KEGG   Rattus norvegicus (rat): 252857
Entry
252857            CDS       T01003                                 
Symbol
Rapgef4
Name
(RefSeq) rap guanine nucleotide exchange factor 4
  KO
K04351  Rap guanine nucleotide exchange factor 4
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04015  Rap1 signaling pathway
rno04024  cAMP signaling pathway
rno04072  Phospholipase D signaling pathway
rno04261  Adrenergic signaling in cardiomyocytes
rno04670  Leukocyte transendothelial migration
rno04911  Insulin secretion
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    252857 (Rapgef4)
   04072 Phospholipase D signaling pathway
    252857 (Rapgef4)
   04024 cAMP signaling pathway
    252857 (Rapgef4)
 09150 Organismal Systems
  09151 Immune system
   04670 Leukocyte transendothelial migration
    252857 (Rapgef4)
  09152 Endocrine system
   04911 Insulin secretion
    252857 (Rapgef4)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    252857 (Rapgef4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:rno04131]
    252857 (Rapgef4)
Membrane trafficking [BR:rno04131]
 Endoplasmic reticulum (ER) - Golgi transport
  Forward pathways
   Rab associated proteins
    252857 (Rapgef4)
SSDB
Motif
Pfam: RasGEF cNMP_binding DEP RasGEF_N
Other DBs
NCBI-GeneID: 252857
NCBI-ProteinID: NP_001094112
RGD: 621886
Ensembl: ENSRNOG00000001516
Position
3:77217024..77509933
AA seq 1011 aa
MVAAHAAHSPSSAEWIACLDKRPLERSSEDVDIIFTRLKGVKAFERFHPNLLRQICLCSY
YENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSSHQDAVTICTLGIGTAFGESILDN
TPRHATIVTRENSELLRIEQEDFKALWEKYRQYMAGLLAPPYGVMETGSNNDRIPDKENT
PLIEPHVPLRPAHTITKVPSEKILRAGKILRIAILSRAPHMIRDRKYHLKTYRQCCVGTE
LVDWMIQQTSCVHSRTQAVGMWQVLLEDGVLNHVDQERHFQDKYLFYRFLDDEHEDAPLP
TEEEKKECDEELQDTMLLLSQMGPDAHMRMILRKPPGQRTADDLEIIYDELLHIKALSHL
STTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDD
FGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKV
PAGNRASNQGNSQPQQKYTVMSGTPEKILEHFLETIRLEPSLNEATDSVLNDFVMMHCVF
MPNTQLCPALVAHYHAQPSQGTEQERMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVAMA
FLEEFYVSVSDDARMMVAFKEQLAELEKTVKQISEDAKAPQKKHKVLLQQFNTGDERAQK
RQPIRGSDEVLFKVYCIDHTYTTIRVPVAASVKEVISAVADKLGSGEGLIIVKMNSGGEK
VVLKPNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTTGTVGTFELMSSKDLAYQM
TTYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKR
VQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLM
DPSRNHRAYRLTAAKLEPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTART
VRYYRSQPFNPDAAQANKNHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRRP
NT seq 3036 nt   +upstreamnt  +downstreamnt
atggttgctgcgcacgctgcacactctccgtcctcggccgagtggatcgcctgcctggat
aaaaggccgttggagcgatctagtgaagatgtggacataattttcacgcggctgaaagga
gttaaagcttttgagagatttcacccaaacctccttcgtcagatttgtttatgcagttac
tatgagaacctggagaaaggaatcacactgtttcgacaaggggacattggaaccaactgg
tatgctgtcctagctgggtctttggatgttaaagtgtctgagaccagcagtcaccaggat
gcggtgaccatctgtaccctgggaattgggacagcctttggagagtccattctcgacaac
acacctcgtcatgcaaccattgttaccagagagaacagtgagctcctccgtatcgagcag
gaagactttaaggcactatgggagaaataccgacagtatatggccggacttctggctcct
ccctatggtgttatggaaacgggctctaacaatgacaggattccggacaaggagaataca
cctctcattgaacctcacgttcctctccgccctgctcacaccattaccaaggtcccttca
gagaagatcctcagagctggaaaaattttgcgaattgccattctctctcgagcaccccac
atgataagagacagaaaataccacctaaagacatacagacaatgctgtgttgggactgag
ctggtagactggatgatacagcagacgtcctgtgttcactcccggactcaagctgttggc
atgtggcaagtcttgctggaagatggcgtcctcaaccacgtggaccaggagcgccatttc
caagataaatatttattttatcgatttctggatgacgagcatgaggatgcccctttgcct
actgaggaggagaagaaggagtgcgatgaagagctccaggacaccatgctgctgctgtca
caaatgggccctgacgcccacatgagaatgatcctgcgaaaaccacctggccagaggact
gcagatgacctagagattatctacgacgaactccttcatattaaagccttatcccatctt
tctaccacagtgaaacgggagttagcaggtgttctcatttttgagtctcacgccaaagga
ggaactgtgttgtttaaccagggggaagaaggtacctcctggtacatcattctgaaagga
tccgtgaatgtagtcatttatggcaagggtgtggtctgcaccctgcatgagggagatgac
tttggcaagttagctctggtgaacgatgctccgagagctgcatccattgttcttcgggaa
gataattgtcacttcctaagagttgacaaggaagacttcaatcggattctgagggacgtt
gaggcgaatacagtcagacttaaagaacatgaccaagatgtcttggtactggagaaggtc
ccagcagggaacagagcttctaatcaaggaaactcacagcctcagcaaaagtatactgtg
atgtcaggaacacctgaaaagattttagagcattttctagaaacaatacgccttgagcca
tctttgaatgaagcaacagattcagttttaaatgacttcgttatgatgcactgtgttttt
atgccaaacacccagctttgccccgccctcgtggcccattaccacgcacagccttctcaa
ggtacagaacaggagagaatggattacgccctcaacaacaagaggcgggtcatccgcctg
gttctgcaatgggcagccatgtatggtgatcttctccaagaagacgacgtggccatggct
ttcctggaggagttctatgtgtctgtatcagatgatgcacggatgatggtcgccttcaag
gagcagctggctgagctggagaagactgtcaaacagatctcagaagacgcaaaagctcca
cagaagaagcacaaggtgcttttgcagcagtttaatacaggtgacgagagggcccagaag
cgtcagccgattcgtggctctgatgaggttttgttcaaggtctactgcattgaccacacc
tataccaccatccgagtgcctgtagccgcctcggtgaaggaagtcatcagtgcagtagca
gacaaacttggctctggggaaggcctgatcattgtcaagatgaactctggaggagaaaag
gtggtgctcaaacctaatgatgtttcagtatttacgacgctcaccattaatggacgcctg
tttgcctgcccgcgagagcaattcgactcactgactcccttgccagaacaggagggcccg
accactgggacagtggggacgtttgaactgatgagctcgaaagacttggcgtaccagatg
acaacgtatgactgggaactcttcaactgtgtgcacgagctggagctaatctaccacaca
tttggaaggcataattttaaaaagaccacagcaaacttggatttgttcctgaggagattt
aatgaaattcagttttgggttgtcactgagatctgcctttgttcccagctcagcaaacgt
gttcagcttttgaaaaaatttatcaagatagcggctcactgcaaggagtacaaaaacctg
aattccttcttcgccatcgtcatggggctcagtaacgtggctgtgagccgcctggcatta
acatgggagaaactgccgagcaagtttaagaagttctatgcggagtttgagagcttaatg
gatccttccagaaatcacagggcgtacaggctgacagcagctaaactggagccccccctc
atccctttcatgcccttgcttattaaagatatgacatttactcatgaggggaacaagaca
ttcattgacaatctagtaaactttgaaaaaatgcgcatgattgcaaatactgccagaacg
gtgcgctactacaggagccagccattcaatccggatgctgctcaagctaataagaaccat
caggatgtccggagttatgtacggcaattaaatgtgattgacaaccagagaactttatca
cagatgtcacacagattagagcctcgcaggccatag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (6)   
   KEGG PATHWAY (6)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (8)   
   RefSeq(pep) (8)   
DNA sequence (12)   
   RefSeq(nuc) (8)   
   GenBank (2)   
   EMBL (2)   
Protein domain (4)   
   Pfam (4)   
All databases (39)   

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