KEGG   Rattus norvegicus (rat): 317420
Entry
317420            CDS       T01003                                 
Symbol
Wnk3
Name
(RefSeq) serine/threonine-protein kinase WNK3 isoform 1
  KO
K08867  WNK lysine deficient protein kinase [EC:2.7.11.1]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04928  Parathyroid hormone synthesis, secretion and action
Brite
KEGG Orthology (KO) [BR:rno00001]
 09150 Organismal Systems
  09152 Endocrine system
   04928 Parathyroid hormone synthesis, secretion and action
    317420 (Wnk3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rno01001]
    317420 (Wnk3)
   01009 Protein phosphatases and associated proteins [BR:rno01009]
    317420 (Wnk3)
Enzymes [BR:rno01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     317420 (Wnk3)
Protein kinases [BR:rno01001]
 Serine/threonine kinases: Other
  Wnk family
   317420 (Wnk3)
Protein phosphatases and associated proteins [BR:rno01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     317420 (Wnk3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr OSR1_C CCTL2_WNK
Other DBs
NCBI-GeneID: 317420
NCBI-ProteinID: NP_001398747
RGD: 1563131
Ensembl: ENSRNOG00000002537
UniProt: A0A1W2Q671
Position
X:23599278..23742290
AA seq 1745 aa
MATDSGEPASTEDSEKPDGVSFQSRVARAVAPLTVEARIKEKYSTFSASGETIERKRFFR
KSVEMTEDDKVAQSSRRDERKVATNISRVEKVPTNVLRGGQEVKYEQCSKATSESSKDCF
KEKTEKEMEEEAEMKAVATSPSGRFLKFDIELGRGAFKTVYKGLDTETWVEVAWCELQDR
KLTKAEQQRFKEEAEMLKGLQHPNIVRFYDSWESILKGKKCIVLVTELMTSGTLKTYLKR
FKVMKPKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLM
RTSFAKSVIGTPEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKV
TSGIKPASFNKVTDPEVKEIIEGCIRQNKSERLSIKDLLNHAFFAEDTGLRVELAEEDDC
SNSSLALRLWVEDPKKLKGKHKDNEAIEFSFNLEADTPEEVAYEMVKSGFFHESDSKAVA
KSIRDRVTLIKKIREKKPAGCLEERRDSQCKHARNVNPQQQTATLRPAPGPHNAAECEET
EVDQHVRQQLVQGKAQQQPSSVRGDTSSEPAAGPVLHSDTSSHPTVAYSSNQATSSQLQE
QPKLTRSPVLPVVQGQSSVMPIYAAGPAVASQSQISPLTIQKVSQIKPVSQPIGAEQQAT
PPNPDFVRSLNQDVTSVKENTNSPDTPSGNGKQDRIKQRRASCPRPEKGTKFQLTVLQVS
VSGDNMVECQLETHNNKMVTFKFDVDGDAPEDIADYMVEDNFVLENEKEKFVEELRAIVG
QAQEILHVHSAAEKSIGVDSVALESNSNQTGSSEQVLINSASTQTSNESAPQSSPVGRWR
FCINQTIKNREAQSPPSLQPSVAMVPGLHPFPNNTSNQEISQDTLFTVPGHHVVFTSKLD
GKIGERASVETEQTSVPYQAEDDKLKAPATDTSNYSATLVCPDPAGCEALTSQAGMFIPT
YPCQQAAVPADVLMSHPGESVQIGSNAVVTSVLVSSDQKPQSLSVQQPTIDAEFISQEGE
TTVNSETSSPKAVGATQTPGFEPTVLLPATILESDGERPPKMEFTDNRIKTLDEKLRNLL
YQEHSISTICPESQKDTQSIDSPFSSSAEDILSSPMPEVIAISHCGIQDSQAQSPNFQPT
GSKILSNVAASQPAHIPVLKRDLNVITSVPSELCLHEMSPDASLPGDPEAYPAAVSSDGT
IHLQTGGGYFGLSFTCPSLKNPISRKSWTRKLKSWAYRLRQSTSFFKRSKVRQVETEDKR
SAIASDPIPLTREFSADTRALSRCKAMSGSFQRGRFQVITVPQQQPVKMMSFGKEHRPPS
KKTTAQSNEQALTFTEAAVTQLIEVEPAIPTHKASVSSQKLRTLYETFKEDKGDPEQGDI
LSLSTARETSVSSVTTEKNVEETSTTGISVQSGSEMLDKEKDESTPGKQTCTNEFSATPA
GSGKSVAKAAPKSGQHLPARAQTQSSLFYSPSSPMSSDNESEIEDEDLKAELQRLREKHI
QEVVSLQTQQNKELQELYERLRATKDSKAQSSEVPMPPASPRRPRSFKSKLRSRPQSLTH
SDNLVVVKDVQRAESNTAPRQQSPASKKGMFTDDLHKLVDDWTRETVGNFPSKPSLNQLK
QSQQKSEAENWNKLHESTPSTVGYTSTWISSLSQIRGAAPSSLPHGLPLPSFPGPLASYG
MPHACQYNPVGAASYPVQWVGISGAAQQSVVLPTQSGGLFQPGMNLQSFPAPPVQNPPSI
PPGPK
NT seq 5238 nt   +upstreamnt  +downstreamnt
atggccactgattctggggagccagctagcacagaagattctgagaagcctgatggagtt
tcctttcaaagcagggttgcccgggctgttgcacctctgactgtagaagctagaataaag
gaaaaatacagtaccttttctgcttctggggaaaccattgaaagaaagagatttttccga
aagagtgttgagatgacagaagatgacaaagttgcccaatcttcccgcagagatgaaaga
aaagttgcaacaaatatttcaagagtagaaaaagttcctacaaatgtgctaagaggtggg
caagaagttaaatatgagcagtgttcaaaggcaacctcagaatcctcaaaagattgcttc
aaggagaaaactgaaaaggaaatggaagaagaagcagaaatgaaggctgtcgcaacgtcc
cctagtggcaggtttctaaaatttgatatagagctgggaagaggcgcttttaaaacagta
tataaaggattggacactgaaacatgggttgaagttgcttggtgtgagctacaggaccgc
aaattaactaaagctgagcagcaacggttcaaagaagaagctgagatgttgaaaggcctc
cagcatcccaatatagttcgattttacgattcatgggagtccatattgaaaggaaagaaa
tgtattgttttagtgactgaactaatgacatcaggaaccttaaagacgtacttaaaacga
tttaaagtcatgaaaccaaaggtcttaagaagctggtgcaggcaaattttaaaaggattg
cagttcttacacacaaggacgcctcctattattcaccgggatctgaaatgtgacaacatt
ttcatcacaggacccactggatctgtgaagattggtgatctgggacttgcaaccttaatg
cgcacatcctttgctaagagtgtcattggcactcctgagtttatggcgccagagatgtat
gaagaacactatgatgaatctgtagatgtttatgcttttgggatgtgtatgttggaaatg
gctacttcggagtatccatattctgagtgccagaatgcagcacaaatataccgtaaagta
accagtggcataaaaccagccagcttcaataaagtcacagaccctgaagtgaaagaaata
attgaaggatgtattagacaaaacaaatctgaaaggttatcgatcaaggatctactaaac
catgcattctttgctgaggatactggactgagggtggagttagcagaggaagatgattgc
tcaaattcatccttggctctaagactctgggttgaagatcctaagaaattaaaaggcaaa
cataaagacaatgaagctattgaattcagtttcaacttagaagcagatacacctgaggaa
gtagcgtatgaaatggtcaagtctggattcttccatgaaagtgattccaaagctgttgct
aagtccattagggaccgtgtgacactgattaaaaagataagggaaaagaagcctgctgga
tgcttagaggaacgcagggattcccagtgcaagcatgcgaggaatgtaaatcctcagcag
cagactgcaactttacgacctgctcctggtccacacaatgcggctgagtgtgaagaaaca
gaagttgatcaacatgttcgacagcagcttgtacaaggcaaagcacagcagcagccctcc
tctgttaggggtgacacttcatctgaaccagcagctggaccagttctacattcagatact
tcaagtcaccccactgtagcctattcttcaaaccaggcaactagttctcagttgcaggag
cagccaaagctgactcggtctccagttttgcctgtggttcaaggtcagtcttctgttatg
cccatatatgctgctggacctgcagttgcttcacagtcccagatttctccattaactatc
cagaaggtctcacagataaagcctgtatcccaaccaattggagctgaacaacaagcaact
cctccaaatccagattttgttcgaagcttgaatcaagatgtgacatctgtgaaagaaaac
accaatagccctgataccccaagtggaaatggcaaacaggatcggatcaaacaaagaaga
gcctcctgtccccgaccagagaaggggactaaattccagcttactgtccttcaggtctca
gtctctggggacaacatggtggaatgtcagctggaaacacataacaacaagatggtcaca
ttcaagtttgatgttgatggtgatgcacctgaggatatcgctgactatatggttgaagat
aactttgtgctggaaaatgagaaagaaaaatttgtagaggaattgagggctatcgtaggt
caagcccaggagatccttcatgtccactcagctgcagaaaaatctattggtgttgattct
gttgccttggaatctaacagtaaccaaacaggatcatctgaacaagtattgataaattct
gcatccactcaaactagcaatgaatctgctcctcagtcatccccagttggtcgctggcgg
ttttgtatcaaccaaacaataaaaaatcgtgaggcgcagtctcctccttcccttcagcct
tccgtggctatggtgcctgggttacatccatttcctaataacacaagtaatcaagaaata
tcacaggacacactgttcactgttccaggccatcatgtagttttcacctccaagttagat
ggtaagattggtgaacgtgctagtgtagaaacggagcagacgagtgttccctatcaagca
gaagatgacaaactaaaggcaccagctactgatacttccaattattctgctactttggtg
tgtccagatccagctggatgtgaggcactcaccagccaagcaggcatgttcatacctaca
tatccatgtcagcaagctgctgttccggctgatgtgcttatgtcccatcctggtgaatca
gttcagattggcagtaatgctgttgtaacgtcagtacttgtatcttctgatcaaaagcct
caatccttatcagtacagcagccaactatagatgcagagtttatttcacaagaaggagaa
accacagtaaactctgaaacgagttctcctaaggctgtcggtgccactcagactcctggc
tttgaaccaactgtgcttctacctgcgactatcctggaatcagatggggaacgacctcca
aaaatggagtttacagacaatcgaattaaaacactggatgaaaaattaagaaacctgctc
tatcaagagcacagcatttctaccatctgtcctgagagtcagaaggatactcaaagcata
gactctccattttcttcctctgctgaagatatactatcctccccaatgccagaagtcata
gccatcagtcactgtgggattcaagatagccaagcacaatccccgaatttccaaccaaca
ggctctaagattctatcgaatgtggctgcaagtcagcctgctcatataccagtgctcaaa
agagacctgaatgtgataacttctgtacccagcgagctatgtttacacgagatgtcccca
gatgcttcacttccaggggatccagaggcctatcctgctgctgtgtcaagcgatggaacc
attcatctgcagacaggaggtggatattttggcctaagctttacttgtcctagtctcaaa
aatcctattagcaggaaatcctggactcgaaaattaaaaagctgggcatacaggctacgg
cagtcaaccagctttttcaagagatcaaaagttcgtcaagtggaaacagaagataaaaga
tcagcaattgcttctgatcccattccgctgacacgggagttctcagctgatactagggct
ttgagtagatgtaaagcgatgagtggatcatttcagcggggtcggttccaggtgattaca
gttcctcagcagcagccagtgaaaatgatgtcttttggaaaagaacatagaccgccatcg
aagaaaacgacagcccagtctaacgagcaagcactaacctttactgaagctgcagtgaca
cagttgatcgaagtggaacctgccatacccactcataaagcttcagtttcttcacaaaag
ttacgaactctttatgaaacctttaaagaagataaaggagaccctgaacaaggtgacatc
ttatctttgagcacagctcgtgagaccagtgtgtcttcagtgacaacagaaaagaatgtg
gaagaaacttctactacaggaattagtgtgcagtctgggtctgaaatgttagataaagaa
aaagatgaatcaactcctgggaaacagacatgtactaatgaattttcagccactcctgct
ggcagtggaaagtcagtggcaaaagctgctccaaagagtggtcagcatttaccagcccgt
gctcaaacacagagttcactcttctactctccatcttctccaatgagcagtgacaatgaa
tcagaaatcgaggatgaggacttgaaagcggagcttcaaagattacgggaaaaacacatt
caagaggtggtcagtcttcaaacacagcagaataaagagctacaggagctctatgaacgc
cttcgagcaactaaagacagcaaagcgcaatcttcagaagttcccatgccacctgcatca
ccacgcaggccaagatccttcaaaagcaaacttcgaagccgcccccagtccttgacacat
tcggacaatctcgttgttgtaaaagatgtgcagcgtgcggagagtaatactgcgccacgc
cagcaatcgccagccagtaagaaggggatgttcacagatgatttacacaagctggtggat
gactggacaagagaaacagtaggaaattttcctagcaagccaagtttaaaccaactcaaa
cagagccaacaaaaatcagaggcagaaaactggaacaagttgcatgaaagcactccatct
actgtgggatacacatcaacctggatttcttctctctcccaaattcgcggagctgccccg
tcttccttgccacatggactcccactcccttcatttcctgggccattagcgtcctatgga
atgcctcatgcttgtcagtacaatcccgtaggcgccgcaagctatccagtacagtgggtt
gggatttcgggagcagcacagcaatccgtagtgcttcctacccaatctgggggactcttc
cagcctgggatgaatctgcagtcatttccagctccaccagtgcagaacccaccttcaatc
cctcctggtcccaaatga

  All links  
Gene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (12)   
   UniProt (1)   
   RefSeq(pep) (11)   
DNA sequence (11)   
   RefSeq(nuc) (11)   
Protein domain (4)   
   Pfam (4)   
All databases (32)   

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