KEGG   Rattus norvegicus (rat): 26202
Entry
26202             CDS       T01003                                 

Gene name
ND5
Definition
(RefSeq) NADH dehydrogenase subunit 5
  KO
K03883  NADH-ubiquinone oxidoreductase chain 5 [EC:7.1.1.2]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00190  Oxidative phosphorylation
rno01100  Metabolic pathways
rno04714  Thermogenesis
rno04723  Retrograde endocannabinoid signaling
rno05010  Alzheimer disease
rno05012  Parkinson disease
rno05014  Amyotrophic lateral sclerosis
rno05016  Huntington disease
rno05020  Prion disease
rno05022  Pathways of neurodegeneration - multiple diseases
Module
rno_M00142  NADH:ubiquinone oxidoreductase, mitochondria
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    26202 (ND5)
 09150 Organismal Systems
  09156 Nervous system
   04723 Retrograde endocannabinoid signaling
    26202 (ND5)
  09159 Environmental adaptation
   04714 Thermogenesis
    26202 (ND5)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    26202 (ND5)
   05012 Parkinson disease
    26202 (ND5)
   05014 Amyotrophic lateral sclerosis
    26202 (ND5)
   05016 Huntington disease
    26202 (ND5)
   05020 Prion disease
    26202 (ND5)
   05022 Pathways of neurodegeneration - multiple diseases
    26202 (ND5)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03029 Mitochondrial biogenesis [BR:rno03029]
    26202 (ND5)
Enzymes [BR:rno01000]
 7. Translocases
  7.1  Catalysing the translocation of hydrons
   7.1.1  Linked to oxidoreductase reactions
    7.1.1.2  NADH:ubiquinone reductase (H+-translocating)
     26202 (ND5)
Mitochondrial biogenesis [BR:rno03029]
 Mitochondrial DNA transcription, translation, and replication factors
  Mitochondrial DNA-encoded proteins
   Mitochondrial respiratory chain complex I
    26202 (ND5)
SSDB
Motif
Pfam: Proton_antipo_M NADH5_C Proton_antipo_N DUF3930
Other DBs
NCBI-GeneID: 26202
NCBI-ProteinID: YP_665639
RGD: 620560
UniProt: P11661 Q8SEZ0
Position
MT
AA seq 609 aa
MNMMTSSILMILILLTTPIIISMTNLPKLIDFPSYATSSIKFSFLLSLLPLLLFFHHNTE
YMITNWHWLTINSIKLTMSFKIDYFSILFLSVALFVTWSIMQFSSWYMHSDPHINRFIKY
LMMFLITMLILTSANNLFQLFIGWEGVGIMSFLLIGWWYGRADANTAALQAILYNRVGDI
GFILAMTWFCLNMNSWELQQIFLTNTNNLVPLTGLLIAATGKSAQFGLHPWLPSAMEGPT
PVSALLHSSTMVVAGIFLMIRFHPLTSNNSTIMTAMLCLGAITTLFTAICALTQNDIKKI
VAFSTSSQLGLMMVTLGINQPYLAFLHICTHAFFKAMLFMCSGSIIHSLNDEQDIRKMGN
MMKAMPFTSSCLIIGSLALTGMPFLTGFYSKDLIIEAINTCNTNAWALMITLIATSMTAV
YSMRIIYFVTMTKPRYSPLITINENNPNLINPIKRLALGSILAGFLISLNIPPTNIQILT
MPWHLKMTALLITILGFAIALELNNLTLNLSMSKPTKLSSFSTSLGYYPPIMHRIIPQKT
LNSSYKLSLNLLDLIWLEKTIPKSTSITQTQLSKMMSNQKGLIKLYFLSFLITISLIFIL
HTLNPEWFQ
NT seq 1830 nt   +upstreamnt  +downstreamnt
ataaatataataacatcctcaatcctcataatcttgattttacttacaacaccaatcatc
atttccataaccaacctaccaaaacttattgactttccgtcatatgctacttcatcaatt
aaattctcattcctccttagcctcttacctttactactattcttccaccacaacacagaa
tatataattactaactgacattgactaactattaattctattaaacttactataagtttc
aaaattgactatttctcaatcctattcctatcagtagccctattcgtaacatgatcaatc
atacaattctcttcatgatatatacactctgatccccacattaaccgattcattaagtac
ttaataatattcctaattactatactaattctaacctcagctaacaatctattccaactc
tttattggatgagaaggagtaggaattatatccttcttattaatcggatgatgatatggc
cgtgcagacgccaacacagcggccctccaagcaatcctctacaaccgagtcggagacatt
ggtttcatcctagctataacctgattctgcctaaacataaactcctgagaactccaacaa
attttcttaaccaataccaacaatctagtccctctcacaggactactaattgcagccaca
ggaaaatccgcccaattcggacttcatccatgactcccatcagctatagaaggcccaact
cccgtctctgccctactacactcaagcacaatagttgtggcagggatcttcctaataatc
cgattccaccccctaacctcaaacaatagtactattataacagccatactatgtcttggt
gcaatcaccacattattcacagcaatctgtgctctcacccaaaacgacatcaaaaaaatt
gtagctttctcaacatccagccaactaggccttataatagtcacattagggattaaccaa
ccctaccttgctttcctccacatttgcacccatgcattcttcaaagccatattattcata
tgctccggatcaatcatccatagcctcaacgatgaacaagacattcgaaaaataggcaat
ataataaaagcaataccattcacatcatcttgtctcattatcgggagcctagcccttacc
ggaatacctttcctcacaggattctattcaaaagatctcatcatcgaagccatcaacacg
tgtaacaccaacgcctgagccctaataatcactttaatcgccacatccataactgctgtg
tacagtatacgcatcatctacttcgtcaccatgacaaaaccacgatactccccactaatt
actattaatgaaaacaacccaaacctcattaatccaatcaaacgcctagcattaggaagc
atcctagcaggcttccttatctcactaaatattcctccaactaacattcaaattctcaca
ataccctgacatttaaaaataacagccctactcattacaatcctaggatttgccattgcc
ctagaacttaacaatttaacactaaatctatcaataagcaaacccaccaaactatcatca
ttctcaacctccctaggctactacccaccaattatacaccgaattattcctcaaaaaact
ctaaattctagctacaaattatccttaaacctactagacctaatctgactagaaaagaca
atcccaaaatcaacctcaatcacccaaacccaactatctaaaataatatccaaccaaaaa
gggctaatcaaactatatttcctatcatttctcatcactatttcactaatttttatctta
cacacacttaatcccgagtgatttcaataa

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