KEGG   Rattus norvegicus (rat): 29487
Entry
29487             CDS       T01003                                 

Gene name
Gstt2
Definition
(RefSeq) glutathione S-transferase, theta 2
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00480  Glutathione metabolism
rno00980  Metabolism of xenobiotics by cytochrome P450
rno00982  Drug metabolism - cytochrome P450
rno00983  Drug metabolism - other enzymes
rno01100  Metabolic pathways
rno01524  Platinum drug resistance
rno05200  Pathways in cancer
rno05204  Chemical carcinogenesis
rno05225  Hepatocellular carcinoma
rno05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    29487 (Gstt2)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    29487 (Gstt2)
   00982 Drug metabolism - cytochrome P450
    29487 (Gstt2)
   00983 Drug metabolism - other enzymes
    29487 (Gstt2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    29487 (Gstt2)
   05204 Chemical carcinogenesis
    29487 (Gstt2)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    29487 (Gstt2)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    29487 (Gstt2)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    29487 (Gstt2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:rno02000]
    29487 (Gstt2)
Enzymes [BR:rno01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     29487 (Gstt2)
Transporters [BR:rno02000]
 Other transporters
  Pores ion channels [TC:1]
   29487 (Gstt2)
SSDB
Motif
Pfam: GST_N GST_N_3 GST_N_2 GST_C GST_C_3 GST_C_2 Oxidored_nitro
Other DBs
NCBI-GeneID: 29487
NCBI-ProteinID: NP_036928
RGD: 69362
Ensembl: ENSRNOG00000052415
UniProt: P30713 B6DYQ9
Position
20p12
AA seq 244 aa
MGLELYLDLLSQPSRAVYIFAKKNGIPFQLRTVDLLKGQHLSEQFSQVNCLKKVPVLKDG
SFVLTESTAILIYLSSKYQVADHWYPADLQARAQVHEYLGWHADNIRGTFGVLLWTKVLG
PLIGVQVPEEKVERNRNSMVLALQRLEDKFLRDRAFIAGQQVTLADLMSLEELIQPVALG
CNLFEGRPQLTAWRERVEAFLGAELCQEAHNPIMSVLGQAAKKTLPVPPPEAHASMMLRI
ARIP
NT seq 735 nt   +upstreamnt  +downstreamnt
atgggtttggagctctacctggacctgctgtcgcagcccagccgcgcggtctacatcttc
gccaagaagaatggcatcccctttcagttgcgtaccgtggatttactcaaagggcagcac
ttgagcgagcaattctcccaggtgaactgcttaaagaaagtgcctgtcctcaaagacgga
agcttcgtgttgaccgaaagcactgccatcttgatttacctgagttccaagtaccaggtg
gcagaccactggtacccggccgacctacaggcccgtgcccaagtccacgaatacctgggt
tggcatgccgacaacatccgtggcacctttggagtactcctgtggaccaaggtgttgggg
ccactcattggggtccaggttcccgaggaaaaggtggaacggaacagaaatagtatggtc
ttggctctgcaacgtctggaggacaagttcctcagggacagggccttcattgctggccag
caggtgacgctagcggatctcatgtctctagaggagttgatacagccggtggctcttggc
tgtaatctgtttgaggggcggcctcaactgacagcgtggcgagagagggtggaggcgttc
ttgggtgctgagctatgtcaggaggcgcacaaccccatcatgagcgtcctgggacaggca
gccaagaaaacattaccagtaccccctccggaggcccatgccagcatgatgcttcgaatt
gccaggattccctga

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