcacattcca
gacatcattaaggtggccaaggagaatggtgtagatgctgtgcaccctggctatgggttc
ctctcagagagagcagactttgcccaggcctgccaagatgctggagtccgattcattggt
ccaagcccagaggtggtccgcaagatgggagacaaggtggaagcccgggccattgccatt
gctgcaggcgttccagtggtccctggcactaattcccccatcaattccctgcatgaggca
cacgagttctctaacacctatggtttccctattatcttcaaggctgcctatggaggtggg
ggccgtggcatgagggttgtgcatagctacgaggagctggaagagaattacacccgggcc
tactctgaggccttggcagcctttgggaatggggcattgtttgtggagaaattcattgag
aagccaagacacattgaggtgcagatcctaggggaccaatatgggaacatcttgcacttg
tatgagcgggactgctccatccagcggcggcaccagaaggtggtagagattgcccctgct
acccacctggacccccaacttcggtcacgcctcaccagtgactctgtcaaacttgccaag
caggttggctatgagaatgcaggcactgtggagttcctggtggacaagcatggcaagcac
tacttcatcgaggtcaattcccgcctgcaggtggagcacacggtcactgaggagattaca
gatgtggacctggtccatgctcagatccatgtgtccgaaggccggagcctgcctgaccta
ggcctgcggcaggaaaacatccgaatcaatggttgtgccattcagtgtcgggtcaccact
gaggaccctgcacgcagcttccagccagacactggccgcattgaggttttccggagtggt
gagggcatgggcatccgcctggacaatgcctcagcattccagggagctgtcatatccccc
cactatgactccctgctcgtcaaagtcattgcccatggcaaagaccaccctacagctgcc
accaagatgagcagagccctggcggagttccgtgtccgaggtgtaaagaccaacatcccc
ttcctgcagaatgtgctcaacaaccagcagttcctagcgggcattgtggacacccagttc
atcgatgagaaccccgagctgttccagctgcggcctgcacagaaccgggcccagaagttg
ctacattaccttggacacgtcatggtcaatggccctaccactccaatccccgtcaaggtc
agtcccagccctgtggaccccattgttcctgtggtgcccataggcccacccccagctggt
ttcagagacatccttctgcgagaggggccagagggctttgccagagctgtgcggaatcac
caggggctgctgctaatggacacaaccttccgggatgcccaccagtcactacttgccact
agagtgcgcacacacgatctcaaaaagattgcaccctacgttgcccacaacttcaacaac
ctcttcagcatagagaactggggaggagccacatttgacgtggccatgcgcttcttgtat
gagtgcccctggcggcggctccaggagctccgggagctcatccccaacatcccattccag
atgctactgaggggggccaatgctgtgggctacaccaactaccctgacaacgtggtcttc
aagttctgtgaggtggccaaagagaatggcatggacgtcttccggatctttgactccctt
aactacctgccaaacatgctgctgggcatggaagcagctggcagtgctgggggtgtggtg
gaagctgccatctcctacacgggtgacgtggctgaccccagtcgcactaaatactcactg
gagtactacatgggcttagctgaagaactggtgcgagccggcactcacatcctctgcatt
aaggacatggcaggcctgctgaagcctgcagcatgcaccatgctggtcagctccctccgg
gaccggttccccgacctcccactgcacatccatacccatgacacatcagggtcaggtgtg
gcagccatgttggcctgtgcacaagctggggctgatgttgtggatgtggcagtcgactct
atgtctgggatgacctcacagcccagcatgggggccctggtggcctgtaccaaagggact
cctctggacacagaggtacccctggagcgtgtgtttgactacagtgagtattgggaaggg
gctcgggggctgtatgcagcctttgattgcacggctaccatgaagtctggcaactcagac
gtgtatgagaatgagatcccagggggccagtacaccaacctacacttccaggcccacagc
atgggacttggctccaagttcaaggaggtcaagaaggcctatgtggaggctaaccagatg
ctgggggacctcatcaaggtgacaccatcctccaagattgtgggggatctggcccagttc
atggtgcagaacgggttgagccgggcagaggcagaagctcaggcagaagagctgtccttc
ccccgctctgtggtggagttcctgcagggctacattggcattccccatgggggtttccct
gaacccttccgttctaaggtgctaaaggacctgccaagaatagaagggaggcctggagcc
tccctccctcccttgaacctgaaggagctggagaaggacctgattgataggcatggagag
gaggtgaccccagaggacgttctctctgcagccatgtaccctgatgtctttgctcagttc
aaagacttcacggctacctttggccccctggatagcctgaatactcgtctctttcttcaa
ggacccaaaattgcagaggagtttgaggttgagctggaacggggcaagaccttgcacatc
aaagccctggctgtaagcgacctgaaccgtgctggccagaggcaggtgttctttgaactc
aatgggcagcttcgatccattctggttaaagacacccaggccatgaaggagatgcacttc
catcccaaggccttgaaggatgtgaagggccaaattggggcccctatgcctgggaaggtc
atagacgtcaaggtggcagcaggagccaaggtggttaagggccagcccctctgtgtgctc
agcgccatgaagatggagactgtggtgacttcgcccatggagggcactatccgaaaggtt
cacgtgaccaaggacatgactctggaaggcgatgacctcatcctagagattgagtga

  All links  
Gene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (13)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (10)   
DNA sequence (26)   
   RefSeq(nuc) (10)   
   GenBank (8)   
   EMBL (8)   
Protein domain (12)   
   Pfam (12)   
All databases (56)   

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