KEGG   Rattus norvegicus (rat): 25296
Entry
25296             CDS       T01003                                 

Gene name
Bmp4
Definition
(RefSeq) bone morphogenetic protein 4 precursor
  KO
K04662  bone morphogenetic protein 4
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04060  Cytokine-cytokine receptor interaction
rno04350  TGF-beta signaling pathway
rno04390  Hippo signaling pathway
rno04550  Signaling pathways regulating pluripotency of stem cells
rno04919  Thyroid hormone signaling pathway
rno05200  Pathways in cancer
rno05217  Basal cell carcinoma
rno05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    25296 (Bmp4)
   04390 Hippo signaling pathway
    25296 (Bmp4)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    25296 (Bmp4)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    25296 (Bmp4)
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    25296 (Bmp4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    25296 (Bmp4)
  09162 Cancer: specific types
   05217 Basal cell carcinoma
    25296 (Bmp4)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    25296 (Bmp4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:rno04052]
    25296 (Bmp4)
   00536 Glycosaminoglycan binding proteins [BR:rno00536]
    25296 (Bmp4)
Cytokines and growth factors [BR:rno04052]
 Cytokines
  Transforming growth factors (RSTK binding)
   25296 (Bmp4)
Glycosaminoglycan binding proteins [BR:rno00536]
 Heparan sulfate / Heparin
  Morphogens
   25296 (Bmp4)
SSDB
Motif
Pfam: TGFb_propeptide TGF_beta
Other DBs
NCBI-GeneID: 25296
NCBI-ProteinID: NP_036959
RGD: 2213
Ensembl: ENSRNOG00000009694
UniProt: Q6AYU9
Position
15
AA seq 408 aa
MIPGNRMLMVVLLCQVLLGGASHASLIPETGKKKVAEIQGHAGGRRSGQSHELLRDFEAT
LLQMFGLRRRPQPSKSAVIPDYMRDLYRLQSGEEEEEEQSQGTGLEYPERPASRANTVRS
FHHEEHLENIPGTSESSAFRFFFNLSSIPENEVISSAELRLFREQVDQGPDWEQGFHRIN
IYEVMKPPAEMVPGHLITRLLDTRLVHHNVTRWETFDVSPAVLRWTREKQPNYGLAIEVT
HLHQTRTHQGQHVRISRSLPQGSGNWAQLRPLLVTFGHDGRGHTLTRRRAKRSPKHHPQR
SRKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTL
VNSVNSSIPKACCVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGCR
NT seq 1227 nt   +upstreamnt  +downstreamnt
atgattcctggtaaccgaatgctgatggtcgttttattatgccaagtcctgctaggaggc
gcgagccatgctagtttgatacctgagaccgggaagaaaaaagtcgccgagattcagggc
cacgcgggaggacgccgctcagggcagagccatgagctcctgcgggacttcgaggcgaca
cttctgcagatgtttgggctgcgccgccgtccgcagccgagcaagagcgccgtcatcccg
gattacatgagggatctttaccggctccagtctggggaggaggaggaagaagagcagagc
cagggaaccgggcttgagtaccctgagcgtcctgccagcagagccaacactgtgaggagt
ttccatcacgaagaacatctggagaacatcccagggaccagtgagagctctgcttttcgt
ttcttctttaacctcagcagcatcccagagaatgaggtgatctcctctgcagagctccgg
ctatttcgggagcaggtggaccagggccctgactgggaacagggcttccaccgtataaac
atttatgaggttatgaagcccccagcagaaatggtgcctggacacctcatcacacgacta
ctggacaccagactagtccatcacaatgtgacacggtgggaaactttcgatgtgagccct
gcagtccttcgatggacccgggaaaagcaacccaactatgggctggccattgaggtgact
cacctccaccagacacggacccaccagggccaacatgtcaggattagccgatcgttacct
caagggagtggaaattgggcccaactccggcccctcctggtcacttttggccacgatggc
cggggtcataccttgacccgccggagggccaagcgtagtcccaagcatcacccacagcgc
tccaggaagaagaataagaactgccgtcgccattcgctctacgtggacttcagtgacgtg
ggctggaatgattggatcgtggccccaccgggctaccaggccttctactgccacggggac
tgtccctttccactggcggaccacctcaactcaaccaatcatgccattgtgcagaccctg
gtcaactccgttaattctagcatccctaaggcctgctgtgtccccaccgaactgagcgcc
atttccatgttgtatctggacgagtacgacaaggtggtgttgaaaaattatcaggagatg
gtggtggaggggtgcggatgccgctga

KEGG   Rattus norvegicus (rat): 25644
Entry
25644             CDS       T01003                                 

Gene name
Bmp6
Definition
(RefSeq) bone morphogenetic protein 6 precursor
  KO
K16620  bone morphogenetic protein 6
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04060  Cytokine-cytokine receptor interaction
rno04350  TGF-beta signaling pathway
rno04390  Hippo signaling pathway
rno04913  Ovarian steroidogenesis
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    25644 (Bmp6)
   04390 Hippo signaling pathway
    25644 (Bmp6)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    25644 (Bmp6)
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    25644 (Bmp6)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:rno04052]
    25644 (Bmp6)
Cytokines and growth factors [BR:rno04052]
 Cytokines
  Transforming growth factors (RSTK binding)
   25644 (Bmp6)
SSDB
Motif
Pfam: TGFb_propeptide TGF_beta CoV_nucleocap
Other DBs
NCBI-GeneID: 25644
NCBI-ProteinID: NP_037239
RGD: 2214
Ensembl: ENSRNOG00000013717
UniProt: Q04906
Position
17
AA seq 506 aa
MPGLGRRAQWLCWWWGLLCSCGPPPLRPPLPVAAAAAGGQLLGAGGSPVRAEQPPPQSSS
SGFLYRRLKTHEKREMQKEILSVLGLPHRPRPLHGLQQPQSPVLPQQQQSQQTAREEPPP
GRLKSAPLFMLDLYNSLSKDDEEDGVSEGEGLEPESHGRASSSQLKQPSPGAAHSLNRKS
LLAPGPGGSASPLTSAQDSAFLNDADMVMSFVNLVEYDKEFSPRQRHHKEFKFNLSQIPE
GEAVTAAEFRVYKDCVVGSFKNQTFLISIYQVLQEHQHRDSDLFLLDTRVVWASEEGWLE
FDITATSNLWVVTPQHNMGLQLSVVTRDGLHINPRAAGLVGRDGPYDKQPFMVAFFKVSE
VHVRTTRSASSRRRQQSRNRSTQSQDVSRGSSASDYNSSELKTACKKHELYVSFQDLGWQ
DWIIAPKGYAANYCDGECSFPLNAHMNATNHAIVQTLVHLMNPEYVPKPCCAPTKLNAIS
VLYFDDNSNVILKKYRNMVVRACGCH
NT seq 1521 nt   +upstreamnt  +downstreamnt
atgcccgggctggggcggagggcgcagtggctgtgctggtggtgggggttactgtgcagc
tgcggccccccgccactgcggccccctctgccggtagccgcggccgccgccggggggcag
ctgctgggagccggcgggagccctgtgcgcgccgagcagccaccgccgcaatcctcctct
tcgggcttcctctatcggcggctcaagacccacgagaagcgggagatgcaaaaggagatc
ctgtcggtgttggggctgcctcacaggccgcggcccctgcacggtctccagcagcctcaa
tcccccgtgctcccgcagcagcaacaatcgcaacagacggcccgcgaggagccccctcca
gggcggctgaagtccgctccgctcttcatgctggatctctacaactccctgtccaaggac
gacgaagaggatggggtgtcagagggagagggactggagcccgagtcccacggaagggcc
agctcgtcccagctcaaacagccatctcccggggctgcacactccctgaaccgcaagagt
ctcctggccccgggacccggcggcagtgcgtccccactgaccagcgcgcaggacagcgct
ttcctcaacgacgcggacatggtcatgagctttgtgaacctggtggagtacgacaaggag
ttctccccacgccagcgacaccacaaggagttcaagttcaacttatcccagattcccgag
ggtgaggcagtgacggctgcagagttccgcgtctacaaggactgtgtggtggggagtttt
aaaaaccaaacttttcttatcagcatttaccaagtcttacaggagcatcagcacagagac
tctgacctatttttgttggacacccgggtggtgtgggcctccgaagaaggctggctggaa
ttcgacatcacagcaactagcaatctgtgggtggtgacaccgcagcacaacatgggactc
cagctgagtgtggtgactcgggacggactccacatcaacccccgtgcggcgggcctggtg
ggcagagacggcccttacgacaagcagcccttcatggtggccttcttcaaggtgagcgag
gtccacgtgcgcaccaccaggtcagcctccagtcggcgtcgacagcagagtcgcaatcgg
tccacccagtcgcaggacgtgtcccggggctccagtgcttcagactacaacagcagtgag
ttaaaaacagcttgcaagaagcatgagctttacgtgagcttccaggacctgggatggcag
gactggatcatcgcacccaaaggctacgctgccaactattgtgacggagagtgttccttc
cctctcaatgcacacatgaatgccaccaaccacgccattgtacagaccttggtccacctt
atgaatcccgagtacgtccccaaaccatgctgcgcaccaaccaaactgaatgccatctcg
gttctttacttcgacgacaactccaatgtcatcttgaaaaaatacaggaacatggttgtg
agagcttgtggatgtcattga

KEGG   Rattus norvegicus (rat): 29373
Entry
29373             CDS       T01003                                 

Gene name
Bmp2
Definition
(RefSeq) bone morphogenetic protein 2 precursor
  KO
K21283  bone morphogenetic protein 2
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04060  Cytokine-cytokine receptor interaction
rno04350  TGF-beta signaling pathway
rno04390  Hippo signaling pathway
rno05200  Pathways in cancer
rno05217  Basal cell carcinoma
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    29373 (Bmp2)
   04390 Hippo signaling pathway
    29373 (Bmp2)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    29373 (Bmp2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    29373 (Bmp2)
  09162 Cancer: specific types
   05217 Basal cell carcinoma
    29373 (Bmp2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:rno04052]
    29373 (Bmp2)
   00536 Glycosaminoglycan binding proteins [BR:rno00536]
    29373 (Bmp2)
Cytokines and growth factors [BR:rno04052]
 Cytokines
  Transforming growth factors (RSTK binding)
   29373 (Bmp2)
Glycosaminoglycan binding proteins [BR:rno00536]
 Heparan sulfate / Heparin
  Morphogens
   29373 (Bmp2)
SSDB
Motif
Pfam: TGFb_propeptide TGF_beta
Other DBs
NCBI-GeneID: 29373
NCBI-ProteinID: NP_058874
RGD: 2211
Ensembl: ENSRNOG00000021276
UniProt: P49001
Position
3
AA seq 394 aa
MVAGTRCLLVLLLPQVLLGGAAGLIPELGRKKFAGASGRPLSRPSDDVLSEFELRLLSMF
GLKQRPTPSKDVVVPPYMLDLYRRHSGQPGAPAPDHRLERAASRANTVRSFHHEEAIEEL
PEMSGKTSRRFFFNLSSVPTDEFLTSAELQIFREQMQEALGNSSFQHRINIYEIIKPATA
SSKFPVTRLLDTRLVTQNTSQWESFDVTPAVMRWTAQGHTNHGFVVEVAHLEEKPGVSKR
HVRISRSLHQDEHSWSQVRPLLVTFGHDGKGHPLHKREKRQAKHKQRKRLKSSCKRHPLY
VDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVNSKIPKACCV
PTELSAISMLYLDENEKVVLKNYQDMVVEGCGCR
NT seq 1185 nt   +upstreamnt  +downstreamnt
atggtggccgggacccgctgtcttctagtgttgctgcttccccaggtcctcctgggcggc
gcggccggcctcattccggagctgggccgcaagaagttcgccggggcatccggccgcccc
ttgtcccggccttcggacgacgtcctcagcgagtttgagttgaggctgctcagcatgttt
ggcctgaagcagagacccacccccagcaaggacgtcgtggtgcccccctatatgctcgac
ctgtaccgccggcactcgggccagccaggagcgcccgccccagaccaccggctggagagg
gcagccagccgcgccaacaccgtgcgcagcttccatcacgaagaagccatcgaggaactt
ccagaaatgagtgggaaaacgtcccgacgcttcttcttcaatttaagttctgtccctact
gatgagtttctcacatctgcggagctccagatttttcgggaacaaatgcaggaagctttg
ggaaatagtagtttccagcaccgaattaatatttatgaaattataaagcctgccacagcc
agctcaaaatttcctgtgaccagactattggacaccaggttagtgactcagaacacaagt
cagtgggagagctttgatgtcaccccggctgtgatgcgatggacagcacagggacacacc
aaccatgggtttgtggtggaagtggcccacttagaggagaagccaggtgtctccaagaga
catgtgaggattagcaggtctttgcaccaagatgaacacagctggtctcaggtaagacca
ctgctagtgacttttggccacgacggaaaaggacatccactccacaaacgagaaaagcgt
caagccaaacacaaacagcggaagcgtcttaagtccagctgcaaaaggcaccctttgtat
gtggacttcagtgatgtggggtggaatgactggatcgtggcccctccaggctatcatgcc
ttttactgccatggggaatgtccttttcccctggctgatcacctgaactccaccaaccat
gccatagtgcagactctggtaaactctgtgaattccaaaatccctaaggcatgctgtgtc
cccactgagcttagcgcaatctccatgttgtacctagatgaaaacgaaaaggttgtgcta
aaaaactatcaggacatggttgtggagggttgcgggtgtcgctag

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