KEGG   Rattus norvegicus (rat): 499689Help
Entry
499689            CDS       T01003                                 

Gene name
Gstm4
Definition
(RefSeq) glutathione S-transferase mu 4
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00480  Glutathione metabolism
rno00980  Metabolism of xenobiotics by cytochrome P450
rno00982  Drug metabolism - cytochrome P450
rno00983  Drug metabolism - other enzymes
rno01100  Metabolic pathways
rno01524  Platinum drug resistance
rno05200  Pathways in cancer
rno05204  Chemical carcinogenesis
rno05225  Hepatocellular carcinoma
rno05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    499689 (Gstm4)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    499689 (Gstm4)
   00982 Drug metabolism - cytochrome P450
    499689 (Gstm4)
   00983 Drug metabolism - other enzymes
    499689 (Gstm4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    499689 (Gstm4)
   05204 Chemical carcinogenesis
    499689 (Gstm4)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    499689 (Gstm4)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    499689 (Gstm4)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    499689 (Gstm4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:rno02000]
    499689 (Gstm4)
Enzymes [BR:rno01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     499689 (Gstm4)
Transporters [BR:rno02000]
 Other transporters
  Pores ion channels [TC:1]
   499689 (Gstm4)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: GST_N GST_C GST_C_3 GST_C_6 GST_N_3 GST_C_2 Bromo_TP
Motif
Other DBs
NCBI-GeneID: 499689
NCBI-ProteinID: NP_001019475
RGD: 1565825
Ensembl: ENSRNOG00000019221
UniProt: Q5BK56
Position
2q34
AA seq 218 aa AA seqDB search
MPMTLGYWDIRGLAHAIRLLLEYTDSSYEEKRYTMGDAPDYDRSQWLSEKFKLGLDFPNL
PYLIDGSHKITQSNAILRYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYSPDF
ENLKAEYLEQLPGMMELFSQFLGKQTWFVGEKITFVDFLAYDILDLHLIFEPKCLDAFPN
LKDFVARFEGLKKISVYMKTSRFLRTPLYTRVATWGNK
NT seq 657 nt NT seq  +upstreamnt  +downstreamnt
atgcctatgacactgggttactgggacatccgtgggctggctcatgctattcgattactc
ctggaatacacagactcaagctatgaggagaagagatacaccatgggcgacgctcctgac
tatgacagaagccagtggctgagtgagaagttcaaactgggcctggacttccccaatctg
ccctacttaatcgatgggtcacacaagatcacccagagcaatgccatcctgcgctatatt
gcccgaaagcacaacctgtgtggggagacagaagaagagaagattcgtgtggacattttg
gagaaccaggctatggatgtctccaatcagctggctagagtctgttacagcccagacttt
gagaacctgaaggcggaatatttggagcagctccctgggatgatggagctcttctcacag
ttcctggggaagcagacgtggttcgttggtgaaaagattacttttgtagatttccttgct
tatgatatcctggacctgcaccttatattcgaacccaagtgcctggatgccttcccaaac
ctgaaggactttgtggcccgcttcgagggactgaagaagatctctgtttacatgaagacc
agccgcttcctccggacacccctatatacaagggtggctacttggggcaataagtag

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (10)   
   KEGG PATHWAY (10)   
Chemical substance (45)   
   KEGG COMPOUND (45)   
Chemical reaction (23)   
   KEGG ENZYME (1)   
   KEGG REACTION (22)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (10)   
   RefSeq(nuc) (2)   
   GenBank (4)   
   EMBL (4)   
Protein domain (7)   
   Pfam (7)   
All databases (108)   

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