KEGG   Rattus norvegicus (rat): 25260
Entry
25260             CDS       T01003                                 
Symbol
Gstt1
Name
(RefSeq) glutathione S-transferase theta-1
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00480  Glutathione metabolism
rno00980  Metabolism of xenobiotics by cytochrome P450
rno00982  Drug metabolism - cytochrome P450
rno00983  Drug metabolism - other enzymes
rno01100  Metabolic pathways
rno01524  Platinum drug resistance
rno05200  Pathways in cancer
rno05204  Chemical carcinogenesis - DNA adducts
rno05207  Chemical carcinogenesis - receptor activation
rno05208  Chemical carcinogenesis - reactive oxygen species
rno05225  Hepatocellular carcinoma
rno05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    25260 (Gstt1)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    25260 (Gstt1)
   00982 Drug metabolism - cytochrome P450
    25260 (Gstt1)
   00983 Drug metabolism - other enzymes
    25260 (Gstt1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    25260 (Gstt1)
   05204 Chemical carcinogenesis - DNA adducts
    25260 (Gstt1)
   05207 Chemical carcinogenesis - receptor activation
    25260 (Gstt1)
   05208 Chemical carcinogenesis - reactive oxygen species
    25260 (Gstt1)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    25260 (Gstt1)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    25260 (Gstt1)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    25260 (Gstt1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:rno02000]
    25260 (Gstt1)
Enzymes [BR:rno01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     25260 (Gstt1)
Transporters [BR:rno02000]
 Other transporters
  Pores ion channels [TC:1]
   25260 (Gstt1)
SSDB
Motif
Pfam: GST_N GST_N_3 GST_N_2 GST_C GST_C_2 GST_N_4 GST_C_3
Other DBs
NCBI-GeneID: 25260
NCBI-ProteinID: NP_445745
RGD: 2765
Ensembl: ENSRNOG00000049771
UniProt: Q01579 B6DYQ8
Position
20:12856068..12873020
AA seq 240 aa
MVLELYLDLLSQPCRAIYIFAKKNNIPFQMHTVELRKGEHLSDAFAQVNPMKKVPAMKDG
GFTLCESVAILLYLAHKYKVPDHWYPQDLQARARVDEYLAWQHTTLRRSCLRTLWHKVMF
PVFLGEQIRPEMLAATLADLDVNVQVLEDQFLQDKDFLVGPHISLADVVAITELMHPVGG
GCPVFEGRPRLAAWYRRVEAAVGKDLFLEAHEVILKVRDCPPADPVIKQKLMPRVLTMIQ
NT seq 723 nt   +upstreamnt  +downstreamnt
atggtcctggaactgtacctggatctgctgtcgcagccctgtcgcgctatttatatcttc
gccaagaagaacaatatcccgttccagatgcatactgtggagctgcgcaagggtgagcac
ctcagcgatgcctttgcccaggtgaaccccatgaagaaggtaccagccatgaaggatggt
ggcttcaccttgtgtgagagtgtggccatcctgctctacctggcgcacaagtataaggtt
cctgaccactggtacccccaagacctgcaggcccgtgctcgtgtggatgagtacctggca
tggcagcatacgacccttcggagaagctgtctccggaccctgtggcataaggtgatgttc
cccgttttcctgggtgagcagatacgcccggagatgctggcagccacattggcagatctg
gatgttaacgtacaggtgctggaagaccagttcctccaggacaaagacttccttgtcgga
ccgcacatctccctggctgacgtggtagctatcacagagctgatgcatcctgtaggtggt
ggctgcccagtctttgaagggcgtcccaggctggctgcatggtacaggagagtggaggca
gctgtggggaaggacctcttcctggaggcccatgaggtcatcctgaaggtgagagactgt
ccacctgctgaccccgtcataaagcaaaagctgatgcccagagtgctgaccatgatccag
tga

  All links  
Gene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (9)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (6)   
DNA sequence (14)   
   RefSeq(nuc) (6)   
   GenBank (4)   
   EMBL (4)   
Protein domain (7)   
   Pfam (7)   
All databases (35)   

Download RDF
DBGET integrated database retrieval system