KEGG   Rattus norvegicus (rat): 257645
Entry
257645            CDS       T01003                                 

Gene name
Itgb5
Definition
(RefSeq) integrin beta-5 precursor
  KO
K06588  integrin beta 5
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04145  Phagosome
rno04151  PI3K-Akt signaling pathway
rno04510  Focal adhesion
rno04512  ECM-receptor interaction
rno04810  Regulation of actin cytoskeleton
rno05165  Human papillomavirus infection
rno05205  Proteoglycans in cancer
rno05410  Hypertrophic cardiomyopathy
rno05412  Arrhythmogenic right ventricular cardiomyopathy
rno05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    257645 (Itgb5)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    257645 (Itgb5)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    257645 (Itgb5)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    257645 (Itgb5)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    257645 (Itgb5)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    257645 (Itgb5)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    257645 (Itgb5)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    257645 (Itgb5)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    257645 (Itgb5)
   05414 Dilated cardiomyopathy
    257645 (Itgb5)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:rno04131]
    257645 (Itgb5)
  09183 Protein families: signaling and cellular processes
   04515 Cell adhesion molecules [BR:rno04515]
    257645 (Itgb5)
Membrane trafficking [BR:rno04131]
 Endocytosis
  Phagocytosis
   Integrins (complement receptors)
    257645 (Itgb5)
Cell adhesion molecules [BR:rno04515]
 Integrins
  Integrin beta subunits
   257645 (Itgb5)
SSDB
Motif
Pfam: Integrin_beta Integrin_b_cyt Integrin_B_tail PSI_integrin I-EGF_1 EGF_2 DUF4232 DUF4242 DUF2975
Other DBs
NCBI-GeneID: 257645
NCBI-ProteinID: NP_671480
RGD: 628869
Ensembl: ENSRNOG00000001795
Position
11
AA seq 799 aa
MPRVPATLYACLLGLCALVPRLAGLNICTSGSATSCEECLLIHPKCAWCSKEYFGNPRSI
ISRCDLKANLIRNGCGGEIESPASSTHVLRNLPLSSKGSSAMGSDVIQMTPQEIAVSLRP
GDQATFQLQVRQVEDYPVDLYYLMDLSLSMKDDLDNIRSLGTKLAEEMRKLTSNFRLGFG
SFVDKDISPFSYTAPRYQTNPCIGYKLFPNCVPSFGFRHLLPLTDRVDSFNEEVRKQRVS
RNRDAPEGGFDAVLQAAVCKEKIGWRKDALHLLVFTTDDVPHIALDGKLGGLVQPHDGQC
HLNEANEYTASDQMDYPSLALLGEKLAENNINLIFAVTKNHYMLYKNFTALIPGTTVEIL
HGDSKNIIQLIINAYSSIRAKVELSVWDQPEDLNLFFTATCQDGLSYPGQRKCEGLKIGD
TASFEVSVEARSCPGRHTTQSFTLRPVGFRDSLQVEVAYNCTCGCSAGLEPNSARCSGNG
TYVCGLCECDPSYLGTRCECQEGENQSGYQNLCREAEGKPLCSGRGECSCNQCSCFESEF
GRIYGPFCECDSFSCARNKGVLCSGHGECHCGECKCHVGYIGDNCNCSTDISTCRAKDGQ
ICSDRGRCVCGQCQCTEPGAFGETCEKCPTCPDACSSKRDCVECSLLHQGKPDNQTCHHQ
CKDEVITWVDSIVKDDQEAVLCFYKTAKDCVMMFSYTELPNGKSNLTVLREPECGSAPNA
MTILLAVVGSILLVGMALLAIWKLLVTIHDRREFAKFQSERSRARYEMASNPLYRKPIST
HTVDFAFNKFNKSYNGSVD
NT seq 2400 nt   +upstreamnt  +downstreamnt
atgccgcgggtgcccgcgaccctctacgcctgtctgctcgggctctgcgcgctcgtgccg
cgcctcgcagggctcaacatatgcaccagtggaagtgccacctcatgtgaagaatgcctg
ttaatccacccaaaatgtgcctggtgctccaaagagtactttggcaacccacggtccatc
atctctcggtgtgacctgaaggcaaacctcatccgaaatggctgtggaggtgagattgag
agtccggccagcagcacccacgtccttcggaacctgcctctcagcagcaagggttccagt
gccatgggctctgacgtcatccagatgacgccacaggagattgcagtgagcctccgtcca
ggtgaccaggctaccttccagctgcaggtacgccaggtggaggactatcccgtagacctg
tactacctgatggacctctccctctccatgaaggatgacttggacaacatccggagcctg
ggcaccaagcttgcggaggagatgaggaagctcactagtaacttccggttaggtttcggg
tcttttgttgacaaggacatctctccgttctcctacacagcaccgagataccagaccaat
ccatgtattggttacaagttattccccaactgtgtcccttccttcgggttccgccatctg
ctgcctctcacagacagagtggacagtttcaatgaggaagtgaggaagcagagggtgtcc
cggaaccgagatgcccccgaggggggctttgatgctgtcctccaggctgctgtctgcaag
gagaagatcggatggcgaaaggatgccctgcacttgctggtgttcacgacggacgacgtg
ccccacatcgcgttggatggaaaactgggtggcctggtccagccacacgatggccagtgt
cacctgaatgaagccaatgagtacactgcgtccgaccagatggactatccatcgcttgcc
ttgcttggggagaagctggcagagaacaatatcaacctcatctttgcagtgacgaagaac
cactatatgctctacaagaattttacagccctgatacctggaaccactgtggagattttg
catggagattccaaaaatattattcaactgattatcaatgcgtacagtagcatccgggct
aaagtggagctgtcggtctgggatcagccggaagaccttaatctcttcttcactgctacg
tgccaagatggcctatcctaccctggtcagaggaagtgtgagggtctgaagatcggggac
acggcgtcctttgaagtgtctgtggaggctcggagctgccctggcagacatacaacacag
tcttttaccttgaggcctgtgggcttccgggacagtctgcaggtagaagtcgcctacaac
tgcacgtgcggctgtagcgccgggctggagcccaacagtgccagatgcagtgggaatgga
acatacgtctgtgggctgtgcgagtgtgaccccagttacctgggcactaggtgcgagtgc
caggagggcgagaaccagagcgggtaccagaacctgtgccgggaggcggaaggcaaaccc
ctgtgcagcggacgtggggaatgcagctgcaaccagtgctcctgctttgagagtgagttc
gggaggatctacgggcccttctgcgagtgcgacagcttttcctgtgccaggaacaagggc
gtcctatgctcaggccatggcgagtgtcactgcggagaatgcaagtgccacgtcggttac
attggggacaattgtaactgctcaacagacatcagcacgtgcagggccaaggatgggcag
atctgcagcgaccgaggccgttgcgtctgtgggcagtgccagtgcacagagcctggagcc
tttggggagacgtgtgagaagtgcccaacctgccctgatgcttgcagctccaagagagac
tgtgtggaatgctcgctgcttcaccaggggaaacctgacaaccagacctgccaccaccag
tgcaaagatgaggtgatcacgtgggtagacagcattgtcaaagacgaccaggaagctgtg
ctttgcttctacaaaactgctaaggactgcgttatgatgttcagctacacagaactgccc
aatggaaagtctaacttgaccgtcctcagggagccagagtgcggaagtgcccccaatgcc
atgaccatcctgctggctgtggttggcagcatcctcctggttggaatggcactcctggcc
atctggaaactactcgtcaccatccacgaccgtcgagagtttgccaagttccaaagcgag
cgctccagggcccgttatgaaatggcctcaaaccccctgtacagaaagcccatctccaca
catactgtagattttgccttcaacaagttcaacaaatcctacaatggctcagtggactga

KEGG   Rattus norvegicus (rat): 296456
Entry
296456            CDS       T01003                                 

Gene name
Itgav
Definition
(RefSeq) integrin alpha-V isoform X1
  KO
K06487  integrin alpha V
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04145  Phagosome
rno04151  PI3K-Akt signaling pathway
rno04510  Focal adhesion
rno04512  ECM-receptor interaction
rno04514  Cell adhesion molecules
rno04810  Regulation of actin cytoskeleton
rno04919  Thyroid hormone signaling pathway
rno05163  Human cytomegalovirus infection
rno05165  Human papillomavirus infection
rno05200  Pathways in cancer
rno05205  Proteoglycans in cancer
rno05222  Small cell lung cancer
rno05410  Hypertrophic cardiomyopathy
rno05412  Arrhythmogenic right ventricular cardiomyopathy
rno05414  Dilated cardiomyopathy
rno05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    296456 (Itgav)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    296456 (Itgav)
   04514 Cell adhesion molecules
    296456 (Itgav)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    296456 (Itgav)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    296456 (Itgav)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    296456 (Itgav)
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    296456 (Itgav)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    296456 (Itgav)
   05205 Proteoglycans in cancer
    296456 (Itgav)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    296456 (Itgav)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    296456 (Itgav)
   05165 Human papillomavirus infection
    296456 (Itgav)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    296456 (Itgav)
   05410 Hypertrophic cardiomyopathy
    296456 (Itgav)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    296456 (Itgav)
   05414 Dilated cardiomyopathy
    296456 (Itgav)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:rno04131]
    296456 (Itgav)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:rno04147]
    296456 (Itgav)
   04515 Cell adhesion molecules [BR:rno04515]
    296456 (Itgav)
   04090 CD molecules [BR:rno04090]
    296456 (Itgav)
Membrane trafficking [BR:rno04131]
 Endocytosis
  Phagocytosis
   Integrins (complement receptors)
    296456 (Itgav)
Exosome [BR:rno04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   296456 (Itgav)
  Exosomal proteins of epithelial cells
   296456 (Itgav)
Cell adhesion molecules [BR:rno04515]
 Integrins
  Integrin alpha subunits
   296456 (Itgav)
CD molecules [BR:rno04090]
 Proteins
  296456 (Itgav)
SSDB
Motif
Pfam: Integrin_alpha2 FG-GAP FG-GAP_3 Integrin_alpha LYRIC DctQ Collectrin
Other DBs
NCBI-GeneID: 296456
NCBI-ProteinID: XP_038962373
RGD: 1310613
Ensembl: ENSRNOG00000004912
Position
3
AA seq 1043 aa
MADPGRLLLRPRPGGLLLLLLGLLLPFAGSFNLDVESPAEYAGPEGSYFGFAVDFFVPST
SSRMFLLVGAPKANTTQPGIIEGGQVLKCDCSSSRRCQPIEFDSTGNRDYAKDDPLEFKS
HQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSKNIDAD
GQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIISKYDPNVYSIKYNNQLAT
RTAQAIFDDSYLGYSVAVGDFNGDGIEDFVSGVPRAARTLGMVYIYDGKNMSSLHNFTGE
QMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTK
LNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGLVYIFNGRSTGLNSVPSQI
LQGQWAAQSMPPSFGYSMKGATDVDRNGYPDLVVGAFGVDRAVLYRARPVVTVNAGLEVY
PSILNQDNKICPLPGTALKVSCFNVRFCLKADGKGTLPRKLNFQVELLLDKLKQKGAIRR
ALFLHNRSPGHSKDMTVFRGGQTQCEELVAYLRDESEFRDKLTPITIFMEYRLDQRTAAD
ATGLQPILNQFTPANVSRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLTLTVK
AQNQGEGAYEAELIVSIPPQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAG
TQLLAGLRFSVHQQSEMDTSVKFDLKIQSSNSFDNVSPVVSYKVDLAVLAAVEIRGVSSP
DHIFLPIPNWEYKETPETEEDVGPVVQHIYELRNNGPSSFSKAILNLQWPYKYNNNTLLY
ILHYDIDGPMNCTADTEINPLRIKTPEKNDTAAEQGGRNHLITKRDLSLSEGDVHTLGCG
TAQCLQITCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNIIEFPYKN
LPIEDLFNSTLVTTNITWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVR
PPQEEQEREQLQPHENGEGNSET
NT seq 3132 nt   +upstreamnt  +downstreamnt
atggctgatcccgggcggctgctgctacgccctcgccccggtggcctcctgctcctgctg
ctcggcctcctactgcccttcgccggctccttcaacctggacgtcgaaagccccgccgag
tacgccggccccgagggaagttacttcggattcgccgtggacttcttcgtgcccagcacg
tcctccaggatgttcctcctggtgggagccccaaaagcaaacacaacccagcctgggatt
atagaaggagggcaagttctcaaatgtgactgctcatccagccgccggtgccagcccatt
gaatttgattcaacaggcaatcgagattatgccaaagatgacccactggagtttaaatcc
caccagtggtttggagcctccgtgaggtcaaagcaggataaaatcttggcctgtgctcca
ttgtaccactggaggactgagatgaagcaggagagagagccagttggaacctgctttctt
caggatggcacaaagaccgttgagtatgctccatgcaggtcaaaaaatattgatgctgat
ggacagggattttgtcaaggaggattcagcattgattttactaaagccgacagagtactt
cttggaggtcccggcagcttttattggcagggtcagctcatttcagatcaagtggcagaa
atcatatctaaatatgacccaaatgtctacagcatcaaatataataaccaactagccaca
cggactgcacaagcaatttttgatgacagttatttgggttactctgtggccgtgggagac
ttcaatggtgacggcattgaagattttgtttctggagttccaagagcagcaaggactttg
ggaatggtttatatttatgatgggaaaaacatgtcttcattacacaattttactggtgaa
cagatggctgcatattttggattttctgtagctgctactgacattaatggggatgattat
gcagatgtgtttattggagcccctctgttcatggaccgaggttctgatggaaaactccag
gaggtcggccaggtctcagtgtctctacagagagcgtcgggagacttccagactacaaag
ctgaacgggtttgaggtttttgccagatttggaagtgccatagctcctttgggagacctg
gaccaggatggcttcaatgacattgcaattgctgctccatatggtggcgaagataaaaag
ggacttgtttatatcttcaatggaagatccacaggcttgaattcggtgccatctcaaatc
ctgcaggggcagtgggccgctcagagcatgcccccaagctttggctattcaatgaaggga
gctacagatgtagatagaaatggatatccagacttagttgtcggagcttttggtgtggac
cgagctgtcttatacagagccagacctgttgtcaccgtaaatgctggccttgaagtgtac
cctagcattttaaatcaagacaataaaatctgcccattgcctgggacagctctcaaggtt
tcctgttttaatgtcaggttctgcttaaaggcggatggcaaagggacacttccgaggaaa
ctcaacttccaggtggagcttcttttggataaactcaagcagaagggagccatccggcga
gcactgtttctccataacaggtccccggggcactctaaggacatgactgttttcaggggg
ggacagacgcagtgtgaggaactggtcgcctatcttcgggatgaatctgagtttagagac
aagctcactcccatcactatttttatggagtatcggctggaccagagaacggctgctgat
gccacaggcttgcagcccatcctgaaccagttcactccggccaacgtcagtcggcaggct
cacattttacttgactgtggcgaagacaatgtctgtaaacctaaactggaagtttctgta
gatagtgatcaaaagaagatctatattggggatgacaaccctctgaccctgaccgtgaag
gcgcagaatcaaggagaaggcgcctatgaagctgagctcatcgtttctatcccaccacag
gctgacttcatcggggttgtccggaacaacgaagccttagcaagactgtcctgtgcattt
aagacagaaaaccaaacccggcaggtggtgtgtgaccttgggaacccgatgaaggctgga
actcaactgcttgctggccttcgtttcagcgtgcaccagcaatcagagatggatacttct
gtgaagtttgacttgaaaatccaaagctctaattcttttgacaatgtcagcccagtcgtg
tcttacaaggtcgaccttgccgttttggctgccgttgagataagaggagtttcaagccca
gatcacatctttcttccaattccaaactgggagtacaaggaaacccctgagactgaagaa
gacgttgggcctgttgttcagcacatctatgagctgagaaacaatggtccaagttcattc
agcaaggcaatcctgaacctccagtggccttacaaatacaacaacaatactttgctgtac
attctccattacgacattgatgggccgatgaactgtactgccgacacagagatcaaccct
ctgagaattaagacgcccgaaaagaatgacacagcagctgagcaaggaggaagaaatcat
ctcatcaccaagcgggatctcagcctcagtgagggagatgttcacactttgggctgtgga
actgctcagtgcttgcagatcacctgccaggtcggtcgactggatagagggaagagcgcc
atcctgtacgtgaaatccctgctgtggaccgagacgtttatgaacaaggagaaccagaac
cattcctattccctgaagtcatccgcttcatttaatatcatagaattcccttacaagaat
cttccgattgaggatctcttcaactctacgctagtcaccacgaacatcacctggggcatt
cagccagcacccatgcctgtgcctgtgtgggtgatcatcttggcggttctcgcagggctg
ctgttactggccgtgttggtatttgtaatgtacaggatgggctttttcaaacgtgtccga
ccacctcaagaagagcaagaaagagaacagcttcagcctcatgagaacggcgaaggaaac
tctgaaacctaa

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