KEGG   Rattus norvegicus (rat): 25149
Entry
25149             CDS       T01003                                 
Symbol
Esr2
Name
(RefSeq) estrogen receptor beta
  KO
K08551  estrogen receptor beta
Organism
rno  Rattus norvegicus (rat)
Pathway
rno01522  Endocrine resistance
rno04081  Hormone signaling
rno04915  Estrogen signaling pathway
rno04917  Prolactin signaling pathway
rno04929  GnRH secretion
rno05200  Pathways in cancer
rno05207  Chemical carcinogenesis - receptor activation
rno05224  Breast cancer
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    25149 (Esr2)
 09150 Organismal Systems
  09152 Endocrine system
   04929 GnRH secretion
    25149 (Esr2)
   04915 Estrogen signaling pathway
    25149 (Esr2)
   04917 Prolactin signaling pathway
    25149 (Esr2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    25149 (Esr2)
   05207 Chemical carcinogenesis - receptor activation
    25149 (Esr2)
  09162 Cancer: specific types
   05224 Breast cancer
    25149 (Esr2)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    25149 (Esr2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:rno03000]
    25149 (Esr2)
  09183 Protein families: signaling and cellular processes
   03310 Nuclear receptors [BR:rno03310]
    25149 (Esr2)
Transcription factors [BR:rno03000]
 Eukaryotic type
  Zinc finger
   Cys4 estrogen receptor-like
    25149 (Esr2)
Nuclear receptors [BR:rno03310]
 3. Estrogen like
  3A. Estrogen receptor
   25149 (Esr2)
SSDB
Motif
Pfam: ERbeta_N zf-C4 Hormone_recep Alveol-reg_P311
Other DBs
NCBI-GeneID: 25149
NCBI-ProteinID: NP_036886
RGD: 2582
Ensembl: ENSRNOG00000005343
Vega: OTTRNOG00000001373
UniProt: Q62986 A0A9K3Y725 Q59IV9
Structure
Position
6:complement(100589553..100645240)
AA seq 549 aa
MSICTSSHKEFSQLRPSEDMEIKNSPSSLSSPASYNCSQSILPLEHGPIYIPSSYVDNRH
EYSAMTFYSPAVMNYSVPGSTSNLDGGPVRQSTSPNVLWPTSGHLSPLATHCQSSLLYAE
PQKSPWCEARSLEHTLPVNRETLKRKLSGSSCASPVTSPNAKRDAHFCAVCSDYASGYHY
GVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRR
ERCGYRIVRRQRSSSEQVHCLSKAKRNGGHAPRVKELLLSTLSPEQLVLTLLEAEPPNVL
VSRPSMPFTEASMMMSLTKLADKELVHMIGWAKKIPGFVELSLLDQVRLLESCWMEVLMV
GLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVK
AMILLNSSMYPLASANQEAESSRKLTHLLNAVTDALVWVIAKSGISSQQQSVRLANLLML
LSHVRHISNKGMEHLLSMKCKNVVPVYDLLLEMLNAHTLRGYKSSISGSECSSTEDSKNK
ESSQNLQSQ
NT seq 1650 nt   +upstreamnt  +downstreamnt
atgtccatctgtacctcttctcacaaggagttttctcagctgcgaccctctgaagacatg
gagatcaaaaactcaccgtcgagccttagttcccctgcttcctataactgtagccagtcc
atcctacccctggagcacggccccatctacatcccttcctcctacgtagacaaccgccat
gagtattcagctatgacattctacagtcctgctgtgatgaactacagtgttcccggcagc
accagtaacctggacggtgggcctgtccgacagagcacaagcccaaatgtgctatggcca
acttctgggcacctgtctcctttagcgacccattgccaatcatcgctcctctatgcagaa
cctcaaaagagtccttggtgtgaagcaagatcactagagcacaccttacctgtaaacaga
gagacactgaagaggaagcttagtgggagcagttgtgccagccctgttactagtccaaac
gcaaagagggatgctcacttctgcgccgtctgcagcgattatgcatctgggtatcattac
ggcgtttggtcatgtgaaggatgtaaggccttttttaaaagaagcattcaaggacataat
gattatatctgtccagccacgaatcagtgtaccatagacaagaaccggcgtaaaagctgc
caggcctgccgacttcgcaagtgttatgaagtaggaatggtcaagtgtggatccaggaga
gaacggtgtgggtaccgtatagtgcggaggcagagaagttctagcgagcaggtacactgc
ctgagcaaagccaagagaaacggtgggcatgcaccccgggtgaaggagctactgctgagc
accttgagtccagagcaactggtgctcaccctcctggaagctgaaccacccaatgtgctg
gtgagccgtcccagcatgcccttcaccgaggcctccatgatgatgtccctcactaagctg
gcggacaaggaactggtgcacatgattggctgggccaagaaaatccctggctttgtggag
ctcagcctgttggaccaagtccggctcttagaaagctgctggatggaggtgctaatggtg
ggactgatgtggcgctccatcgaccaccccggcaagctcattttcgctcccgacctcgtt
ctggacagggatgaggggaagtgcgtagaagggattctggaaatctttgacatgctcctg
gcgacgacgtcaaggttccgtgagttaaaactccagcacaaggagtatctctgtgtgaag
gccatgatcctcctcaactccagtatgtaccccttggcttctgcaaaccaggaggcagaa
agtagccggaagctgacacacctactgaacgcggtgacagatgccctggtctgggtgatt
gcgaagagtggtatctcctcccagcagcagtcagtccgactggccaacctcctgatgctt
ctttctcacgtcaggcacatcagtaacaagggcatggaacatctgctcagcatgaagtgc
aaaaatgtggtcccggtgtatgacctgctgctggagatgctgaatgctcacacgcttcga
gggtacaagtcctcaatctcggggtctgagtgcagctcaacagaggacagtaagaacaaa
gagagctcccagaacctacagtctcagtga

  All links  
Gene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
   VEGA (1)   
Protein sequence (6)   
   UniProt (3)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (22)   
   RefSeq(nuc) (2)   
   GenBank (10)   
   EMBL (10)   
3D Structure (4)   
   PDB (4)   
Protein domain (4)   
   Pfam (4)   
All databases (42)   

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