KEGG   Rattus norvegicus (rat): 25260Help
Entry
25260             CDS       T01003                                 

Gene name
Gstt1, GSTYRS
Definition
(RefSeq) glutathione S-transferase theta 1
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00480  Glutathione metabolism
rno00980  Metabolism of xenobiotics by cytochrome P450
rno00982  Drug metabolism - cytochrome P450
rno00983  Drug metabolism - other enzymes
rno01100  Metabolic pathways
rno01524  Platinum drug resistance
rno05200  Pathways in cancer
rno05204  Chemical carcinogenesis
rno05225  Hepatocellular carcinoma
rno05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    25260 (Gstt1)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    25260 (Gstt1)
   00982 Drug metabolism - cytochrome P450
    25260 (Gstt1)
   00983 Drug metabolism - other enzymes
    25260 (Gstt1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    25260 (Gstt1)
   05204 Chemical carcinogenesis
    25260 (Gstt1)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    25260 (Gstt1)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    25260 (Gstt1)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    25260 (Gstt1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:rno02000]
    25260 (Gstt1)
Enzymes [BR:rno01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     25260 (Gstt1)
Transporters [BR:rno02000]
 Other transporters
  Pores ion channels [TC:1]
   25260 (Gstt1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: GST_N GST_N_3 GST_C GST_N_2 GST_C_2 GST_C_3 GST_N_4
Motif
Other DBs
NCBI-GeneID: 25260
NCBI-ProteinID: NP_445745
RGD: 2765
Ensembl: ENSRNOG00000049771
UniProt: Q01579 B6DYQ8
Position
20p12
AA seq 240 aa AA seqDB search
MVLELYLDLLSQPCRAIYIFAKKNNIPFQMHTVELRKGEHLSDAFAQVNPMKKVPAMKDG
GFTLCESVAILLYLAHKYKVPDHWYPQDLQARARVDEYLAWQHTTLRRSCLRTLWHKVMF
PVFLGEQIRPEMLAATLADLDVNVQVLEDQFLQDKDFLVGPHISLADVVAITELMHPVGG
GCPVFEGRPRLAAWYRRVEAAVGKDLFLEAHEVILKVRDCPPADPVIKQKLMPRVLTMIQ
NT seq 723 nt NT seq  +upstreamnt  +downstreamnt
atggtcctggaactgtacctggatctgctgtcgcagccctgtcgcgctatttatatcttc
gccaagaagaacaatatcccgttccagatgcatactgtggagctgcgcaagggtgagcac
ctcagcgatgcctttgcccaggtgaaccccatgaagaaggtaccagccatgaaggatggt
ggcttcaccttgtgtgagagtgtggccatcctgctctacctggcgcacaagtataaggtt
cctgaccactggtacccccaagacctgcaggcccgtgctcgtgtggatgagtacctggca
tggcagcatacgacccttcggagaagctgtctccggaccctgtggcataaggtgatgttc
cccgttttcctgggtgagcagatacgcccggagatgctggcagccacattggcagatctg
gatgttaacgtacaggtgctggaagaccagttcctccaggacaaagacttccttgtcgga
ccgcacatctccctggctgacgtggtagctatcacagagctgatgcatcctgtaggtggt
ggctgcccagtctttgaagggcgtcccaggctggctgcatggtacaggagagtggaggca
gctgtggggaaggacctcttcctggaggcccatgaggtcatcctgaaggtgagagactgt
ccacctgctgaccccgtcataaagcaaaagctgatgcccagagtgctgaccatgatccag
tga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (10)   
   KEGG PATHWAY (10)   
Chemical substance (45)   
   KEGG COMPOUND (45)   
Chemical reaction (23)   
   KEGG ENZYME (1)   
   KEGG REACTION (22)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (7)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (12)   
   RefSeq(nuc) (4)   
   GenBank (4)   
   EMBL (4)   
Protein domain (7)   
   Pfam (7)   
All databases (114)   

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