KEGG   Rattus norvegicus (rat): 59323
Entry
59323             CDS       T01003                                 
Symbol
Erbb4
Name
(RefSeq) receptor tyrosine-protein kinase erbB-4 precursor
  KO
K05085  receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04010  MAPK signaling pathway
rno04012  ErbB signaling pathway
rno04020  Calcium signaling pathway
rno04151  PI3K-Akt signaling pathway
rno05014  Amyotrophic lateral sclerosis
rno05205  Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    59323 (Erbb4)
   04012 ErbB signaling pathway
    59323 (Erbb4)
   04020 Calcium signaling pathway
    59323 (Erbb4)
   04151 PI3K-Akt signaling pathway
    59323 (Erbb4)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    59323 (Erbb4)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    59323 (Erbb4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rno01001]
    59323 (Erbb4)
Enzymes [BR:rno01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     59323 (Erbb4)
Protein kinases [BR:rno01001]
 Receptor tyrosine kinases (RTK)
  EGFR family [OT]
   59323 (Erbb4)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Recep_L_domain GF_recep_IV Pkinase Furin-like TM_ErbB1 Kinase-like Haspin_kinase
Other DBs
NCBI-GeneID: 59323
NCBI-ProteinID: NP_067719
RGD: 620486
Ensembl: ENSRNOG00000014248
UniProt: Q62956
Position
9:complement(76973386..78045633)
AA seq 1308 aa
MKLATGLWVWGSLLVAARTVQPSASQSVCAGTENKLSSLSDLEQQYRALRKYYENCEVVM
GNLEITSIEHNRDLSFLRSIREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIF
LNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNMTLVST
IGSSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDGRCYGPYVSDCCHRECAGGCSG
PKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVD
SSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCT
KINGNLIFLVTGIHGDPYNAIDAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNL
VTIGGRVLYSGLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFST
VNQRIVIRDNRRAENCTAEGMVCNHLCSNDGCWGPGPDQCLSCRRFSRGKICIESCNLYD
GEFREFENGSICVECDSQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQGA
NSFIFKYADQDRECHPCHPNCTQGCNGPTSHDCIYYPWTGHSTLPQHARTPLIAAGVIGG
LFILVIMALTFAVYVRRKSIKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKR
VKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASVDHPHL
VRLLGVCLSPTIQLVTQLMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLV
HRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQ
SDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMID
ADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAE
EYLVPQAFNIPPPIYTSRTRIDSNRSEIGHSPPPAYTPMSGNQFVYQDGGFATQQGMPMP
YRATTSTIPEAPVAQGATAEMFDDSCCNGTLRKPVVPHVQEDSSTQRYSADPTVFAPERN
PRAELDEEGYMTPMHDKPKQEYLNPVEENPFVSRRKNGDLQALDNPEYHSASSGPPKAED
EYVNEPLYLNTFTNALGNAEYMKNSLLSVPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQ
EYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTMLPPPPYRHRNTVV
NT seq 3927 nt   +upstreamnt  +downstreamnt
atgaagctggcgacgggactgtgggtctgggggagccttctggtggcagccaggaccgtc
cagcccagcgcttctcagtcagtgtgtgccggaacagagaacaaactgagctctctctct
gatctggagcagcagtaccgagccttgcgcaaatactatgaaaactgcgaggtagtcatg
ggcaacctggagatcaccagcatagagcacaaccgggacctctccttcctgcggtctatc
cgagaagtcacaggctatgtacttgtggccctcaaccagtttcgttacctgcctctggag
aatttacgcattattcgtgggacaaaactgtatgaagatcgctatgccttagcaatattc
ttaaactacaggaaagatggcaactttggacttcaagaactgggattaaagaacctgacc
gaaatactaaatggtggagtctatgtagaccagaacaaattcctatgttatgctgatact
atacactggcaagatattgttcggaatccatggccttccaacatgactctggtgtcaaca
attggaagttctggatgcggaagatgccataagtcttgcactggtcgatgctggggaccc
acagaaaatcactgccagaccttgaccaggactgtgtgtgctgaacaatgtgatggcagg
tgctatggaccctacgtcagtgactgctgccatcgagaatgtgccggaggctgctcagga
ccaaaagacactgactgctttgcctgcatgaacttcaatgacagtggagcctgtgttact
cagtgtccccaaacgttcgtctacaatccaaccacctttcaactggaacacaacttcaat
gcaaagtacacatatggagcattctgtgttaagaaatgtccacataacttcgtggtagat
tccagttcttgtgtacgagcctgccctagttccaagatggaagtcgaagaaaatggaatt
aaaatgtgtaagccttgcactgatatttgccccaaagcatgtgatggaatcggcaccgga
tccttgatgtctgctcagactgtggattccagtaacattgacaaattcataaactgcacc
aagatcaacgggaatctcatctttcttgtcactggcattcatggtgacccttacaatgct
attgacgccatagacccagagaaactgaatgtctttcggacagtcagagaaataacaggt
ttcctgaacatacaatcttggcccccaaatatgacagatttcagtgttttctccaacctt
gtaaccattggaggaagagtcctctacagtggtctctcattgcttatcctcaaacaacaa
ggtatcacttcactacagttccagtctctgaaggaaatcagtgcgggcaatatctacatc
acggacaacagcaacctgtgttattaccacaccatcaactggacaacactgttcagcacc
gttaaccagaggatagtgatccgagacaacaggagggctgagaactgtactgctgaaggg
atggtgtgtaaccacctgtgttcaaatgatggttgttggggacctgggccagaccagtgt
ctgtcatgtcggcgcttcagcaggggaaagatctgtatagagtcctgcaacctttatgat
ggggagtttcgagagtttgaaaacggctccatctgtgttgagtgtgactcccagtgtgag
aaaatggaagacggactcctcacatgccatggaccgggacctgacaactgtacaaagtgt
tctcattttaaagatggtcctaactgtgtagagaaatgtccagatggcctacagggagca
aacagtttcatatttaagtacgcagatcaggatcgggagtgccacccttgccatccaaac
tgcacccaggggtgtaacggtcccactagtcatgactgcatttactacccatggacgggc
cattccactttaccacaacatgctagaactccactgattgcagccggagtcattggaggg
ctcttcatcctggtcatcatggctctgacatttgccgtttatgtcagaaggaagagcatc
aaaaagaaacgcgctttgagaagattcctggagacagagctagtcgagcccttaacccct
agtggcacagcacccaatcaagctcaacttcgaattttgaaggaaacagagctaaagagg
gtaaaagtccttggctcgggagcatttggaaccgtttataaaggaatctgggtgcctgaa
ggtgaaactgtgaaaatccctgtggctattaagatcctcaatgagacaactggccccaaa
gccaatgtggagttcatggatgaggcactgattatggcaagtgtggatcacccacaccta
gtgcgtttactgggtgtgtgtctgagccccactatccagttggttactcagttgatgcca
catggctgcctactggaatatgtccacgaacacaaggataacatcggatcacagctgctg
ttgaactggtgtgtccagattgctaagggaatgatgtatctggaggaaaggcggcttgtt
catcgggatctggcagcccgcaatgtgttggtgaaatctccaaatcatgttaaaatcaca
gactttggactggcccggctcttggaaggagatgaaaaagaatacaatgctgacggtggc
aagatgccaattaaatggatggctctggaatgtatacattataggaaattcacacatcaa
agcgatgtttggagctacggtgtcactatatgggaactgatgacctttggaggaaagccc
tatgatggaattccaacgcgagaaatccctgacttattagagaagggagagcgtttgcct
caacctcccatctgcactattgacgtttacatggtcatggtcaaatgttggatgatcgat
gctgacagcagacctaaattcaaagaactggctgctgagttttcaaggatggctagagac
cctcaaagatacctagtaattcagggggatgatcgcatgaagcttcccagtccaaacgac
agcaaattcttccagaatctcttggatgaagaggatttggaagatatgatggacgctgag
gaatatttggtcccccaggctttcaatatcccacctcctatctacacatccagaacaaga
attgactccaataggagtgaaattggacacagccctcctcctgcctacacccccatgtcg
ggaaatcagtttgtgtaccaggatgggggtttcgctacacaacaaggaatgcccatgccc
taccgagccacaaccagcaccataccagaggctccagtcgcccagggtgcaacggctgag
atgtttgatgactcctgctgtaatggtaccctgcgaaagccagtggtaccccacgtccaa
gaggacagtagcactcagaggtatagtgccgaccccacagtgttcgccccagaacggaac
cctcgagcagaactggatgaagaaggctacatgactcccatgcatgacaagccaaaacaa
gaatatctgaatcctgtggaagagaacccttttgtgtcccggaggaagaatggagacctt
caagctttagataatccagagtatcacagcgcttccagcggtccccccaaggcagaggat
gagtacgtgaatgagcccctttatctcaacaccttcaccaacgccttgggaaatgcagag
tacatgaaaaacagcttactgtctgtgccagagaaagccaagaaagcatttgacaacccc
gactactggaaccacagcctgccaccccggagcactcttcagcacccagactacctgcag
gaatacagcacaaaatatttttataaacagaatggacggatccgccctattgtggcagag
aatcctgagtacctctcagagttctcgctgaagccaggcactatgctgccccctccgccc
tacagacaccggaatactgtggtgtga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (6)   
   KEGG PATHWAY (6)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (7)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (15)   
   RefSeq(nuc) (5)   
   GenBank (5)   
   EMBL (5)   
Protein domain (8)   
   Pfam (8)   
All databases (47)   

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