KEGG   Rattus norvegicus (rat): 25255
Entry
25255             CDS       T01003                                 

Gene name
Dyrk1a
Definition
(RefSeq) dual specificity tyrosine-phosphorylation-regulated kinase 1A
  KO
K08825  dual specificity tyrosine-phosphorylation-regulated kinase 1 [EC:2.7.12.1]
Organism
rno  Rattus norvegicus (rat)
Brite
KEGG Orthology (KO) [BR:rno00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rno01001]
    25255 (Dyrk1a)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:rno04131]
    25255 (Dyrk1a)
Enzymes [BR:rno01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.1  dual-specificity kinase
     25255 (Dyrk1a)
Protein kinases [BR:rno01001]
 Serine/threonine kinases: CMGC group
  DYRK family [OT]
   25255 (Dyrk1a)
Membrane trafficking [BR:rno04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Kinases
    25255 (Dyrk1a)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Filament_head
Other DBs
NCBI-GeneID: 25255
NCBI-ProteinID: NP_036923
RGD: 2528
Ensembl: ENSRNOG00000001662
UniProt: Q63470
Position
11
AA seq 763 aa
MHTGGETSACKPSSVRLAPSFSFHAAGLQMAAQMPHSHQYSDRRQPNISDQQVSALSYSD
QIQQPLTNQVMPDIVMLQRRMPQTFRDPATAPLRKLSVDLIKTYKHINEVYYAKKKRRHQ
QGQGDDSSHKKERKVYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRV
EQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEM
LSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKR
SAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPL
FSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKLPDGTWSLKKTKDGKREYKPPGT
RKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFK
KTADEGTNTSNSVSTSPAMEQSQSSGTTSSTSSSSGGSSGTSNSGRARSDPTHQHRHSGG
HFAAAVQAMDCETHSPQVRQQFPAPLGWSGTEAPTQVTVETHPVQETTFHVAPQQNALHH
HHGNSSHHHHHHHHHHHHHGQQALGNRTRPRVYNSPTNSSSTQDSMEVGHSHHSMTSLSS
STTSSSTSSSSTGNQGNQAYQNRPVAANTLDFGQNGAMDVNLTVYSNPRQETGIAGHPTY
QFSANTGPAHYMTEGHLTMRQGADREESPMTGVCVQQSPVASS
NT seq 2292 nt   +upstreamnt  +downstreamnt
atgcatacaggaggagagacttcagcatgcaaaccttcatctgtccggctcgcaccgtca
ttctcattccatgctgctggccttcagatggctgcacagatgccccattcacatcagtac
agtgaccgtcgccagccaaacataagtgaccagcaggtttctgccttatcatattctgac
cagattcagcaacctctaactaaccaggtgatgcctgacattgtcatgttacagaggcgg
atgccccaaaccttccgtgatccagcaactgctcctctgagaaaactctctgtggacttg
atcaaaacatacaagcatattaatgaggtttactatgcaaaaaagaagcgaagacaccaa
cagggccagggggacgattctagtcataagaaggagcggaaggtttacaacgatggttac
gatgacgataactatgattacattgtaaaaaacggagaaaagtggatggaccgttatgaa
atcgactccttaataggcaaaggttcatttggacaggttgtgaaagcatatgacagagtg
gaacaagaatgggtcgccattaaaatcatcaagaacaagaaggcgtttctgaatcaagcg
cagatagaagtgcggctgcttgagctcatgaacaaacatgacactgagatgaagtactac
atagtgcatttgaaacgccactttatgtttcggaaccatctctgtctagtgtttgaaatg
ctgtcctataatctctatgatttgttgaggaacaccaacttccgaggggtctctttgaac
ctgacacgaaagtttgcacaacagatgtgcacagcattgcttttccttgcgactccagaa
cttagtatcattcactgtgacttaaagccggagaacatccttctgtgtaaccccaaacga
agtgcaatcaagattgttgactttggcagctcttgtcagttggggcagaggatataccag
tatattcagagtcgcttctatcggtctccagaggtgctactgggaatgccttatgacctt
gctatcgacatgtggtcccttggatgtatcttggttgaaatgcacactggagagcctctg
ttcagtggtgccaatgaggtggatcagatgaataaaatagtggaagtcttgggcatccca
cctgctcatattcttgaccaagcaccgaaagcaagaaagttctttgagaagttgcctgat
ggcacttggagcttaaagaagaccaaagatggaaaacgggagtacaaaccaccaggaacc
cgtaaacttcataatattcttggagtggaaacaggaggacctggcgggcggcgtgctggg
gagtcaggtcacactgtagctgactacttgaagttcaaagacctcattttaaggatgctt
gattatgaccccaaaactcggattcaaccttattatgccctgcagcacagttttttcaag
aaaacagctgatgaaggtacaaacacaagcaacagtgtgtccaccagccctgccatggag
cagtcccagtcttcaggcaccacctccagcacctcctccagctcaggtggatcctcggga
acgagcaacagtgggagagccaggtcggatccgacgcaccagcatcggcacagtggcggg
cacttcgctgctgctgtccaggccatggactgtgagacacatagtccccaggtgcgccag
cagtttccggctcctctgggctggtcaggcactgaagctcctacacaagtcactgttgaa
actcatcctgttcaagaaacaacctttcatgtagcccctcagcagaatgcattgcatcat
caccatggaaacagttcccatcatcaccaccaccaccatcaccaccaccaccaccatgga
cagcaagccttgggtaaccggaccaggccaagggtctacaattctccaacaaatagctcc
tctacccaggattctatggaggttggccacagtcaccactccatgacatccctgtcttcc
tcaacaacttcttcctcgacatcttcctcctctactggtaatcaaggcaatcaggcctat
cagaaccgcccagtggctgctaacaccttggactttggacagaatggagctatggacgtt
aatttgaccgtctactccaatccccgccaagagactggcatagctggacatccaacatac
caattttctgctaatacaggtcctgcacattacatgactgaaggacatctgacgatgagg
caaggggctgatagagaagagtctcccatgacaggagtttgtgtgcaacagagtcctgta
gctagctcgtga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (9)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (7)   
DNA sequence (11)   
   RefSeq(nuc) (7)   
   GenBank (2)   
   EMBL (2)   
Protein domain (3)   
   Pfam (3)   
All databases (35)   

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