KEGG   Rattus norvegicus (rat): 296078Help
Entry
296078            CDS       T01003                                 

Gene name
Pak6
Definition
(RefSeq) p21 (RAC1) activated kinase 6
  KO
K05735  p21-activated kinase 6 [EC:2.7.11.1]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04012  ErbB signaling pathway
rno04014  Ras signaling pathway
rno04360  Axon guidance
rno04510  Focal adhesion
rno04660  T cell receptor signaling pathway
rno04810  Regulation of actin cytoskeleton
rno05170  Human immunodeficiency virus 1 infection
rno05211  Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    296078 (Pak6)
   04012 ErbB signaling pathway
    296078 (Pak6)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    296078 (Pak6)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    296078 (Pak6)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    296078 (Pak6)
  09158 Development and regeneration
   04360 Axon guidance
    296078 (Pak6)
 09160 Human Diseases
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    296078 (Pak6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    296078 (Pak6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rno01001]
    296078 (Pak6)
Enzymes [BR:rno01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     296078 (Pak6)
Protein kinases [BR:rno01001]
 Serine/threonine kinases: STE group
  STE20 family
   296078 (Pak6)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Pkinase Pkinase_Tyr PBD Kinase-like Pkinase_fungal Kdo
Motif
Other DBs
NCBI-GeneID: 296078
NCBI-ProteinID: NP_001099968
RGD: 1306213
Ensembl: ENSRNOG00000007925
UniProt: D3ZQ51
Position
3q35
AA seq 681 aa AA seqDB search
MFRKKKKKRPEISAPQNFQHRVHTSFDPKEGKFVGLPPQWQNILDTLRRPKPVVDPSRIT
RVQLQPMKTVVRGSSVPTEGYISGLLNDIQKLSAISSNTLRGRSPTSRRRAQSLGLLGDD
QWAADPDMYLQSPQSERTDPHGVYLSCNGGTPAGHRQTPWPEPQSPQALPNGMAAKAQSL
GPAEFQGASQRCLQLGACLQSSPPGTSPPMATGRRGVKVTKHSSEEARPQSCLVGSAIGR
PGGEGSPSPKTQESSLKHRLFRSMFLSTPATGSASSSKPVPLPQNKLNSAFRPPQKDSSS
NLVAKAQSLPSDQPTGTFSPLTTSDTSSPQKSLRTAPATGPLPGRSSPAGSPRTRHAQIS
TSNLYLPQDPTVAKGALGGEDTGIVTHEQFKAALRMVVDQGDPRLLLDSYVKIGEGSTGI
VCLAREKHSGRQVAVKMMDLRKQQRRELLFNEVVIMRDYQHLNVVEMYKSYLVGEELWVL
MEFLQGGALTDIISQVRLNEEQIATVCEAVLQALAYLHAQGVIHRDIKSDSILLTLDGRV
KLSDFGFCAQISKDVPKRKSLVGTPYWMAPEVISRSLYATEVDIWSLGIMVIEMVDGEPP
YFSDSPVQAMKRLRDSPPPKLKNSYKVSPVLRDFLERMLVREPQERATAQELLDHPFLLQ
TGLPECLVPLIQLYRKQTSTC
NT seq 2046 nt NT seq  +upstreamnt  +downstreamnt
atgttccgaaagaagaagaagaaacgccctgagatatcagccccacagaacttccagcac
cgtgttcacacctcatttgaccccaaggaaggcaagttcgtgggcctgcccccacaatgg
cagaacatcctggatactctgaggcggcccaagcctgtggtggatccttctcgaatcaca
cgggtgcagttgcagcccatgaagacggtagtacggggcagctcagtgcccacagagggc
tacatctccgggctgctcaatgacattcagaagttgtcagctatcagctccaacactctg
cgtggacgcagccccaccagccggcggcgggcacagtccctggggctgctaggagatgat
cagtgggcggctgacccggatatgtacctccaaagtcctcagtctgagcgcactgatccc
catggcgtctacctcagctgtaatgggggcacaccagcaggtcacaggcaaacgccatgg
ccagaaccacagagcccacaggccctgcccaatggcatggctgccaaggcacagtcgctg
ggccccgctgagttccagggtgcctcccaacgctgcctgcagctgggtgcctgcctacag
agttccccacctggtacctcaccccctatggccacagggaggcgtggggtgaaggttacc
aagcatagctcggaagaggctcgaccacaatcttgcctggtgggctcagccattggcaga
ccaggtggagaaggcagccccagccctaagacccaggaaagcagcctcaagcaccggctc
ttccgcagcatgttcctgtccactcccgccacaggctctgcaagcagcagcaagccggtc
cctctgccacagaacaagctcaattctgctttccgaccaccacaaaaagattcctcttca
aacctggtagccaaggcccagtccttgccctcagatcagcccacggggaccttcagtcct
ctgaccacctcagataccagcagtccccagaagtccctccgcacagccccagccactggt
ccacttccaggccggtcttctccagcaggctccccccgcacccggcatgcccagatcagc
accagcaatctatacctgccccaggaccccacagtggccaagggggccctgggtggcgaa
gacacaggcatcgtaacacatgagcagttcaaagctgcgctcaggatggtggtggaccag
ggtgaccctcggctgctgctggacagctatgtgaagattggggagggctccacgggcatt
gtgtgtctggcccgggagaagcattcaggtcgccaggtagcagtcaagatgatggacctc
agaaagcagcaacgcagggaactgctctttaatgaggtggtgatcatgcgtgactaccag
cacctcaatgtggtggagatgtacaagagttacctggtaggagaggagctgtgggtgctg
atggagttcctgcagggcggggccctcacagacatcatctcccaagtcagactcaatgag
gaacagattgctactgtgtgtgaagctgtgcttcaggccttggcttacctgcacgcccag
ggtgtcatccaccgagacatcaagagtgattccatcctgctgacccttgatggcagggtg
aagctctcagactttgggttctgtgctcagatcagcaaagatgtccccaagagaaagtct
ctcgtaggaactccatactggatggctcctgaggtgatctccagatccctgtacgctact
gaggtggatatctggtctctgggcatcatggtgattgagatggtggatggagaaccccct
tacttcagcgactccccagtgcaagccatgaagaggctccgggacagccccccacccaag
ctaaagaactcttacaaggtctctccagtgctgcgagacttcctggaacgaatgctggta
cgggaaccccaagagagagccacagcccaggagctcctggatcacccctttctgctgcag
acggggctgcccgagtgtctggtgcctctgatacagctctaccgcaagcagacctccacc
tgctga

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