KEGG   Rattus norvegicus (rat): 29263Help
Entry
29263             CDS       T01003                                 

Gene name
Acvr2a, Acvr2, rActR-II
Definition
(RefSeq) activin A receptor type 2A
  KO
K04670  activin receptor type-2A [EC:2.7.11.30]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04060  Cytokine-cytokine receptor interaction
rno04350  TGF-beta signaling pathway
rno04550  Signaling pathways regulating pluripotency of stem cells
rno05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    29263 (Acvr2a)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    29263 (Acvr2a)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    29263 (Acvr2a)
 09160 Human Diseases
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    29263 (Acvr2a)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rno01001]
    29263 (Acvr2a)
Enzymes [BR:rno01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.30  receptor protein serine/threonine kinase
     29263 (Acvr2a)
Protein kinases [BR:rno01001]
 Receptor serine/threonine kinases (RSTK): TKL group
  TGFBR2 family [OT]
   29263 (Acvr2a)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Pkinase Pkinase_Tyr Activin_recp Pkinase_fungal FTA2 APH
Motif
Other DBs
NCBI-GeneID: 29263
NCBI-ProteinID: NP_113759
RGD: 70911
Ensembl: ENSRNOG00000005334
Vega: OTTRNOG00000002257
UniProt: P38444
Position
3q12
AA seq 513 aa AA seqDB search
MGAAAKLAFAVFLISCSSGAILGRSETQECLFFNANWERDRTNQTGVEPCYGDKDKRRHC
FATWKNISGSIEIVKQGCWLDDINCYDRTDCIEKKDSPEVYFCCCEGNMCNEKFSYFPEM
EVTQPTSNPVTPKPPYYNILLYSLVPLMLIAGIVICAFWVYRHHKMAYPPVLVPTQDPGP
PPPSPLLGLKPLQLLEVKARGRFGCVWKAQLLNEYVAIKIFPIQDKQSWQNEYEVYSLPG
MKHENILQFIGAEKRGTSVDVDLWLITAFHEKGSLSDFLKANVVSWNELCHIAETMARGL
AYLHEDIPGLKDGHKPAISHRDIKSKNVLLKNNLTACIADFGLALKFEAGKSAGDTHGQV
GTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELASRCTAADGPVDEYMLPFEEEIG
QHPSLEDMQEVVVHKKKRPVLRDYWQKHAGMAMLCETIEECWDHDAEARLSAGCVGERIT
QMQRLTNIITTEDIVTVVTMVTNVDFPPKESSL
NT seq 1542 nt NT seq  +upstreamnt  +downstreamnt
atgggagctgctgcaaagttggcgttcgccgtctttcttatctcttgctcttcaggtgct
atacttggcagatcggaaactcaggagtgtcttttctttaatgctaattgggaaagagac
agaaccaatcagactggtgttgagccttgctatggtgataaagacaaacgacgacattgt
tttgctacctggaagaatatttctggttccattgaaatagtaaagcaaggttgttggctg
gatgatatcaactgctatgacaggactgattgtatagaaaaaaaagacagccctgaagtg
tacttttgttgctgtgagggcaatatgtgtaatgaaaagttctcttattttccggagatg
gaagtcacacagcccacatcaaatcctgttaccccgaaaccaccctactacaacatcctg
ctgtattccttggtaccacttatgttaattgcggggattgtcatttgtgcgttttgggtg
tacagacatcacaagatggcctaccctcctgtacttgttcctactcaggaccctggacca
cctccaccttccccattactagggttgaagccattgcagctattggaagtgaaagcaagg
ggaagatttggttgtgtctggaaagcccagttgctcaatgagtatgtggctatcaaaata
tttccgatacaggacaaacagtcctggcagaatgaatatgaagtctatagtttacctggg
atgaagcatgaaaacatactacagttcattggtgcagagaaaagaggcaccagtgttgat
gtggacctgtggctaatcacggcttttcatgaaaagggctcactgtcagactttcttaag
gctaatgtggtctcttggaatgaactttgtcatattgcagaaaccatggctagaggattg
gcatatttacatgaggatatacctggcttaaaagatggccacaagcctgcaatatctcac
agggacatcaaaagtaaaaatgtgctgttgaaaaacaatctgacagcttgcattgctgac
tttgggttggccttaaagtttgaggctggcaagtctgcaggtgacacccatggccaggtt
ggtacccggaggtatatggctccagaggtgttagagggtgctataaacttccaaagggac
gcatttctgaggatagatatgtacgccatgggattagtcctgtgggaactggcttctcgt
tgtactgctgcagatggacctgtagatgagtacatgttgccatttgaggaggaaattggc
cagcatccatctcttgaagatatgcaggaagttgttgtgcataaaaaaaagaggcccgtt
ttaagagattattggcagaaacacgcaggaatggcaatgctctgtgaaacgatagaagaa
tgctgggatcatgatgcagaagccaggttatcagctggatgtgtaggtgaaagaattact
cagatgcaaagactaacaaatataattactacagaggacattgtaacagtggtcacaatg
gtgacaaatgttgactttcctcccaaagaatctagtctatga

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