KEGG   Rattus norvegicus (rat): 25579
Entry
25579             CDS       T01003                                 

Gene name
Map3k12, DLK, MUK, PK, Zpk
Definition
(RefSeq) mitogen activated protein kinase kinase kinase 12
  KO
K04423  mitogen-activated protein kinase kinase kinase 12 [EC:2.7.11.25]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04010  MAPK signaling pathway
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    25579 (Map3k12)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rno01001]
    25579 (Map3k12)
Enzymes [BR:rno01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.25  mitogen-activated protein kinase kinase kinase
     25579 (Map3k12)
Protein kinases [BR:rno01001]
 Serine/threonine kinases: TKL group
  MLK family
   25579 (Map3k12)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase Pkinase_fungal Sipho_Gp157
Other DBs
NCBI-GeneID: 25579
NCBI-ProteinID: NP_037187
RGD: 3988
Ensembl: ENSRNOG00000015134
UniProt: Q63796
Position
7q36
AA seq 888 aa
MACLHETRTPSPSFGGFVSTLSEASMRKLDPDTSDCTPEKDLTPTQCVLRDVVPLGGQGG
GGPSPSPGGEPPPEPFANSVLQLHEQDTGGPGGATGSPESRASRVRADEVRLQCQSGSGF
LEGLFGCLRPVWTMIGKAYSTEHKQQQEDLWEVPFEEILDLQWVGSGAQGAVFLGRFHGE
EVAVKKVRDLKETDIKHLRKLKHPNIITFKGVCTQAPCYCILMEFCAQGQLYEVLRAGRP
VTPSLLVDWSMGIAGGMNYLHLHKIIHRDLKSPNMLITYDDVVKISDFGTSKELSDKSTK
MSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSL
HLPVPSSCPDGFKILLRQCWNRKPRNRPSFRQILLHLDIASADVLSTPQETYFKSQAEWR
EEVKLHFEKIKSEGTCLHRLEEELVMRRREELRHALDIREHYERKLERANNLYMELNALM
LQLELKERELLRREQALERRCPGLLKSHTSRSLLHGNTMEKLIKKRNVPQKLSPHSKRPD
ILKTESLLPKLDAALSGVGLPGCPKAPPSPGRSRRGKTRHRKASAKGSCGDLPGLRAALP
PHEPGGLGSPGGLGVGPTAWDASPPALRGLHHDLLLRKMSSSSPDLLSAALGARGRGATG
GARDPGSPPPPQGDTPPSEGSAPGSTSPDSPGGAKGEPPPPVGPGEGVGLLGTGREGTTG
RGGSRAGYQHLTPAALLYRAAVTRSQKRGISSEEEEGEVDSEVELPPSQRWPQGPNMRQS
LSTFSSENPSDVEEGTASEPSPSGTPEVGSTNTDERPDERSDDMCSQGSEIPLDLPTSEV
VPERETSSLPMQHQDDQGPNPEDSDCDSTELDNSNSIDALPPPASLPP
NT seq 2667 nt   +upstreamnt  +downstreamnt
atggcctgcctccatgaaacccgaacaccctccccttcctttggaggctttgtgtctact
ctaagtgaggcctccatgcgaaagctggatccagacacttcagactgcacccctgagaag
gacctgacacctacccaatgtgtacttcgagatgttgtgcctctcggtgggcagggtgga
ggagggcccagcccctccccaggtggagagcctcctccagagccttttgccaatagtgtc
ctgcagctacatgagcaggatacaggtgggccagggggagccaccgggtcacctgagagt
cgagcatctagggttcgagctgatgaggtacgtctgcagtgccagagtggcagtggcttc
cttgaaggtctttttggctgcctgcgccctgtctggacaatgattggcaaagcctactcc
acagagcacaagcaacagcaggaagacctttgggaagtcccctttgaggaaatcctggac
ctgcagtgggtaggctcaggggctcagggtgccgttttcctgggacgctttcatggggag
gaggtagctgtgaagaaggttcgagacctcaaggagaccgacatcaagcatcttcgaaaa
ctgaagcaccccaacatcatcactttcaagggtgtttgcacacaggccccgtgctactgc
atcctcatggagttctgtgcccaaggacagctgtatgaggtgctcagggcgggccgcccc
gttaccccctccttgctggttgactggtccatgggcatcgctggaggcatgaattaccta
cacctgcacaaaatcatccacagagacctgaagtcacccaacatgctaatcacatacgac
gatgtggtgaagatctcagactttggcacttccaaggagctgagtgacaagagcaccaag
atgtcctttgcagggacagtagcctggatggctcctgaagtgatcagaaatgaacctgtg
tctgagaaggttgacatctggtcctttggggtggtgctttgggaattactgactggagag
attccctacaaagatgtagactcctcagccatcatctggggtgtgggaagcaacagtctt
cacctgcctgtaccctctagctgcccagacggctttaaaattctgcttcgccagtgctgg
aacagaaaacctcggaaccgcccatcattccgacagatcttgctgcacctggacatcgcc
tcggctgatgtgctctctacaccccaggagacttactttaaatcccaggcagagtggcgg
gaagaagtaaaactgcactttgaaaagattaagtcagaagggacctgtctgcaccgccta
gaagaggaactggtgatgcggagaagggaggagctcagacatgccctggacatcagggag
cactatgagcgcaagttggagagagctaacaacttgtacatggaactgaatgccctcatg
ttgcaactagaactcaaagagagggaattgctcaggcgagagcaagctttagaaaggagg
tgtcctggtctactgaagtcacacacgtcccgaagcctcctacatggaaacacgatggag
aagctcatcaagaaaaggaatgtgccacagaaactgtcaccccatagcaaaaggccagat
attctcaagacagagtctttgctacctaaactagatgcagccctaagtggggtggggctt
cctggttgtcctaaggcccccccttcacctgggaggagtcgtcgtggcaagacccgtcac
cgaaaggccagcgccaagggcagctgtggagacctgcctgggcttcgtgcagctttgcca
ccccatgagcctggaggactaggaagcccaggaggcctaggagtgggccctacagcttgg
gatgcctccccccctgctctccgtggactccaccatgaccttctacttcggaagatgtct
tcatcatccccagacctgttatcagcagcactgggagcccgaggccgaggggcaacaggg
ggagctcgggatcctggctcaccacctccaccccagggtgatactcctccaagtgaggga
tcagctcctggttccaccagcccagattcacctgggggagctaaaggggaaccacctcca
ccagtagggcctggagaaggtgtggggctgctgggaactggaagggaagggactacaggc
cggggaggaagccgggctgggtaccagcacttgacccccgctgcgctgctgtacagggct
gctgtgactcgtagtcagaaacgtggtatctcatctgaagaggaagaaggagaggtcgac
agtgaagtagagctacccccaagtcaaaggtggcctcagggcccgaacatgcgtcagtca
ctatctacgttcagctcagagaacccatcagatgtggaggaaggtacagctagtgagcct
tccccaagtggcacaccggaagttggcagcaccaacactgatgagcgaccagatgaacgg
tctgatgacatgtgctcacagggttcagaaatcccactggacctacctacttcagaggtg
gtccctgaacgtgaaaccagctccttgcccatgcaacaccaggatgaccagggccccaat
cctgaggactcagactgtgacagcactgaattggacaactccaacagcattgatgccttg
ccgcccccagcctcccttcctccatga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (13)   
   RefSeq(nuc) (3)   
   GenBank (5)   
   EMBL (5)   
Protein domain (4)   
   Pfam (4)   
All databases (34)   

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