KEGG   Rattus norvegicus (rat): 311658
Entry
311658            CDS       T01003                                 

Gene name
Nfatc2
Definition
(RefSeq) nuclear factor of activated T-cells, cytoplasmic 2
  KO
K17332  nuclear factor of activated T-cells, cytoplasmic 2
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04022  cGMP-PKG signaling pathway
rno04218  Cellular senescence
rno04310  Wnt signaling pathway
rno04360  Axon guidance
rno04370  VEGF signaling pathway
rno04380  Osteoclast differentiation
rno04625  C-type lectin receptor signaling pathway
rno04650  Natural killer cell mediated cytotoxicity
rno04658  Th1 and Th2 cell differentiation
rno04659  Th17 cell differentiation
rno04660  T cell receptor signaling pathway
rno04662  B cell receptor signaling pathway
rno04921  Oxytocin signaling pathway
rno05135  Yersinia infection
rno05161  Hepatitis B
rno05163  Human cytomegalovirus infection
rno05166  Human T-cell leukemia virus 1 infection
rno05167  Kaposi sarcoma-associated herpesvirus infection
rno05170  Human immunodeficiency virus 1 infection
rno05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
rno05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    311658 (Nfatc2)
   04370 VEGF signaling pathway
    311658 (Nfatc2)
   04022 cGMP-PKG signaling pathway
    311658 (Nfatc2)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    311658 (Nfatc2)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    311658 (Nfatc2)
   04650 Natural killer cell mediated cytotoxicity
    311658 (Nfatc2)
   04660 T cell receptor signaling pathway
    311658 (Nfatc2)
   04658 Th1 and Th2 cell differentiation
    311658 (Nfatc2)
   04659 Th17 cell differentiation
    311658 (Nfatc2)
   04662 B cell receptor signaling pathway
    311658 (Nfatc2)
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    311658 (Nfatc2)
  09158 Development and regeneration
   04360 Axon guidance
    311658 (Nfatc2)
   04380 Osteoclast differentiation
    311658 (Nfatc2)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    311658 (Nfatc2)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    311658 (Nfatc2)
   05170 Human immunodeficiency virus 1 infection
    311658 (Nfatc2)
   05161 Hepatitis B
    311658 (Nfatc2)
   05163 Human cytomegalovirus infection
    311658 (Nfatc2)
   05167 Kaposi sarcoma-associated herpesvirus infection
    311658 (Nfatc2)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    311658 (Nfatc2)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    311658 (Nfatc2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:rno03000]
    311658 (Nfatc2)
Transcription factors [BR:rno03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   RHR (Rel homology region) NF-AT
    311658 (Nfatc2)
SSDB
Motif
Pfam: RHD_dimer RHD_DNA_bind TIG
Other DBs
NCBI-GeneID: 311658
NCBI-ProteinID: NP_001101275
RGD: 1307690
Ensembl: ENSRNOG00000012175
UniProt: D4A0I8
Position
3
AA seq 931 aa
MDAPEPQSDPDGGDGPGHEPGGSSQDELDFSILFDYDYLNPIEEEPIAHKAISSPSGLAY
PDDVLDYGLKPCNPLASLSGEPPGRFGESDSIGFQNFLSPAKPAGASGPSPRIEITPSHE
LMQAGGALRGRDAGLSPEQPALALAGMAASPRFTLPVPGFEGYREPLCLSPASSGSSASF
ISDTFSPYTSPCVSPNNAGPDDLCPQFQNIPAHYSPRTSPIMSPRTSLAEDSCLGRHSPV
PRPASRSSSPGAKRRHSCAEALVAPLPAASPQRSRSPSPQPSPHVAPQDDGIPAGYPPTA
GSAVLMDALNSLATDSPCGIPSKIWKTSPDPTPVSTAPSKAGLARHIYPAVEFLGPCEQE
ERRNSAPESILLVPPTWPKQLVPAIPICSIPVTASLPPLEWPLSNQSGSYELRIEVQPKP
HHRAHYETEGSRGAVKAPTGGHPVVQLHGYMENKPLGLQIFIGTADERILKPHAFYQVHR
ITGKTVTTTSYEKIVGNTKVLEIPLEPKNNMRATIDCAGILKLRNADIELRKGETDIGRK
NTRVRLVFRVHIPEPSGRIVSLQAASNPIECSQRSAHELPMVERQDMDSCLVYGGQQMIL
TGQNFTAESKVVFMEKTTDGQQIWEMEATVDKDKSQPNMLFVEIPEYRNKHIRVPVKVNF
YVINGKRKRSQPQHFTYHPVPAIKTEPSDEYEPSLICSPAHGGLGSQPYYPQHPMLAESP
SCLVATMAPCQQFRSGLSSPDARYQQQSPAAALYQRSKSLSPGLLGYQQPSLLAAPLGLA
DAHRSVLVHAGSQGQGQGQGSTLPHTSSASQQASPVIHYSPTNQQLRGGGHQEFQHIMYC
ENFGPSSVRPGLPPVNQGQRLSPGSYPTVIQQQTAPSQRAAKNGPPVSDQKEALPSGVTV
KQEQNLDQTYLDDVNEIIRKEFSGPPSRNQT
NT seq 2796 nt   +upstreamnt  +downstreamnt
atggacgccccggagccgcagtccgaccccgacggcggggacggccccggccacgagccc
gggggcagttcccaagacgagctggacttttccatcctcttcgattatgactatctgaac
cctatcgaagaagaaccgatcgcacataaggccatcagctcaccctccggactcgcatac
ccggatgatgtcctggactatggcctcaagccatgcaaccctctcgccagtctctctggc
gagccccctggccggttcggagagtcggatagtatagggttccagaactttctgagcccg
gccaagccagcaggggcttcgggcccgagccctcggatcgagatcactccatcccacgaa
ctgatgcaggcagggggggccctccgtgggagagatgccggcctgtcccccgagcagccg
gccctggctctggccggcatggccgccagcccgaggttcacactgcccgtgcccggcttc
gagggctaccgcgagccgctttgcttgagccccgctagcagcggctcctctgccagcttc
atttctgacaccttctccccctacacctcgccctgcgtctcacccaataacgccgggccc
gacgacctgtgtccccagtttcaaaacatccctgctcattattcccccagaacctctcca
ataatgtcacctcgaaccagcctcgccgaggacagctgcctgggccgacactcgcccgtg
ccccgtccggcatcccgctcctcctcacccggtgccaagcggaggcattcgtgcgcagag
gccttggttgcccctctgcccgcagcctcaccccagcgctcccggagcccctcgccacag
ccctcgcctcacgtggcaccccaggacgacggcatccccgctgggtacccccccacggcc
ggctctgctgttctcatggatgccctcaacagcctggccaccgactcgccctgcgggatc
ccctctaagatatggaagaccagtcctgatccaactcccgtgtccactgctccatccaag
gcaggcctggcccgccacatctaccctgctgtggagttcctggggccgtgtgagcaggag
gagaggaggaattccgctccagagtccatcctgctggtaccacccacctggcccaagcaa
ttggtgccggccattcccatctgcagcatccccgtgactgcatccctcccaccactagag
tggccactctccaaccagtcgggctcctatgagcttcggattgaggtccagcccaagccc
catcaccgagcccactatgagacagagggcagccgtggcgctgtcaaagccccaacagga
ggacaccctgtggtgcagctccacggctacatggagaacaagcctctggggcttcagatc
ttcatcgggacggctgatgaacggatccttaagccacacgccttctaccaagtacacagg
atcactgggaaaacagtgacaaccactagctatgagaagattgtgggcaacaccaaggtc
ctggagatccccctggagccaaagaacaacatgcgggccaccatcgactgcgcaggcatc
ctgaagctccgaaacgctgacatcgagctgcggaagggtgagacagacataggcagaaag
aacacgcgtgtgcgccttgtgttccgtgtgcacatcccggagcccagtggacgcatcgtc
tccctgcaggctgcatccaaccccatcgagtgctctcagcgctctgcccacgagctgccc
atggtggagagacaagacatggacagctgcctggtctacggcggccagcagatgatcctc
acgggccagaacttcacagctgagtccaaggttgtgttcatggagaagactacagatggg
cagcagatttgggagatggaagctacagtggataaagacaagagccagcctaacatgctt
tttgttgagatccccgagtatcggaacaagcacatccgggtgcccgtgaaagtgaacttc
tacgtcatcaacggaaagagaaaacgaagtcagccacagcactttacttaccacccagtc
cccgccatcaagacagagcccagcgatgagtatgaaccgtctttgatctgcagccccgcc
cacggaggcctggggagccagccatattacccacagcacccaatgctggccgagtccccc
tcctgtcttgtggccaccatggccccttgccaacagttccgctcagggctctcatcccct
gatgctcgctaccagcagcagagccccgcagccgccctctaccagaggagcaagagcctg
agtccaggcctgctgggctaccagcagccgtccctcttggcagcacccttgggtctggct
gatgcccaccgttctgtgctggtgcatgctggttcgcaggggcaggggcaggggcagggc
tccaccttgccacacacctcctcggccagccagcaggcctcacccgtgatccactactca
cccaccaaccagcagcttcgtggtgggggtcaccaggagttccagcatatcatgtactgt
gagaacttcggccccagctctgtcaggcctggcctgcctcccgtcaaccaaggtcagagg
ctgagcccagggtcctaccccacggtcatccaacaacagactgccccgagccaaagagct
gccaaaaacggacccccggtcagtgaccagaaggaagccctgcccagtggagtgacagtc
aaacaggagcagaacctggaccagacttacctggatgacgttaatgaaatcatcaggaag
gagttttcgggacctccctcccgaaatcagacctag

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