KEGG   Rattus norvegicus (rat): 499689Help
Entry
499689            CDS       T01003                                 

Gene name
Gstm4
Definition
(RefSeq) glutathione S-transferase mu 4
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00480  Glutathione metabolism
rno00980  Metabolism of xenobiotics by cytochrome P450
rno00982  Drug metabolism - cytochrome P450
rno00983  Drug metabolism - other enzymes
rno01100  Metabolic pathways
rno01524  Platinum drug resistance
rno05200  Pathways in cancer
rno05204  Chemical carcinogenesis
rno05225  Hepatocellular carcinoma
rno05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    499689 (Gstm4)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    499689 (Gstm4)
   00982 Drug metabolism - cytochrome P450
    499689 (Gstm4)
   00983 Drug metabolism - other enzymes
    499689 (Gstm4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    499689 (Gstm4)
   05204 Chemical carcinogenesis
    499689 (Gstm4)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    499689 (Gstm4)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    499689 (Gstm4)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    499689 (Gstm4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:rno02000]
    499689 (Gstm4)
Enzymes [BR:rno01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     499689 (Gstm4)
Transporters [BR:rno02000]
 Other transporters
  Pores ion channels [TC:1]
   499689 (Gstm4)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: GST_N GST_C GST_C_3 GST_C_6 GST_N_3 GST_C_2 Bromo_TP
Motif
Other DBs
NCBI-GeneID: 499689
NCBI-ProteinID: NP_001019475
RGD: 1565825
Ensembl: ENSRNOG00000019221
UniProt: Q5BK56
Position
2q34
AA seq 218 aa AA seqDB search
MPMTLGYWDIRGLAHAIRLLLEYTDSSYEEKRYTMGDAPDYDRSQWLSEKFKLGLDFPNL
PYLIDGSHKITQSNAILRYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYSPDF
ENLKAEYLEQLPGMMELFSQFLGKQTWFVGEKITFVDFLAYDILDLHLIFEPKCLDAFPN
LKDFVARFEGLKKISVYMKTSRFLRTPLYTRVATWGNK
NT seq 657 nt NT seq  +upstreamnt  +downstreamnt
atgcctatgacactgggttactgggacatccgtgggctggctcatgctattcgattactc
ctggaatacacagactcaagctatgaggagaagagatacaccatgggcgacgctcctgac
tatgacagaagccagtggctgagtgagaagttcaaactgggcctggacttccccaatctg
ccctacttaatcgatgggtcacacaagatcacccagagcaatgccatcctgcgctatatt
gcccgaaagcacaacctgtgtggggagacagaagaagagaagattcgtgtggacattttg
gagaaccaggctatggatgtctccaatcagctggctagagtctgttacagcccagacttt
gagaacctgaaggcggaatatttggagcagctccctgggatgatggagctcttctcacag
ttcctggggaagcagacgtggttcgttggtgaaaagattacttttgtagatttccttgct
tatgatatcctggacctgcaccttatattcgaacccaagtgcctggatgccttcccaaac
ctgaaggactttgtggcccgcttcgagggactgaagaagatctctgtttacatgaagacc
agccgcttcctccggacacccctatatacaagggtggctacttggggcaataagtag

DBGET integrated database retrieval system