KEGG   Rattus norvegicus (rat): 25590
Entry
25590             CDS       T01003                                 
Symbol
Chrna4
Name
(RefSeq) neuronal acetylcholine receptor subunit alpha-4 precursor
  KO
K04806  nicotinic acetylcholine receptor alpha-4
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04080  Neuroactive ligand-receptor interaction
rno04082  Neuroactive ligand signaling
rno04725  Cholinergic synapse
rno05033  Nicotine addiction
rno05207  Chemical carcinogenesis - receptor activation
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    25590 (Chrna4)
   04082 Neuroactive ligand signaling
    25590 (Chrna4)
 09150 Organismal Systems
  09156 Nervous system
   04725 Cholinergic synapse
    25590 (Chrna4)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    25590 (Chrna4)
  09165 Substance dependence
   05033 Nicotine addiction
    25590 (Chrna4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:rno04040]
    25590 (Chrna4)
Ion channels [BR:rno04040]
 Ligand-gated channels
  Acetylcholine (nicotinic)
   25590 (Chrna4)
SSDB
Motif
Pfam: Neur_chan_memb Neur_chan_LBD
Other DBs
NCBI-GeneID: 25590
NCBI-ProteinID: NP_077330
RGD: 2346
Ensembl: ENSRNOG00000011202
Vega: OTTRNOG00000002266
UniProt: P09483
Position
3:complement(188506802..188535558)
AA seq 630 aa
MEIGGPGAPPPLLLLPLLLLLGTGLLPASSHIETRAHAEERLLKRLFSGYNKWSRPVANI
SDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLRWDPGDYENVTSIRIPSELI
WRPDIVLYNNADGDFAVTHLTKAHLFYDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMK
FGSWTYDKAKIDLVSMHSRVDQLDFWESGEWVIVDAVGTYNTRKYECCAEIYPDITYAFI
IRRLPLFYTINLIIPCLLISCLTVLVFYLPSECGEKVTLCISVLLSLTVFLLLITEIIPS
TSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPRTHTMPAWVRRVFLDIVPRLLFM
KRPSVVKDNCRRLIESMHKMANAPRFWPEPVGEPGILSDICNQGLSPAPTFCNPTDTAVE
TQPTCRSPPLEVPDLKTSEVEKASPCPSPGSCPPPKSSSGAPMLIKARSLSVQHVPSSQE
AAEDGIRCRSRSIQYCVSQDGAASLADSKPTSSPTSLKARPSQLPVSDQASPCKCTCKEP
SPVSPVTVLKAGGTKAPPQHLPLSPALTRAVEGVQYIADHLKAEDTDFSVKEDWKYVAMV
IDRIFLWMFIIVCLLGTVGLFLPPWLAGMI
NT seq 1893 nt   +upstreamnt  +downstreamnt
atggagatcgggggccccggggcgccgccgccgctgctgctactgccgctgctgctgctc
ctagggaccggcctcttgcctgctagcagccacatagagacccgggcccatgcggaggag
cggctcctgaagagactcttctccggctacaacaagtggtctcggccagtagccaatatc
tcagatgtggtcctcgtccgctttggcttgtccattgctcagctcattgacgtggacgag
aagaaccagatgatgacaaccaacgtgtgggtgaagcaggagtggcacgactacaagctg
cgctgggaccctggtgactacgagaatgtcacctccatccgcatcccctctgaactcatc
tggaggcctgacatcgtcctctacaacaatgcggatggagactttgcagtcacccacctg
accaaggcccacctgttctatgacggaagggtgcagtggacacccccagccatctataag
agctcctgcagcatcgacgtcaccttcttcccctttgaccagcagaactgtaccatgaag
tttggatcctggacctacgacaaggccaagattgacttagtgagcatgcatagccgtgtg
gaccaactggacttctgggaaagtggggagtgggtcatcgtggatgctgtgggcacctac
aacaccaggaagtacgagtgctgtgccgagatctatcctgacatcacctatgccttcatt
atccgacggctgccgctattctacaccatcaacctcatcatcccgtgcctgctcatctcc
tgtctcaccgtgctggtcttctatctgccttcagagtgtggcgagaaggtcacactgtgc
atctcggtgctgctttctctcaccgtcttcctgctgctcatcaccgagatcatcccgtcc
acctcgctggtcatcccgctcatcggcgagtacctcctcttcaccatgatcttcgtcacc
ctctccatcgtcatcacggtcttcgtgctcaatgtgcaccaccgctcgccacgcacacac
acgatgcccgcctgggtgcgtagagtcttcctggacatcgtgcctcgcctcctcttcatg
aagcgcccctctgtggtcaaagacaactgccggagacttattgagtccatgcacaagatg
gccaacgccccccgcttctggccagagcctgtgggcgagcccggcatcttgagtgacatc
tgcaaccaaggtctgtcacctgccccaactttctgcaaccccacggacacagcagtcgag
acccagcctacgtgcaggtcacccccccttgaggtccctgacttgaagacatcagaggtt
gagaaggccagtccctgtccatcgcctggctcctgtcctccacccaagagcagcagtggg
gctccaatgctcatcaaagccaggtccctgagtgtccagcatgtgcccagctcccaagaa
gcagcagaagatggcatccgctgccggtctcggagtatccagtactgtgtttcccaagat
ggagctgcctccctggctgacagcaagcccaccagctccccgacctccctgaaggcccgt
ccatcccagcttcccgtgtcagaccaggcctctccatgcaaatgcacatgcaaggaacca
tctcctgtgtccccagtcactgtgctcaaggcgggaggcaccaaagcacctccccaacac
ctgcccctgtcaccagccctgacacgggcagtagaaggcgtccagtacattgcagaccac
ctcaaggcagaagacactgacttctcggtgaaggaggactggaaatacgtggccatggtc
attgaccgaatcttcctctggatgttcatcattgtctgccttctgggcactgtgggactc
ttcctgcctccctggctggctggtatgatctag

  All links  
Gene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
   VEGA (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (9)   
   RefSeq(nuc) (3)   
   GenBank (3)   
   EMBL (3)   
Protein domain (2)   
   Pfam (2)   
All databases (22)   

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