KEGG   Rattus norvegicus (rat): 309295Help
Entry
309295            CDS       T01003                                 

Gene name
Ikbkg, Nemo
Definition
(RefSeq) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
  KO
K07210  inhibitor of nuclear factor kappa-B kinase subunit gamma
Organism
rno  Rattus norvegicus (rat)
Pathway
rno01523  Antifolate resistance
rno04010  MAPK signaling pathway
rno04014  Ras signaling pathway
rno04062  Chemokine signaling pathway
rno04064  NF-kappa B signaling pathway
rno04151  PI3K-Akt signaling pathway
rno04210  Apoptosis
rno04380  Osteoclast differentiation
rno04620  Toll-like receptor signaling pathway
rno04621  NOD-like receptor signaling pathway
rno04622  RIG-I-like receptor signaling pathway
rno04623  Cytosolic DNA-sensing pathway
rno04625  C-type lectin receptor signaling pathway
rno04657  IL-17 signaling pathway
rno04658  Th1 and Th2 cell differentiation
rno04659  Th17 cell differentiation
rno04660  T cell receptor signaling pathway
rno04662  B cell receptor signaling pathway
rno04668  TNF signaling pathway
rno04920  Adipocytokine signaling pathway
rno05132  Salmonella infection
rno05135  Yersinia infection
rno05142  Chagas disease (American trypanosomiasis)
rno05145  Toxoplasmosis
rno05160  Hepatitis C
rno05161  Hepatitis B
rno05162  Measles
rno05163  Human cytomegalovirus infection
rno05164  Influenza A
rno05165  Human papillomavirus infection
rno05166  Human T-cell leukemia virus 1 infection
rno05167  Kaposi sarcoma-associated herpesvirus infection
rno05168  Herpes simplex virus 1 infection
rno05169  Epstein-Barr virus infection
rno05170  Human immunodeficiency virus 1 infection
rno05200  Pathways in cancer
rno05203  Viral carcinogenesis
rno05212  Pancreatic cancer
rno05215  Prostate cancer
rno05220  Chronic myeloid leukemia
rno05221  Acute myeloid leukemia
rno05222  Small cell lung cancer
rno05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
rno05340  Primary immunodeficiency
rno05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    309295 (Ikbkg)
   04010 MAPK signaling pathway
    309295 (Ikbkg)
   04064 NF-kappa B signaling pathway
    309295 (Ikbkg)
   04668 TNF signaling pathway
    309295 (Ikbkg)
   04151 PI3K-Akt signaling pathway
    309295 (Ikbkg)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    309295 (Ikbkg)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    309295 (Ikbkg)
   04621 NOD-like receptor signaling pathway
    309295 (Ikbkg)
   04622 RIG-I-like receptor signaling pathway
    309295 (Ikbkg)
   04623 Cytosolic DNA-sensing pathway
    309295 (Ikbkg)
   04625 C-type lectin receptor signaling pathway
    309295 (Ikbkg)
   04660 T cell receptor signaling pathway
    309295 (Ikbkg)
   04658 Th1 and Th2 cell differentiation
    309295 (Ikbkg)
   04659 Th17 cell differentiation
    309295 (Ikbkg)
   04657 IL-17 signaling pathway
    309295 (Ikbkg)
   04662 B cell receptor signaling pathway
    309295 (Ikbkg)
   04062 Chemokine signaling pathway
    309295 (Ikbkg)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    309295 (Ikbkg)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    309295 (Ikbkg)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    309295 (Ikbkg)
   05203 Viral carcinogenesis
    309295 (Ikbkg)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    309295 (Ikbkg)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    309295 (Ikbkg)
   05221 Acute myeloid leukemia
    309295 (Ikbkg)
   05220 Chronic myeloid leukemia
    309295 (Ikbkg)
   05215 Prostate cancer
    309295 (Ikbkg)
   05222 Small cell lung cancer
    309295 (Ikbkg)
  09163 Immune disease
   05340 Primary immunodeficiency
    309295 (Ikbkg)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    309295 (Ikbkg)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    309295 (Ikbkg)
   05135 Yersinia infection
    309295 (Ikbkg)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    309295 (Ikbkg)
   05170 Human immunodeficiency virus 1 infection
    309295 (Ikbkg)
   05162 Measles
    309295 (Ikbkg)
   05164 Influenza A
    309295 (Ikbkg)
   05161 Hepatitis B
    309295 (Ikbkg)
   05160 Hepatitis C
    309295 (Ikbkg)
   05168 Herpes simplex virus 1 infection
    309295 (Ikbkg)
   05163 Human cytomegalovirus infection
    309295 (Ikbkg)
   05167 Kaposi sarcoma-associated herpesvirus infection
    309295 (Ikbkg)
   05169 Epstein-Barr virus infection
    309295 (Ikbkg)
   05165 Human papillomavirus infection
    309295 (Ikbkg)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    309295 (Ikbkg)
   05142 Chagas disease (American trypanosomiasis)
    309295 (Ikbkg)
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    309295 (Ikbkg)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rno01001]
    309295 (Ikbkg)
Protein kinases [BR:rno01001]
 Serine/threonine kinases: Other
  IKK family [OT]
   309295 (Ikbkg)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: NEMO CC2-LZ zf_C2H2_10 APG6_N zf_C2H2_ZHX ERM DpnI_C
Motif
Other DBs
NCBI-GeneID: 309295
NCBI-ProteinID: NP_954534
RGD: 735223
Ensembl: ENSRNOG00000060936
UniProt: Q6TMG5
Position
Xq37
AA seq 412 aa AA seqDB search
MSRHLWKNQLSEMVQPSGGPAEDQDMLGEESSLGKPAMLHLPSEQGTPETLQRCLEENQE
LRDAIRQSNQMLRERCEELLHFQVSQREEKEFLMCKFQEARKLVERLSLEKLDLRRQREQ
ALEDLEHLKKCQQQMAEDKASVKAQVTSLLGELQESQSRLEAATKERQTLEGRIRAVSEQ
VRQLESEREVLQQQHSVQVDQLRMQNQSVEAALRMERQAASEEKRKLAQLQAAYHQLFQD
YDSHIKSSKGMQLEDLRQQLQQAEEALVAKQELIDKLKEEAEQHKIVMETVPVLKAQADI
YKADFQAERHAREKLVERKELLQEQLEQLQREFNKLKVGCHESARIEDMRKRHVETSQPP
LLPAPAHHSFHLALSNQRRSPPEEPPDFCCPKCQYQAPDMDTLQIHVMECIE
NT seq 1239 nt NT seq  +upstreamnt  +downstreamnt
atgagcaggcacctctggaagaatcagttgagtgagatggtgcaacccagtggtggccca
gcagaggaccaggacatgctgggtgaagaatcttctctggggaagccagcaatgctacat
cttccttcagagcagggtactcctgagaccctccagcgctgtctggaagagaatcaagaa
ctccgagatgctatccggcagagcaatcagatgctgagggaacgctgtgaggagctgctg
catttccaggtcagccagcgggaggagaaggagttcctcatgtgcaaattccaggaagcc
aggaagctggtggagagactgagcttggagaagcttgacctgcggaggcagagagaacag
gccttagaggatttggagcatctgaagaaatgccaacagcagatggctgaggacaaggcc
tctgtgaaagctcaggtgacatcattgctgggggaactccaggagagccagagtcgtttg
gaggctgctaccaaggaacgacaaactttagagggaaggattcgagcagttagtgagcag
gtcagacagctggagagtgagcgggaggtgctgcagcagcagcacagtgtccaggtggac
caactgcgcatgcagaaccagagtgtggaggctgccttgcgaatggagcgacaggctgct
tcagaggagaagcggaagctggctcagttgcaggcagcctatcaccaactcttccaagac
tatgacagccacattaagagcagcaagggcatgcagctggaagatctgaggcagcagctc
cagcaagctgaggaggccctggtagccaaacaggaattgattgataagctgaaagaggaa
gctgagcagcacaagattgtcatggagaccgttccagtcttgaaagcccaggcggacatc
tacaaggctgacttccaagctgagaggcatgcccgggagaaactggtggagaggaaggag
cttttgcaggagcagttggagcagctgcagcgcgagttcaacaagttgaaagttggctgc
catgagtcagccaggattgaggatatgaggaagcggcatgtagagacttcccagccccct
ttactccctgctccagctcaccactcctttcatttggccttgtccaaccagcggaggagc
cctcctgaggaaccacctgacttctgttgtcccaagtgccagtatcaggctcctgatatg
gacactctacagatacatgtcatggagtgcatagagtag

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