KEGG   Rattus norvegicus (rat): 308449
Entry
308449            CDS       T01003                                 

Gene name
Hipk4
Definition
(RefSeq) homeodomain-interacting protein kinase 4
  KO
K08826  homeodomain interacting protein kinase [EC:2.7.11.1]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04218  Cellular senescence
Brite
KEGG Orthology (KO) [BR:rno00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    308449 (Hipk4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rno01001]
    308449 (Hipk4)
Enzymes [BR:rno01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     308449 (Hipk4)
Protein kinases [BR:rno01001]
 Serine/threonine kinases: CMGC group
  DYRK family [OT]
   308449 (Hipk4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr APH Kinase-like TCAD9 Kdo Pox_ser-thr_kin RIO1
Other DBs
NCBI-GeneID: 308449
NCBI-ProteinID: NP_001019947
RGD: 1307541
Ensembl: ENSRNOG00000020835
UniProt: Q4V793
Position
1
AA seq 616 aa
MATIQSETDCYDIIEVLGKGTFGEVAKGWRRSTGEMVAIKILKNDAYRSRIIKNELKLLR
CVRGLDPDEAHVIRFLEFFHDALKFYLVFELLEQNLFEFQKENNFAPLPARHIRTVTLQV
LRALARLKELAIIHADLKPENIMLVDQTRCPFRVKVIDFGSASIFSEVRYVKEPYIQSRF
YRAPEILLGLPFCEKVDVWSLGCVMAELHLGWPLYPGNNEYDQVRYICETQGLPKPHLLH
AARKAHHFFKRNPHPDATNPWQLKSSADYLAETKVRPLERRKYMLKSLDQIETVNGGGAV
NRLSFPDREALAEHADLKSMVELIKRMLTWESHERISPSAALRHPFVSMQQLRSAHEATR
YYQLSLRGCRLSLQVDGKPPPPVIANAEDGPPYYRLAEEEETAGLGGVTGSGSFFREDKA
PGMQRAIDQLDDLSLQEARRGLWSDTRADMVSDMLAPLKVATTSHRVPDSGPEPILAFYG
SRLTGRHKARKAPAGSKSDSNFSNLIRLSQASPEDAGSCRGSGWEEGEGHTTSTEPSAIP
QREGDGPSIKDRPMDAERSGPELFDPSGCPGEWLNEPEWTLEGIRGSRAQGLPARHPHPH
GPPRTTSFLQHVGGHH
NT seq 1851 nt   +upstreamnt  +downstreamnt
atggccaccatccagtcagagactgactgttacgacatcattgaagtcctgggcaagggc
acttttggagaggtggccaagggctggcgtcggagtacaggagaaatggtggccatcaag
atcttgaagaacgacgcgtaccgaagccgtatcatcaagaatgagttgaagctgctgcgc
tgtgtacgaggcctggaccccgacgaggcccacgtcatccgcttccttgaattcttccat
gatgccctcaagttctacctggtctttgagctattggagcaaaacctctttgagttccag
aaagagaacaacttcgcacccctccctgccaggcacatccgaactgtcacactgcaggtc
ctaagagcgctggcccggctcaaggagttggctatcatccatgctgacctcaagccagaa
aacattatgttggtagatcagacccgctgccccttcagggtaaaggtgatcgactttggc
tcggccagcatattcagtgaggtgcgctatgtgaaggagccttacatccagtcccgcttc
tacagggccccagagatcctgttggggttgccgttctgcgagaaggtggacgtgtggtct
ctgggctgtgtcatggctgagttacacctgggctggcctctctacccaggcaacaatgag
tatgaccaggtgcgctacatctgtgagacccagggcttacccaagccccatctgctgcat
gcggcccgcaaggctcaccacttcttcaagcgtaacccccaccccgatgccaccaacccc
tggcagctcaagtcctctgctgactacctagctgagaccaaggtacgcccactggagcgc
cgcaagtacatgctcaaatccttggaccaaattgagacggtgaatggtggcggcgctgtg
aatcggttgagttttccagaccgggaggcactggcggaacacgcggacctcaagagcatg
gtggagctgatcaaacgcatgctgacatgggagtctcacgagcgcatcagtcccagcgcg
gccctgcgccaccccttcgtgtccatgcagcagctgcgtagtgcccacgaggccacccgc
tactaccagctgtccctccgaggctgtcggctgtccctgcaggtggacggcaagccaccc
ccacctgtcatagccaacgcagaggacgggcctccctactaccgcctggctgaggaggag
gagactgcaggcctgggtggtgtgaccggcagtgggtccttcttcagggaggacaaggct
cccggaatgcagagagccatcgaccagctcgatgacctgagtctgcaggaggcccgccgg
gggctgtggagcgacacgcgggccgacatggtctctgacatgctggctccactcaaagta
gccactaccagccatcgagtccccgactcgggcccggagcctatcctggccttctacggc
agccgcttgactggccgccataaggcccgcaaggccccagcaggctccaaatccgactcc
aacttcagtaacctcatccggctgagccaggcctcacctgaggatgcggggtcctgtagg
ggcagtggttgggaagaaggagaaggccacacgacttccacagagccgtctgccatccca
caacgggaaggagatggacccagcatcaaagacaggcccatggatgctgagaggtcaggc
cctgagctctttgatcccagcggctgtcctggagagtggctaaatgaaccagaatggacc
ctagagggcatccgggggtctcgagctcaagggcttccagctcgccatccccacccacac
gggccgcccaggaccaccagctttctgcagcatgttggagggcaccactga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (3)   
   RefSeq(nuc) (1)   
   GenBank (1)   
   EMBL (1)   
Protein domain (8)   
   Pfam (8)   
All databases (26)   

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KEGG   Rattus norvegicus (rat): 362342
Entry
362342            CDS       T01003                                 

Gene name
Hipk2
Definition
(RefSeq) homeodomain-interacting protein kinase 2
  KO
K08826  homeodomain interacting protein kinase [EC:2.7.11.1]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04218  Cellular senescence
Brite
KEGG Orthology (KO) [BR:rno00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    362342 (Hipk2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rno01001]
    362342 (Hipk2)
Enzymes [BR:rno01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     362342 (Hipk2)
Protein kinases [BR:rno01001]
 Serine/threonine kinases: CMGC group
  DYRK family [OT]
   362342 (Hipk2)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo Pkinase_fungal TCAD9 APH Pox_ser-thr_kin
Other DBs
NCBI-GeneID: 362342
NCBI-ProteinID: NP_001102092
RGD: 1309349
Ensembl: ENSRNOG00000007034
UniProt: D3ZN85
Position
4
AA seq 1195 aa
MAPVYEGMASHVQVFSPHTLQSSAFCSVKKLKVEPSSNWDMTGYGSHSKVYSQSKNIPPS
QPASTTVSTSLPIPNPSLPYEQTIIFPGSTGHIVVTSASSTSVTGQVLGGPHNLMRRSTV
SLLDTYQKCGLKRKSEEIENTSSVQIIEEHPPMIQNNASGATVATATTSTATSKNSGSNS
EGDYQLVQHEVLCSMTNTYEVLEFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQG
QIEVSILARLSTESADDYNFVRAYECFQHKNHTCLVFEMLEQNLYDFLKQNKFSPLPLKY
IRPVLQQVATALMKLKSLGLIHADLKPENIMLVDPSRQPYRVKVIDFGSASHVSKAVCST
YLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGASEYDQIRYISQTQGLP
AEYLLSAGTKTTRFFNRDTDSPYPLWRLKTPDDHEAETGIKSKEARKYIFNCLDDMAQVN
MTTDLEGSDMLVEKADRREFIDLLKKMLTIDADKRITPIETLNHPFVTMTHLLDFPHSTH
VKSCFQNMEICKRRVNMYDTVNQSKTPFITHVAPSTSTNLTMTFNNQLTTVHNQAPTSTS
ATLSLANPEVSILNYQSTLYQPSAASMAAVAQRSMPLQTGTAQICARPDPFQQALIVCPP
GFQGLQASPSKHAGYSVRMENAVPIVTQAPGAQPLQIQPGLLAQAWPGGAQQILLPPAWQ
QLTGVATHTSVQHAAVIPETMAGTQQLADWRNTHAHGSHYNPIMQQPALLTGHVTLPAAQ
PLNVGVAHVMRQQPTSTTSSRKSKQHQSSARNVSTCEVTSSQAISSPQRSKRVKENTPPR
CAMVHSSPACSTSLTCGWGDGASSTTRDRQRQTIVIPDTPSPTVSVITISSDTDEEEEQK
HAPTSTVSKQRKNVISCVTVHDSPYSDSSSNTSPYSVQQRTGHNGTNTLDTKGGLENHCT
GNPRTIIVPPLKTQASEVLVECDSLGPAISTGHHSSSFKSKSSSTVTSTSGHSSGSSSGA
IAYRQQRPGPHFQQQQPLNLSQAQQHMAADRTGSHRRQQAYITPTMAQAPYTFPHSSPSH
GTVHPHLAAAAHLPAQPHLYTYTAPTALGSTSTVAHLVASQGSARHTVQHTAYPASIVHQ
VPVSMGPRVLPSPTIHPSQYPAQFAHQTYISASPASTVYTGYPLSPAKVNQYPYI
NT seq 3588 nt   +upstreamnt  +downstreamnt
atggcccccgtgtacgaaggtatggcctcacatgtgcaagttttctcccctcacaccctt
caatcaagtgccttctgtagtgtgaagaaactaaaagtagagccaagttccaactgggac
atgactgggtacggctcccacagcaaagtgtacagccagagcaagaacataccaccttct
cagccagcctccacaaccgtcagcacctccttgccaatcccaaacccaagcctaccttac
gagcagaccatcatcttcccaggaagtactggacacatagttgtaacatcagcaagtagc
acttctgtcaccgggcaagtcctcggtggaccacataacctaatgcgtcgaagcactgtg
agcctccttgacacctaccaaaaatgtggactcaagcgcaagagtgaggagattgagaac
acaagcagcgtgcagatcattgaggagcatccacccatgattcagaataatgccagcggg
gccactgtcgccactgccaccacatccactgccacctccaaaaacagtggctccaacagt
gaaggtgactatcagctggtgcagcatgaagtgctgtgctctatgacaaacacctatgag
gttttagagttcttggggcgagggacatttgggcaagtggtcaagtgctggaaacggggc
accaatgaaattgtggccattaagatcctaaagaaccacccatcctatgcccggcaaggc
cagattgaagtgagcatcctggcccggctgagcacggagagcgctgatgactacaatttt
gtgcgggcctatgagtgcttccagcacaagaatcacacatgcttagtctttgagatgttg
gagcagaacctctatgactttctgaaacagaacaagtttagtcccttgcccctcaagtat
attcgcccagtcctccagcaggtagccacagccctgatgaaactcaaaagcctgggtctt
atccatgctgacctcaaaccagaaaacatcatgctggtggatccatccagacaaccatac
cgagtgaaggtcattgactttggttcagctagtcatgtgtccaaagctgtctgttctacg
tacttgcaatccagatactacagggcccctgaaatcatccttggtttgccattctgtgag
gcaattgacatgtggtccctgggttgtgtcattgctgagctgttcctgggctggccatta
tacccaggtgcttctgagtatgatcagattcggtatatttcacaaacacagggtttacca
gctgaatatttattaagtgcagggacaaagacaactaggtttttcaaccgtgacacagac
tcaccgtatcctttgtggaggctaaagacaccagatgaccatgaagcagagacggggatt
aaatcaaaagaagcaagaaagtacattttcaactgtttggatgacatggcccaggtgaac
atgacaacagatttggaagggagtgacatgttagtagagaaggcagaccggcgggagttc
attgacctgttaaagaagatgctgaccatagatgctgataagaggatcactcccattgaa
actctgaaccacccctttgtcaccatgacgcacctactggattttcctcatagtactcat
gtcaaatcttgtttccaaaacatggagatttgcaagcgccgggtgaatatgtatgacaca
gtgaaccagagcaaaacacctttcatcacacatgtggcccccagcacatctaccaacttg
accatgacctttaacaaccagctgaccactgtccacaaccaggctcccacctccaccagt
gccactctttccttagccaatcccgaagtctccatactaaactaccaatctacactctac
cagccctcagcggcatccatggccgcagtggcccagcggagcatgcccctgcagacggga
acagcccaaatttgtgcccggcctgaccctttccagcaagctctcatcgtgtgtccccct
ggcttccaaggcctgcaggcctctccctccaagcacgctggctactcagtgcggatggaa
aatgctgttcccatcgtcactcaggctccgggcgctcagcctcttcagatccagccaggt
ctgcttgctcaggcctggccaggtggggcccaacagatcctccttcctccagcatggcag
cagctcactggcgtggctacccacacatccgtacagcacgcagctgtgattcccgagacc
atggcaggcactcagcaactggctgactggagaaacacacatgctcacggaagccattac
aatcccatcatgcagcagcctgcactcttgactggtcatgtgacccttccagctgcccag
cccttaaatgtgggtgtagcccacgtgatgagacagcaaccaaccagcaccacctcctcc
aggaagagtaagcagcaccaatcatcagcgagaaatgtctccacctgtgaagtgacctct
tcccaggctatcagctcccctcagcgatccaagcgtgtcaaggagaacactcccccgagg
tgtgcaatggtacacagcagcccagcttgcagcacctcactcacctgtgggtggggtgac
ggggcctccagcaccacccgggaccgacagcggcagaccattgtcatccccgacaccccg
agccccacagtcagtgtcatcaccatcagcagcgacacagatgaggaggaggaacagaag
cacgcccccaccagcacagtctccaagcaaagaaaaaatgtcatcagctgtgtcacagtc
catgattctccctactctgactcctccagcaacaccagcccctactcggtgcagcagcgc
acagggcacaacggcaccaacaccttggacaccaaggggggcctagagaaccactgcacc
ggcaacccccgcaccatcatcgtacccccactgaagacgcaggccagtgaagtgttggta
gaatgtgacagcctagggccagcaatcagtaccggtcaccattcatcctccttcaagtcc
aagtcctccagcaccgtgacctccaccagtggccactcttcagggagctcgtcaggagcc
atcgcctaccgtcaacagcggccaggcccccacttccagcagcagcagcccctcaatctc
agccaggctcagcagcacatggctgcagaccgcactgggagtcaccgtcggcagcaggcc
tacatcactcctaccatggctcaggctccgtacaccttcccgcacagcagccccagccat
ggcactgttcacccccacctggctgcggctgcccacctccctgcccagcctcacctctac
acctacacagcgcccacagccctaggctccaccagcactgtagcccacctggtggcatcc
caaggctcagcacgacacaccgtgcagcacactgcctatccggccagcatcgtccaccag
gtccccgtgagcatggggccccgggtcctgccctcgcccaccattcaccccagtcagtat
ccggcccagtttgcccaccagacctatatcagcgcctcgccagcctccaccgtctacact
ggatatccactgagtcctgccaaggtcaaccaatacccttacatataa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (3)   
   RefSeq(nuc) (1)   
   GenBank (1)   
   EMBL (1)   
Protein domain (7)   
   Pfam (7)   
All databases (24)   

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KEGG   Rattus norvegicus (rat): 365895
Entry
365895            CDS       T01003                                 

Gene name
Hipk1
Definition
(RefSeq) homeodomain-interacting protein kinase 1
  KO
K08826  homeodomain interacting protein kinase [EC:2.7.11.1]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04218  Cellular senescence
Brite
KEGG Orthology (KO) [BR:rno00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    365895 (Hipk1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rno01001]
    365895 (Hipk1)
Enzymes [BR:rno01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     365895 (Hipk1)
Protein kinases [BR:rno01001]
 Serine/threonine kinases: CMGC group
  DYRK family [OT]
   365895 (Hipk1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo TCAD9 Pkinase_fungal APH Pox_ser-thr_kin GP24_25
Other DBs
NCBI-GeneID: 365895
NCBI-ProteinID: NP_001094456
RGD: 1304941
Ensembl: ENSRNOG00000019333
UniProt: F1M8I6
Position
2
AA seq 1211 aa
MASQLQVFSPPSVSSSAFCSAKKLKIEPSGWDVSGQSSNDKYYTHSKTLPATQGQASSSH
QVANFNIPAYDQGLLLQAPAVEHIVVTAADSSGSAATATFQSSQTLTHRSNVSLLEPYQK
CGLKRKSEEVDSNGSVQIIEEHPPLMLQNRTVVGAAATTTTVTTKSSSSSGEGDYQLVQH
EILCSMTNSYEVLEFLGRGTFGQVAKCWKRSTKEIVAIKILKNHPSYARQGQIEVSILSR
LSSENADEYNFVRSYECFQHKNHTCLVFEMLEQNLYDFLKQNKFSPLPLKYIRPILQQVA
TALMKLKSLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKAVCSTYLQSRYYRA
PEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGASEYDQIRYISQTQGLPAEYLLSAGT
KTTRFFNRDPNLGYPLWRLKTPEEHELETGIKSKEARKYIFNCLDDMAQVNMSTDLEGTD
MLAEKADRREYIDLLKKMLTIDADKRVTPLKTLNHQFVTMTHLLDFPHSNHVKSCFQNME
ICKRRVHMYDTVSQIKSPFTTHVAPSTSTNLTMSFSNQLSTVHNQASVLASSSTAAAATL
SLANSDVSLLNYQSALYPPSAAPVPGVAQQGVSLQPGTTQICTQTDPFQQTFIVCPPAFQ
TGLQATTKHSGFPVRMDNAVPLVPQAPAAQPLQIQSGVLTQGSCTPLMVATLHPQVATIT
PQYAVPFTLSCAAGRPALVEQTAAVLQAWPGGTQQILLPSAWQQLPGVALHNSVQPTAVI
PEAMGSSQQLADWRNAHSHGNQYSTIMQQPSLLTNHVTLATAQPLNVGVAHVVRQQQSSS
LPSRKNKQSAPVSSTSSLEVLPSQVYSLVGSSPLRTTSSYNSLVPVQDQHQPIIIPDTPS
PPVSVITIRSDTDEEEDNKFKPSSSSLKARSNVISYVTVNDSPDSDSSLSSPYPTDTLSA
LRGNSGTLLEGPGRTAADGIGTRTIIVPPLKTQLGDCTGATQASGLLSSSKTKPVASVSG
QSSGCCITPTGYRAQRGGASAVQPLNLSQNQQSSSASTSQERSSNPAPRRQQAFVAPLSQ
APYAFQHGSPLHSTGHPHLAPAPAHLPSQPHLYTYAAPTSAAALGSTSSIAHLFSPQGSS
RHAAAYTTHPSTLVHQVPVSVGPSLLTSASVAPAQYQHQFATQSYIGSSRGSTIYTGYPL
SPTKISQYSYL
NT seq 3636 nt   +upstreamnt  +downstreamnt
atggcatcacagctgcaggtgttttcccctccatcagtgtcgtcgagtgccttctgcagt
gcgaagaaactgaaaatagagccctctggctgggatgtttcaggacagagcagcaacgac
aaatattatacccacagcaaaaccctcccagctacacaagggcaagccagctcctctcac
caggtagcaaatttcaatattcctgcttacgaccagggcctcctcctccaggctcctgca
gtggagcatattgtggtaacagctgctgacagctcaggcagtgccgccacggcaaccttc
caaagcagccagaccctgactcacaggagcaacgtttctttgcttgagccatatcaaaaa
tgtggattgaaaagaaaaagtgaggaagtcgacagcaacggtagcgtgcagatcatagaa
gaacatccccctctcatgctgcaaaacagaactgtggtgggtgctgctgccacgaccacc
actgtgaccacgaagagtagcagttctagcggagaaggggattaccagctggtccagcat
gagatcctgtgctctatgaccaatagttatgaagtcttggagttcctaggccgagggaca
tttggacaggtggcaaagtgctggaagcggagcaccaaggaaattgtggccattaagatc
ttgaagaaccacccctcctatgccagacaaggacagatcgaagtgagcatcctttctcgc
ctaagcagtgagaatgctgatgagtataattttgtccgatcttatgagtgttttcagcac
aagaatcatacctgccttgtgtttgagatgttggagcagaatttgtatgattttctaaag
cagaacaagtttagcccactgccactcaagtacataagaccaatcttgcagcaggtggcc
acagccctgatgaagctgaagagtcttggtctgattcatgctgacctcaaacctgagaac
atcatgctggttgatccagttcgccaaccctaccgagtgaaggtcattgactttggttct
gcgagtcatgtttccaaagccgtatgttcaacctacctgcaatcacgctactacagagct
cctgaaattatccttgggttgccattctgtgaggctattgacatgtggtcgctgggctgt
gtaatagctgagctgttcctgggctggcctctttatcctggtgcttcagaatacgatcag
attcgttatatctcacaaacacaaggcctgccagctgaatatctcctcagtgccggaaca
aaaacaactaggtttttcaacagagatcctaatttggggtacccactgtggaggcttaag
acaccagaagaacatgaattagagactggaataaagtcaaaagaagctcggaagtacatt
tttaactgtttagatgacatggctcaggtaaatatgtctacagacttagagggaacagac
atgttggcagaaaaggcagaccggagagaatacattgatctcctaaagaaaatgctgacg
attgatgcagacaagagagtcacgcctctgaaaactcttaaccaccagttcgtgacaatg
acccaccttctggactttccacacagtaaccatgttaagtcttgtttccagaacatggag
atctgcaagcggagggttcacatgtatgacacagtgagtcagatcaagagtcccttcact
acccatgtggctccaagtacaagcacaaatctaaccatgagcttcagcaaccagctcagc
acagtgcacaaccaggccagtgttttagcctccagctctactgcagcagctgctactctt
tctctggctaactcagacgtctcgctgctaaactaccagtcagctttgtaccctccgtcc
gcagcgcccgttcctggagttgcccagcagggtgtttccttacagcctggaaccacccag
atctgcacccagacggacccattccagcaaacattcatagtgtgtccacctgcctttcag
actgggctacaagcaacaacaaagcattctggattccctgtgaggatggataatgctgtg
ccacttgtcccccaggcgcccgcagcccagccactgcagatacagtcaggagtgctcaca
cagggaagctgtacaccactaatggtagcaactctccaccctcaagtagccaccatcaca
ccgcagtatgcggtgccctttaccctgagctgcgcagccggccggccggcgctggttgaa
cagactgctgctgtactgcaagcttggcctggaggaacccaacagattctcctgccttca
gcatggcagcagctgcctggggtcgctctacacaactctgtccagcctactgcagtgatt
ccagaggccatggggagcagccagcagctagccgactggaggaatgcccactctcatggc
aaccagtacagcactatcatgcaacagccatctttgctgactaaccatgtgacgttggcc
actgcgcagcctctgaatgttggtgttgctcatgttgtcagacaacagcagtctagttcc
ctcccttcaaggaagaataaacagtctgctccagtctcatccacatcttctctggaagtt
ctgccttcccaagtttattctctggttggaagtagtcctcttcgtaccacatcttcttat
aattccctagtccctgtccaagaccagcatcagccaatcatcattccagacactcccagc
cctcctgtgagtgtcatcactatccgtagtgacaccgatgaagaagaggacaacaaattc
aagcccagcagctcgagcctgaaggcgaggtctaatgtcatcagttatgtgactgtcaat
gattctccagactctgactcctccctgagcagcccataccccacagacactctgagtgct
ctgcggggcaacagcgggacacttctggagggacctggcagaactgcagcagatggcatt
ggcacccgtacgatcattgtgcctcctttaaaaacacagcttggcgactgtactggagca
acacaggcctcaggtctccttagcagtagtaagaccaagccagtggcctcagtgagtggg
cagtcatctggatgctgtatcactcccacagggtaccgagctcaacgagggggagccagc
gcggtgcagccactcaaccttagccagaaccagcagtcatcgtcagcttcaacctcgcag
gaaagaagcagcaaccctgctccccgcagacagcaggcatttgtggccccgctctcccaa
gccccctacgccttccagcatggcagcccactgcactcgacggggcacccacatttggcc
ccagcccctgctcacctgccaagccagcctcacctgtatacgtacgctgcccccacttct
gctgctgcattgggttccaccagttccattgctcatcttttctccccccagggttcctca
aggcatgctgcagcttataccacccaccccagcactctggtgcatcaggttcctgtcagt
gttgggcctagcctcctcacctctgccagtgtggcccctgctcagtaccaacaccagttt
gccactcagtcctatattgggtcttcccgaggctcaacaatttacactggatacccgctg
agtcctaccaagatcagtcagtattcttatttgtag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (11)   
   UniProt (1)   
   RefSeq(pep) (10)   
DNA sequence (18)   
   RefSeq(nuc) (12)   
   GenBank (3)   
   EMBL (3)   
Protein domain (8)   
   Pfam (8)   
All databases (49)   

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KEGG   Rattus norvegicus (rat): 83617
Entry
83617             CDS       T01003                                 

Gene name
Hipk3
Definition
(RefSeq) homeodomain-interacting protein kinase 3
  KO
K08826  homeodomain interacting protein kinase [EC:2.7.11.1]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04218  Cellular senescence
Brite
KEGG Orthology (KO) [BR:rno00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    83617 (Hipk3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rno01001]
    83617 (Hipk3)
Enzymes [BR:rno01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     83617 (Hipk3)
Protein kinases [BR:rno01001]
 Serine/threonine kinases: CMGC group
  DYRK family [OT]
   83617 (Hipk3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo Pkinase_fungal TCAD9 APH RIO1
Other DBs
NCBI-GeneID: 83617
NCBI-ProteinID: NP_113975
RGD: 619884
Ensembl: ENSRNOG00000011358
UniProt: O88850
Position
3
AA seq 1191 aa
MASQVLVYPPYVYQTQSSAFCSVKKLKVEPSGCVFQERACPQIHVNGRHFGNPLPSTKGS
AFQTKIPFSKPRGHSFSLQAGAIVVKDTAGATKVIAAQAQQAGVEAPRAVVWRNRLHFLG
GPQRCGLKRKSEELDNHSGAMQIVDELSILPAMLQTNMGNPVTVVTATTGSKQNCTSGEG
DYQLVQHEVLCSVKNTYEVLDFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQI
EVSILARLSTENADEYNFVRAYECFQHRNHTCLVFEMLEQNLYDFLKQNKFSPLPLKVIR
PVLQQVATALKKLKSLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKTVCSTYL
QSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGALEYDQIRYISQTQGLPGE
QLLNVGTKSTRFFCRETDMSHSGWRLKTLEEHEAETGMKSKEARKYIFNSLDDIVHVNTV
MDLEGSDLLAEKADRREFVSLLKKMLLIDADLRITPIETLNHPFVSMKHLLDFPHSSHVK
SCFHIMDICKSPSSCETNNHSKMSLLRPVASNGTAALAANFTKVGTLRSQALTTSAHSVV
HHGIPLQAGTAQFGCGDAFHQTLIICPPAIQGIPAAHGKPTSYSIRVDNTVPLVTQAPAV
QPLQIRPGVLSQTWSGRTQQMLIPAWQQVTPMAPAAATLTSEGMAGSQRLGDWGKMIPHS
NHYNSVMPPPLLTNQITLSAPQPISVGIAHVVWPQPATTKKNKLCQNRSNSLQNTNVPHS
AFISPKIISGKEVEEVSCVETQDNHTSEGEARTCHEASVRQDSSVSDKQRQTIIIADSPS
PAVSVITISSDTDDEETSPRPSLRECKGSLDCEACQSTLNIDRMCSLSSPDSTLSTSSSG
QSSPSPCKRPNSMSDDEQESGCETVDGSPTSDSSGHDSPFAESSFVEDTPQNPELGTCAG
TEAKPALSTAVEPPVGTERGLNVDAHMANTDSTCQPLTKGQPAPGKLNQPSASAARQQKP
TSAFQQQHLNLSQVQHFGTGHQEWNGNFGHRRQQAYIPTSVTSNPFTLSHGSPNHTAVHA
HLAGSAHLGGQPTLLPYPPSTALSSAAPVAHLLASPCTSRPMLQHPTYNISHPSGIVHQV
PVGINPRLLPSPTIHQTQYKPIFPPHSYIAASPAYTGFPLSPTKLSQYPYM
NT seq 3576 nt   +upstreamnt  +downstreamnt
atggcctcacaagtcttggtctacccaccatatgtttatcaaactcagtcaagtgccttt
tgtagtgtgaagaaactgaaagtagagcccagcggttgtgttttccaggaaagagcctgc
cctcagatccatgtgaatggtagacactttggaaatcctcttccttccacgaagggtagt
gctttccagacaaagataccattctctaaacctcgaggacacagcttttcactgcaggca
ggggccattgttgtcaaagacactgccggtgctacaaaggtcatagcagctcaggcgcag
caggctggagtggaggcacctcgggccgtggtgtggagaaacaggctacatttcctagga
ggtccccagcgatgcgggttaaagcgcaagagtgaggagttggataatcacagcggcgcg
atgcagattgtcgatgaactgtccatacttcctgcaatgttgcaaaccaacatgggaaac
ccagtgacagttgtgacagcgaccacaggatcgaaacagaactgtaccagtggggaaggt
gactatcagttagtgcagcacgaagtcttgtgctctgtgaaaaacacatatgaagtcctg
gattttcttggtcgtggcactttcggccaggttgttaaatgctggaagagagggacaaat
gaaattgtagccattaaaattttgaagaatcacccttcgtatgcacgtcaagggcagata
gaagtgagcatcttagcaaggctcagtactgagaacgctgatgagtataactttgtgcga
gcctatgagtgcttccagcaccgcaaccatacctgcctggtctttgagatgctggagcag
aacctgtatgacttcctgaaacagaataaattcagtcccttgcccctaaaggtgatccgg
cccgttcttcagcaagtggccactgcactgaagaaattaaaaagtcttggtttaattcat
gctgaccttaaaccagagaatattatgttggtggatcctgttcgacagccatacagggtt
aaagtgatagactttggatcggccagtcatgtatcaaagactgtttgctcaacgtatcta
caatctcggtactatagagctccagagattatattggggttgccgttttgtgaagccata
gacatgtggtcactgggatgcgtgattgcagagttattccttggatggccactctacccg
ggagccttggagtatgaccagattcgatacatttctcagactcaaggtttaccaggagaa
caattgttgaatgtgggtacaaaatccacaagatttttttgcagagaaacagatatgtct
cattctggttggaggttaaagacactggaagagcatgaagcagagacaggaatgaagtct
aaagaggccagaaagtacatattcaacagtctggacgatatagtgcatgtgaacacagtg
atggacttggaaggaagtgatctcttggctgagaaagctgatagaagagaatttgttagt
ctgttgaagaaaatgttgctgattgatgcagatttaagaattactccgatcgagactctg
aaccacccattcgttagtatgaagcacctactagattttcctcacagcagccatgtaaag
tcctgttttcatatcatggatatttgtaagtctccgagttcatgtgaaacaaacaaccac
agtaaaatgtcactcttacgaccagttgcatccaatggcactgctgctctagcggcaaac
tttactaaagtcggaacattaagaagtcaggcgttgaccacatctgctcactcggtcgtg
caccatggtatacctctgcaggcggggaccgcacagttcggttgtggtgatgcttttcat
cagaccctgattatctgtcccccagctattcaaggtattcccgcagcacatggtaagccc
accagttattccataagggtggacaacacagttccgcttgtgactcaggccccagctgta
cagcctctgcagatccgaccaggagtcctttcacagacatggtctggtcgaacacagcag
atgctaatacctgcctggcagcaggtaacacccatggctcctgctgctgcaacactaact
tctgaaggcatggctggttcacagaggcttggagactgggggaaaatgattccacacagc
aatcattataactccgtgatgccgccacctcttctgaccaaccagataacattgtcggcc
cctcagcctatcagcgtaggcatcgcacatgttgtctggcctcagcctgccactaccaag
aaaaataagctgtgccagaacaggagtaattcattgcagaacaccaatgtcccacattca
gcatttatttctccaaagataatcagtgggaaagaagttgaggaagtaagttgtgtagaa
acacaggacaatcatacctcagaaggagaggcaagaacttgccatgaagcgtctgtcaga
caggattcttcagtttcagacaaacagcggcaaaccatcatcattgccgactccccaagt
cctgccgtgagtgtgatcaccattagcagtgacactgatgacgaagagacctcacccaga
ccttcactccgagagtgtaaaggtagtctggattgtgaagcttgccaaagcactttgaat
attgatcggatgtgttcactcagcagtcccgacagcactctgagtaccagctcctcaggg
cagtccagcccatccccttgcaaaagaccgaacagtatgtcagatgatgaacaggaaagt
gggtgtgagactgtggacggctctccaacgtcagactcctcggggcatgacagtccattt
gcagagagcagttttgtggaagacactcctcaaaacccagagctggggacttgtgctggc
acagaggccaagccagctcttagcactgctgtggagccaccagtggggacagagcgtggc
ctgaacgtcgatgcgcacatggccaacacagattctacatgccagccattgacaaaaggc
cagcccgcccctggaaagctgaaccagccctctgcctcggctgctcgtcagcaaaagccc
acatcagcattccagcagcagcatttgaacctgagccaggttcagcatttcggaactggg
catcaagaatggaatggaaactttgggcatcgaagacagcaagcatatattcctactagt
gttaccagtaatccattcactctttctcacggaagtcccaaccacacagcagtgcatgcc
catctggctggaagtgcgcacctcggaggacagcccactctgcttccgtacccgccatca
actgccctcagtagtgctgcacccgtggcccacctcctagcctctccgtgtacctcaaga
cctatgttacagcatccaacttataatatctcccatcccagtggcatagttcaccaagtc
cccgtgggcataaatccccgcctgttaccatccccgaccattcatcagactcagtacaaa
ccaatcttccctccacattcttacattgcagcatcgcctgcatatactggatttccattg
agtccaacaaaactcagccagtatccatatatgtga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (11)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (9)   
DNA sequence (13)   
   RefSeq(nuc) (9)   
   GenBank (2)   
   EMBL (2)   
Protein domain (7)   
   Pfam (7)   
All databases (43)   

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