KEGG   Rattus norvegicus (rat): 29487
Entry
29487             CDS       T01003                                 

Gene name
Gstt2
Definition
(RefSeq) glutathione S-transferase, theta 2
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00480  Glutathione metabolism
rno00980  Metabolism of xenobiotics by cytochrome P450
rno00982  Drug metabolism - cytochrome P450
rno00983  Drug metabolism - other enzymes
rno01100  Metabolic pathways
rno01524  Platinum drug resistance
rno05200  Pathways in cancer
rno05204  Chemical carcinogenesis
rno05225  Hepatocellular carcinoma
rno05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    29487 (Gstt2)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    29487 (Gstt2)
   00982 Drug metabolism - cytochrome P450
    29487 (Gstt2)
   00983 Drug metabolism - other enzymes
    29487 (Gstt2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    29487 (Gstt2)
   05204 Chemical carcinogenesis
    29487 (Gstt2)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    29487 (Gstt2)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    29487 (Gstt2)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    29487 (Gstt2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:rno02000]
    29487 (Gstt2)
Enzymes [BR:rno01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     29487 (Gstt2)
Transporters [BR:rno02000]
 Other transporters
  Pores ion channels [TC:1]
   29487 (Gstt2)
SSDB
Motif
Pfam: GST_N GST_N_3 GST_N_2 GST_C GST_C_3 GST_C_2 Oxidored_nitro
Other DBs
NCBI-GeneID: 29487
NCBI-ProteinID: NP_036928
RGD: 69362
Ensembl: ENSRNOG00000052415
UniProt: P30713 B6DYQ9
Position
20p12
AA seq 244 aa
MGLELYLDLLSQPSRAVYIFAKKNGIPFQLRTVDLLKGQHLSEQFSQVNCLKKVPVLKDG
SFVLTESTAILIYLSSKYQVADHWYPADLQARAQVHEYLGWHADNIRGTFGVLLWTKVLG
PLIGVQVPEEKVERNRNSMVLALQRLEDKFLRDRAFIAGQQVTLADLMSLEELIQPVALG
CNLFEGRPQLTAWRERVEAFLGAELCQEAHNPIMSVLGQAAKKTLPVPPPEAHASMMLRI
ARIP
NT seq 735 nt   +upstreamnt  +downstreamnt
atgggtttggagctctacctggacctgctgtcgcagcccagccgcgcggtctacatcttc
gccaagaagaatggcatcccctttcagttgcgtaccgtggatttactcaaagggcagcac
ttgagcgagcaattctcccaggtgaactgcttaaagaaagtgcctgtcctcaaagacgga
agcttcgtgttgaccgaaagcactgccatcttgatttacctgagttccaagtaccaggtg
gcagaccactggtacccggccgacctacaggcccgtgcccaagtccacgaatacctgggt
tggcatgccgacaacatccgtggcacctttggagtactcctgtggaccaaggtgttgggg
ccactcattggggtccaggttcccgaggaaaaggtggaacggaacagaaatagtatggtc
ttggctctgcaacgtctggaggacaagttcctcagggacagggccttcattgctggccag
caggtgacgctagcggatctcatgtctctagaggagttgatacagccggtggctcttggc
tgtaatctgtttgaggggcggcctcaactgacagcgtggcgagagagggtggaggcgttc
ttgggtgctgagctatgtcaggaggcgcacaaccccatcatgagcgtcctgggacaggca
gccaagaaaacattaccagtaccccctccggaggcccatgccagcatgatgcttcgaatt
gccaggattccctga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (10)   
   KEGG PATHWAY (10)   
Chemical substance (45)   
   KEGG COMPOUND (45)   
Chemical reaction (23)   
   KEGG ENZYME (1)   
   KEGG REACTION (22)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (9)   
   RefSeq(nuc) (1)   
   GenBank (4)   
   EMBL (4)   
Protein domain (7)   
   Pfam (7)   
All databases (108)   

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