KEGG   Rattus norvegicus (rat): 266802
Entry
266802            CDS       T01003                                 
Symbol
Alk
Name
(RefSeq) ALK tyrosine kinase receptor precursor
  KO
K05119  anaplastic lymphoma kinase [EC:2.7.10.1]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno05200  Pathways in cancer
rno05223  Non-small cell lung cancer
rno05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:rno00001]
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    266802 (Alk)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    266802 (Alk)
  09162 Cancer: specific types
   05223 Non-small cell lung cancer
    266802 (Alk)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rno01001]
    266802 (Alk)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:rno04090]
    266802 (Alk)
Enzymes [BR:rno01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     266802 (Alk)
Protein kinases [BR:rno01001]
 Receptor tyrosine kinases (RTK)
  ALK family
   266802 (Alk)
CD molecules [BR:rno04090]
 Proteins
  266802 (Alk)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase MAM Gly_rich FXa_inhibition Nup96
Other DBs
NCBI-GeneID: 266802
NCBI-ProteinID: NP_001162572
RGD: 628622
Ensembl: ENSRNOG00000008683
UniProt: F1LRZ0
Position
6:28631431..29351321
AA seq 1617 aa
MGALGFLWLLPPLLLTAASYSGAATDQRAGSPASGPPLQPREPLSYSRLQRKSLAVDFVV
PSLFRVYARDLLLPQPPSPSEPGAGGLEARGSLALDCDPLLRLLGPSPGISWAEGASSPS
PEAAPTLSRVLKGGSVRKLRRAKQLVLELGEETILEGCIGPPEEAAAVGILQFNLSELFS
WWILHGEGRLRIRLMPEKKASEVGREGRLSTAIRASQPRLLFQIFGTGHSSLESPSEMPS
PPGNFLWNLTWTMKDSFPFLSHRSRYGLECSFDFPCELEYSPPLHTHGNQSWSWRRVPSE
EASRMNLLDGPEAEHLKEMPRGSFLLLNTSADSKHTILSPWMRSSSEHCTLAVSVHRHLQ
PSGRYVAQLLPHNEAGREILLVPTPGKHGWTVLHGRVGRPENPFRVALEYISSGNRSLSA
VDFFALKNCSEGTSPGSKMALQSSFTCWNGTVLQLGQACDFHQNCAQGEDEGQLCSKLPA
GFYCNFEDGFCGWTQSPLSPRVPRWQVKTLKDTHSQGHQGHALLLSTTDDPTSESATVTS
ATFPAPMKSSPCELRMSWLIRGVLKGNVSLVLVENKTGKEQSRTVWHVATNEGLSLWQWT
VLSLLDVTDRFWLQIVTWWGPGSRATVAFDNISISLDCYLTISGEEKMSLNAVPKSRNLF
EKNPNKEPKPWANISGPTPIFDPTVHWLFTTCGASGPHGPTQAQCNNAYQNSNLSVVVGS
EGPLRGIQIWKVPATDTYSISGYGAAGGKGGKNTMMRSHGVSVLGIFNLEKDDTLYILVG
QQGEDACPRANQLIQKVCVGENNVIEEEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPV
PLIIAAGGGGRAYGAKTETFHPERLENNSSVLGLNGNSGAAGGGGGWNDNTSLLWAGKSL
LEGAAGGHSCPQAMKKWGWETRGGFGGGGGGCSSGGGGGGYIGGNAASNNDPEMDGEDGV
SFISPLGILYTPALKVMEGHGEVNIKHYLNCSHCEVDECHMDPESHKVICFCDHGTVLAD
DGVSCIVSPTPEPHLPLSLILSVVTSALVAALVLAFSGIMIVYRRKHQELQAMQMELQSP
EYKLSKLRTSTIMTDYNPNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEVYEGQVS
GMPNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILL
ELMAGGDLKSFLRETRPRPNQPTSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCL
LTCPGAGRIAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFG
VLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNF
AIILERIEYCTQDPDVINTALPIEYGPVVEEEEKVPMRPKDPEGMPPLLVSPQSAKHEEA
SSAPQPSALAAPGPLVKKPSGAGAGAGAGPVPRGAADRGHVNMAFSQPNPPPELHKGPGS
RNKPTSLWNPTYGSWFTEKPAKKTHPPPGAEPQARAGAAEGGWTGPGAGPRRAEAALLLE
PSALSATMKEVPLFRLRHFPCGNVNYGYQQQGLPLEATAAPGDTVLKSKTKVTQPGP
NT seq 4854 nt   +upstreamnt  +downstreamnt
atgggagcccttgggttcctgtggctgctgccgccgctgcttttgacagcagcctcgtac
tccggagctgcaaccgatcagcgcgcgggttctccagcctcagggccgcctctgcagccc
cgggagccgctcagctattcgcgcctgcagaggaagagtctggcggtggacttcgtggtg
ccctcactcttccgcgtctatgcccgagacctgctgctgccgcagccaccgtccccctcg
gagcccggggctggcgggctggaggcgcggggatcactggctctggactgcgaccctctg
ctcaggttgctggggccatcgcctggaatctcctgggcagagggagccagttctcctagt
ccggaggcggctccgacgctgtccagggtgctgaagggcggctcggtgcgcaagctcagg
cgtgccaaacagctggtgctggagctgggcgaggagacgatccttgaaggctgcattggt
cccccagaggaggcggcggctgtggggatactccagttcaaccttagcgagctgttcagc
tggtggattctacacggcgaagggcggctgaggatccgcctgatgcctgagaagaaggca
tcggaagtgggcagggagggaaggctatccactgcgatccgagcctcccagccccgcctt
ctcttccagatcttcgggaccggtcacagctccttggaatcaccctcagaaatgccttct
cctcctggtaactttctatggaatctcacctggacaatgaaagactccttccctttcctt
tcccaccgcagtcgatatggtctggagtgcagcttcgattttccctgtgagctagaatac
tcccctcccctccacacccatgggaaccagagctggtcctggcgccgtgtgccctctgag
gaggcctcgaggatgaacttgttggatgggccagaggcagagcatttgaaagagatgccc
agaggctccttcctcctcctgaacacctctgcagattccaagcataccatcctgagcccc
tggatgaggagcagtagtgagcactgcacgctggctgtctcagtgcacagacatctacag
ccttctgggagatatgttgcccagctcctaccccacaatgaagctggaagagagattctt
ctggtgcctaccccggggaaacatggctggacagtgctgcatgggagagtcgggcgccca
gagaacccattccgagtggccctggaatacatctcgagtggaaaccggagcttgtctgcg
gtggatttctttgccctgaagaactgcagtgaaggaacatccccaggctccaagatggcc
ttgcagagttccttcacttgttggaacgggacagtcctccagctcgggcaagcctgtgac
ttccaccagaactgtgcccaaggagaagatgagggtcagctatgcagtaaacttcctgct
gggttttactgtaacttcgaggatggcttctgtggctggacccaaagtccactctcaccc
cgtgtgccccgatggcaagtgaagaccctgaaagatacccattcccagggccaccaaggc
catgccctgttgctcagcaccactgacgaccccacttcagaaagtgcaacagtgaccagt
gctacattccccgcaccaatgaagagctctccttgtgagctccggatgtcctggctcatc
cgtggggttctgaaaggaaatgtatctttggtgctggtggagaacaaaactggaaaggag
caaagccggaccgtctggcatgttgccaccaatgaaggcctaagcctgtggcagtggaca
gtgttgtcgctcctcgatgtgactgacaggttctggctgcaaatagtcacatggtggggc
ccaggatccagggcaaccgtggcatttgacaacatttccatcagcctcgactgctacctc
accatcagtggggaggagaaaatgtccctgaatgcagtacccaaatccagaaatctgttt
gagaaaaacccaaacaaggagccaaaaccctgggcaaacatatcaggaccaactcccatc
ttcgaccctacagttcactggctgttcaccacatgtggggccagtggccctcatggcccc
acacaggcacagtgcaacaacgcctaccagaactccaacctgagcgtggtggtgggaagt
gaagggcccttgaggggcatccagatttggaaagtgccagctactgacacctacagtatc
tcaggctatggagcagctggcggaaaaggtgggaagaacaccatgatgcggtcccatggc
gtgtctgtcctgggcatcttcaatctggagaaagatgacacgctctacatccttgtcggt
caacaaggggaagatgcctgtcccagggcaaaccaactaatccagaaagtatgtgtcggc
gagaacaatgtgatagaagaagagatccgagtgaacagaagcgttcacgagtgggcagga
ggaggaggaggtgggggtggagccacctacgtgtttaagatgaaagacggcgtgcccgtg
cccctgattattgcggccggcggtggtggcagggcctatggggccaagacagaaacgttc
cacccagagagactggagaataactcctcagttctagggctgaacggcaattccggagcc
gcaggtggtggaggcggctggaatgataacacttccttgctctgggccggaaagtctttg
ttggagggcgccgccggaggacattcctgcccccaggccatgaagaagtgggggtgggag
acaagagggggtttcggagggggtggaggggggtgctcctcaggtggaggaggcggagga
tatataggtggcaacgcagcatcaaacaatgaccccgaaatggatggggaagatggggtt
tccttcatcagtccattgggtatcctgtataccccggccttaaaagtgatggagggccat
ggggaagtgaatatcaagcactatctaaactgcagccactgtgaggtagacgaatgtcac
atggaccccgagagccacaaagtcatctgcttctgtgaccatgggaccgtgctggctgac
gatggtgtctcctgcattgtgtcgcccaccccggaaccccacctgccgctctcattgatc
ctctccgtcgtgacctctgccctggtggccgctctcgttctggcattctccggcatcatg
attgtgtaccgccggaagcaccaggagttgcaagctatgcagatggagctgcagagccct
gagtataagctgagcaagctacggacctcgaccatcatgacagactacaaccccaactac
tgctttgctggcaagacttcatccatcagtgacctgaaggaggtgcctcggaaaaacatc
accctcatccggggcctaggccatggcgcatttggggaggtgtatgaaggccaggtatct
ggaatgcccaatgacccaagccctctacaagtggctgtaaagacgctgccggaagtgtgt
tcagagcaagatgagctggacttcctcatggaagctctgatcatcagtaaattcaaccac
cagaacattgtccgctgcatcggggtgagtctgcaagccctgccccgcttcatcctgctg
gagctcatggctggtggagacctcaagtccttcctcagggagacacgtcctcgcccgaac
cagcccacctccctggccatgttggatcttctgcacgtagctcgggacattgcctgtggc
tgtcagtacctggaggaaaatcactttatccaccgcgatattgctgctagaaactgtctg
ctgacctgtccgggagctgggaggatagcgaagatcggagacttcgggatggcccgagat
atctacagggccagctactacagaaagggaggctgtgccatgctgccagtgaagtggatg
cccccggaggccttcatggaaggaatatttacttctaaaacagatacatggtcttttgga
gtgttgctgtgggaaatattttctcttggatatatgccataccccagcaagagcaaccag
gaagttctggagtttgtcaccagtggaggacggatggacccacctaagaactgccccgga
cctgtataccggataatgactcagtgctggcagcatcagcctgaggacagacccaacttt
gccatcattctggagaggatcgaatactgcacccaggaccccgatgtcatcaatacagct
ctgcccatcgaatatggccccgtagtagaggaggaggagaaagtgcccatgcgccccaaa
gaccctgaggggatgcctcctctgctggtgtctccccagtctgcgaagcacgaggaggcg
tcctcagccccccaaccctcagccctggcagcgccaggcccgctggtgaagaagccctcg
ggtgcaggcgcgggagcgggtgccggtccggtgccccgaggtgcagccgatcggggccac
gtgaacatggcgttctctcagcccaaccctcccccagagctgcacaaaggcccgggctcc
agaaacaagccgaccagcctgtggaaccccacctacggctcgtggttcaccgagaagcca
gccaaaaagacccatcccccaccgggcgcggagccgcaggcccgggcaggagcggcggag
ggtggctggaccgggccgggtgcggggccccgcagagccgaggctgcgctgctgctcgag
ccgtcggcgctcagcgccaccatgaaggaggtgcccctgttcaggctgcgccacttcccc
tgcggcaacgtcaactatggttaccagcaacagggtctccccttggaagccactgctgcc
ccgggggacaccgtgctgaaaagcaagactaaggtcacccagccagggccctga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (3)   
   KEGG PATHWAY (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (4)   
   UniProt (1)   
   RefSeq(pep) (3)   
DNA sequence (6)   
   RefSeq(nuc) (4)   
   GenBank (1)   
   EMBL (1)   
Protein domain (6)   
   Pfam (6)   
All databases (31)   

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