KEGG   Rattus norvegicus (rat): 29627
Entry
29627             CDS       T01003                                 
Symbol
Gria2
Name
(RefSeq) glutamate receptor 2 isoform 2 precursor
  KO
K05198  glutamate receptor 2
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04024  cAMP signaling pathway
rno04080  Neuroactive ligand-receptor interaction
rno04082  Neuroactive ligand signaling
rno04713  Circadian entrainment
rno04720  Long-term potentiation
rno04723  Retrograde endocannabinoid signaling
rno04724  Glutamatergic synapse
rno04728  Dopaminergic synapse
rno04730  Long-term depression
rno05014  Amyotrophic lateral sclerosis
rno05016  Huntington disease
rno05017  Spinocerebellar ataxia
rno05022  Pathways of neurodegeneration - multiple diseases
rno05030  Cocaine addiction
rno05031  Amphetamine addiction
rno05033  Nicotine addiction
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    29627 (Gria2)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    29627 (Gria2)
   04082 Neuroactive ligand signaling
    29627 (Gria2)
 09150 Organismal Systems
  09156 Nervous system
   04724 Glutamatergic synapse
    29627 (Gria2)
   04728 Dopaminergic synapse
    29627 (Gria2)
   04720 Long-term potentiation
    29627 (Gria2)
   04730 Long-term depression
    29627 (Gria2)
   04723 Retrograde endocannabinoid signaling
    29627 (Gria2)
  09159 Environmental adaptation
   04713 Circadian entrainment
    29627 (Gria2)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    29627 (Gria2)
   05016 Huntington disease
    29627 (Gria2)
   05017 Spinocerebellar ataxia
    29627 (Gria2)
   05022 Pathways of neurodegeneration - multiple diseases
    29627 (Gria2)
  09165 Substance dependence
   05030 Cocaine addiction
    29627 (Gria2)
   05031 Amphetamine addiction
    29627 (Gria2)
   05033 Nicotine addiction
    29627 (Gria2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:rno04040]
    29627 (Gria2)
Ion channels [BR:rno04040]
 Ligand-gated channels
  Glutamate (ionotropic)
   29627 (Gria2)
SSDB
Motif
Pfam: ANF_receptor Lig_chan Lig_chan-Glu_bd SBP_bac_3 Peripla_BP_6
Other DBs
NCBI-GeneID: 29627
NCBI-ProteinID: NP_001077280
RGD: 61862
Ensembl: ENSRNOG00000054204
UniProt: P19491
Structure
Position
2:complement(168247490..168367616)
AA seq 883 aa
MQKIMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTP
HIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDG
THPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINV
GNINNDKKDETYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANL
GFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSALT
YDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNI
KFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTT
ILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKI
WNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLD
PLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWF
SLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDL
SKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGK
YAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLL
DKLKNKWWYDKGECGSGGGDSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSR
AEAKRMKVAKNPQNINPSSSQNSQNFATYKEGYNVYGIESVKI
NT seq 2652 nt   +upstreamnt  +downstreamnt
atgcaaaagattatgcatatttctgtcctcctttctcctgttttatggggactgattttt
ggtgtctcttctaacagcatacagataggggggctatttccaaggggcgctgatcaagaa
tacagtgcatttcgggtagggatggttcagttttccacttcggagttcagactgacaccc
catatcgacaatttggaggtagccaacagtttcgcagtcaccaatgctttctgctcccag
ttttcaagaggagtctacgcaatttttggattttatgacaagaagtctgtaaataccatc
acatcattctgtgggacactccatgtgtccttcatcacacctagcttcccaacagatggc
acacatccatttgtcatccagatgcgacctgacctcaaaggagcactccttagcttgatt
gagtactaccaatgggacaagttcgcatacctctatgacagtgacagaggcttatcaaca
ctgcaagctgttctggattctgctgcagagaagaagtggcaggtgactgctatcaatgtg
gggaacatcaacaatgacaagaaagatgagacctacagatcgctctttcaagatctggag
ttaaaaaaagaacggcgtgtaatcctggactgtgaaagggataaagtaaatgacattgtg
gaccaggttattaccattggaaaacatgttaaagggtaccattatatcattgcaaatctg
ggattcactgatggggacctgctgaaaattcagtttggaggagcaaatgtctctggattt
cagattgtagactacgacgattccctggtgtctaaatttatagaaagatggtcaacactg
gaagagaaagaataccctggagcacacacagcgacaattaagtatacttcggccctgacg
tatgatgctgtccaagtgatgactgaagcattccgtaaccttcggaagcagaggattgaa
atatcccggagaggaaatgcaggagattgtttggccaacccagctgtgccctggggacaa
ggggtcgaaatagaaagggccctcaagcaggttcaagttgaaggcctctctggaaatata
aagtttgaccagaatggaaaacgaataaactacacaattaacatcatggagctcaaaaca
aatggaccccggaagattgggtactggagtgaagtggataaaatggttgtcaccctaact
gagctcccatcaggaaatgacacgtctgggcttgaaaacaagactgtggtggtcaccaca
atattggaatctccatatgttatgatgaagaaaaatcatgaaatgcttgaagggaatgag
cgttacgagggctactgtgttgacttagctgcagaaattgctaaacactgtgggttcaag
tacaagctgactattgttggggatggcaagtatggggccagggatgccgacaccaaaatt
tggaatggtatggttggagagcttgtctacgggaaagctgacattgcaattgctccatta
actatcactctcgtgagagaagaggtgattgacttctccaagcccttcatgagtcttgga
atctctatcatgatcaagaagcctcagaagtccaaaccaggagtgttttcctttcttgat
cctttagcctatgagatctggatgtgcattgtgtttgcctacattggggtcagtgtagtt
ttattcctggtcagcagatttagcccctacgagtggcacactgaggaatttgaagatgga
agagaaacacaaagtagtgaatcaactaatgaatttgggatttttaatagtctctggttt
tccttgggtgcctttatgcggcaaggatgcgatatttcgccaagatccctctctgggcgc
attgttggaggtgtgtggtggttctttaccctgatcataatctcctcctacacggctaac
ttagctgccttcctgactgtagagaggatggtgtctcccatcgaaagtgctgaggatctg
tctaagcaaacagaaattgcttatggaacattagactctggctccactaaagagtttttc
aggagatctaaaatcgcagtgtttgataaaatgtggacttatatgaggagtgcagagccc
tctgtgtttgtgaggactaccgcagaaggagtagccagagtccggaaatccaaaggaaag
tatgcctacttgctggagtccacaatgaacgagtacatcgagcagaggaagccttgtgac
accatgaaagtgggaggaaacttggattccaaaggctacggcatcgccacacctaaagga
tcctcattaggaaatgcggttaacctcgcagtactaaaactgaatgaacaaggcctgttg
gacaaattgaaaaacaaatggtggtacgacaaaggagagtgcggcagcgggggaggtgat
tccaaggaaaagaccagtgccctcagtctgagcaacgttgctggagtattctacatcctt
gtcgggggccttggtttggcaatgctggtggctttgattgagttctgttacaagtcaagg
gccgaggcgaaacgaatgaaggtggcaaagaatccacagaatattaacccatcttcctcg
cagaattcccagaattttgcaacttataaggaaggttacaacgtatatggcatcgagagt
gttaaaatttag

  All links  
Gene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (14)   
   RefSeq(nuc) (2)   
   GenBank (6)   
   EMBL (6)   
3D Structure (311)   
   PDB (311)   
Protein domain (5)   
   Pfam (5)   
All databases (339)   

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