KEGG   Rattus norvegicus (rat): 311450Help
Entry
311450            CDS       T01003                                 

Gene name
Pak7, PAK-5, PAK-7, Pak5
Definition
(RefSeq) p21 (RAC1) activated kinase 7
  KO
K05736  p21-activated kinase 5 [EC:2.7.11.1]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04012  ErbB signaling pathway
rno04014  Ras signaling pathway
rno04360  Axon guidance
rno04510  Focal adhesion
rno04660  T cell receptor signaling pathway
rno04810  Regulation of actin cytoskeleton
rno05170  Human immunodeficiency virus 1 infection
rno05211  Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    311450 (Pak7)
   04012 ErbB signaling pathway
    311450 (Pak7)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    311450 (Pak7)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    311450 (Pak7)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    311450 (Pak7)
  09158 Development and regeneration
   04360 Axon guidance
    311450 (Pak7)
 09160 Human Diseases
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    311450 (Pak7)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    311450 (Pak7)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rno01001]
    311450 (Pak7)
Enzymes [BR:rno01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     311450 (Pak7)
Protein kinases [BR:rno01001]
 Serine/threonine kinases: STE group
  STE20 family
   311450 (Pak7)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Pkinase Pkinase_Tyr PBD Kinase-like Pkinase_fungal
Motif
Other DBs
NCBI-GeneID: 311450
NCBI-ProteinID: NP_001101251
RGD: 1312009
Ensembl: ENSRNOG00000005509
UniProt: D4A280
Position
3q36
AA seq 718 aa AA seqDB search
MFGKKKKKIEISGPSNFEHRVHTGFDPQEQKFTGLPQQWHSLLADTANRPKPMVDPSCIT
PIQLAPMKTIVRGNKSCKESSINGLLEDFDNISVTRSNSLRKESPPTPDQGAASRIQGHS
EENGFITFSQYSSESDTTTDYTTEKYRDRSLYGDDLDLYYRGSHAAKQNGHAMKMKHGDA
YYPEMKPLKSDLARFPVDYHTHLDSLSKASEYGDLKWDYQRASSSSPLDYSFQLTPSRTA
GTSRCSKESLAYSESDWGPSFDDYDRRPKSSYLHQTSPQPAMRQRSKSGSGLQEPMMPFG
ASAFKTHPQGHSYNSYTYPRLSEPTMCIPKVDYDRAQMVFSPPLSGSDTYPRGPTKLPQS
QSKVGYSSSSHQYPGYHKASLYHHPSLQTSSQYISTASYLSSLSISSSTYPPPSWGSSSD
QQPSRVSHEQFRAALQLVVSPGDPREYLDNFIKIGEGSTGIVCIATEKHTGKQVAVKKMD
LRKQQRRELLFNEVVIMRDYHHDNVVDMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMN
EEQIATVCLSVLKALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKRK
SLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMIDGEPPYFNEPPLQAMRRIRDSLPP
RVKDLHKVSSMLRGFLDLMLVREPSQRATAQELLGHPFLKLAGPPSCIVPLMRQYRHH
NT seq 2157 nt NT seq  +upstreamnt  +downstreamnt
atgtttgggaagaaaaagaaaaagatcgaaatatccggcccatctaactttgaacacagg
gttcatactgggtttgatccacaagagcagaagtttactggccttccccagcagtggcac
agcctgttagcagacacagccaacaggcccaagcctatggtggatccatcatgcatcaca
cccatacaactggctcccatgaagacaatcgtcagaggaaataaatcctgcaaggaaagc
tctatcaacggtctgctagaggatttcgacaacatctccgtgactcgctccaactcccta
aggaaagaaagcccacccaccccagatcagggagcagctagccgcattcaaggccactcc
gaagaaaacggcttcattactttctcacaatattctagtgaatctgatactactacggac
tacacaactgaaaagtatagagacaggagtctctatggagacgacctggatctgtactat
agaggcagccatgcagccaagcaaaacgggcatgctatgaagatgaaacatggagatgcc
tactatcctgagatgaagcctttgaaatccgacctggccagattccctgtcgactatcac
acacacttggactcgctgagcaaagcaagtgagtacggtgacctcaagtgggattatcag
cgagcctccagtagctcccctctggactactcattccagctcacgccttccagaactgca
gggaccagcaggtgctccaaggagagtctggcatacagtgaaagtgattggggacccagc
tttgatgactatgataggaggccaaaatcatcctacctgcatcagacaagccctcagcca
gccatgcgccagagatccaagtcaggctcagggcttcaggaacccatgatgccatttgga
gcaagtgcatttaaaactcatcctcaaggacactcgtacaactcctacacctaccctcga
ttgtctgagcccacaatgtgcattccaaaggtggattatgatcgagcacagatggtcttc
agtcctccactgtcagggtccgacacctatcccagaggccccaccaaactacctcaaagt
caaagcaaagtgggctactcttcaagtagccaccagtatcctgggtaccacaaagcatcc
ctataccatcatccgtccctgcaaaccagttctcagtacatctccaccgcttcttacttg
agctctctcagtatctcctcgagcacctaccctccacccagctggggctcctcttcagac
cagcagccctctagggtatcccatgaacagtttcgagctgccctgcaactggtggtcagc
ccaggagaccccagggaatatttggataactttattaaaatcggagaagggtcgacaggc
atcgtgtgcattgcaacagagaagcacacaggcaagcaagtggcggtgaagaaaatggac
ctccgaaagcaacagagacgggaactcctttttaatgaggtcgtgataatgcgtgattac
caccatgacaatgtagttgacatgtataacagctaccttgttggagatgagctctgggtg
gtcatggagtttctagaaggtggtgccttgacagacatcgtcactcataccagaatgaat
gaagaacagatagctactgtctgcctgtcagttctgaaagcgctgtcctaccttcataac
caaggagtgattcacagggacataaagagtgactccattcttctgacaagcgatggccgg
ataaagttatctgactttggcttctgtgctcaagtttccaaagaggtgccaaagaggaag
tcactggtgggtaccccatactggatggctcctgaggtgatttccaggctaccttatggg
acagaggtggacatctggtccctcgggataatggtgatagagatgattgatggtgagcct
ccctatttcaatgagcctcctctgcaggccatgaggaggatccgggacagtttacctcca
agagtgaaggacctgcacaaggtttcttccatgctccgaggattcctagatcttatgttg
gtgagggagccctctcaaagagccacagctcaagaacttcttggacatccattcttaaaa
ttggcaggcccgccatcttgcatcgttcccctcatgagacaatataggcatcactga

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